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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2243 Results for "
Nicotinic acid amide-13C,15N
" in MedChemExpress (MCE) Product Catalog:
Products (2243)
2243 Results for "Nicotinic acid amide-13C,15N" in MCE Product Catalog:
99
99 Publications Verification
Synonyms: Niacinamide; Nicotinic acid amide
51
Research Areas:
Methyllycaconitine (MLA) citrate is a blood-brain barrier-permeable antagonist of α7 nicotinic acetylcholine receptor (α7nAChR) with an IC50 of 2 nM. Methyllycaconitine citrate inhibits Aβ25-35-induced autophagy by restoring the mTOR pathway, and prevents reactive oxygen species (ROS) production, microglial activation, reduced dopamine uptake, loss of dopaminergic terminals and catecholamine secretion. Methyllycaconitine citrate induces hippocampal glutamate efflux, enhances long-term potentiation, and improves memory acquisition. Methyllycaconitine citrate can be used in research related to Alzheimer's disease, cerebral palsy, Parkinson's disease and schizophrenia .
51
51 Cited Publications
Synonyms: MK-933; CD-5024; K-237
43
43 Cited Publications
Cat. No.: HY-P0014
CAS No.: 204656-20-2
Target:
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
43
43 Cited Publications
Cat. No.: HY-P0014B
Target:
Research Areas:
33
17
17 Cited Publications
Synonyms: DMXB-A; DMBX-anabaseine
Target:
Research Areas:
GTS-21 dihydrochloride is a selective alpha7 nicotinic acetylcholine receptor (α7-nAChR) agonist with anti inflammatory and cognition enhancing activities. GTS-21 dihydrochloride is also a α4β2 (Ki=20 nM for humanα4β2) and 5-HT3A receptor (IC50=3.1 μM) antagonist .
15
15 Cited Publications
Target:
Research Areas:
PNU-282987 is a potent α7 nicotinic acetylcholine receptor (nAChR) agonist with an EC50 of 154 nM. PNU-282987 is also a functional antagonist of the 5-HT3 receptor with an IC50 of 4541 nM. PNU-282987 can be used for the research of central and peripheral nervous systems .
15
Category:
Target:
14
14 Cited Publications
Cat. No.: HY-W016319
CAS No.: 138-15-8
Target:
Research Areas:
13
Category:
Microorganisms Ketones, Aldehydes, Acids Disease markers Metabolic Disease Nervous System Disorder Endogenous metabolite Disease Research Fields
Target:
13
13 Cited Publications
Synonyms: Nicotinic acid hydrochloride; Vitamin B3 hydrochloride
Category:
Alkaloids Ketones, Aldehydes, Acids Pyridine Alkaloids Metabolic Disease Endogenous metabolite Disease Research Fields Cancer
Target:
12
12 Cited Publications
Synonyms: MC-207,110 dihydrochloride; Phe-Arg-β-naphthylamide dihydrochloride
11
11 Cited Publications
Synonyms: Quinurenic acid; Fibrostop 2
Category:
Alkaloids Human Gut Microbiota Metabolites Neurological Disease Quinoline Alkaloids Endogenous metabolite Disease Research Fields Endocrinology
Target:
11
Category:
Alkaloids Quinoline Alkaloids Endogenous metabolite Disease Research Fields Inflammation/Immunology
Target:
10
10 Cited Publications
Cat. No.: HY-N0473A
CAS No.: 69847-45-6
Target:
9
9 Cited Publications
Cat. No.: HY-P1264
CAS No.: 11032-79-4
Target:
Research Areas:
8
8 Cited Publications
MK-6892 is a potent, selective, and full agonist for the high affinity nicotinic acid (NA) receptor GPR109A. Ki and GTPγS EC50 of MK-6892 on the Human GPR109A is 4 nM and 16 nM, respectively.
7
7
7 Cited Publications
Synonyms: methyl 1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxylate hydrobromide
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
