Largazole thiol
Largazole thiol, the active form of Largazole (HY-13906), is a potent, selective and brain-penetrant class I HDAC inhibitor. Largazole thiol. Largazole thiol exerts antitumor and neuroprotective effects. Largazole thiol can be used for research of Glioblastoma.
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- CAS 番号: 1132667-11-8
- 分子式: C21H28N4O4S3
- 分子量:496.67
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
5.9 nM
Compound: 2
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Antiproliferative activity against human HCT116 cells after 48 hrs in absence of DTT by MTT assay
Antiproliferative activity against human HCT116 cells after 48 hrs in absence of DTT by MTT assay
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[PMID: 25147612] |
化学情報
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CAS 番号 1132667-11-8
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分子量 496.67
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分子式 C21H28N4O4S3
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SMILES
C[C@@]12N=C(SC2)C3=CSC(CNC(C[C@H](OC([C@H](NC1=O)C(C)C)=O)/C=C/CCS)=O)=N3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Largazole thiol 関連分類
HY-170890 関連分類
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