TIQ-A
Based on 1 Customer Validation
TIQ-A is a potent TNKS (poly-ART, PARP) inhibitor, with an IC50 of 24 nM for TNKS2. TIQ-A is a potential anti-ischemic agent.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.85%
- CAS 番号: 420849-22-5
- 分子式: C11H7NOS
- 分子量:201.24
-
保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
-
溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
-
Cell Cycle/DNA Damage Compound Library
HY-L004
-
Epigenetics Compound Library
HY-L005
-
Anti-Cancer Compound Library
HY-L025
-
Anti-Aging Compound Library
HY-L034
-
Anti-Cardiovascular Disease Compound Library
HY-L046
-
Anti-Breast Cancer Compound Library
HY-L074
-
Anti-Pancreatic Cancer Compound Library
HY-L077
-
Heterocyclic Compound Library
HY-L138
-
Highly Selective Inhibitors Library
HY-L158
-
Anti-Ovarian Cancer Compound Library
HY-L173
-
Multi-Target Compound Library
HY-L176
-
Bioactive Compound Library Max
HY-L181
-
MCE Bioactive Compound Library
HY-L001V
-
Bioactive Compound Library
HY-L001
-
High-Throughput Bioactive Compound Library
HY-L205
-
MCE Kinase Hinge Binder Fragment Library
HY-L907
生物活性
|
TNKS2 24 nM (IC50) |
PARP2 210 nM (IC50) |
PARP15 230 nM (IC50) |
PARP10 >10 μM (IC50) |
PARP14 >10 μM (IC50) |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
>100 μM
Compound: 1, TIQ-A
|
Inhibition of tankyrase-1 function in human HeLa cells
Inhibition of tankyrase-1 function in human HeLa cells
|
10.1039/C1MD00021G |
化学情報
-
CAS 番号 420849-22-5
-
性状 Solid
-
分子量 201.24
-
分子式 C11H7NOS
-
Color Light green to green
-
SMILES
O=C1NC2=C(C3=C1C=CC=C3)C=CS2
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 125 mg/mL (621.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (276 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.9692 mL | 24.8460 mL | 49.6919 mL | 124.2298 mL |
| 5 mM | 0.9938 mL | 4.9692 mL | 9.9384 mL | 24.8460 mL | |
| 10 mM | 0.4969 mL | 2.4846 mL | 4.9692 mL | 12.4230 mL | |
| 15 mM | 0.3313 mL | 1.6564 mL | 3.3128 mL | 8.2820 mL | |
| 20 mM | 0.2485 mL | 1.2423 mL | 2.4846 mL | 6.2115 mL | |
| 25 mM | 0.1988 mL | 0.9938 mL | 1.9877 mL | 4.9692 mL | |
| 30 mM | 0.1656 mL | 0.8282 mL | 1.6564 mL | 4.1410 mL | |
| 40 mM | 0.1242 mL | 0.6211 mL | 1.2423 mL | 3.1057 mL | |
| 50 mM | 0.0994 mL | 0.4969 mL | 0.9938 mL | 2.4846 mL | |
| 60 mM | 0.0828 mL | 0.4141 mL | 0.8282 mL | 2.0705 mL | |
| 80 mM | 0.0621 mL | 0.3106 mL | 0.6211 mL | 1.5529 mL | |
| 100 mM | 0.0497 mL | 0.2485 mL | 0.4969 mL | 1.2423 mL |
TIQ-A 関連分類
HY-121719 関連分類
Powered by Bioz