Stigmalactam
Stigmalactam is an aristolactam-type alkaloid extracted from Orophea enterocarpa with anticancer effects. Stigmalactam induces apoptosis via the mitochondrial pathway, with the activation of caspase-3/9, and a decrease in mitochondrial membrane potential (MTP). Stigmalactam exhibits antioxidant activity by decreasing ROS production. Stigmalactam can be used for liver and breast cancer research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 289499-72-5
- 分子式: C18H15NO5
- 分子量:325.32
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
Stigmalactam (24 h) dose-dependently inhibits HepG2, MDA-MB-231 and murine fibroblast NIH3T cells growth with IC50 values of 22.98, 33.23 and 24.44 μM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 289499-72-5
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分子量 325.32
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分子式 C18H15NO5
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SMILES
O=C1NC2=CC3=CC=C(C=C3C4=C2C1=C(OC)C(OC)=C4OC)O
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Structure Classification
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)