Palmitic acid calcium

Cat. No.: HY-N0830A: Data Sheet Handling Instructions
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Palmitic acid calcium is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells. Palmitic acid calcium is used to establish a cell steatosis model.

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CAS No. : 542-42-7

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Other In-stock Forms of Palmitic acid calcium:

Palmitic acid Palmitic acid sodium

Other Forms of Palmitic acid calcium:

Palmitic acid-¹³C sodium In-stock
Palmitic acid-¹³C₁₆ sodium In-stock
Palmitic acid-1,2,3,4-¹³C₄ In-stock
Palmitic acid-¹³C₂ In-stock
Palmitic acid-d₃₁ In-stock
Palmitic acid-1-¹³C In-stock
Palmitic acid-d₂ In-stock
Palmitic acid-d₃ In-stock
Palmitic acid-¹³C₁₆ In-stock
Palmitic acid-d₄ In-stock
Palmitic acid-¹³C In-stock
Palmitic acid In-stock
Palmitic acid sodium In-stock
Palmitic acid-15,15,16,16,16-d₅ Get quote
Palmitic acid-d₂-1 Get quote
Palmitic acid-9,10-d₂ Get quote

100 Publications Citing Use of MCE Palmitic acid calcium

Flow Cytometry

Cell Imaging/Staining

Cell Proliferation/Viability Assay

: Palmitic acid calcium purchased from MedChemExpress. Usage Cited in: Redox Biol. 2025 Feb 3:80:103528. [Abstract]; OVCAR8 and A2780 cells were cultured in fatty acid-free media supplemented with 50 μM AA (arachidonic acid), 50 μM OA (oleic acid), 50 μM EPA (eicosapentaenoic acid), 50 μM PA (Palmitic acid), and 50 μM MA (myristic acid) with the treatment of 10 μM niraparib for 72 h, and the cell viability was determined.

: Palmitic acid calcium purchased from MedChemExpress. Usage Cited in: Autophagy. 2025 Jan;21(1):178-190. [Abstract]; Sqstm1^−/− MEFs reconstituted with vector, flag-SQSTM1 WT, or Flag-SQSTM1^K7R were treated with BSA or Palmitic acid (PA) (500 μM) for 12 h. Cell lysates were mixed with loading buffer containing or not containing DTT were subjected to SDS-PAGE and IB.

: Palmitic acid calcium purchased from MedChemExpress. Usage Cited in: Free Radic Biol Med. 2025 Jan:226:171-184. [Abstract]; Cell viability was assessed using CCK-8 assay in MIN6 cells treated with 33.3 mM glucose and varying concentrations of palmitic acid (PA; 0, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, and 0.8 mM) for 24 h.

: Palmitic acid calcium purchased from MedChemExpress. Usage Cited in: Free Radic Biol Med. 2025 Jan:226:171-184. [Abstract]; FACS plots and quantification of Annexin-V+/PI + population percentage, indicative of apoptotic cells, were analyzed in controls and HGP-treated cells. MIN6 cells with HGP(33.3 mM glucose and 0.3 mM Palmitic acid sodium) for 24 h, cell survival remained around 80 %.

: Palmitic acid calcium purchased from MedChemExpress. Usage Cited in: Free Radic Biol Med. 2025 Jan:226:171-184. [Abstract]; Immunoblot and quantification of p16, p21, and p-γH2A.X in HGP-treated MIN6 cells. The β-actin blot was used as a protein loading control. MIN6 cells treated with high glucose and palmitic acid (HGP; 33.3 mM glucose and 0.3 mM palmitic acid sodium) for 24 h.

: Palmitic acid calcium purchased from MedChemExpress. Usage Cited in: Free Radic Biol Med. 2025 Jan:226:171-184. [Abstract]; Representative images and quantification of SA-β-gal staining in MIN6 cells. MIN6 cells were treated with high glucose and palmitic acid (HGP; 33.3 mM glucose and 0.3 mM Palmitic acid sodium) for 24 h.

: Palmitic acid calcium purchased from MedChemExpress. Usage Cited in: Free Radic Biol Med. 2025 Jan:226:171-184. [Abstract]; Representative images of nuclear morphological changes observed via DAPI staining. MIN6 cells were treated with high glucose and palmitic acid (HGP; 33.3 mM glucose and 0.3 mM Palmitic acid sodium) for 24 h.

: Palmitic acid calcium purchased from MedChemExpress. Usage Cited in: Bioact Mater. 2023 Nov 9:33:85-99.; The expression of NLRP3 and GSDMD was detected in PDLCs treated with palmitic acid (PA) (300 μM; 24 h).

: Palmitic acid calcium purchased from MedChemExpress. Usage Cited in: Cell Discov. 2023 Mar 7;9(1):26. [Abstract]; Palmitic acid (PA; 20 or 100 μM; 24 h) rescues ACOX1-mediated β-catenin inhibition in HCT15 cells (transfected with Flag-ACOX1 plasmid).

: Palmitic acid calcium purchased from MedChemExpress. Usage Cited in: Cell Discov. 2023 Mar 7;9(1):26. [Abstract]; Palmitic acid (PA; 50, 100, 200 μM; 24 h) decreases endogenous β-catenin polyubiquitination in a dose-dependent manner, in HEK293T cells.

: Palmitic acid calcium purchased from MedChemExpress. Usage Cited in: Cell Discov. 2023 Mar 7;9(1):26. [Abstract]; Palmitic acid (PA; 100 μM; 24 h) suppresses the interactions between β-catenin and CK1, GSK3, and β-TrCP in HEK293T cells (transfected with Flag-CK1 and Flag-GSK3β).

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Human Endogenous Metabolite Microbial Metabolite

Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target

Grp78

Human Endogenous Metabolite

In Vitro

Palmitic acid calcium (0.1, 0.25 or 0.5 mM; 12-72 h) increases the mRNA levels of Notch1, 2 and 4 in LX2, Huh7 and MIHA hepatic cell lines^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

Molecular Weight

275.46

Formula

C₁₆H₃₂O₂.1/2Ca

CAS No.

542-42-7

SMILES

CCCCCCCCCCCCCCCC([O-])=O.[Ca+2].[0.5]

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Plants

Animals

Microorganisms

Widespread

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Harada H, et al. Antitumor activity of palmitic acid found as a selective cytotoxic substance in a marine red alga. Anticancer Res. 2002 Sep-Oct;22(5):2587-90. [Content Brief]

[2]. Wen-Jin Ding, et al. Expression of Notch family is altered in non alcoholic fatty liver disease. Mol Med Rep. 2020 Sep;22(3):1702-1708. [Content Brief]