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Fats

" in MedChemExpress (MCE) Product Catalog:

By Targets:	11β-HSD (1) 5-HT Receptor (2) Acetyl-CoA Carboxylase (3) ACSL Family (2) Acyltransferase (5) Adenosine Deaminase (1) Adenosine Receptor (1) Adrenergic Receptor (22) Akt (8) Amino Acid Derivatives (1) AMPK (17) Amylin Receptor (6) Anaplastic lymphoma kinase (ALK) (1) Androgen Receptor (4) Angiotensin-converting Enzyme (ACE) (1) Anion Exchangers (1) Antibiotic (4) Apoptosis (47) Aryl Hydrocarbon Receptor (3) Atg8/LC3 (2) AUTACs (1) Autophagy (10) Bacterial (15) Bcl-2 Family (3) Beta-lactamase (1) Biochemical Assay Reagents (37) Calcium Channel (3) CaMK (1) Cannabinoid Receptor (2) Carnitine Palmitoyltransferase (CPT) (3) Caspase (5) CDK (3) CETP (1) CGRP Receptor (2) Cholecystokinin Receptor (1) COX (3) Cytochrome P450 (7) Dihydrofolate reductase (DHFR) (1) Dipeptidyl Peptidase (1) Dopamine Receptor (1) Drug Derivative (5) Drug Intermediate (2) Drug Metabolite (5) Endogenous Metabolite (164) Environmental Pollutants (24) ERK (2) Estrogen Receptor/ERR (7) Exosomes (1) FABP (2) Fat Mass and Obesity-associated Protein (FTO) (19) FATP (1) Fatty Acid Synthase (FASN) (2) Ferroptosis (2) Fluorescent Dye (6) Free Fatty Acid Receptor (1) Fungal (5) FXR (6) G protein-coupled Bile Acid Receptor 1 (1) GABA Receptor (1) Gap Junction Protein (7) GCGR (2) GLP Receptor (6) Glucocorticoid Receptor (3) Glucokinase (3) GLUT (1) Glutathione Peroxidase (1) Glycosidase (3) Glycosyltransferase (1) GPR109A (1) GSK-3 (6) Guanylate Cyclase (2) HBV (2) HDAC (7) Hedgehog (1) Herbicide (1) HIF/HIF Prolyl-Hydroxylase (2) Histamine Receptor (2) Histone Demethylase (2) HIV (6) HSP (4) IDE (1) Influenza Virus (2) Insecticide (4) Insulin Receptor (1) Interleukin Related (12) Isotope-Labeled Compounds (64) JAK (2) JNK (2) Keap1-Nrf2 (3) Lactate Dehydrogenase (1) LDLR (2) Lipase (4) Liposome (7) MAGL (1) MCHR1 (GPR24) (2) MDM-2/p53 (3) Melanocortin Receptor (1) MetAP (2) Mitochondrial Metabolism (7) Mitophagy (6) MMP (5) Monoamine Oxidase (1) mTOR (3) NF-κB (21) NOD-like Receptor (NLR) (4) Notch (6) Nuclear Hormone Receptor 4A/NR4A (1) Organoid (5) Orphan GPCR (1) P-glycoprotein (2) p38 MAPK (9) p62 (2) Parasite (2) PARP (1) PCSK9 (3) PEPCK (1) PGC-1α (19) PGE synthase (1) Phosphodiesterase (PDE) (1) Phospholipase (2) PI3K (3) Piezo Channel (1) PKA (15) Potassium Channel (4) PPAR (25) Prostaglandin Receptor (6) PROTACs (1) Pyroptosis (1) RAR/RXR (2) Ras (2) Reactive Oxygen Species (ROS) (14) Reference Standards (52) ROR (1) Ser/Thr Kinase (1) Sirtuin (6) Small Interfering RNA (siRNA) (8) Smo (1) SOD (4) Sodium Channel (1) Somatostatin Receptor (1) STAT (2) Stearoyl-CoA Desaturase (SCD) (6) TGF-beta/Smad (1) TGF-β Receptor (2) Thyroid Hormone Receptor (3) TNF Receptor (6) Toll-like Receptor (TLR) (3) Topoisomerase (1) Trace Amine-associated Receptor (TAAR) (5) TRP Channel (2) Tyrosinase (2) VEGFR (1) Wnt (4) Xanthine Oxidase (2) YTHDF (1) α-synuclein (1) β-catenin (4)
By Research Areas:	Cancer (104) Cardiovascular Disease (52) Endocrinology (30) Infection (37) Inflammation/Immunology (76) Metabolic Disease (272) Neurological Disease (43)
Oligonucleotides:	Solvents (1) Liposome (2) Rat Pre-designed siRNA Sets (2) Emulsifiers (3) Mouse Pre-designed siRNA Sets (2) Phospholipids (2) Human Pre-designed siRNA Sets (4) Surfactants (1) Cholesterol (1) siRNAs (8) pH Modifiers (1)

456

Inhibitors & Agonists

Screening Libraries

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

MCE Kits

Inhibitory Antibodies

117

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Isotope-Labeled Compounds

Oligonucleotides

GMP Molecules

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-131370B

Intralipid 20% 4 Publications Verification	Biochemical Assay Reagents	Cancer
Intralipid 20% is a safe fat emulsion that can be used as a nutritional supplement. Intralipid 20% effectively inhibits the opening of the mitochondrial permeability transition pore, effectively protecting the heart from ischaemia-reperfusion injury and has some potential to modulate the innate immune response .

HY-Y0781

Pyruvic acid 15+ Cited Publications Acetylformic acid	Environmental Pollutants Endogenous Metabolite	Others
Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats.

HY-N2041

Myristic acid 5+ Cited Publications	Environmental Pollutants Endogenous Metabolite Bacterial NF-κB	Infection Inflammation/Immunology
Myristic acid is an orally active saturated 14-carbon fatty acid found in most animal and plant fats, especially milk fat coconut oil, palm oil and nutmeg oil. Myristic acid exerts anti-inflammatory activity through the NF-κB pathway. Myristic acid has antibacterial, anti-inflammatory and analgesic properties .

HY-W042416

N,N-Dimethylacetamide 1 Publications Verification DMAc	NF-κB	Neurological Disease Metabolic Disease Inflammation/Immunology
N,N-Dimethylacetamide (DMAc) is an organic solvent with blood-brain transmissibility and an FDA-approved drug excipient. N, N-dimethylacetamide exerts anti-inflammatory activity by inhibiting the NF-κB signaling pathway. N, N-dimethylacetamide can be used in studies of weight gain caused by a high-fat diet and neuroinflammation in Alzheimer's disease .

HY-P10745

Petrelintide ZP8396	Amylin Receptor	Metabolic Disease
Petrelintide (ZP8396) is a dual amylin and calcitonin receptor agonist (DACRA) Petrelintide elicits a selective reduction in high-fat diet intake in diet-induced obese (DIO) rats, which is accompanied by a loss of fat mass and preservation of lean mass during weight reduction. Petrelintide can be utilized in diabetes research .

HY-D0213

Sudan Black B 1 Publications Verification	Environmental Pollutants Fluorescent Dye	Others
Sudan Black B, a fat-soluble diazo dye, is a histochemical stain. Sudan Black B can be used for staining of neutral triglycerides and lipids .

HY-Y1110I

Magnesium chloride, for insect cell culture, 97% Magnogene, for insect cell culture, 97%	Environmental Pollutants Biochemical Assay Reagents	Infection
Magnesium chloride, for insect cell culture, 97% is an orally active inorganic mineral salt. Magnesium chloride combined with Potassium chloride (HY-Y0537E) increases the fat body glycogen, protein, total lipids and haemolymph protein and trehalose in the silkworm, Bombyx mori L .

HY-P10745A

Petrelintide acetate ZP8396 acetate	Amylin Receptor	Metabolic Disease
Perelintide (ZP8396) acetate is a dual amylin and calcitonin receptor agonist (DACRA). Perelintide acetate elicits a selective reduction in high-fat diet intake in diet-induced obese (DIO) rats, which is accompanied by a loss of fat mass and preservation of lean mass during weight reduction. Perelintide acetate can be utilized in diabetes research .

HY-145632

Pemvidutide ALT-801	GLP Receptor GCGR	Metabolic Disease
Pemvidutide (ALT-801) is a GLP-1R/GCGR dual agonist, shows striking reductions in body weight, liver fat and serum lipids. Pemvidutide can be used in non-alcoholic steatohepatitis (NASH) and obesity research .

