CD33 - CD33 molecule Gene

Also Known as p67; SIGLEC3; SIGLEC-3

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 945

About CD33

Cytogenetic location: 19q13.41 Genomic coordinates (GRCh38): 19:51,211,076-51,240,016 (from NCBI)

This gene has 7 transcripts (splice variants), 73 orthologues and 16 paralogues. Broad expression in spleen (RPKM 7.5), bone marrow (RPKM 6.6) and 19 other tissues.

Summary

Enables protein Phosphatase binding activity and sialic acid binding activity. Involved in several processes, including negative regulation of cytokine production; negative regulation of monocyte activation; and positive regulation of protein tyrosine Phosphatase activity. Located in several cellular components, including Golgi apparatus; external side of plasma membrane; and peroxisome. [provided by Alliance of Genome Resources, Apr 2022]

CD33 Products (3)

mRNA Protein Name
NM_001082618.2 NP_001076087.1 myeloid cell surface antigen CD33 isoform 2
NM_001177608.2 NP_001171079.1 myeloid cell surface antigen CD33 isoform 3 precursor
NM_001772.4 NP_001763.3 myeloid cell surface antigen CD33 isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
10206955 GOA
enables protein phosphatase binding IPI
IPI: Inferred from physical interaction
10556798 GOA
enables protein tyrosine phosphatase activator activity IMP
IMP: Inferred from mutant phenotype
10556798 GOA
enables sialic acid binding IMP
IMP: Inferred from mutant phenotype
7718872 GOA
Biological Process GO Annotation Evidence 参考文献 由来
involved in Fc-gamma receptor signaling pathway IDA
IDA: Inferred from direct assay
10556798 GOA
involved in cell-cell adhesion IMP
IMP: Inferred from mutant phenotype
7718872 GOA
involved in immune response-inhibiting signal transduction IDA
IDA: Inferred from direct assay
10887109 GOA
involved in negative regulation of interleukin-1 beta production IMP
IMP: Inferred from mutant phenotype
15597323 GOA
involved in negative regulation of interleukin-8 production IMP
IMP: Inferred from mutant phenotype
15597323 GOA
involved in negative regulation of monocyte activation IDA
IDA: Inferred from direct assay
15597323 GOA
involved in negative regulation of tumor necrosis factor production IMP
IMP: Inferred from mutant phenotype
15597323 GOA
involved in positive regulation of protein secretion IMP
IMP: Inferred from mutant phenotype
27044754 GOA
Cellular Component GO Annotation Evidence 参考文献 由来
located in Golgi apparatus IDA
IDA: Inferred from direct assay
21278227 GOA
located in cell surface IDA
IDA: Inferred from direct assay
28747436 GOA
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
20660734 GOA
located in peroxisome IDA
IDA: Inferred from direct assay
28747436 GOA
located in plasma membrane IDA
IDA: Inferred from direct assay
21278227 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CD33 Protein Structure

V-set

V-set: Immunoglobulin V-set domain (23 - 136)

ig

ig: Immunoglobulin domain (156 - 214)

  • 0
  • 100
  • 200
  • 300
  • 364 a.a.
Protein Preferred Names Protein Names

myeloid cell surface antigen CD33

  • CD33 antigen (gp67)

