156 Results for "

hypoglycemic

" in MedChemExpress (MCE) Product Catalog:
Products (156)

156 Results for "hypoglycemic" in MCE Product Catalog:

Cat. No.: HY-N19984
Synonyms: Yacon extract
Category:  

Extract

Target:  

Bacterial

Smallanthus sonchifolius extract (Yacon extract) is an extract of yacon (Smallanthus sonchifolius) that has antibacterial, hypoglycemic, anti-obesity, anti-cancer, and cholesterol-lowering activities.
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Cat. No.: HY-W093416
CAS No.: 25055-82-7
Target:  

TRP Channel

Research Areas:  

Metabolic Disease

3,3-Azo-1-butanol is an orally active hypoglycemic agent. 3,3-Azo-1-butanol increases liver weight and induces fat infiltration .
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Cat. No.: HY-118523
CAS No.: 74772-68-2
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

AL-321 is an insulin sensitizer. AL-321 exhibits significant hypoglycemic and hypolipidemic activities in insulin resistance models. AL-321 can be used in the research of hereditary obesity-related diabetes .
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Cat. No.: HY-N19811
CAS No.: 194851-33-7
Eleuthoside B is a naphthyl gentiobioside identified from the bulbs of Eleutherine americana. Eleuthoside B has an IC50 >1.00 mM against α-glucosidase, and it is not the main contributor to the antidiabetic (hypoglycemic) activity exhibited by the plant extract .
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Cat. No.: HY-124461
CAS No.: 537-05-3
Target:  

Drug Intermediate

Research Areas:  

Metabolic Disease

Guanidine is a guanidine-containing compound with hypoglycemic activity, which can serve as a Drug Intermediate for synthesizing various guanidine-skeleton derivatives. Guanidine hydrochloride induces hypoglycemia in rabbits and causes symptoms identical to those of parathyroidectomy-induced tetany in rabbits. Guanicaine and its derivatives are applicable to diabetes-related research .
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Cat. No.: HY-165385
CAS No.: 83901-40-0
AZ-DF 265 is a hypoglycemic agent that stimulates insulin release. AZ-DF-265 inhibits ATP-sensitive potassium channels, activates voltage-dependent calcium channels, allows calcium ion influx, and ultimately promotes insulin secretion. AZ-DF 265 can be used in diabetes-related research .
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Cat. No.: HY-183205
CAS No.: 1628744-37-5
Target:  

Somatostatin Receptor

Research Areas:  

Metabolic Disease

SSTR5 antagonist 7 is an orally active SSTR5 antagonist, with an IC50 of 6.2 nM against hSSTR5 and an IC50 of 25 nM against mouse-derived SSTR5. SSTR5 antagonist 7 exerts a sustained hypoglycemic effect. SSTR5 antagonist 7 can be used for the research of diabetes .
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Cat. No.: HY-N21949A
CAS No.: 15592-33-3
Synonyms: Methyl glucosinolate potassium
Glucocapparin (Methyl glucosinolate) potassium is a glucosinolate compound. Glucocapparin potassium can be isolated from plants of the Brassicaceae and Capparaceae families. Glucocapparin potassium possesses phytochemical defense (insect-repellent and antibacterial), hypoglycemic and antioxidant activities, and the isothiocyanate substances produced by its hydrolysis exhibit certain anticancer effects. Glucocapparin potassium can be used in studies related to cancer, inflammation and hyperglycemia .
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Cat. No.: HY-N17985
CAS No.: 119742-55-1
Kalopanaxsaponin H is an hederagenin glycoside (saponin) with no hypoglycemic activity upon intraperitoneal injection. Kalopanaxsaponin H can be metabolized by human intestinal bacteria into Kalopanaxsaponin I, Kalopanaxsaponin A, hederagenin 3-O-α-L-arabinopyranoside and hederagenin, among which Kalopanaxsaponin I and hederagenin are the main metabolites. Kalopanaxsaponin H is isolated from the stem bark of Kalopanax pictus and is used in diabetes-related research .
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Cat. No.: HY-N21978
CAS No.: 247031-40-9
Steppogenin 4'-O-β-D-glucoside is a flavanone glycoside hypoglycemic agent that can be isolated from the root bark of Morus alba L. Steppogenin 4'-O-β-D-glucoside reduces the fasting blood glucose level of alloxan-induced diabetic mice. Steppogenin 4'-O-β-D-glucoside can be used in studies related to diabetes .
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Cat. No.: HY-16397AS
Synonyms: Phenethylbiguanide-d5 hydrochloride
Phenformin-d5 (Phenethylbiguanide-d5) hydrochloride is the deuterium labeled Phenformin hydrochloride. Phenformin hydrochloride is an orally active biguanide hypoglycemic agent. Phenformin hydrochloride inhibits mitochondrial respiratory chain complex I, leading to an increased AMP/ATP ratio, activation of AMPK, and subsequent inhibition of the mTOR pathway, thereby suppressing cell proliferation, inducing apoptosis and autophagy. Phenformin hydrochloride inhibits cancer stem cells (CSCs) and possesses potent antitumor potential.
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Cat. No.: HY-N0416R
CAS No.: 6199-67-3
Cucurbitacin B (Standard) is the analytical standard of Cucurbitacin B. This product is intended for research and analytical applications. Cucurbitacin B belongs to a class of highly oxidized tetracyclic triterpenoids and is oral active. Cucurbitacin B inhibits tumor cell growth, migration and invasion and cycle arrest, but induces cell apoptosis. Cucurbitacin B has potent anti-inflammatory, antioxidant, antiviral, hypoglycemic, hepatoprotective, neuroprotective activity .
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Cat. No.: HY-N12543
CAS No.: 27539-32-8
Peonidin 3-rutinoside is an anthocyanin. Peonidin 3-rutinoside is isolated from Lonicera caerulea berries, blackcurrant ethanol extracts, sweet cherry extracts, Berberis boliviana Lechler fruits, blue wheat, sweet and sour cherries, and strawberries. Anthocyanins exert multiple effects, including free radical scavenging activity, anti-inflammatory effects, anticancer effects, and hypoglycemic effects .
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Cat. No.: HY-N20390
Scrophularia ningpoensis extract is an orally effective hypoglycemic and antioxidant agent. Scrophularia ningpoensis extract reduces fasting blood glucose levels, increases plasma insulin levels, ameliorates impaired antioxidant status, scavenges free radicals, inhibits lipid peroxidation, and decreases elevated serum creatinine and serum urea levels. Scrophularia ningpoensis extract reduces the risk of developing diabetic complications. Scrophularia ningpoensis extract is applicable to diabetes-related research .
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Cat. No.: HY-N7241
CAS No.: 94978-16-2
Saudin, derived from Clutia lanceolata, is a hypoglycemic compound that significantly enhances glucose-triggered insulin release from murine pancreatic islets. It belongs to a group of new diterpenoids with a distinct tetracyclic core, suggesting potential as a therapeutic agent for diabetes treatment. Proposed biosynthetic pathways outline alternative cyclization routes from a common precursor, with Lanceolide P (16) identified as a promising lead compound for further development in managing diabetes .
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Cat. No.: HY-105789
CAS No.: 538-03-4
Target:  