HY-101900

Nile Blue A sulfate Nile blue sulfate	Fluorescent Dye	Others
Nile Blue A (Nile blue sulfate) is used to differentiate melanins and lipofuscins. It is also useful for staining fats and preparation of an amperometric glucose sensor .

HY-15671

GKA50	Glucokinase	Metabolic Disease
GKA50 is a potent glucokinase activator (EC₅₀=33 nM at 5 mM glucose). GKA50 stimulates insulin release from mouse islets of Langerhans. GKA50 is a glucose-like activator of beta-cell metabolism in rodent and human islets and a Ca ²⁺-dependent modulator of insulin secretion. GKA50 shows significant glucose lowering in high fat fed female rats .

HY-151226

Glyceryl monostearate GMS	Environmental Pollutants Liposome	Others
Glyceryl monostearate (GMS) is a type of monoglyceride. Glyceryl monostearateGlyceryl monostearate can serve as a core lipid material for constructing solid lipid nanoparticles in the field of drug delivery. Glyceryl monostearate can be used as a gelling agent to structure liquid vegetable oils into semi-solid oleogels, so as to replace animal fat in meat products .

HY-101832

SBC-110736 1 Publications Verification	PCSK9	Cardiovascular Disease Metabolic Disease
SBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor extracted from patent WO2014150395A1 .

HY-N7515

Pinocembrin chalcone 2',4',6'-Trihydroxychalcone	Bacterial AMPK	Infection Metabolic Disease Inflammation/Immunology
Pinocembrin chalcone (2',4',6'-Trihydroxychalcone) is an antibacterial compound from Helichrysum Trilineatum. Pinocembrin chalcone facilitates AMP-activated protein kinase (AMPK) activation, improves glucose tolerance, increases muscle FAO and reduces fat accumulation in the liver and skeletal muscles in high-fat diet-induced (HFD) diabetic mice. Pinocembrin chalcone is promising for research of gastric ulcers and diabetes .

HY-Y1242

Choline hydroxide (44% in water)	Environmental Pollutants Biochemical Assay Reagents	Others
Choline hydroxide is a Choline hydrogen oxidized derivative and a strong organic base, can be used as the standard alkaline to adjust the pH of the medium. Choline is an orally active nutrient, serves as an important component of lecithin and sphingomyelin, promotes fat metabolism .

HY-138207

N-Oleoyl-L-phenylalanine	Mitochondrial Metabolism Drug Metabolite	Inflammation/Immunology
N-Oleoyl-L-phenylalanine is a long-chain N-acyl-L-phenylalanine and also a mitochondrial uncoupler. N-Oleoyl-L-phenylalanine uncouples UCP1-independent respiration in mitochondria, thereby helping to regulate glucose homeostasis. As an endogenous metabolite, the level of N-Oleoyl-L-phenylalanine increases in patients with ulcerative colitis after a high-fat diet. N-Oleoyl-L-phenylalanine can be used in studies related to ulcerative colitis .

HY-W088066

Trisodium phosphate (dodecahydrate)	Bacterial	Infection
Trisodium phosphate dodecahydrate is an Antibacterial agent. Trisodium phosphate dodecahydrate reduces the counts of Escherichia coli O157:H7 and Salmonella typhimurium attached to the surfaces of beef fat and fascia. Trisodium phosphate dodecahydrate modulates the growth parameters of Listeria monocytogenes in vitro: low concentrations shorten the lag phase and increase the maximum growth rate, while high concentrations prolong the lag phase and decrease the maximum growth rate. Trisodium phosphate dodecahydrate is used in poultry processing .

HY-B1788S

Taurocholic acid-d4 sodium 1 Publications Verification N-Choloyltaurine-d4 sodium	Endogenous Metabolite	Inflammation/Immunology
Taurocholic acid-d₄ (sodium) is the deuterium labeled Taurocholic acid. Taurocholic acid (N-Choloyltaurine) is a bile acid involved in the emulsification of fats.

HY-P3704

Enterostatin (rat)	Endogenous Metabolite	Metabolic Disease
Enterostatin (rat), an orally active activation peptide of procolipase, selectively reduces fat intake. Enterostatin (rat) reduces serum cholesterol levels by way of a CCK1 receptor-dependent mechanism .

HY-D1353

LipidGreen 2	Fluorescent Dye	Others
LipidGreen 2 is a second generation small molecule probe for lipid imaging. LipidGreen 2 has a better fluorescence signal compared with the previous LipidGreen, and selectively stains neutral lipids in cells and fat deposits in live zebrafish .

HY-P2932

Cholecystokinin 1 Publications Verification Cholecystokinin-33(human); CCK-33(human)	Cholecystokinin Receptor	Metabolic Disease
Cholecystokinin is a peptide hormone. Cholecystokinin, as a hunger suppressant, inhibits food intake and stimulates the digestion of fat and protein. Cholecystokinin can be used for the research of gastrointestinal system .

HY-W009417

Cedryl acetate	Environmental Pollutants Glycosidase	Metabolic Disease
Cedryl acetate is an orally active α-glucosidase inhibitor with an IC₅₀ of 94 μM against yeast α-glucosidase. Cedryl acetate reduces high-fat diet-induced body weight gain, visceral fat pad weight, adipocyte hypertrophy, hepatic lipid accumulation, glucose intolerance, insulin resistance and gluconeogenesis. Cedryl acetate can be used in the research of obesity and obesity-related metabolic syndrome .

HY-P5275

Tripeptide-41 CG-Lipoxyn	NF-κB Histone Demethylase	Metabolic Disease
Tripeptide-41 (CG-Lipoxyn) is a signal peptide. Tripeptide-41 activates the NF-kB signaling pathway, inhibits the expression of C/EBP and increases cAMP. Tripeptide-41 is an important intracellular signaling factor that causes lipolysis by promoting the hydrolysis of lipids into triglycerides. Tripeptide-41 can be used in cosmetics that targets fat accumulation .

HY-116538

(10E,12Z)-Octadeca-10,12-dienoic acid 1 Publications Verification trans-10,cis-12 CLA2	Endogenous Metabolite PPAR NF-κB Stearoyl-CoA Desaturase (SCD) Lipase	Metabolic Disease Inflammation/Immunology Cancer
(10E,12Z)-Octadeca-10,12-dienoic acid (trans-10,cis-12 CLA2) is an orally active PPARα activator and inhibits adipocyte differentiation. (10E,12Z)-Octadeca-10,12-dienoic acid and its downstream metabolites have various antioxidant and antitumor activities. (10E,12Z)-Octadeca-10,12-dienoic acid can induce proinflammatory cytokines and chemokines, which would lead to decreased adipogenesis and insulin resistance in adipose tissue. (10E,12Z)-Octadeca-10,12-dienoic acid can affect many aspects of milk fat synthesis. (10E,12Z)-Octadeca-10,12-dienoic acid reduces expression of lipogenic enzymes and inhibits the desaturation of fatty acids. (10E,12Z)-Octadeca-10,12-dienoic acid can reduce lipoprotein lipase (LPL) activity in cultured 3T3-L1 adipocytes and enhance triacylglycerol release from these cells. (10E,12Z)-Octadeca-10,12-dienoic acid decreases the expression of hepatic stearoyl-CoA desatyrase mRNA in mice. (10E,12Z)-Octadeca-10,12-dienoic acid is associated with changes in mucosal NF-κB and Cyclin D1 protein levels in mice .

HY-E70528

HRV-3C protease fuses with GST	Biochemical Assay Reagents	Others
HRV-3C protease fuses with GST is a recombinant protease fused with HRV-3C protease and GST, which recognizes the LEVLFQGP polypeptide sequence. HRV-3C protease fuses with GST precisely cleaves between glutamine and glycine-proline residues to remove fusion tags from target proteins. HRV-3C protease fuses with GST exhibits cleavage activity both in vitro in silkworm fat body lysates and in vivo in silkworm larval fat bodies, and achieves functional expression in E. coli and silkworm-baculovirus expression systems. HRV-3C protease fuses with GST can be applied to recombinant protein-related research .