CD33 Protein-protein interaction Information

Type
タンパク質名 Protein ID Interactor Interactor Species Interactor ID Detection Method 参考文献
Intra
CD33 P20138 KRT40 Homo sapiens Q6A162
Y2H Array
25416956
Intra
CD33 P20138 KRT40 Homo sapiens Q6A162
Validated Y2H
25416956
Intra
CD33 P20138 TTMP Homo sapiens Q5BVD1
Validated Y2H
32296183
Intra
CD33 P20138 RPRM Homo sapiens Q9NS64
Validated Y2H
32296183
Intra
CD33 P20138 S100A9 Homo sapiens P06702
Affinity Chrom
24216507
Intra
CD33 P20138 S100A9 Homo sapiens P06702
IF
24216507
Intra
CD33 P20138 S100A9 Homo sapiens P06702
ELISA
24216507
Intra
CD33 P20138 S100A9 Homo sapiens P06702
Anti Bait CoIP
24216507
Intra
CD33 P20138 KRT35 Homo sapiens Q92764
Validated Y2H
32296183
Intra
CD33 P20138 KRT35 Homo sapiens Q92764
Y2H Prey Pooling
32296183
Intra
CD33 P20138 KRT35 Homo sapiens Q92764
Y2H Array
32296183
Intra
CD33 P20138 TNMD Homo sapiens Q9H2S6-2
Validated Y2H
32296183
Intra
CD33 P20138 TMEM243 Homo sapiens Q9BU79
Validated Y2H
32296183
Intra
CD33 P20138 TMEM243 Homo sapiens Q9BU79
Y2H Array
32296183
Intra
CD33 P20138 UBIAD1 Homo sapiens Q9Y5Z9
Validated Y2H
32296183
Intra
CD33 P20138 TMBIM1 Homo sapiens Q969X1
Validated Y2H
32296183
Intra
CD33 P20138 PTPN11 Homo sapiens Q06124
Anti Bait CoIP
17947393
Intra
CD33 P20138 PTPN11 Homo sapiens Q06124
Pull Down
17947393
Intra
CD33 P20138 THSD7A Homo sapiens Q9UPZ6
Validated Y2H
32296183
Intra
CD33 P20138 CXCL9 Homo sapiens Q07325
Validated Y2H
32296183
Intra
CD33 P20138 EMD Homo sapiens P50402
Validated Y2H
32296183
Intra
CD33 P20138 GIMAP5 Homo sapiens Q96F15
Validated Y2H
32296183
Intra
CD33 P20138 PTPN6 Homo sapiens P29350
Pull Down
10206955
Intra
CD33 P20138 PTPN6 Homo sapiens P29350
Pull Down
17947393
Intra
CD33 P20138 PTPN6 Homo sapiens P29350
Anti Bait CoIP
17947393
Intra
CD33 P20138 PTPN6 Homo sapiens P29350
Anti Bait CoIP
24216507
Intra
CD33 P20138 TMEM100 Homo sapiens Q9NV29
Validated Y2H
32296183
Intra
CD33 P20138 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
25416956
Intra
CD33 P20138 KRT31 Homo sapiens Q15323
Validated Y2H
32296183
Intra
CD33 P20138 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
Intra
CD33 P20138 KRT31 Homo sapiens Q15323
Y2H Array
32296183
Intra
CD33 P20138 KRT31 Homo sapiens Q15323
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant CD33 Proteins

製品番号 製品名 アクセッション番号 純度
HY-P72021 Siglec-3/CD33 Protein, Human (HEK293, Fc-Myc) P20138-1 (D18-H259) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P72472 Siglec-3/CD33 Protein, Human (HEK293, Fc-His) AAH28152.1 (D18-H259) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P73642 Siglec-3/CD33 Protein, Human (HEK293, hFc) P20138-1/AAH28152.1 (D18-H259, R69G) ≥ 95%, as determined by Bis-Tris PAGE.
HY-P73643 Siglec-3/CD33 Protein, Human (HEK293) AAH28152 (D18-H259) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P73644 Siglec-3/CD33 Protein, Human (HEK293, His) AAH28152 (D18-H259) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P77536 Siglec-3/CD33 Protein, Human (Biotinylated, HEK293, His) AAH28152 (D18-H259) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P78407 Siglec-3/CD33 Protein, Human (HEK293, His-Avi) P20138-1 (D18-H259) ≥ 95%, as determined by Bis-Tris PAGE.
HY-P78408 FITC-Labeled Siglec-3/CD33 Protein, Human (HEK293, His-Avi) P20138-1 (D18-H259) ≥ 95%, as determined by Bis-Tris PAGE.
HY-P701037 Siglec-3/CD33 Protein, Human (Biotinylated, HEK293, His-Avi) P20138-1 (D18-H259) ≥ 95%, as determined by reducing SDS-PAGE.

