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Cat. No.: HY-N20718

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Agastinol

Agastinol is a naturally sourced caspase-3 inhibitor. Agastinol inhibits the expression of caspase-3 and apoptosis induced by Etoposide (HY-13629) in human leukemia U937 cells. Agastinol can be used in leukemia-related research.

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CAS No.: 413615-33-5
화학식: C₂₇H₂₈O₈
분자량:480.51

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Agastinol Chemical Structure

CAS No.: 413615-33-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
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Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]

Caspase 3

15.2 μg/mL (IC₅₀)

All Caspase Isoforms :

In Vitro

Agastinol (compound 1) inhibits the expression of caspase-3 in human leukemia U937 cells induced by Etoposide (HY-13629), with an IC₅₀ of 15.2 μg/mL^[1]^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 413615-33-5
분자량 480.51
화학식 C₂₇H₂₈O₈
SMILES

C(OC(=O)C1=CC=C(O)C=C1)[C@H]2[C@@H](OC[C@H]2CC3=CC(OC)=C(O)C=C3)C4=CC(OC)=C(O)C=C4
Structure Classification
- Phenylpropanoids
- Lignans
Initial Source
- Plants
- Labiatae
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Zielińska S, et al. Phytochemistry and bioactivity of aromatic and medicinal plants from the genus Agastache (Lamiaceae). Phytochemistry Reviews, 2014, 13: 391-416.

[2]. Lee C, et al. Agastinol and agastenol, novel lignans from Agastache rugosa and their evaluation in an apoptosis inhibition assay. Journal of natural products. 2002 Mar;65(3):414-6. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

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Agastinol

All Caspase Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Agastinol Related Classifications

HY-N20718 Related Classifications