88 Results for "

DHA

" in MedChemExpress (MCE) Product Catalog:
Products (88)

88 Results for "DHA" in MCE Product Catalog:

50
50 Publications Verification
Referencia número: HY-B2167
No. CAS: 6217-54-5
Synonyms: DHA; Cervonic acid
Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk.
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50
50 Publications Verification
Referencia número: HY-B0573
No. CAS: 318-98-9
Propranolol hydrochloride is a nonselective and BBB-permeableβ-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively. Propranolol hydrochloride inhibits [ 3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM. Propranolol hydrochloride is used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy .
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50
50 Publications Verification
Referencia número: HY-B0573B
No. CAS: 525-66-6
Propranolol is a nonselective and BBB-permeable β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively . Propranolol inhibits [ 3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM . Propranolol is used for the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy .
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6
6 Cited Publications
Referencia número: HY-116429
No. CAS: 1268720-28-0
Pureza:  99.00%
Áreas de investigación:  

Inflammation/Immunology

Maresin 1, produced by human Mφs from endogenous docosahexaenoic acid (DHA) and a specialized proresolving mediator, stimulates intracellular [Ca 2+] and secretion. Maresin 1 possesses anti-inflammatory activity .
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5
5 Cited Publications
Referencia número: HY-121636
No. CAS: 810668-37-2
Pureza:  99.90%
Synonyms: RvD2
Target:  

TRP Channel

Resolvin D2 is a metabolite of docosahexaenoic acid (DHA), with anti-inflammatory, anti-infective activities. Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis. Resolvin D2 is a remarkably potent inhibitor of TRPV1 (IC50 = 0.1 nM) and TRPA1 (IC50 = 2 nM) in primary sensory neurons .
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3
3 Cited Publications
Referencia número: HY-P1607
No. CAS: 1414-45-5
Target:  

Bacterial Antibiotic

Áreas de investigación:  

Infection Inflammation/Immunology

Nisin is a bacteriocin produced by a group of Gram-positive bacteria that belongs to Lactococcus and Streptococcus species. Nisin has antibacterial and anti-inflammatory activity .
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1
1 Cited Publications
Referencia número: HY-Y0335
No. CAS: 96-26-4
Synonyms: Dihydroxyacetone
1,3-Dihydroxyacetone (DHA), the main active ingredient in sunless tanning skin-care preparations and an important precursor for the synthesis of various fine chemicals, is produced on an industrial scale by microbial fermentation of glycerol (HY-B1659) in Gluconobacter oxydans. 1,3-Dihydroxyacetone is also used for synthesis of new biodegradable polymers by combining with lactic acid (HY-B2227) .
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1
1 Cited Publications
Referencia número: HY-130289
No. CAS: 90906-40-4
Synonyms: 4-Hydroxy docosahexaenoic acid; (±)4-HDoHE
Target:  

PPAR

Áreas de investigación:  

Metabolic Disease Inflammation/Immunology

(±)4-HDHA (4-Hydroxy docosahexaenoic acid) is an autoxidation product of Docosahexaenoic acid (HY-B2167) (DHA). (±)4-HDHA is a PPARγ agonist, antidiabetic and anti-inflammatory agent .
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1
1 Cited Publications
Referencia número: HY-W011120
No. CAS: 84494-72-4
Target:  

Endogenous Metabolite

Áreas de investigación:  

Metabolic Disease

Ethyl cis-4,7,10,13,16,19-Docosahexaenoate, the ethyl ester of Docosahexaenoate (DHA), is enriched in the ethyl ester fraction by the selective alcoholysis of fatty acid ethyl esters originating from tuna oil with lauryl alcohol.
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1
1 Cited Publications
Referencia número: HY-165781
No. CAS: 218608-43-6
Synonyms: C22:6 Ceramide
Target:  

Drug Derivative

Áreas de investigación:  

Metabolic Disease

DHA Ceramide (C22:6 Ceramide) is an ester product.
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Referencia número: HY-113131
No. CAS: 57-04-5
Pureza:  99.90%
Synonyms: DHAP
Dihydroxyacetone phosphate (DHPA), a derivative of Dihydroxyacetone (DHA), is an important intermediate that participates in key pathways including glycolysis, lipid biosynthesis, and the plant Calvin cycle. Dihydroxyacetone phosphate can be used as a substrate and metabolic marker in biochemical research .
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Referencia número: HY-B2167R
No. CAS: 6217-54-5
Synonyms: DHA (Standard); Cervonic acid (Standard)
Docosahexaenoic acid (Standard) is the analytical standard of Docosahexaenoic acid. This product is intended for research and analytical applications. Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk. In Vitro: Docosahexaenoic acid (DHA) is essential for the growth and functional development of the brain in infants. DHA is also required for maintenance of normal brain function in adults. The inclusion of plentiful DHA in the diet improves learning ability and memory . DHA is an essential requirement in every step of brain development like neural cell proliferation, migration, differentiation, synaptogenesis. The multiple double bonds and unique structure allow DHA to impart special membrane characteristics for effective cell signaling. Many development disorders like dyslexia, autism spectrum disorder, attention deficit hyperactivity disorder, schizophrenia etc. are causally related to decreased level of DHA . DHA is a potent RXR ligand inducing robust RXR activation already at low micro molar concentrations. The EC50 for RXRα activation by DHA is about 5-10 μM fatty acid . In Vivo: Docosahexaenoic acid administration over 10 weeks significantly reduces the number of reference memory errors, without affecting the number of working memory errors, and significantly increases the docosahexaenoic acid content and the docosahexaenoic acid/arachidonic acid ratio in both the hippocampus and the cerebral cortex . DHA treatment exerts neuroprotective actions on an experimental mouse model of PD. There is a decrease tendency in brain lipid oxidation of MPTP mice but it does not significantly .
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Referencia número: HY-P3466
No. CAS: 137061-46-2
Target:  