CD33 抗体

製品番号 製品名 アプリケーション 反応性
HY-P81563 CD33 Antibody (YA1308) IHC-P, FC Human
HY-P84163 CD33 Antibody (YA3860) WB, IHC-P, FC, ELISA Human
HY-P84163A CD33 Antibody (YA3860)(PBS only) WB, IHC-P, FC, ELISA Human
HY-P84989 CD33 Antibody (YA4681) ELISA, FC Human
HY-P85023 CD33 Antibody (YA4715) FC, ELISA Human
HY-P85088 CD33 Antibody (YA4780) WB, ELISA Human

関連疾患

Diseases Alias
Childhood T-Cell Acute Lymphoblastic Leukemia

  • T-Cell Childhood Acute Lymphoblastic Leukemia

  • Childhood Precursor T-Lymphoblastic Lymphoma/Leukemia

  • T-Cell Childhood Acute Lymphocytic Leukemia

  • Childhood T Lymphoblastic Leukemia/Lymphoma
Acute Promyelocytic Leukemia

  • Leukemia, Acute Promyelocytic

  • Acute Myeloblastic Leukemia Type 3

  • Aml M3

  • APL

  • Leukemia, Acute Promyelocytic, Somatic

  • Aml With T(15

  • 17)(Q22

  • Q12)

  • (Pml/Raralpha) And Variants

  • Apml

  • Acute Myeloblastic Leukemia 3

  • Acute Myeloid Leukemia With T(15

  • 17)(Q22

  • Q12)

  • (Pml/Raralpha) And Variants

  • Acute Myeloblastic Leukaemia Type 3

  • Acute Myeloid Leukaemia M3

  • Acute Myeloid Leukemia M3

  • Acute Promyelocytic Leukaemia

  • M3 Anll

  • Myeloid Leukemia, Acute, M3

  • Leukemia Promyelocytic Acute

  • Leukemia, Promyelocytic, Acute

  • Leukemia, Acute, Promyelocytic
Myeloid Leukemia

  • Myeloid Leukaemia

  • Leukaemia Myelogenous

  • Leukemia Myelogenous

  • Myeloid Granulocytic Leukaemia

  • Myeloid Granulocytic Leukemia

  • Non-Lymphocytic Leukemia

  • Leukemia, Myeloid

  • Granulocytic Leukaemia

  • Myelogenous Leukaemia

  • Myeloid Leukaemia, Unspecified, Without Mention Of Remission
Myelodysplastic Syndrome