HY-17462

Adrenosterone (+)-Adrenosterone	Androgen Receptor Endogenous Metabolite	Endocrinology Cancer
Adrenosterone ((+)-Adrenosterone) is a competitive hydroxysteroid (11-beta) dehydrogenase 1 (HSD11β1) inhibitor. Adrenosterone is a steroid hormone with weak androgenic effect. Adrenosterone is a dietary supplement that can decrease fat and increase muscle mass. Adrenosterone acts as a suppressor of metastatic progression of human cancer cells .

HY-145612

Sudan red 7B	Biochemical Assay Reagents	Others
Sudan red 7B is a red non-fluorescent stain that can be used to stain fat bodies .

HY-Y0781S

Pyruvic acid-13C sodium Acetylformic acid-13C sodium	Endogenous Metabolite	Others
Pyruvic acid- ¹³C (sodium) is the ¹³C-labeled Pyruvic acid. Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats.

HY-W012865

Tartronic acid	Carnitine Palmitoyltransferase (CPT) Endogenous Metabolite FABP PPAR	Metabolic Disease
Tartronic acid, a dicarboxylic acid derive, is an inhibitor of the transformation of carbohydrates into fat under fat-deficient diet conditions. Tartronic acid promotes 3T3-L1 adipocyte differentiation by increasing the protein expression of FABP-4, PPARγ and SREBP-1. Tartronic acid promotes de novo lipogenesis and inhibits CPT-1β by upregulating acetyl-CoA and malonyl-CoA. Tartronic acid promotes weight gain and induces adipocyte hypertrophy in epididymal white adipose tissue and lipid accumulation in the livers of high-fat diet induced obese mice. Tartronic acid can be used for lipid metabolic disease research .

HY-Y0781S1

Pyruvic acid-13C Acetylformic acid-¹³C	Endogenous Metabolite	Others
Pyruvic acid- ¹³C is the ¹³C labeled Pyruvic acid . Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats .

HY-Y0781R

Pyruvic acid (Standard) Acetylformic acid (Standard)	Reference Standards Endogenous Metabolite	Others
Pyruvic acid (Standard) is the analytical standard of Pyruvic acid. This product is intended for research and analytical applications. Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats.

HY-138843A

FTO-IN-1 TFA 1 Publications Verification	Fat Mass and Obesity-associated Protein (FTO)	Metabolic Disease Cancer
FTO-IN-1 TFA is a fat mass and obesity-associated enzyme (FTO) inhibitor extracted from patent WO2018157843A1, compound 32, with an IC₅₀ of <1 μM. FTO-IN-1 TFA can be used for the research of cancer .

HY-N0324F

Cholic acid-Biotin	Fluorescent Dye	Metabolic Disease
Cholic acid-Biotin is a biotin-labeled Cholic acid (HY-N0324). Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid has orally activity .

HY-135737

Dicaprylyl carbonate 1 Publications Verification Dioctyl carbonate	Others	Others
Dicaprylyl carbonate, a solid, plant-derived fat, is a dry emollient. Dicaprylyl carbonate has excellent dermatological compatibility and a comprehensive performance profile, such as solubilizing and dispersing ability for sun-care filters .

HY-Y1422B

Lipase (MS grade) 1 Publications Verification	Endogenous Metabolite	Metabolic Disease
Lipase (MS grade) catalyzes the hydrolysis of triacylglycerols to release long-chain fatty acids in a site-specific manner. Lipase (MS grade) is involved in a variety of biological processes, from fat metabolism to cell signaling and inflammation, and can be used to study diseases such as pancreatic insufficiency, celiac disease and cystic fibrosis .

HY-149453

MCUF-651	Guanylate Cyclase	Cardiovascular Disease
MCUF-651 is an orally active guanylyl cyclase A receptor (GC-A) positive allosteric modulator (PAM) (K_D: 397 nM ). MCUF-651 binds to GC-A and selectively enhances the binding of atrial natriuretic peptide (ANP) to GC-A. MCUF-651 enhances ANP-mediated cGMP generation in human cardiac, renal, and fat cells. MCUF-651 inhibits cardiomyocyte hypertrophy .

HY-145632A

Pemvidutide TFA ALT-801 TFA	GLP Receptor GCGR	Metabolic Disease
Pemvidutide (ALT-801) TFA is a GLP-1R/GCGR dual agonist, shows striking reductions in body weight, liver fat and serum lipids. Pemvidutide TFA can be used in non-alcoholic steatohepatitis (NASH) and obesity research .

HY-N2041R

Myristic acid (Standard)	Reference Standards Endogenous Metabolite NF-κB Bacterial	Infection Inflammation/Immunology
Myristic acid (Standard) is the analytical standard of Myristic acid. This product is intended for research and analytical applications. Myristic acid is an orally active saturated 14-carbon fatty acid found in most animal and plant fats, especially milk fat coconut oil, palm oil and nutmeg oil. Myristic acid exerts anti-inflammatory activity through the NF-κB pathway. Myristic acid has antibacterial, anti-inflammatory and analgesic properties .

HY-P3570

Adipokinetic hormone II (Locusta migratoria) Lom-AKH-II	Endogenous Metabolite	Metabolic Disease
Adipokinetic hormone II (Locusta migratoria) (Lom-AKH-II) is a insect adipokinetic hormone (AKH), enhances fat body cAMP levels in vitro. Insect adipokinetic hormones (AKHs) controls flight-directed mobilization of carbohydrate and lipid from fat body stores, which depends on AKH receptor(s) coupling to cAMP formation and glycogen phosphorylase activation via the stimulatory guanine nucleotide-binding protein (Gs) .

HY-172241

Tapencarium RZL-012; Utenpanium chloride	Ser/Thr Kinase	Metabolic Disease
Tapencarium (RZL-012) is a serine/threonine kinase inhibitor. Tapencarium can reduce subcutaneous fat volume. Tapencarium is promising for research of fat-related disorders such as Dercum’s disease and aesthetic applications .

HY-138843

FTO-IN-1	Fat Mass and Obesity-associated Protein (FTO)	Metabolic Disease Cancer
FTO-IN-1 is a fat mass and obesity-associated enzyme (FTO) inhibitor extracted from patent WO2018157843A1, compound 32, with an IC₅₀ of <1 μM. FTO-IN-1 can be used for the research of cancer .

HY-113383

2-Hydroxyvaleric acid	Endogenous Metabolite Lactate Dehydrogenase Biochemical Assay Reagents	Metabolic Disease Endocrinology
2-Hydroxyvaleric acid is a medium chain α-hydroxy fatty acid. 2-Hydroxyvaleric acid is an activator in fat metabolism of palmitic acid-1-C ¹⁴. 2-hydroxyvaleric acid is also used as a staining agent for measuring tissue-specific Lactate dehydrogenase activity and elevated levels of 2-hydroxyvaleric acid induces lactic acidosis .

HY-B1788S1

Taurocholic acid-d4 1 Publications Verification N-Choloyltaurine-d₄	Endogenous Metabolite	Inflammation/Immunology
Taurocholic acid-d₄ is deuterium labeled Taurocholic acid. Taurocholic acid (N-Choloyltaurine) is a bile acid involved in the emulsification of fats.

HY-P3572

Adipokinetic hormone I (Locusta migratoria) Lom-AKH-I	Endogenous Metabolite	Endocrinology
Adipokinetic hormone I (Locusta migratoria) (Lom-AKH-I) is a insect adipokinetic hormone (AKH), enhances fat body cAMP levels in vitro. Insect adipokinetic hormones (AKHs) controls flight-directed mobilization of carbohydrate and lipid from fat body stores, which depends on AKH receptor(s) coupling to cAMP formation and glycogen phosphorylase activation via the stimulatory guanine nucleotide-binding protein (Gs) .

HY-W051298

Distearin Stearic diglyceride	Biochemical Assay Reagents	Metabolic Disease
Distearin is a diacylglycerol containing stearic acid at two positions. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils .

HY-134577

Clorprenaline	Adrenergic Receptor	Endocrinology
Clorprenaline is a potent agonist of β2-adrenergic. Clorprenaline promotes animal muscular mass growth and decreases fat accumulation. Clorprenaline is a potential new lean meat-boosting feed additive .

HY-RS04762

FAT3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
FAT3 Human Pre-designed siRNA Set A contains three designed siRNAs for FAT3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FAT3 Human Pre-designed siRNA Set A FAT3 Human Pre-designed siRNA Set A

HY-P1067

Enterostatin(human,mouse,rat)	Endogenous Metabolite	Metabolic Disease
Enterostatin, human, mouse, rat is a pentapeptide that reduces fat intake.

