SD-7300
SD-7300 (SC-81490) is an orally active inhibitor of MMP-2, MMP-9, and MMP-13 with Ki values ??of 0.03, 0.01, and 0.03 nM, respectively. SD-7300 can reduce the degradation of extracellular matrix by tumor cells, thereby inhibiting the invasion and metastasis of tumor cells. In addition, SD-7300 is also a dose-dependent inhibitor of mouse corneal angiogenesis and an inhibitor of interleukin-1-induced bovine cartilage degradation. SD-7300 can be used in breast cancer research.
For research use only. We do not sell to patients.
- CAS No.: 748120-89-0
- Formula: C21H30F3N3O7S
- Molecular Weight:525.54
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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MMP-2 0.03 nM (Ki) |
MMP-9 0.01 nM (Ki) |
MMP13 0.03 nM (Ki) |
Chemical Information
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CAS No. 748120-89-0
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Molecular Weight 525.54
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Formula C21H30F3N3O7S
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SMILES
O=C(C1(S(=O)(N2CCC(CC2)OC3=CC=C(C=C3)OC(F)(F)F)=O)CCN(CC1)CCOC)NO
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Synonyms
SC-81490; PF-02881307
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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