  • Myelodysplastic Syndromes

  • Myelodysplasia

  • MDS

  • Myelodysplastic Syndrome Included

  • Myelodysplastic Syndrome, Susceptibility To, Included

  • Myelodysplastic Syndrome, Somatic

  • Myelodysplastic Syndrome, Susceptibility To
Acute Biphenotypic Leukemia

  • Mixed Phenotype Acute Leukemia

  • Acute Leukemia Of Ambiguous Lineage

  • Acute Undifferentiated Leukemia

  • Acute Leukemia Of Indeterminate Lineage

  • Hybrid Acute Leukemia

  • Mixed Lineage Acute Leukemia

  • All With Myeloid Markers

  • Aml With Lymphoid Markers

  • Acute Leukemia Of Undetermined Lineage

  • Bal

  • Biphenotypic Acute Leukemia

  • Undifferentiated Acute Leukemia

  • Mpal

  • Acute Myeloid Leukemia, Minimal Differentiation, Fab M0

  • Leukemia, Biphenotypic, Acute
Acute Basophilic Leukemia
Myeloid Sarcoma

  • Granulocytic Sarcoma

  • Chloroma

  • Extramedullary Myeloid Tumor

  • Sarcoma, Granulocytic

  • Sarcoma Granulocytic

  • Sarcoma, Myeloid

  • Myelosarcoma

  • Myeloid Sarcoma Disease

  • Myeloid Sarcoma Nos

  • Myeloid Sarcoma Without Mention Of Remission
Central Nervous System Leukemia

  • Leukemia Of The Cns
Leukemia, Chronic Myeloid

  • Chronic Myeloid Leukemia

  • Chronic Myelogenous Leukemia

  • CML

  • Chronic Granulocytic Leukemia

  • Leukemia, Philadelphia Chromosome-Positive, Resistant To Imatinib

  • Chronic Myeloid Leukaemia

  • Chronic Granulocytic Leukaemia

  • Chronic Myelogenous Leukaemia

  • Myeloid Leukemia, Chronic

  • Leukemia, Chronic Myelogenous

  • Leukemia, Chronic Myeloid, Philadelphia Chromosome Positive, Somatic

  • Cml - Chronic Myelogenous Leukemia

  • Cgl

  • Chronic Myelocytic Leukemia

  • Leukemia, Chronic Myeloid, Atypical

  • ACML

  • Atypical Chronic Myeloid Leukemia Bcr-Abl1 Negative

  • Myeloid Leukemia Chronic

  • Leukemia, Myeloid, Chronic

  • Leukemia, Myeloid, Chronic, Atypical, Bcr-Abl Negative

  • Cml- [Chronic Myeloid Leukaemia]

  • Cgl - [Chronic Granulocytic Leukaemia]

  • Chronic Myelocytic Leukaemia
Leukemia, Acute Lymphoblastic

  • Acute Lymphoblastic Leukemia

  • ALL

  • Acute Lymphocytic Leukemia

  • Leukemia, Acute Lymphocytic, Susceptibility To, 1

  • Acute Lymphoblastic Leukaemia

  • Precursor Lymphoblastic Lymphoma/Leukemia

  • Precursor Lymphoid Neoplasm

  • Leukemia, Acute Lymphoblastic, Susceptibility To

  • B-Cell Acute Lymphoblastic Leukemia

  • Leukemia, Acute Lymphocytic 1

  • Acute Lymphocytic Leukaemia

  • Acute Lymphoblastic Leukemia/Lymphoma

  • All1

  • Childhood Acute Lymphoblastic Leukemia

  • Leukemia Acute Lymphoblastic 1

  • Leukemia Acute Lymphoblastic B-Hyperdiploid

  • Leukemia Acute Lymphocytic

  • Leukemia Acute Lymphocytic 1

  • Leukemia B-Cell Acute Lymphoblastic

  • Leukemia T-Cell Acute Lymphoblastic

  • Leukemia, Acute Lymphoblastic, 3

  • ALL3

  • Lymphoblastic Leukemia Acute

  • Leukemia, Acute, Lymphoblastic

  • Precursor Cell Lymphoblastic Leukemia Lymphoma

  • Leukemia, Lymphocytic, Acute, L1

  • Leukemia, Acute Lymphoblastic, Susceptibility To, 3
Hepatic Veno-Occlusive Disease

  • Veno-Occlusive Disease

  • Sinusoidal Obstruction Syndrome

  • Hepatic Venoocclusive Disease

  • Venoocclusive Disease

  • Hepatic Vein Thrombosis

  • Budd-Chiari Syndrome

  • Hepatic Vein Occlusion

  • Veno-Occlusive Disease Of The Liver
Myeloproliferative Syndrome, Transient

  • Transient Abnormal Myelopoiesis

  • Transient Myeloproliferative Syndrome

  • Transient Myeloproliferative Disease

  • Mst

  • Tam

  • Leukemia, Transient, Of Down Syndrome

  • Tmd

  • Leukemia, Transient

  • Transient Leukemia

  • Transient Leukemia Of Down Syndrome
Polycystic Lipomembranous Osteodysplasia With Sclerosing Leukoencephalopathy 1

  • Nasu-Hakola Disease

  • Polycystic Lipomembranous Osteodysplasia With Sclerosing Leukoencephalopathy

  • Plosl

  • Nhd

  • Presenile Dementia With Bone Cysts

  • Plo-Sl

  • PLOSL1

  • Dementia, Prefrontal, With Bone Cysts

  • Dementia, Progressive, With Lipomembranous Polycystic Osteodysplasia

  • Brain-Bone-Fat Disease

  • Progressive Dementia With Lipomembranous Polycystic Osteodysplasia

  • Brain-Bone-Fat Disease
Malignant Giant Cell Tumor Of The Tendon Sheath

  • Giant Cell Tumour Of Tendon Sheath, Malignant

  • Malignant Giant Cell Neoplasm Of The Tendon Sheath
Childhood Acute Myeloid Leukemia