HIV Bacterial

Research Areas:  

Infection Inflammation/Immunology

Oxophenarsine hydrochloride is an anti-syphilitic agent, and also has non-classical applications including treating chronic discoid lupus erythematosus, inhibiting HIV-1 protein synthesis, and prolonging the duration of insulin action . Oxophenarsine hydrochloride forms an unstable insulin complex via sulfhydryl groups or free amino groups, thereby prolonging the hypoglycemic effect of insulin. Oxophenarsine hydrochloride inhibits HIV-1-specific protein synthesis and virus production .
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Cat. No.: HY-163005
CAS No.: 3018963-27-1
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

α-Glucosidase-IN-43 (compound AS14) is an α-glucosidase inhibitor (IC50: 4.32 μM) with acute hypoglycemic activity. α-Glucosidase-IN-43 exhibits safety and in vivo efficacy, is nontoxic to normal mouse fibroblasts, and is able to rescue streptozotocin (HY-13753)-induced diabetic rats. α-Glucosidase-IN-43 can be used to study postprandial hyperglycemia in diabetic patients .
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Cat. No.: HY-173503
CAS No.: 1598439-44-1
Target:  

GLUT

Research Areas:  

Metabolic Disease

DS-1150b is an orally active GLUT4 activator. DS-1150b has the activity of activating GLUT4 transport and can promote the translocation of GLUT4 to the cell membrane in skeletal muscle cells. DS-1150b has shown hypoglycemic effects in the Zucker obese rat model and can be used in the study of type 2 diabetes mellitus (T2DM) .
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Cat. No.: HY-N2413
CAS No.: 60546-10-3
Gomisin D is an orally active lignan that binds to PDGFRβ with a Kd of 10 μM. By targeting PDGFRβ to regulate signaling pathways, Gomisin D inhibits the activation and proliferation of hepatic stellate cells and promotes their apoptosis, thereby ameliorating hepatic fibrosis. Gomisin D exhibits multiple activities such as photoprotection, antimelanogenesis, antioxidant effects, and hypoglycemic activity. Gomisin D can be used in studies related to diabetes, Alzheimer's disease, and hepatic fibrosis .
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Cat. No.: HY-16397AR
CAS No.: 834-28-6
Synonyms: Phenethylbiguanide hydrochloride (Standard)
Phenformin (Phenethylbiguanide) hydrochloride (Standard) is the analytical standard of Phenformin hydrochloride (HY-16397). This product is intended for research and analytical applications. Phenformin hydrochloride (Phenethylbiguanide) is an orally active biguanide hypoglycemic agent. Phenformin hydrochloride inhibits mitochondrial respiratory chain complex I, leading to an increased AMP/ATP ratio, activation of AMPK, and subsequent inhibition of the mTOR pathway, thereby suppressing cell proliferation, inducing apoptosis and autophagy. Phenformin hydrochloride inhibits cancer stem cells (CSCs) and possesses potent antitumor potential.
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