HY-145238

FTO-IN-6	Fat Mass and Obesity-associated Protein (FTO)	Others
FTO-IN-6 is a selective fat mass and obesity associated protein (FTO) inhibitor.

HY-139821

FTO-IN-5	Fat Mass and Obesity-associated Protein (FTO)	Neurological Disease Cancer
FTO-IN-5 is a potent and selective inhibitor of fat mass obesity-associated protein (FTO).

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0511

Biotin 25+ Cited Publications Vitamin B7; Vitamin H; D-Biotin	Structural Classification Immune System Disorder Microorganisms other families Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Metabolic Disease Plants Endogenous metabolite Disease Research Fields Source Classification	Environmental Pollutants Endogenous Metabolite
Biotin, vitamin B7 and serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. Biotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids .

HY-N0324

Cholic acid 15+ Cited Publications	Human Gut Microbiota Metabolites Microorganisms Other disease Classification of Application Fields Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields Steroids Source Classification	Endogenous Metabolite
Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid is orally active .

HY-N0378

D-Mannitol 10+ Cited Publications Mannitol; Mannite	Structural Classification Natural Products other families Classification of Application Fields Metabolic Disease Plants Endogenous metabolite Disease Research Fields Sweeteners Source Classification Food Research	Environmental Pollutants Endogenous Metabolite Apoptosis PGC-1α PKA Adrenergic Receptor
D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β₃-adrenergic receptor (β₃-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells . D-Mannitol is commonly used to maintain osmotic pressure between the plant cytoplasm and the culture medium and protect cells when the cell wall is weakened or even removed .

HY-123033A

Nicotinamide riboside chloride 20+ Cited Publications	Alkaloids Animals Neurological Disease Classification of Application Fields Anti-aging Pyridine Alkaloids Metabolic Disease Disease Research Fields Source Classification	Sirtuin Endogenous Metabolite
Nicotinamide riboside Chloride, an orally active NAD ⁺ precursor, increases NAD ⁺ levels and activates SIRT1 and SIRT3. Nicotinamide riboside Chloride is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities . Nicotinamide riboside Chloride reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease .

HY-Y0781

Pyruvic acid 15+ Cited Publications Acetylformic acid	Structural Classification Classification of Application Fields Endocrine diseases Endogenous metabolite Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Disease markers Other Diseases Nervous System Disorder Disease Research Fields Cardiovascular System Disorder Source Classification	Environmental Pollutants Endogenous Metabolite
Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats.

HY-N2041

Myristic acid 5+ Cited Publications	Infection Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Environmental Pollutants Endogenous Metabolite Bacterial NF-κB
Myristic acid is an orally active saturated 14-carbon fatty acid found in most animal and plant fats, especially milk fat coconut oil, palm oil and nutmeg oil. Myristic acid exerts anti-inflammatory activity through the NF-κB pathway. Myristic acid has antibacterial, anti-inflammatory and analgesic properties .

HY-B2219

Stearic acid 20+ Cited Publications	Structural Classification Immune System Disorder Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Environmental Pollutants Endogenous Metabolite Apoptosis
Stearic acid is an orally active long-chain dietary saturated fatty acid that can significantly reduce visceral fat by inducing apoptosis of preadipocytes. Stearic acid can be used in the study of cardiovascular and metabolic diseases .

HY-N0145

Puerarin 25+ Cited Publications	Structural Classification Flavonoids Pueraria edulis Pampan. Classification of Application Fields Leguminosae Phenols Polyphenols Plants Disease Research Fields Isoflavones Source Classification Cancer	5-HT Receptor
Puerarin is an isoflavone extracted from Pueraria root and is a 5-HT2C receptor antagonist. Puerarin inhibits the dorsal motor nucleus of the vagus (DMV)-vagus nerve pathway, which in turn leads to decreased fat absorption .

HY-B0234

Estrone 5+ Cited Publications E1; Oestrone	Monophenols Microorganisms Classification of Application Fields Phenols Endogenous metabolite Disease Research Fields Steroids Source Classification Cancer	Estrogen Receptor/ERR Endogenous Metabolite
Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells .

HY-I0400

N-Acetylneuraminic acid 5 Publications Verification NANA; Lactaminic acid	Cardiovascular Disease Microorganisms Classification of Application Fields Endogenous metabolite Disease Research Fields Saccharides Monosaccharides Source Classification	Tyrosinase Ras Influenza Virus Endogenous Metabolite
N-Acetylneuraminic acid (NANA; Lactaminic acid), a nonphenolic structure, is the predominant form of sialic from Collocalia esculenta. N-Acetylneuraminic acid plays a biological role in myocardial injury, melanoma and viral or bacterial infection. N-Acetylneuraminic acid inhibits melanogenesis by reducing tyrosinase activity and triggers myocardial injury in vitro and in vivo by activation of the Rho/Rho-associated signaling pathway through binding to RhoA and Cdc42. N-Acetylneuraminic acid may prevent high fat diet (HFD)-induced inflammation and oxidative stress, thereby prevents hyperlipidemia-associated inflammation and oxidative stress. N-Acetylneuraminic acid is promising for research in the field of melanoma, coronary artery, obesity-related diseases and hyperlipidemia .

HY-N1420

Rhamnose 1 Publications Verification L-Rhamnose	Structural Classification Classification of Application Fields Plants Endogenous metabolite Sweeteners Monosaccharides Food Research Microorganisms other families Disease Research Fields Saccharides Source Classification Cancer	Environmental Pollutants Endogenous Metabolite PKA MMP Interleukin Related
Rhamnose (L-Rhamnose ) is an orally active deoxysugar. Rhamnose can inhibit levels of pro-inflammatory interleukin and matrix metalloproteinases (MMPs) in skin aging models. Rhamnose can promote the phosphorylation levels of PKA substrates and HSL in SVF-derived adipocytes, stimulating PKA signaling. Rhamnose can act against obesity in mice by stimulating fat dopamine receptors and inducing thermogenesis. Rhamnose shows anti-aging effects. Rhamnose monohydrate can be used in the study of Ehrlich’s solid tumors and sarcomas .

HY-N0404

Sinigrin 4 Publications Verification Allyl-glucosinolate; 2-Propenyl-glucosinolate	Structural Classification Alkaloids Cruciferous vegetables Classification of Application Fields Other Alkaloids Metabolic Disease Glucosinolates Plants Brassicaceae Disease Research Fields Source Classification	p38 MAPK AMPK Bacterial Fungal Interleukin Related PPAR CDK PI3K Akt mTOR Apoptosis Reactive Oxygen Species (ROS)
Sinigrin (Allyl-glucosinolate) is an orally active glucosinolate found in cruciferous plants. Sinigrin possesses multiple activities such as anti-cancer, antibacterial, antifungal, anti-inflammatory, antioxidant, and inhibition of fat synthesis. Sinigrin can be used in the research of tumors, inflammatory, and metabolic diseases .

HY-N8518

Malabaricone C 3 Publications Verification	Classification of Application Fields Phenols Polyphenols Metabolic Disease Myristicaceae Plants Myristica fragrans Houtt. Disease Research Fields Source Classification	Phospholipase p38 MAPK Apoptosis NF-κB
Malabaricone C is an orally active and noncompetitive sphingomyelin synthase (SMS) inhibitor with IC₅₀ values of 3 μM and 1.5 μM for SMS 1 and SMS 2, respectively. Malabaricone C reduces body weight gain, improves glucose tolerance, and decreases lipid accumulation in the liver, showing significant prevention of high fat diet-induced fatty liver in mice. Malabaricone C has anti-inflammatory effects, which is found in the fruits of Myristica cinnamomea King. Malabaricone C is promising for research of obesity and immunological disorders caused due to hyper-activation of T-cells .

HY-N0324A

Cholic acid sodium 15+ Cited Publications Sodium cholate	Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Steroids Source Classification	Endogenous Metabolite
Cholic acid sodium is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid sodium is orally active .