  • Childhood Acute Myeloid Leukaemia

  • Paediatric Acute Myeloid Leukaemia

  • Pediatric Acute Myeloid Leukemia
B-Cell Adult Acute Lymphocytic Leukemia

  • Adult B Acute Lymphoblastic Leukemia

  • Adult B Acute Lymphoblastic Leukaemia

  • Adult B-Cell Acute Lymphoblastic Leukaemia

  • Adult B-Cell Acute Lymphoblastic Leukemia

  • Adult B-Cell Lymphocytic Leukaemia

  • Adult B-Cell Lymphocytic Leukemia

  • Adult B-Lymphoblastic Leukaemia

  • Adult B-Lymphoblastic Leukemia

  • B-Cell Adult Acute Lymphocytic Leukaemia

  • B-Cell Adult Acute Lymphoblastic Leukemia
B-Lymphoblastic Leukemia/Lymphoma

  • B Lymphoblastic Leukemia/Lymphoma

  • B-All

  • Precursor B Lymphoblastic Lymphoma/Leukemia

  • C-All

  • Lymphoblastic Lymphoma, Nos

  • Common Precursor B All

  • Lymphoblastic B-Cell Lymphoma

  • Pro-B All

  • B-Precursor Lymphoma

  • Lbl - [Lymphoblastic Lymphoma]
Hepatic Vascular Disease

  • Vascular Disorder Of Liver
Adult Acute Lymphocytic Leukemia

  • Adult Acute Lymphoid Leukemia

  • Adult All
Chronic Leukemia

  • Adult Chronic Leukemia

  • Cll

  • Cml
Childhood Leukemia
Acute Myeloid Leukemia With Bcr-Abl1

  • Acute Myeleoid Leukemia With Bcr-Abl1
Leukemia, Acute Monocytic

  • Acute Monocytic Leukemia

  • Acute Monoblastic Leukemia And Acute Monocytic Leukemia

  • Acute Monocytic Leukaemia

  • Acute Monocytic Leukaemia Without Mention Of Remission

  • Acute Monocytic Leukemia Without Mention Of Remission

  • Acute Monocytic Leukemia, Fab M5

  • Acute Monocytic Leukemia, Morphology

  • Leukemia, Monocytic, Acute

  • M5b Acute Differentiated Monocytic Leukemia
Bone Marrow Cancer

  • Malignant Neoplasm Of Bone Marrow

  • Bone Marrow Neoplasm

  • Bone Marrow Tumor

  • Malignant Bone Marrow Tumor

  • Myeloproliferative Disorders

  • Bone Marrow Neoplasms

  • Myeloproliferative Disease

  • Chronic Myeloproliferative Disorder
Precursor T-Cell Acute Lymphoblastic Leukemia

  • T-All

  • Precursor T-Cell Acute Lymphoblastic Leukemia/Lymphoma

  • Precursor T-Cell Acute Lymphocytic Leukemia

  • Precursor T-Cell Acute Lymphocytic Leukemia/Lymphoma

  • Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

  • Adult T-Cell Lymphoma/Leukemia
Pancytopenia
Chronic Myelomonocytic Leukemia

  • Leukemia, Myelomonocytic, Chronic

  • Cmml

  • Leukemia Myelomonocytic Chronic

  • Cmml - [Chronic Myelomonocytic Leukaemia]

  • Chronic Myelomonocytic Leukaemia Without Mention Of Remission

  • Chronic Monocytic Leukaemia

  • Chronic Monocytoid Leukaemia
Bronchiectasis 1
Cardiomyopathy, Dilated, 1c, With Or Without Left Ventricular Noncompaction

