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Potassium sorbate (Sorbic acid potassium) is an antibacterial preservative effective against most molds, yeasts, and some bacterial species. Potassium sorbate inhibits microbial growth. Potassium sorbate suppresses the activity of intestinal microorganisms in zebrafish, alters the composition of intestinal flora, and reduces the levels of intestinal immune biomarkers, including IgG, IL-1β, and TNF-α. Potassium sorbate can be used in research on the prevention and treatment of mold, yeast, and bacterial infections.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.0%
- CAS 番号: 24634-61-5
- 分子式: C6H7KO2
- 分子量:150.22
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保管条件:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
生物活性
Potassium sorbate (0.05%-0.1%) extends the shelf life of cottage cheese, inhibits the growth of Penicillium frequentans and other spoilage microorganisms, suppresses spoilage bacteria in cottage cheese as well as molds in unsalted butter and grains, and prolongs the safe storage period of grains[1].
Potassium sorbate (0.02%-0.04%) inhibits the growth of molds in ham and sausage, as well as the growth of Aspergillus versicolor, inhibits the growth of Alternaria solani, Penicillium citrinum and Aspergillus niger, with minimum inhibitory concentrations of 0.02%, 0.08% and 0.08%, respectively[1].
Potassium sorbate (0.05-0.15%) delays or prevents spore germination and growth initiation of Aspergillus parasiticus and Aspergillus flavus strains, slows their hyphal growth, inhibits the growth of Aspergillus sulphureus and Penicillium viridicatum as well as their ability to produce ochratoxin A, and reduces or even blocks the production of aflatoxin B1 by Aspergillus parasiticus and Aspergillus flavus[1].
Potassium sorbate (0.05%) inhibits the growth of Zygosaccharomyces rouxii, Saccharomyces bisporus, Saccharomyces acidifaciens and Saccharomyces pastorianus, and is used in combination with acids[1].
Incorporation of potassium sorbate (≥15%) into sweet potato starch films significantly inhibits the growth of E. coli, but exerts no inhibitory effect on S. aureus[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Danio rerio (4-month-old adults)[2]
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Dosage:0.1 g/L; 1 g/L
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Administration:aqueous exposure; daily water replacement; 14 days
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Result:Decreased levels of intestinal IgG, IL-1β, and TNF-α. Altered core gut microbiota development, with Pelomonas becoming the most abundant genus (accounting for 32.77% of gut microbiota), while Reyranella and Sphingomonas decreased, and Rhizobacter increased. Decreased relative abundance of transcription, energy metabolism, and cancer pathways. Significantly reduced the gut microbiota activity index (AIM).
化学情報
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CAS 番号 24634-61-5
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性状 Solid
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分子量 150.22
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分子式 C6H7KO2
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Color White to off-white
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SMILES
C/C=C/C=C/C([O-])=O.[K+]
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別名
Potassium sorbate; Sorbic acid potassium
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
溶剤 & 溶解度
H2O : 50 mg/mL (332.85 mM; Need ultrasonic)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Liewen MB, et al. Growth and Inhibition of Microorganisms in the Presence of Sorbic Acid: A Review. J Food Prot. 1985;48(4):364-375. [Content Brief]
[2]. Peng Q, et al. Potassium sorbate suppresses intestinal microbial activity and triggers immune regulation in zebrafish (Danio rerio). Food Funct. 2019;10(11):7164-7173. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 6.6569 mL | 33.2845 mL | 66.5690 mL | 166.4226 mL |
| 5 mM | 1.3314 mL | 6.6569 mL | 13.3138 mL | 33.2845 mL | |
| 10 mM | 0.6657 mL | 3.3285 mL | 6.6569 mL | 16.6423 mL | |
| 15 mM | 0.4438 mL | 2.2190 mL | 4.4379 mL | 11.0948 mL | |
| 20 mM | 0.3328 mL | 1.6642 mL | 3.3285 mL | 8.3211 mL | |
| 25 mM | 0.2663 mL | 1.3314 mL | 2.6628 mL | 6.6569 mL | |
| 30 mM | 0.2219 mL | 1.1095 mL | 2.2190 mL | 5.5474 mL | |
| 40 mM | 0.1664 mL | 0.8321 mL | 1.6642 mL | 4.1606 mL | |
| 50 mM | 0.1331 mL | 0.6657 mL | 1.3314 mL | 3.3285 mL | |
| 60 mM | 0.1109 mL | 0.5547 mL | 1.1095 mL | 2.7737 mL | |
| 80 mM | 0.0832 mL | 0.4161 mL | 0.8321 mL | 2.0803 mL | |
| 100 mM | 0.0666 mL | 0.3328 mL | 0.6657 mL | 1.6642 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.