HY-B1320

Meclofenamic acid sodium 5+ Cited Publications Meclofenamate sodium	Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification Cancer	Gap Junction Protein Endogenous Metabolite Fat Mass and Obesity-associated Protein (FTO)
Meclofenamic acid (Meclofenamate) sodium is a non-steroidal anti-inflammatory agent (NSAID). Meclofenamic acid sodium is a non-selective gap-junction blocker and a highly selective inhibitor of fat - and obesity-related enzyme (FTO). Meclofenamic acid sodium has anti-inflammatory and antitumor activities .

HY-117275

Meclofenamic acid 5+ Cited Publications Meclofenamate	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Fat Mass and Obesity-associated Protein (FTO) Potassium Channel Gap Junction Protein Endogenous Metabolite
Meclofenamic acid (Meclofenamate) is a non-steroidal anti-inflammatory agent. Meclofenamic acid is a highly selective FTO (fat mass and obesity-associated) enzyme inhibitor. Meclofenamic acid competes with FTO binding for the m(6)A-containing nucleic acid. Meclofenamic acid is a non-selective gap-junction blocker. Meclofenamic acid inhibits hKv2.1 and hKv1.1, with IC₅₀ values of 56.0 and 155.9 μM, respectively .

HY-N6769

Radicicol 4 Publications Verification Monorden	Antifungal Classification of Application Fields Marine natural products Anti-parasitic Disease Research Infection Microorganisms Macrolide Antibiotics Antibiotics Phenols Polyphenols Marine microorganism Disease Research Fields Source Classification	HSP Bacterial Antibiotic Parasite
Radicicol is an inhibitor of Hsp90 with an IC₅₀ value < 1 μM, and leads to proteasomal degradation . Radicicol exhibits inhibition on PDK with IC₅₀s of 230 μM (PDK1) and 400 μM (PDK3). Radicicol is an antifungal and antimalarial antibiotic, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB . Radicicol is also an inhibitor of fat mass and obesity-associated protein (FTO), with an IC₅₀ value of 16.04 μM .

HY-113422

Tetrahydrocorticosterone	Structural Classification Endogenous metabolite Steroids Source Classification	Endogenous Metabolite Glucocorticoid Receptor
Tetrahydrocorticosterone is a glucocorticoid. One of its active forms, 5α-Tetrahydrocorticosterone (HY-113364), exerts its effects by binding to the GC receptor and inhibiting inflammatory processes. Tetrahydrocorticosterone is naturally synthesized by the adrenal glands and plays a key role in regulating the metabolism of carbohydrates, proteins and fats .

HY-N9914

D-Psicose D-Allulose	Human Gut Microbiota Metabolites Endogenous metabolite Source Classification	p38 MAPK NF-κB
D-psicose is an orally active rare sugar. D-psicose inhibits p38-MAPK phosphorylation and MCP-1 expression. D-psicose inhibits the AGEs/RAGE/NF-κB pathway. D-psicose protects pancreatic β-islets, improves hyperglycemia and high-fat diet-induced non-alcoholic fatty liver disease .

HY-B0987

Ascorbyl palmitate 3 Publications Verification L-Ascorbic acid 6-hexadecanoate; 6-O-Palmitoyl-L-ascorbic acid	Structural Classification Natural Products Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification Cancer	Environmental Pollutants Reactive Oxygen Species (ROS) Endogenous Metabolite Apoptosis Bcl-2 Family Caspase Calcium Channel NOD-like Receptor (NLR) Sodium Channel
Ascorbyl palmitate is an orally active ester formed from ascorbic acid and palmitic acid, used as an antioxidant and food additive. Ascorbyl palmitate in preventing fat and oil oxidation is more efficient than Butylated hydroxyanisole (HY-B1066) and Butylated hydroxytoluene (HY-Y0172). Ascorbyl palmitate mitigates inhibition of collagen synthesis by select calcium and sodium channel blockers. Ascorbyl palmitate induces Apoptosis in human umbilical vein endothelial cells (HUVECs). Ascorbyl palmitate ameliorates inflammatory diseases by inhibition of NLRP3 inflammasome .

HY-W013061

Propane-1,2,3-triyl tripalmitate	Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Propane-1,2,3-triyl tripalmitate is a saturated fat. Propane-1,2,3-triyl tripalmitate enhances the lymphatic transport of Glycerol tristearate (HY-127035) .

HY-N0898A

(-)-Catechin 4 Publications Verification (-)-Cianidanol; (-)-Catechuic acid	Flavonoids other families Classification of Application Fields Flavanols Phenols Polyphenols Plants Disease Research Fields Source Classification Cancer	COX
(-)-Catechin is Catechin's one kind of different structure. Catechin inhibitory enzyme-1 (COX-1), IC₅₀ of 1.4 μM. (-)-Catechin promotes hBM-MSC adipose cell differentiation, increases fat cell differentiation, and PPARγ level .

HY-N7072

Grape seed extract 2 Publications Verification	Natural Products Classification of Application Fields Vitis vinifera cv. Zalema Metabolic Disease Plants Vitaceae Disease Research Fields Inflammation/Immunology Source Classification	Apoptosis
Grape seed extract is a natural product, with anti-inflammatory and anti-proliferative effects. Grape seed extract shows inhibitory activity on the fat-metabolizing enzymes pancreatic lipase and lipoprotein lipase. Grape seed extract induces apoptotic in human colorectal cancer cells .

HY-B0234R

Estrone (Standard) 5+ Cited Publications E1(Standard); Oestrone (Standard)	Structural Classification Monophenols Microorganisms Classification of Application Fields Phenols Endogenous metabolite Disease Research Fields Steroids Source Classification Cancer	Reference Standards Estrogen Receptor/ERR Endogenous Metabolite
Estrone (Standard) is the analytical standard of Estrone. This product is intended for research and analytical applications. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells .

HY-123033

Nicotinamide riboside	Natural Products Human Gut Microbiota Metabolites Microorganisms Animals Neurological Disease Classification of Application Fields Anti-aging Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Sirtuin Endogenous Metabolite
Nicotinamide riboside, an orally active NAD ⁺ precursor, increases NAD ⁺ levels and activates SIRT1 and SIRT3. Nicotinamide riboside is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities . Nicotinamide riboside reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease .

HY-N1420A

Rhamnose monohydrate 1 Publications Verification L-Rhamnose monohydrate	Microorganisms other families Classification of Application Fields Plants Disease Research Fields Saccharides Monosaccharides Source Classification Cancer	Endogenous Metabolite MMP Interleukin Related PKA
Rhamnose monohydrate (L-Rhamnose monohydrate) is an orally active deoxysugar. Rhamnose monohydrate can inhibit levels of pro-inflammatory interleukin and matrix metalloproteinases (MMPs) in skin aging models. Rhamnose can promote the phosphorylation levels of PKA substrates and HSL in SVF-derived adipocytes, stimulating PKA signaling. Rhamnose monohydrate can act against obesity in mice by stimulating fat dopamine receptors and inducing thermogenesis. Rhamnose monohydrate shows anti-aging effects. Rhamnose monohydrate can be used in the study of Ehrlich’s solid tumors and sarcomas .

HY-W014901

Bisphenol F BPF; 4,4'-Dihydroxydiphenylmethane	Classification of Application Fields Orchidaceae Galeola faberi Rolfe Phenols Polyphenols Metabolic Disease Plants Disease Research Fields Source Classification	Reactive Oxygen Species (ROS) Akt GSK-3 Apoptosis
Bisphenol F is an orally active endocrine disruptor. Bisphenol F promotes ROS generation, upregulates p-AKT/p-GSK3β, and induces Apoptosis. Bisphenol F interferes with glucose metabolism, affects neurodevelopment and reproductive function. Bisphenol F reduces social novelty preference in mouse offspring. Bisphenol F can be used in bone, blood, and fat-related studies. Bisphenol F is used as a substitute for Bisphenol A (HY-18260) .

HY-N0378R

D-Mannitol (Standard) 10+ Cited Publications Mannitol(Standard); Mannite (Standard)	Structural Classification Natural Products Microorganisms other families Classification of Application Fields Metabolic Disease Plants Endogenous metabolite Disease Research Fields Sweeteners Source Classification Food Research	Reference Standards Endogenous Metabolite Apoptosis PGC-1α Adrenergic Receptor PKA
D-Mannitol (Standard) is the analytical standard of D-Mannitol (HY-N0378). This product is intended for research and analytical applications. D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β₃-adrenergic receptor (β₃-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells . D-Mannitol is commonly used to maintain osmotic pressure between the plant cytoplasm and the culture medium and protect cells when the cell wall is weakened or even removed .