  • Left Ventricular Noncompaction 3

  • Dilated Cardiomyopathy 1c

  • CMD1C

  • Cardiomyopathy, Hypertrophic, 24

  • Dilated Cardiomyopathy With Left Ventricular Noncompaction

  • Cardiomyopathy, Dilated, 1c, With Or Without Lvnc

  • Cmdc1

  • Dilated Cardiomyopathy 1c With Or Without Left Ventricular Noncompaction

  • Cardiomyopathy, Dilated 1c, With Or Without Left Ventricular Non-Compaction

  • Cardiomyopathy Dilated With Left Ventricular Noncompaction

  • Cardiomyopathy, Familial Hypertrophic 24

  • CMH24

  • Left Ventricular Non-Compaction 3

  • LVNC3

  • Cardiomyopathy, Dilated 1c

  • Familial Hypertrophic Cardiomyopathy 24

  • Cardiomyopathy, Dilated, 1c
Leukemia, Acute Myeloid

  • Acute Myeloid Leukemia

  • Leukemia, Acute Myelogenous

  • Acute Myelogenous Leukemia

  • AML

  • Leukemia, Acute Myeloid, Susceptibility To

  • Acute Myeloblastic Leukemia

  • Leukemia, Acute Myeloid, Reduced Survival In, Somatic

  • Acute Myeloid Leukaemia

  • Leukemia, Myelocytic, Acute

  • Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome

  • Secondary Aml

  • Acute Myelocytic Leukemia

  • Acute Myeloid Leukemia, Somatic

  • Leukemia, Acute Myeloid, Somatic

  • Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic

  • Acute Myeloblastic Leukaemia

  • Acute Myelogenous Leukaemia

  • Aml - Acute Myeloid Leukemia

  • Acute Myeloid Leukemia With Cebpa Somatic Mutations

  • Aml With Cebpa Somatic Mutations

  • Inherited Acute Myeloid Leukemia

  • Familial Aml

  • Inherited Aml

  • Pure Familial Aml

  • Pure Familial Acute Myeloid Leukemia

  • Secondary Acute Myeloid Leukemia

  • Therapy-Related Aml And Myelodysplastic Syndrome

  • Acute Myeloid Leukemia, Secondary

  • Acute Non-Lymphoblastic Leukemia

  • Acute Non-Lymphocytic Leukemia

  • Acute Biphenotypic Leukemia

  • Acute Undifferentiated Leukemia

  • Acute Myeloblastic Leukaemia With Multilineage Dysplasia

  • Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission

  • Acute Myeloid Leukaemia With Myelodysplasia-Related Features
Acute Megakaryocytic Leukemia

  • Acute Megakaryoblastic Leukemia

  • Acute Megakaryoblastic Leukaemia

  • Megakaryocytic Myelosis

  • Thrombocytic Leukaemia

  • Amkl

  • Aml M7

  • Acute Myeloblastic Leukemia Type 7

  • Acute Myeloid Leukemia M7

  • Megakaryoblastic Leukemia Acute

  • Leukemia, Megakaryoblastic, Acute

  • Acute Myeloid Leukaemia, M7

  • Acute Megakaryocytic Leukaemia

  • Acute Megakaryoblastic Leukaemia, Fab M7

  • Fab M7

  • Malignant Megakaryocytosis

  • M7 - Acute Megakaryoblastic Leukaemia

  • Megakaryoblastic Leukaemia

  • Megakaryocytic Leukaemia

  • Acute Megakaryoblastic Leukaemia, Nos

  • Acute Megakaryoblastic Leukaemia Without Mention Of Remission
Blood Platelet Disease

  • Platelet Disorder

  • Blood Platelet Disorders

  • Thrombocytopathy

  • Platelet Dysfunction

  • Platelet Disorders

  • Qualitative Platelet Deficiency
Juvenile Myelomonocytic Leukemia

  • Leukemia, Juvenile Myelomonocytic

  • JMML

  • Leukemia, Juvenile Myelomonocytic, Somatic

  • Juvenile Chronic Myelomonocytic Leukemia

  • Juvenile Chronic Myelogenous Leukemia

  • Leukemia, Myelomonocytic, Juvenile

  • Juvenile Myelomonocytic Leukaemia Without Mention Of Remission
Myeloma, Multiple

