Nudifloramide-d3
Based on 1 Customer Validation
Nudifloramide-d3 (2PY-d3) is the deuterium labeled Nudifloramide. Nudifloramide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Nudifloramide significantly inhibits poly(ADP-ribose) polymerase (PARP-1) activity in vitro.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.43%
- CAS No.: 1207384-48-2
- 화학식: C7H5D3N2O2
- 분자량:155.17
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보관:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
All Endogenous Metabolite Isoforms
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Biological Activity
제품 설명
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
신청
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1207384-48-2
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Unlabeled CAS 701-44-0
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Appearance Solid
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분자량 155.17
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화학식 C7H5D3N2O2
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Color White to off-white
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SMILES
C(N)(=O)C1=CN(C([2H])([2H])[2H])C(=O)C=C1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
용액&용해도
In Vitro:
H2O : 33.33 mg/mL (214.80 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 6.4445 mL | 32.2227 mL | 64.4454 mL | 161.1136 mL |
| 5 mM | 1.2889 mL | 6.4445 mL | 12.8891 mL | 32.2227 mL | |
| 10 mM | 0.6445 mL | 3.2223 mL | 6.4445 mL | 16.1114 mL | |
| 15 mM | 0.4296 mL | 2.1482 mL | 4.2964 mL | 10.7409 mL | |
| 20 mM | 0.3222 mL | 1.6111 mL | 3.2223 mL | 8.0557 mL | |
| 25 mM | 0.2578 mL | 1.2889 mL | 2.5778 mL | 6.4445 mL | |
| 30 mM | 0.2148 mL | 1.0741 mL | 2.1482 mL | 5.3705 mL | |
| 40 mM | 0.1611 mL | 0.8056 mL | 1.6111 mL | 4.0278 mL | |
| 50 mM | 0.1289 mL | 0.6445 mL | 1.2889 mL | 3.2223 mL | |
| 60 mM | 0.1074 mL | 0.5370 mL | 1.0741 mL | 2.6852 mL | |
| 80 mM | 0.0806 mL | 0.4028 mL | 0.8056 mL | 2.0139 mL | |
| 100 mM | 0.0644 mL | 0.3222 mL | 0.6445 mL | 1.6111 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.