HY-N4137

Tormentic acid 2 Publications Verification	Cardiovascular Disease Triterpenes Classification of Application Fields Terpenoids Rosaceae Plants Disease Research Fields Rosa rugosa Thunb. Source Classification	Others
Tormentic acid, a triterpene isolated from Rosa rugosa, exerts anti-inflammatory, antihyperlipidemic, and anti-atherogenic properties .

HY-W096638A

Glycerophosphocholine (S)-Glycerolphosphocholine	Structural Classification Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Endogenous Metabolite
Glycerophosphocholine ((S)-Glycerolphosphocholine) is an orally active metabolite that crosses the blood-brain barrier. Glycerophosphocholine acts as a precursor of acetylcholine, a specific marker for phosphatidylcholine breakdown, a major water-soluble storage form of choline, and an intermediate in phosphatidylcholine metabolism. Glycerophosphocholine is specifically elevated in the cerebrospinal fluid of Alzheimer's disease models, and it also promotes growth hormone secretion and fat oxidation. Glycerophosphocholine is also a potential biomarker for breast cancer .

HY-W012974

3-Aminoisobutyric acid β-Aminoisobutyric acid; BAIBA	Cardiovascular Disease Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
3-Aminoisobutyric acid (β-Aminoisobutyric acid) has anti-inflammatory and antioxidant effects. 3-Aminoisobutyric acid increases the expression of brown adipocyte-specific genes in white adipose tissue and fatty acid β-oxidation in hepatocytes. 3-Aminoisobutyric acid attenuates insulin resistance and inflammation induced by palmitate or a high fat diet via an AMPK-PPARδ-dependent pathway in mice. 3-Aminoisobutyric acid is a catabolic metabolite of thymine and valine in skeletal muscle .

HY-N2181

Acetylshikonin 3 Publications Verification	Quinones Classification of Application Fields Phenols Polyphenols Plants Lithospermum erythrorhizon Sieb. et Zucc. Naphthalene Quinones Boraginaceae Inflammation/Immunology Disease Research Fields Source Classification	Cytochrome P450 Apoptosis Bacterial Autophagy
Acetylshikonin is an oral active anti-cancer, anti-inflammatory, antioxidant, anti-fertility, antibacterial, and neuroprotective agent. Acetylshikonin is a inhibitor of acetylcholinase (AChE) (IC₅₀=34.6 μM) and nonselective cytochrome P450. Acetylshikonin can induce Apoptosis and Autophagy in cancer cells. Acetylshikonin regulates blood glucose, liver fat metabolism, and renal fibrosis, and is used in the study of diabetes, diabetic nephropathy (DN), obesity, and nonalcoholic fatty liver disease (NAFLD) .

HY-N3686

D-Arabitol	Structural Classification Endogenous metabolite Saccharides Source Classification	AMPK PGC-1α
D-Arabitol is an orally active D-enantiomer of arabitol. D-Arabitol modulates the composition of gut microbiota, increases short-chain fatty acids, and promotes AMPK-PGC-1α-related browning of white adipose tissue. D-Arabitol improves weight gain, fat accumulation, insulin resistance, lipid deposition and inflammatory responses. D-Arabitol serves as the sole carbon/energy source for Bacillus methanolicus MGA3, a strain that can co-utilize it with mannitol. D-Arabitol is applicable to obesity-related research .

HY-N7515

Pinocembrin chalcone 2',4',6'-Trihydroxychalcone	Chalcones Flavonoids other families Classification of Application Fields Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields Source Classification	Bacterial AMPK
Pinocembrin chalcone (2',4',6'-Trihydroxychalcone) is an antibacterial compound from Helichrysum Trilineatum. Pinocembrin chalcone facilitates AMP-activated protein kinase (AMPK) activation, improves glucose tolerance, increases muscle FAO and reduces fat accumulation in the liver and skeletal muscles in high-fat diet-induced (HFD) diabetic mice. Pinocembrin chalcone is promising for research of gastric ulcers and diabetes .

HY-N2840

Allitol 1 Publications Verification Allodulcitol	Structural Classification Natural Products Microorganisms Classification of Application Fields Metabolic Disease Disease Research Fields Sweeteners Source Classification Food Research	Others
Allitol (Allodulcitol) is an orally active rare sugar alcohol found in Itea virginica L, Tylopilus plumbeoviolaceus. Allitol has anti-obesity and hypoglycaemic activities. Allitol reduces carcass and total body fat mass, increases cecal weight, surface area, and short-chain fatty acid production, and upregulates cecal microbial enzymes linked to butyrate metabolism. Allitol can be used for the researches of obesity and diabetes .

HY-W009417

Cedryl acetate	Structural Classification Classification of Application Fields Terpenoids Sesquiterpenes Taxodiaceae Metabolic Disease Plants Cunninghamia lanceolata var. konishii Disease Research Fields Source Classification	Environmental Pollutants Glycosidase
Cedryl acetate is an orally active α-glucosidase inhibitor with an IC₅₀ of 94 μM against yeast α-glucosidase. Cedryl acetate reduces high-fat diet-induced body weight gain, visceral fat pad weight, adipocyte hypertrophy, hepatic lipid accumulation, glucose intolerance, insulin resistance and gluconeogenesis. Cedryl acetate can be used in the research of obesity and obesity-related metabolic syndrome .

HY-N7074

Lanolin	Structural Classification Natural Products Animals Classification of Application Fields Inflammation/Immunology Disease Research Fields Source Classification	Environmental Pollutants Bacterial
Lanolin is a yellow fat that can be extracted from wool. Lanolin can be used as a skin moisturizer and applied topically to relieve nipple pain and chapping during lactation .

HY-B0757A

(±)-α-Tocopherol nicotinate rel-Vitamin E Nicotinate	Cardiovascular Disease Alkaloids Classification of Application Fields Pyridine Alkaloids Endogenous metabolite Disease Research Fields Source Classification	Reactive Oxygen Species (ROS) Endogenous Metabolite
(±)-α-Tocopherol nicotinate, vitamin E - nicotinate, is an orally active fat-soluble antioxidant that prevents lipid peroxidation in cell membranes. (±)-α-Tocopherol nicotinate is hydrolysed in the blood to α -tocopherol and niacin and may be used in studies of related vascular diseases .

HY-N2423

Sinigrin hydrate 4 Publications Verification Allyl-glucosinolate hydrate; 2-Propenyl-glucosinolate hydrate	Infection other families Classification of Application Fields Glucosinolates Plants Inflammation/Immunology Disease Research Fields Source Classification	p38 MAPK AMPK Bacterial Fungal Interleukin Related PPAR CDK PI3K Akt mTOR Apoptosis Reactive Oxygen Species (ROS)
Sinigrin (Allyl-glucosinolate) hydrate is an orally active glucosinolate found in cruciferous plants. Sinigrin hydrate possesses multiple activities such as anti-cancer, antibacterial, antifungal, anti-inflammatory, antioxidant, and inhibition of fat synthesis. Sinigrin hydrate can be used in the research of tumors, inflammatory, and metabolic diseases .

HY-N4294

Arjungenin	Triterpenes Classification of Application Fields Terpenoids Combretaceae Metabolic Disease Terminalia chebula Retz. Plants Disease Research Fields Source Classification	FXR Insecticide
Arjungenin, a pentacyclic triterpenoid compound, is a FXR agonist. Arjungenin can improve insulin sensitivity by regulating the function of fat cells. Arjungenin exhibits moderate free radical scavenging activity. Arjungenin has growth inhibitory activity against the insect Spilarctia obliqua. Arjungenin has significant antiviral activity against a series of viruses such as chikungunya Virus (CHIKV) .

HY-123033C

Nicotinamide riboside malate 20+ Cited Publications	Natural Products Neurological Disease Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Sirtuin Endogenous Metabolite
Nicotinamide riboside malate, an orally active NAD ⁺ precursor, increases NAD ⁺ levels and activates SIRT1 and SIRT3. Nicotinamide riboside malate is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities . Nicotinamide riboside malate reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease .

HY-123033AR

Nicotinamide riboside chloride (Standard)	Alkaloids Structural Classification Animals Pyridine Alkaloids Source Classification	Reference Standards Sirtuin Endogenous Metabolite
Nicotinamide riboside (chloride) (Standard) is the analytical standard of Nicotinamide riboside (chloride). This product is intended for research and analytical applications. Nicotinamide riboside Chloride, an orally active NAD+ precursor, increases NAD+ levels and activates SIRT1 and SIRT3. Nicotinamide riboside Chloride is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities[1]. Nicotinamide riboside Chloride reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease[2].

HY-17462

Adrenosterone (+)-Adrenosterone	Classification of Application Fields Endogenous metabolite Disease Research Fields Endocrinology Steroids Source Classification	Androgen Receptor Endogenous Metabolite
Adrenosterone ((+)-Adrenosterone) is a competitive hydroxysteroid (11-beta) dehydrogenase 1 (HSD11β1) inhibitor. Adrenosterone is a steroid hormone with weak androgenic effect. Adrenosterone is a dietary supplement that can decrease fat and increase muscle mass. Adrenosterone acts as a suppressor of metastatic progression of human cancer cells .

HY-Y0781R

Pyruvic acid (Standard) Acetylformic acid (Standard)	Structural Classification Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Cardiovascular System Disorder Source Classification	Reference Standards Endogenous Metabolite
Pyruvic acid (Standard) is the analytical standard of Pyruvic acid. This product is intended for research and analytical applications. Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats.

HY-126400

Tocopherols	Natural Products Nitrariaceae Peganum harmala L. Plants Source Classification	Endogenous Metabolite
Tocopherols are an important class of fat-soluble vitamins, the most common form of which is gamma-tocopherol, followed by beta-tocopherol and alpha-tocopherol .

HY-N14035

Garcinia cambogia extract	Structural Classification Natural Products Guttiferae Garcinia cambogia Desr. Plants Source Classification	FABP PPAR
Garcinia cambogia extract is an orally active anti-obesity agent . Garcinia cambogia extract upregulates the gene expression of aP2, SREBP1c, PPARγ2 and C/EBPα. Garcinia cambogia extract reduces the rate of body weight gain, visceral fat accumulation, lipid levels in blood and liver, as well as plasma insulin and leptin levels . Garcinia cambogia extract ameliorates high-fat diet-induced obesity .

HY-B2219A

Calcium stearate Maximum Cited Publications 22 Publications Verification	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification Cancer	Environmental Pollutants Endogenous Metabolite
Calcium stearate is an orally active long-chain dietary saturated fatty acid that can significantly reduce visceral fat by inducing apoptosis of preadipocytes. Calcium stearate can be used in the study of cardiovascular and metabolic diseases .

HY-N0324R

Cholic acid (Standard) 15+ Cited Publications	Structural Classification Human Gut Microbiota Metabolites Microorganisms Other disease Classification of Application Fields Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields Steroids Source Classification	Reference Standards Endogenous Metabolite
Cholic acid (Standard) is the analytical standard of Cholic acid. This product is intended for research and analytical applications. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid is orally active .

HY-B2219R

Stearic acid (Standard) 20+ Cited Publications	Structural Classification Immune System Disorder Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Reference Standards Endogenous Metabolite Apoptosis
Stearic acid (Standard) is the analytical standard of Stearic acid. This product is intended for research and analytical applications. Stearic acid is a long-chain dietary saturated fatty acid that can significantly reduce visceral fat by inducing apoptosis of preadipocytes. Stearic acid can be used in the study of cardiovascular and metabolic diseases .

HY-B0511R

Biotin (Standard) Vitamin B7 (Standard); Vitamin H (Standard); D-Biotin (Standard)	Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Reference Standards
Biotin (Standard) is the analytical standard of Biotin. Biotin, vitamin B7 and serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. Biotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids .

Cat. No.	Product Name	Chemical Structure

HY-N0324S

Cholic acid-d4 3 Publications Verification
Cholic acid-d₄ is the deuterium labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.

HY-N2041S

Myristic acid-d27 2 Publications Verification
Myristic acid-d₂₇ is the deuterium labeled Myristic acid. Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.

HY-B1788S

Taurocholic acid-d4 sodium 1 Publications Verification
Taurocholic acid-d₄ (sodium) is the deuterium labeled Taurocholic acid. Taurocholic acid (N-Choloyltaurine) is a bile acid involved in the emulsification of fats.

HY-B2219S4

Stearic acid-d35
Stearic Acid-d₃₅ is the deuterium labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.

HY-B2219S3

Stearic acid-d3
Stearic acid-d₃ is the deuterium labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.

HY-B2219S2

Stearic acid-13C18 1 Publications Verification
Stearic acid- ¹³C₁₈is the ¹³C-labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.

HY-N0324S2

Cholic acid-13C
Cholic acid- ¹³C is the ¹³C-labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.

HY-N2334S

Glycochenodeoxycholic acid-d4
Glycochenodeoxycholic acid-d₄ is the deuterium labeled Glycochenodeoxycholic acid. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) induces hepatocyte apoptosis .

HY-B0234S2

Estrone-d4
Estrone-d₄ is the deuterium labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells .

HY-Y0781S

Pyruvic acid-13C sodium
Pyruvic acid- ¹³C (sodium) is the ¹³C-labeled Pyruvic acid. Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats.

HY-Y0781S1

Pyruvic acid-13C
Pyruvic acid- ¹³C is the ¹³C labeled Pyruvic acid . Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats .

HY-B2219S9

Stearic acid-d7
Stearic acid-d₇ is the deuterium labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.

HY-113016S

Elaidic acid-d9
Elaidic acid-d₉ is deuterium labeled Elaidic acid. Elaidic acid is the major trans fat found in hydrogenated vegetable oils and can be used as a pharmaceutical solvent .

HY-N0324S1

Cholic acid-d5
Cholic acid-d₅ is the deuterium labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.

HY-B0511S3

Biotin-13C5
Biotin- ¹³C₅ (Vitamin B7- ¹³C₅) is ¹³C labeled Biotin. Biotin, vitamin B7 and serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. Biotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids .

HY-W750263

Pyruvic acid-13C2
Pyruvic acid- ¹³C₂ (Acetylformic acid- ¹³C₂) is the ¹³C-labeled Pyruvic acid (HY-Y0781). Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats.

HY-N0378S1

D-Mannitol-13C

D-Mannitol- ¹³C is the ¹³C labeled D-Mannitol (HY-N0378). D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β₃-adrenergic receptor (β₃-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells . D-Mannitol is commonly used to maintain osmotic pressure between the plant cytoplasm and the culture medium and protect cells when the cell wall is weakened or even removed .

HY-W013061S1

Propane-1,2,3-triyl tripalmitate-13C3
Propane-1,2,3-triyl tripalmitate- ¹³C₃ is the ¹³C labeled Propane-1,2,3-triyl tripalmitate (HY-W013061). Propane-1,2,3-triyl tripalmitate is a saturated fat. Propane-1,2,3-triyl tripalmitate enhances the lymphatic transport of Glycerol tristearate (HY-127035) .

HY-B1788S1

Taurocholic acid-d4 1 Publications Verification
Taurocholic acid-d₄ is deuterium labeled Taurocholic acid. Taurocholic acid (N-Choloyltaurine) is a bile acid involved in the emulsification of fats.

HY-B2219S6

Stearic acid-d5
Stearic acid-d₅5 is the deuterium labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.

HY-B2219S7

Stearic acid-d4
Stearic acid-d₄ is the deuterium labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils .

HY-N2041S3

Myristic acid-d3
Myristic acid-d₃3 is the deuterium labeled Myristic acid. Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.

HY-N0378S2

D-Mannitol-13C6

D-Mannitol- ¹³C₆ is the ¹³C labeled D-Mannitol (HY-N0378). D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β₃-adrenergic receptor (β₃-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells . D-Mannitol is commonly used to maintain osmotic pressure between the plant cytoplasm and the culture medium and protect cells when the cell wall is weakened or even removed .

HY-B0234S1

Estrone-d2
Estrone-d₂ is the deuterium labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells .

HY-B0234S

Estrone-13C3
Estrone- ¹³C₃ is the ¹³C-labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells .

HY-Y0781S3

Pyruvic acid-1-13C-2 sodium
Pyruvic acid- ¹³C-2 (sodium) is the ¹³C labeled Pyruvic acid . Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats .

