PARP1-IN-45
PARP1-IN-45 (Compound 15) is a PARP1 inhibitor with an IC50 of 17 nM. PARP1-IN-45 effectively stimulates ATPase activity of ABCG2. PARP1-IN-45 can be used for cancers like ovarian cancer research.
For research use only. We do not sell to patients.
- Formula: C26H21N5O4S
- Molecular Weight:499.54
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Protocols
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
PARP1 17 nM (IC50) |
Chemical Information
-
Molecular Weight 499.54
-
Formula C26H21N5O4S
-
SMILES
NC(C1=CC=CC2=C1O/C(C2=O)=C\C3=CC=C(C(N4CCN(CC4)C5=NC6=C(N5)C=CC=C6)=O)S3)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PARP1-IN-45 Related Classifications
HY-178100 Related Classifications
Powered by Bioz