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Cat. No.: HY-112541

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21-Hydroxyoligomycin A

21-Hydroxyoligomycin A is a potent inhibitor of K-Ras PM localization with an IC₅₀ value of 4.82 nM. 21-Hydroxyoligomycin A has cytotoxicity and can be isolated from Streptomyces.

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CAS No.: 102042-09-1
화학식: C₄₅H₇₄O₁₂
분자량:807.06

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

21-Hydroxyoligomycin A Chemical Structure

CAS No.: 102042-09-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

21-Hydroxyoligomycin A is a potent inhibitor of K-Ras PM localization with an IC₅₀ value of 4.82 nM. 21-Hydroxyoligomycin A has cytotoxicity and can be isolated from Streptomyces^[1].

All Ras Isoforms :

All Antibiotic Isoforms :

In Vitro

21-Hydroxyoligomycin A is cytotoxic to SW620 and SW620 Ad300 cells with IC₅₀ values of 14.4 and 11.8 μM, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 102042-09-1
분자량 807.06
화학식 C₄₅H₇₄O₁₂
SMILES

C[C@@H]([C@]1([H])OC(/C=C/[C@@H]([C@H]([C@@H](C([C@@H]([C@H]([C@@H]2C)O)C)=O)C)O)C)=O)[C@@](O[C@H]3C[C@H](O)C)(CC[C@@H]3C)O[C@](C[C@H]([C@H](/C=C/C=C\C[C@H]([C@@H]([C@@](O)(C2=O)C)O)C)CC)O)([H])[C@H]1C
Structure Classification
- Antibiotics
- Macrolide Antibiotics
Initial Source
- Microorganisms
Streptomyces cyaneogriseus
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Salim AA, et al. Oligomycins as inhibitors of K-Ras plasma membrane localisation. Org Biomol Chem. 2016 Jan 14;14(2):711-715. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References

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21-Hydroxyoligomycin A

All Ras Isoforms

All Antibiotic Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

21-Hydroxyoligomycin A Related Classifications

HY-112541 Related Classifications