HY-B2219S

Stearic acid-1-13C
Stearic acid-1- ¹³C is the ¹³C labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.

HY-N2041S2

Myristic acid-13C
Myristic acid- ¹³C the ¹³C is labeled Myristic acid. Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.

HY-N2041S4

Myristic acid-13C3
Myristic acid- ¹³C₃ is the ¹³C labeled Myristic acid. Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.

HY-N2041S6

Myristic acid-d5
Myristic acid-d₅ is the deuterium labeled Myristic acid. Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.

HY-N2041S7

Myristic acid-d7
Myristic acid-d₇ is the deuterium labeled Myristic acid. Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.

HY-179170S

Malonyl CoA-13C3 lithium
Malonyl CoA- ¹³C₃ (Malonyl coenzyme A- ¹³C₃) lithium is the ¹³C-labeled Malonyl CoA lithium (HY-136408). Malonyl CoA (Malonyl Coenzyme A) lithium is an inhibitor of carnitine palmitoyl transferase 1 (CPT1). High Malonyl CoA lithium concentrations suppress fatty acid oxidation, while low Malonyl CoA lithium concentrations are permissive for fat oxidation .

HY-W013061S2

Propane-1,2,3-triyl tripalmitate-d31
Propane-1,2,3-triyl tripalmitate-d₃₁ is the deuterium labeled Propane-1,2,3-triyl tripalmitate (HY-W013061). Propane-1,2,3-triyl tripalmitate is a saturated fat. Propane-1,2,3-triyl tripalmitate enhances the lymphatic transport of Glycerol tristearate (HY-127035) .

HY-W721874

Adrenosterone-d10

Adrenosterone-d₁₀ ((+)-Adrenosterone-d₁₀) is the deuterium labeled Adrenosterone (HY-17462). Adrenosterone ((+)-Adrenosterone) is a competitive hydroxysteroid (11-beta) dehydrogenase 1 (HSD11β1) inhibitor. Adrenosterone is a steroid hormone with weak androgenic effect. Adrenosterone is a dietary supplement that can decrease fat and increase muscle mass. Adrenosterone acts as a suppressor of metastatic progression of human cancer cells .

HY-W014901S

Bisphenol F-13C6

Bisphenol F- ¹³C₆ is the ¹³C labeled Bisphenol F (HY-W014901). Bisphenol F is an orally active endocrine disruptor. Bisphenol F promotes ROS generation, upregulates p-AKT/p-GSK3β, and induces Apoptosis. Bisphenol F interferes with glucose metabolism, affects neurodevelopment and reproductive function. Bisphenol F reduces social novelty preference in mouse offspring. Bisphenol F can be used in bone, blood, and fat-related studies. Bisphenol F is used as a substitute for Bisphenol A (HY-18260) .

HY-N2041S8

Myristic acid-13C2
Myristic acid- ¹³C₂ is the ¹³C-labeled Myristic acid (HY-N2041). Myristic acid is an orally active saturated 14-carbon fatty acid found in most animal and plant fats, especially milk fat coconut oil, palm oil and nutmeg oil. Myristic acid exerts anti-inflammatory activity through the NF-κB pathway. Myristic acid has antibacterial, anti-inflammatory and analgesic properties .

HY-B2219S1

Stearic acid-d2
Stearic acid-d₂ is the deuterium labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.

HY-N0378S4

D-Mannitol-d2

D-Mannitol-d₂ is the deuterium labeled D-Mannitol (HY-N0378). D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β₃-adrenergic receptor (β₃-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells . D-Mannitol is commonly used to maintain osmotic pressure between the plant cytoplasm and the culture medium and protect cells when the cell wall is weakened or even removed .

HY-W014901S1

Bisphenol F-13C12

Bisphenol F- ¹³C₁₂ is the ¹³C labeled Bisphenol F (HY-W014901). Bisphenol F is an orally active endocrine disruptor. Bisphenol F promotes ROS generation, upregulates p-AKT/p-GSK3β, and induces Apoptosis. Bisphenol F interferes with glucose metabolism, affects neurodevelopment and reproductive function. Bisphenol F reduces social novelty preference in mouse offspring. Bisphenol F can be used in bone, blood, and fat-related studies. Bisphenol F is used as a substitute for Bisphenol A (HY-18260) .

HY-B0896S1

Triacetin-d5
Triacetin-d₅ is the deuterium labeled Triacetin. Triacetin is an artificial chemical compound, is the triester of glycerol and acetic acid, and is the second simplest fat after triformin.

HY-B2219S8

Stearic acid-d1
Stearic acid-d is the deuterium labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.

HY-Y0781S5

Pyruvic acid-13C,d4
Pyruvic acid- ¹³C,d₄ is the deuterium and ¹³C labeled Pyruvic acid . Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats .

HY-B0896S2

Triacetin-d9
Glyceryl Triacetate-d₉ is the deuterium labeled Triacetin . Triacetin is an artificial chemical compound, is the triester of glycerol and acetic acid, and is the second simplest fat after triformin.

HY-113016S1

Elaidic acid-d17
Elaidic acid-d₁₇ is deuterium labeled Elaidic acid. Elaidic acid is the major trans fat found in hydrogenated vegetable oils and can be used as a pharmaceutical solvent .

HY-N2041S1

Myristic acid-d2
Myristic acid-d₂ is the deuterium labeled Myristic acid. Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.

HY-B2219S5

Stearic acid-9,10-d2
Stearic acid-9,10-d₂ is the deuterium labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.

HY-N0378S

D-Mannitol-d8

D-Mannitol-d₈ is the deuterium labeled D-Mannitol (HY-N0378). D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β₃-adrenergic receptor (β₃-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells . D-Mannitol is commonly used to maintain osmotic pressure between the plant cytoplasm and the culture medium and protect cells when the cell wall is weakened or even removed .

HY-N0378S5

D-Mannitol-d1

D-Mannitol-d is the deuterium labeled D-Mannitol (HY-N0378). D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β₃-adrenergic receptor (β₃-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells . D-Mannitol is commonly used to maintain osmotic pressure between the plant cytoplasm and the culture medium and protect cells when the cell wall is weakened or even removed .

HY-N0378S3

D-Mannitol-2-13C

D-Mannitol-2- ¹³C is the ¹³C labeled D-Mannitol (HY-N0378). D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β₃-adrenergic receptor (β₃-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells . D-Mannitol is commonly used to maintain osmotic pressure between the plant cytoplasm and the culture medium and protect cells when the cell wall is weakened or even removed .

HY-N0378S6

D-Mannitol-13C,d2

D-Mannitol- ¹³C,d₂ is the deuterium and ¹³C labeled D-Mannitol (HY-N0378). D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β₃-adrenergic receptor (β₃-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells . D-Mannitol is commonly used to maintain osmotic pressure between the plant cytoplasm and the culture medium and protect cells when the cell wall is weakened or even removed .

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0378AGL

D-Mannitol, M200 (GMP Like) Mannitol, M200 (GMP Like); Mannite, M200 (GMP Like)	Endogenous Metabolite Apoptosis Adrenergic Receptor PGC-1α PKA	Cardiovascular Disease Metabolic Disease Cancer
D-Mannitol, M200 (GMP Like) (Mannitol, M200 (GMP Like)) is the GMP Like class D-Mannitol that can be used as pharmaceutical excipients. D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β3-adrenergic receptor (β3-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells .

HY-N0378BGL

D-Mannitol, M100 (GMP Like) Mannitol, M100 (GMP Like); Mannite, M100 (GMP Like)	Endogenous Metabolite Apoptosis Adrenergic Receptor PGC-1α PKA	Cardiovascular Disease Metabolic Disease Cancer
D-Mannitol, M100 (GMP Like) (Mannitol, M100 (GMP Like)) is the GMP Like class D-Mannitol that can be used as pharmaceutical excipients. D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β3-adrenergic receptor (β3-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells .

HY-10585AG

Valproic acid sodium Sodium Valproate; VPA sodium; 2-Propylpentanoic acid sodium	Organoid HDAC Autophagy Mitophagy HIV Notch Apoptosis Endogenous Metabolite	Infection Neurological Disease Metabolic Disease Cancer
Valproic acid (Sodium Valproate) sodium is an orally active HDAC inhibitor, with IC₅₀ in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC₅₀, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid sodium activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium is used in the treatment of epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine headaches .

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