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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3517 Results for "
metals
" in MedChemExpress (MCE) Product Catalog:
Products (3517)
3517 Results for "metals" in MCE Product Catalog:
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2-Theoyltrifluoroacetone is a chelating agent and mitochondrial electron transfer chain inhibitor, with a IC50 value of 51.5 μM. 2-Thermoyltrifluoroacetone can chelate with various metal ions and has cytotoxicity and anti-tumor activity, which is expected to play an important role in the treatment of mitochondrial dysfunction related diseases .
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Natural Products Plants Other Families Extract Disease Research Fields Inflammation/Immunology
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4
4 Cited Publications
Cat. No.: HY-D0155
CAS No.: 288574-78-7
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3 Cited Publications
Synonyms: Diethylenetriaminepentaacetic acid; DTPA
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Pentetic acid (Diethylenetriaminepentaacetic acid) is an orally active compound with biodegradability used to construct magnetic adsorbent, which can simultaneously remove heavy metal and dye from complex wastewater. Pentetic acid can form strong metal complexes, which prevents metal ions from catalysing the decomposition of peroxygen chemicals, especially hydrogen peroxide .
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3 Cited Publications
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DMT1 blocker 2 is a direct inhibitor of divalent metal transporter 1 (DMT1), with an IC50 of 0.83 μM. DMT1 blocker 2 can block iron uptake by enterocytes in vivo .
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3 Cited Publications
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DMT1 blocker 1 is an orally active blocker of divalent metal transporter 1 (DMT1) with an IC50 of 0.64 μM. DMT1 blocker 1 inhibits intestinal cell absorption of non-heme iron, thereby alleviating iron overload by blocking the DMT1 transporter. DMT1 blocker 1 demonstrates significant efficacy in rodent models of acute iron hyperabsorption. DMT1 blocker 1 is useful for studying iron overload disorders such as hereditary hemochromatosis and thalassemia .
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3 Cited Publications
Synonyms: Deferoxamine B (Standard); Deferriferrioxamine B (Standard); Deferrioxamine (Standard)
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Reference Standards HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species (ROS) Apoptosis Akt Autophagy
Research Areas:
Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Deferoxamine (Standard) is the analytical standard of Deferoxamine. This product is intended for research and analytical applications. Deferoxamine (Deferoxamine B) is an iron chelator (binds to Fe(III) and many other metal cations), is widely used to reduce iron accumulation and deposition in tissues. Deferoxamine upregulates HIF-1α levels with good antioxidant activity. Deferoxamine also shows anti-proliferative activity, can induce apoptosis and autophagy in cancer cells. Deferoxamine can be used in studies of diabetes, neurodegenerative diseases as well as anti-cancer and anti-COVID-19 .
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2 Cited Publications
Cat. No.: HY-D1746
CAS No.: 162303-59-5
Synonyms: EDTA acetoxymethyl ester; Ethylenediaminetetraacetic acid acetoxymethyl ester
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2
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Dixanthogen is a dimer of xanthate, which forms via the oxidation of xanthate. Dixanthogen can decompose peroxides, which are key radical initiators for the oxidative degradation of polypropylene. Dixanthogen serves as a stabilizer for polypropylene, a pediculicide, and is also used in studies related to metal recovery .
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2 Cited Publications
Cat. No.: HY-W012788
CAS No.: 118-71-8
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2 Cited Publications
Synonyms: CB7; Carrier CB7
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Cyclam is a metal chelator that forms metal complexes with a variety of metal ions. Cyclam metal complexes exhibits anti-HIV (such as AMD3100), nitric oxide (NO) releasing and scavenging (such as Zn(II)-Cyclam and Ru(II)-Cyclam), and SOD mimetic (such as Mn(III)-Cyclam and Zn(II)-Cyclam) activities .
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Thiosemicarbazide is a vitamin B6 antagonist with anti-acne activity. Thiosemicarbazide is also a well-known source in the synthesis of heterocycles, and its derivatives have potential anticancer activity. Thiosemicarbazide (TSC: HL1) reacts with metal salts, urea (U), to prepare Co(II) and Cu(I) metal complexes. Thiosemicarbazide is also used in the fields of media communications and optical storage, and in the spectrophotometric detection of metals .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