Bacterial Fungal

Áreas de investigación:  

Infection Inflammation/Immunology

Nisin Z is an antimicrobial and anti-inflammatory peptide. Nisin Z is effective against Gram-positive bacteria and fungi, such as C. albicans .
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Referencia número: HY-113131A
Pureza:  99.90%
Synonyms: DHAP hemimagnesium hydrate
Dihydroxyacetone phosphate (DHPA) hemimagnesium hydrate, a derivative of Dihydroxyacetone (DHA), is an important intermediate that participates in key pathways including glycolysis, lipid biosynthesis, and the plant Calvin cycle. Dihydroxyacetone phosphate hemimagnesium hydrate can be used as a substrate and metabolic marker in biochemical research .
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Referencia número: HY-107343
No. CAS: 81926-94-5
Pureza:  96.22%
Synonyms: Ethyl docosahexaenoate
Target:  

COX

Áreas de investigación:  

Neurological Disease Metabolic Disease

Docosahexaenoic acid ethyl ester (Ethyl docosahexaenoate) is a 90% concentrated ethyl ester of docosahexaenoic acid manufactured from the microalgal oil. Docosahexaenoic acid ethyl ester enhances 6-hydroxydopamine-induced neuronal damage by induction of lipid peroxidation in mouse striatum. Docosahexaenoic acid (DHA) is a key component of the cell membrane, and its peroxidation is inducible due to the double-bond chemical structure. Docosahexaenoic acid has neuroprotective effects .
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Referencia número: HY-B2167S
No. CAS: 1197205-71-2
Synonyms: DHA-d5; Cervonic acid-d5
Docosahexaenoic acid-d5 is the deuterium labeled Docosahexaenoic Acid. Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk.
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Referencia número: HY-Y1422I
No. CAS: 9001-62-1
Áreas de investigación:  

Others

Lipase, Pseudomonas fluorescens (Immobilized) is an immobilized biocatalyst derived from Pseudomonas fluorescens. Lipase, Pseudomonas fluorescens (Immobilized) efficiently catalyzes the hydrolysis, esterification and transesterification of triacylglycerols in solvent-free systems, and is particularly suitable for biodiesel production from soybean oil and selective modification of oils rich in EPA and DHA. Lipase, Pseudomonas fluorescens (Immobilized) exhibits optimal activity at pH 8.5 and 45°C, and retains residual activity after repeated cycles of use. Lipase, Pseudomonas fluorescens (Immobilized) is activated by Ca 2+, but inhibited by Co 2+, Ni 2+, Fe 3+, Fe 2+ and EDTA .
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Referencia número: HY-101541
No. CAS: 2566-90-7
Pureza:  ≥95.0%
Synonyms: Methyl docosahexaenoate; all cis-DHA methyl ester
Target:  

Drug Intermediate

Áreas de investigación:  

Neurological Disease

Docosahexaenoic Acid methyl ester is a methylated docosahexaenoic acid analog which can be intercalated into membrane phospholipids without being oxidized or hydrolyzed.
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Referencia número: HY-B0573S1
No. CAS: 344298-99-3
Propranolol-d7 (ring-d7) is the deuterium labeled Propranolol hydrochloride. Propranolol hydrochloride is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively . Propranolol hydrochloride inhibits [3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM . Propranolol hydrochloride is used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy .
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Referencia número: HY-141469
No. CAS: 65919-53-1
Synonyms: HPA; Heneicosapentaenoic acid methyl ester
Category:  

Animals Lipids

6,9,12,15,18-Heneicosapentaenoic acid (HPA) is a ∆5 desaturase inhibitor. 6,9,12,15,18-Heneicosapentaenoic acid serves as a weak substrate for Prostaglandin H synthase and 5-lipoxygenase, yet it inactivates Prostaglandin H synthase at a rate comparable to that of AA, EPA and DHA. 6,9,12,15,18-Heneicosapentaenoic acid is a weak inducer of Aacyl-CoA oxidase. 6,9,12,15,18-Heneicosapentaenoic acid incorporates into phospholipids and triacylglycerols in cell culture. 6,9,12,15,18-Heneicosapentaenoic acid can be used in research related to liver cancer .
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