10357 Results for "

dimer-based compound

" in MedChemExpress (MCE) Product Catalog:
Products (10357)

10357 Results for "dimer-based compound" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-136485
CAS No.: 1995893-58-7
Purity:  99.86%
Target:  

FLAP

Research Areas:  

Cancer

FEN1-IN-4 (Compound 2) is a human flap endonuclease-1 (hFEN1) inhibitor .
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3
3 Cited Publications
Cat. No.: HY-N0547
CAS No.: 1063-77-0
Nomilin is a limonoid compound obtained from the extracts of citrus fruits. Nomilin is an anti-obesity and anti-hyperglycemic agent .
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3
3 Cited Publications
Cat. No.: HY-B2116
CAS No.: 526-18-1
Synonyms: Oxaphenamide; 4'-Hydroxysalicylanilide
Target:  

HBV

Research Areas:  

Infection Cancer

Osalmid is a ribonucleotide reductase small subunit M2 (RRM2) targeting compound; suppresses ribonucleotide reductase activity with an IC50 of 8.23 μM.
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3
3 Cited Publications
Cat. No.: HY-126217
CAS No.: 1314796-00-3
Purity:  99.94%
Target:  

Succinate Receptor 1

Research Areas:  

Metabolic Disease

hGPR91 antagonist 1 (Compound 4c) is a potent and selective GPR91 antagonist with an IC50 of 7 nM for human GPR91 .
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3
3 Cited Publications
Cat. No.: HY-139092
CAS No.: 1332184-63-0
Purity:  98.04%
Target:  

Interleukin Related

Research Areas:  

Infection Cancer

IL-4-inhibitor-1 (compound 52) is an IL-4 inhibitor, with an EC50 of 1.81 µM .
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3
3 Cited Publications
Cat. No.: HY-N0661
CAS No.: 556-27-4
Alliin, an orally active sulfoxide compound that can be isolated from garlic, exhibits hypoglycemic, antioxidant, anti-inflammatory and antitumor activities .
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3
3 Cited Publications
Cat. No.: HY-112914
CAS No.: 468747-17-3
Purity:  98.82%
Target:  

mTOR Autophagy

Research Areas:  

Cancer

mTOR inhibitor-1 (Compound C-4) is an ATP-Competitive mTOR inhibitor which can suppress cells proliferation and inducing autophagy .
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3
3 Cited Publications
Cat. No.: HY-111483
CAS No.: 2097416-76-5
Purity:  99.31%
Synonyms: AZD0364
Target:  

ERK

Research Areas:  

Cancer

Tizaterkib (AZD0364) is a potent and selective ERK2 inhibitor extracted from patent WO2017080979A1, compound example 18, has an IC50 of 0.6 nM.
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3
3 Cited Publications
Cat. No.: HY-19762
CAS No.: 1150701-66-8
Synonyms: SCD inhibitor 1
Research Areas:  

Cancer

GSK1940029 (SCD inhibitor 1) is a stearoyl-coa desaturase (SCD) inhibitor extracted from patent WO/2009060053 A1, compound example 16.
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3
3 Cited Publications
Cat. No.: HY-Y0061
CAS No.: 59-48-3
Synonyms: 2-Indolinone
Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.
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3
3 Cited Publications
Cat. No.: HY-111630
CAS No.: 56563-17-8
Purity:  ≥98.0%
Target:  

Topoisomerase

Research Areas:  

Cancer

PluriSIn #2 is a selective transcriptional inhibitor of topoisomerase II α (TOP2A). PluriSIn #2 is a compound that selectively eliminates undifferentiated human pluripotent stem cells (hPSCs) .
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3
3 Cited Publications
Cat. No.: HY-N0132
CAS No.: 94-07-5
Synonyms: Oxedrine
Synephrine (Oxedrine), an alkaloid, is an α-adrenergic and β-adrenergic agonist derived from the Citrus aurantium. Synephrine is a sympathomimetic compound and can be used for weight loss .
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3
3 Cited Publications
Cat. No.: HY-N0132A
CAS No.: 5985-28-4
Synonyms: Oxedrine hydrochloride
Synephrine (Oxedrine) hydrochloride, an alkaloid, is an α-adrenergic and β-adrenergic agonist derived from the Citrus aurantium. Synephrine hydrochloride is a sympathomimetic compound and can be used for weight loss .
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3
3 Cited Publications
Cat. No.: HY-N8253
CAS No.: 20229-56-5
Synonyms: Quercetin 4′-O-glucoside
Spiraeoside, an orally active natural compound, exerts antioxidant activity, inhibits reactive oxygen species (ROS) and malondialdehyde production. Spiraeoside possesses antiallergic, anti-inflammatory and antitumor activities .
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3
3 Cited Publications
Cat. No.: HY-101509
CAS No.: 2095156-13-9
Purity:  99.65%
Target:  

Lipase

Research Areas:  

Metabolic Disease

HSL-IN-1 (compound 24b) is a potent and orally active hormone sensitive lipase (HSL) inhibitor (IC50=2 nM) with a significantly reduced reactive metabolite liability .
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3
3 Cited Publications
Cat. No.: HY-102028
CAS No.: 292168-79-7
Purity:  ≥98.0%
Target:  

Wnt β-catenin

Research Areas:  

Cancer

KY1220 is a compound that destabilizes both β-catenin and Ras, via targeting the Wnt/β-catenin pathway, with an IC50 of 2.1 μM in HEK293 reporter cells .
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3
3 Cited Publications
Cat. No.: HY-138625B
CAS No.: 2414974-55-1
Synonyms: LOX-IN-3 dihydrochloride monohydrate
Target:  

Monoamine Oxidase

Research Areas:  

Cardiovascular Disease Cancer

PXS-5505 (LOX-IN-3 dihydrochloride monohydrate) (Compound 33) is an orally active lysyl oxidase (LOX) inhibitor. PXS-5505 can be used for fibrosis, cancer and angiogenesis research .
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3
3 Cited Publications
Cat. No.: HY-B2114
CAS No.: 6805-41-0
Escin, a natural compound of triterpenoid saponins that can be isolated from horse chestnut (Aesculus hippocastanum) seeds, can be used as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent .
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3
3 Cited Publications
Cat. No.: HY-N0609
CAS No.: 104-55-2
Cinnamaldehyde is a major and a bioactive compound isolated from the leaves of Cinnamomum osmophloeum kaneh. Cinnamaldehyde is a cytokine production inhibitor. Cinnamaldehyde has anti-bacteria, anti-oxidation, and anti-inflammatory properties .
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3
3 Cited Publications
Cat. No.: HY-108570
CAS No.: 479413-70-2
Purity:  ≥98.0%
Target:  

Epoxide Hydrolase

Research Areas:  

Inflammation/Immunology

AUDA (compound 43) is a potent soluble epoxide hydrolase (sEH) inhibitor with IC50s of 18 and 69 nM for the mouse and human sEH, respectively . AUDA has anti-inflammatory activity .
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