  • Multiple Myeloma

  • Plasma Cell Myeloma

  • Kahler Disease

  • Myelomatosis

  • Medullary Plasmacytoma

  • Multiple Myeloma, Resistance To

  • Myeloma

  • Plasma Cell Dyscrasia

  • Kahler'S Disease

  • Multiple Myeloma, Susceptibility To

  • Myeloma - Multiple

  • Kahler-Bozzolo Disease

  • Plasma Cell Myelomas

  • MM

  • Plasma Cell Neoplasm

  • Primary Systemic Amyloidosis

  • Primary Amyloidosis

  • Immunoglobulin Deposition Disease

  • Plasmacytic Myeloma

  • Multiple Myelomata

  • Multiple Myeloma Nos

  • Multiple Myeloma Without Mention Of Remission

  • Monostotic Plasma Cell Myeloma

  • Mm - [Multiple Myeloma]
Bilirubin Metabolic Disorder

  • Hyperbilirubinemia

  • Hereditary Hyperbilirubinemia

  • Hyperbilirubinemia, Hereditary

  • Hyperbilirubinaemia
Leukemia, Chronic Lymphocytic

  • Chronic Lymphocytic Leukemia

  • B-Cell Chronic Lymphocytic Leukemia

  • CLL

  • B-Cell Chronic Lymphoid Leukemia

  • Chronic Lymphatic Leukemia

  • Chronic Lymphocytic Leukaemia

  • Lymphoplasmacytic Leukemia

  • Small Lymphocytic Lymphoma

  • Leukemia, Chronic Lymphatic

  • B-Cell Chronic Lymphocytic Leukaemia

  • Chronic Lymphatic Leukaemia

  • Lymphoplasmacytic Leukaemia

  • B Cell Chronic Lymphocytic Leukemia

  • Chronic B-Cell Lymphocytic Leukemia

  • Leukemia, Lymphocytic, Chronic

  • B-Cll

  • Chronic Lymphoid Leukemia

  • Leukemia Lymphocytic Chronic

  • Lymphoma Small Lymphocytic

  • Leukemia, Lymphocytic, Chronic, B-Cell
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
製品番号 製品名 製品効果
純度 Rare Diseases
HY-109539 Gemtuzumab ozogamicin Inducer 98.00% Unkown

Clinical Phase

Bioactive Molecules (1)
製品番号 製品名 製品効果
純度 Phase
HY-171792 BMS-986497 Inhibitor / Phase 1
阻害性抗体 (6)
製品番号 製品名 製品効果
純度 Phase
HY-P99971 Gemtuzumab 99.54% Phase 4
HY-P99329 Vadastuximab 99.23% Phase 3
HY-P9983 Lintuzumab Inhibitor 98.09% Phase 3
HY-P99910 Eluvixtamab Ligand 97.28% Phase 1
HY-P99958 Vixtimotamab Inhibitor 97.29% Phase 1
HY-P991364 Aldastotug Inhibitor 99.9% Phase 1

Pre-clinical Phase

Bioactive Molecules (7)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-144399 CD33 splicing modulator 1 Inhibitor 99.05% Unkown
HY-160649 MC-Gly-Gly-Phe-Gly-GABA-Exatecan Inhibitor 99.72% Unkown
HY-109539A Gemtuzumab ozogamicin (solution) Inducer / Unkown
HY-144399A CD33 splicing modulator 1 hydrochloride Modulator / Unkown
HY-RS02235 CD33 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17093 Cd33 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23537 Cd33 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
阻害性抗体 (5)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-P990903 Avitotamig Inhibitor 95.98% Unkown
HY-P991365 DS-1501 Inhibitor / Unkown
HY-P990505 Anti-Siglec-15/CD33L3 Antibody Inhibitor 98.6674% Unkown
HY-P991517 BI-836858 95.81% Unkown
HY-P9S0124 Anti-CD33 Antibody (OR000283) 99.00% Unkown

Orthologs Information

生物種 Symbol 由来 ID
Mus musculus CD33 MGD MGI:99440
Rattus norvegicus CD33 RGD RGD:1596020
Macaca mulatta CD33 VGNC VGNC:81368
Others CD33 NCBI