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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10371 Results for "
faecal aromatic compound
" in MedChemExpress (MCE) Product Catalog:
Products (10371)
10371 Results for "faecal aromatic compound" in MCE Product Catalog:
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7 Cited Publications
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αvβ1 integrin-IN-1 (Compound C8) is a potent and selective αvβ1 integrin inhibitor with an IC50 of 0.63 nM. Antifibrotic effects .
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7 Cited Publications
Cat. No.: HY-100445A
Purity: 98.28%
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αvβ1 integrin-IN-1 TFA (Compound C8) is a potent and selective αvβ1 integrin inhibitor with an IC50 of 0.63 nM. Antifibrotic effects .
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7 Cited Publications
Synonyms: R-568 hydrochloride; NPS R-568
Tecalcet Hydrochloride (R 568 Hydrochloride), an orally active calcimimetic compound, allosterically and positively modulates the calcium-sensing receptor (CaSR). Tecalcet Hydrochloride (R 568 Hydrochloride) increases the sensitivity to activation by extracellular Ca 2+ .
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6 Cited Publications
Synonyms: Teijin compound 1 hydrochloride
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CCR2 antagonist 4 hydrochloride (Teijin compound 1 hydrochloride) is a potent and specific CCR2 antagonist, with IC50s of 180 nM for CCR2b. CCR2 antagonist 4 hydrochloride potently inhibits MCP-1-induced chemotaxis with an IC50 of 24 nM .
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6 Cited Publications
Synonyms: Teijin compound 1
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CCR2 antagonist 4 (Teijin compound 1) is a potent and specific CCR2 antagonist, with IC50s of 180 nM for CCR2b. CCR2 antagonist 4 potently inhibits MCP-1-induced chemotaxis with an IC50 of 24 nM .
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6 Cited Publications
Synonyms: 17-Hydroxy-11-dehydrocorticosterone; Kendall's compound E
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6 Cited Publications
Cat. No.: HY-N0748
CAS No.: 39011-91-1
Category:
Other Monoterpenes Paeoniaceae Extract Monophenols Paeonia lactiflora Pall. Terpenoids Phenols Plants
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Triterpenes Terpenoids Plants Disease Research Fields Pulsatilla chinensis (Bunge) Regel Cancer Ranunculaceae Extract
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6 Cited Publications
Cat. No.: HY-17035
CAS No.: 117704-25-3
Category:
Infection Microorganisms Antibiotics Anti-parasitic Disease Research Antibacterial Disease Research Fields Other Antibiotics
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Triterpenes Terpenoids Plants Camellia sinensis (L.) O. Ktze. Disease Research Fields Inflammation/Immunology Theaceae Extract
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6 Cited Publications
Synonyms: PTP1B inhibitor
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PTP1B-IN-1 (Compound 7a) is a small molecule inhibitor of PTP1B with an IC50 value of 1.6 mM. It is often used as the mother core for derivatives of analogues .
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5 Cited Publications
Cat. No.: HY-N0904
CAS No.: 39262-14-1
Synonyms: Ginsenoside compound K; Ginsenoside K
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Panax ginseng C. A. Meyer Triterpenes Terpenoids Plants Disease Research Fields Inflammation/Immunology Araliaceae Extract
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5 Cited Publications
Cat. No.: HY-W011727
CAS No.: 853645-22-4
Synonyms: Pyridoxal phosphate hydrate
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5 Cited Publications
Cat. No.: HY-W011727A
CAS No.: 41468-25-1
Synonyms: Pyridoxal phosphate monohydrate
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5 Cited Publications
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UNC6852 is a PRC2 PROTAC degrader, with a DC50 value of 0.79 μM for EED (HeLa), 0.3 μM for EZH2 (HeLa), and 0.59 μM for SUZ12 (DLBCL). UNC6852 binds to the WD40 aromatic cage of EED and CRL2-VHL, inducing proteasomal degradation of EED, EZH2 and SUZ12. UNC6852 reduces the level of H3K27me3 and exerts antiproliferative effects in cancer cells. UNC6852 can be used in studies related to diffuse large B-cell lymphoma, triple-negative breast cancer and prostate cancer .
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E7820 (ER68203-00), an orally active aromatic sulfonamide derivative, is a molecular glue that induces the targeted degradation of splicing factor RBM39 by recruiting the E3 ubiquitin ligase CUL4-RBX1-DDB1-DCAF15 (CRL4 DCAF15). E7820 is an angiogenesis inhibitor suppressing an expression of integrin alpha2 subunit on endothelium. E7820 inhibits rat aorta angiogenesis with an IC50 of 0.11 μg/ml. E7820 modulates α-1, α-2, α-3, and α-5 integrin mRNA expression. E7820 can be used for the study of acute myeloid leukemia (AML) .
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5 Cited Publications
Synonyms: NITD609; KAE609
Cipargamin (NITD609) is an potent antimalarial compound, with an IC50 of appr 1 nM against P. falciparum.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
