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Probe

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3436

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10

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2316

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154

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94

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4

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3

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42

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Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D0080
    Laurdan
    20+ Cited Publications

    		 Fluorescent Dye Others
    Laurdan is a membrane-permeable fluorescent probe that displays spectral sensitivity to the phospholipid phase of the cell membrane to which it is bound. Quantitation of generalized polarization (GP) of Laurdan can be used to identify phospholipid phase (Ex/Em = 370/440-490 nm).
    Laurdan
  • HY-D1563
    pH Receptor Probe
    1 Publications Verification

    		 Fluorescent Dye Others
    pH Receptor Probe is a pH-sensitive cyanine derivative and a environmental sensitive fluorophore. pH Receptor Probe has a pH-sensitive maximal absorption at 644 nm and emission at 664 nm. pH Receptor Probe has been used as a pH sensor of lysosomal compartments .
    pH Receptor Probe
  • HY-135136
    Aldehyde reactive probe TFA

    		Biochemical Assay Reagents Fluorescent Dye Others
    Aldehyde reactive probe (TFA) is a biotinylated reagent for the detection and quantification of AP sites in damaged DNA .
    Aldehyde reactive probe TFA
  • HY-D1458
    Peroxyfluor 1

    		Fluorescent Dye Cardiovascular Disease Neurological Disease Cancer
    Peroxyfluor 1 is a cell-permeable probe for H2O2. Peroxyfluor 1 represents a first-generation, green-fluorescent probe .
    Peroxyfluor 1
  • HY-D1244
    CO probe 1

    		Fluorescent Dye Cardiovascular Disease Inflammation/Immunology
    CO probe 1 (probe 2) is a highly efficient fluorescent CO probe (Ex=493 nm) with an allyl ether reaction site. In the presence of PdCl₂, CO reduces Pd 2+ to Pd 0, triggering a Tsuji-Trost reaction that removes the allyl protecting group, releases fluorescein, and generates a significant fluorescence signal. CO probe 1 has high selectivity, rapid response (fluorescence enhancement of 150 times within 20 minutes), and low cytotoxicity, and can be used for real-time imaging of CO in living cells. CO probe 1 may be used to study pathological mechanisms involving CO signaling regulation, such as inflammation, vascular disease, or cancer .
    CO probe 1
  • HY-D0133
    NBD-X acid

    		Fluorescent Dye Others
    NBD-X acid is a fluorescent probe containing a nitrobenzoxadiazole group. NBD-X acid can be used to study the structure and function of biomolecules .
    NBD-X acid
  • HY-101859
    NucPE1
    5 Publications Verification

    Nuc-H2O2 Probe

    		 Reactive Oxygen Species (ROS) Others
    NucPE1 (Nuc-H2O2 Probe) is a nuclear-localized fluorescent hydrogen peroxide that is specifically localized to cellular nuclei without appended targeting moieties.
    NucPE1
  • HY-115691
    STY-BODIPY

    Styrene-BODIPY; Styrene-Conjugated BODIPY

    		 Fluorescent Dye Others
    STY-BODIPY (Styrene-BODIPY; Styrene-Conjugated BODIPY) is a styrene-conjugated fluorescent probe used to measure the activity of radical-trapping antioxidants (RTAs)> .
    STY-BODIPY
  • HY-DY1025
    Laurdan (solution)

    		Fluorescent Dye Others
    Laurdan (solution) is a membrane-permeable fluorescent probe that displays spectral sensitivity to the phospholipid phase of the cell membrane to which it is bound. Quantitation of generalized polarization (GP) of Laurdan can be used to identify phospholipid phase.
    Solvent and concentration: DMSO: 5 mM
    Laurdan (solution)
  • HY-147652
    G-quadruplex DNA fluorescence probe 1

    		DNA Stain Others
    G-quadruplex DNA fluorescence probe 1 (Compound E1) is a selective G-quadruplex DNA targeting fluorescent probe. G-quadruplex DNA fluorescence probe 1 can pass through membrane and enter living cells with low cytotoxicity .
    G-quadruplex DNA fluorescence probe 1
  • HY-D2186
    BTD probe-1
    1 Publications Verification

    		 Biochemical Assay Reagents Others
    BTD probe-1 is a benzothiazine-based chemoproteomic probe and selective protein S-sulfenic acid (Cys-SOH) labeling agent. BTD probe-1 labels protein S-sulfenic acids in vitro in cell and tissue samples, and in situ in intact cells, enabling detection or enrichment of modified proteins/peptides. BTD probe-1 exhibits no cytotoxicity in cells at concentrations ≤1 mM. BTD probe-1 enables global, site-specific mapping and quantification of cysteine S-sulfenylation in complex proteomes with lower input material .
    BTD probe-1
  • HY-D1148
    HKGreen-4I
    1 Publications Verification

    		 Fluorescent Dye Others
    HKGreen-4I is a highly sensitive green fluorescent probe for the specific detection of ONOO - in living cells with a maximum excitation wavelength and emission wavelength of 520 nm and 543 nm, respectively .
    HKGreen-4I
  • HY-D0127
    Merocyanin 540

    		Fluorescent Dye Others
    Merocyanin 540 is a fluorescent membrane probe that selectively stains the membranes of a wide variety of electrically excitable cells, but not those of nonexcitable cells (Ex/Em: 540/580 nm) .
    Merocyanin 540
  • HY-D2775
    Cobalt(II) ions probe 1

    		Fluorescent Dye Others
    Cobalt(II) ions probe 1 (Compound L) is a fluorescent sensor for Co 2+ detecting in biological environments. Cobalt(II) ions probe 1 can selectively bind with Co 2+ in the presence of other metal ions (Ex: 380 nm) .
    Cobalt(II) ions probe 1
  • HY-135235
    Cysteine thiol probe
    1 Publications Verification

    		 Fluorescent Dye Others
    Cysteine Thiol Probe is a thiol-based probe designed to label electrophilic natural products. Cysteine Thiol Probe possesses each of the characteristics of an ideal pharmacophore probe, and has a chromophore. Cysteine Thiol Probe is capable of engaging enone-, β-lactam-, and β-lactone-based electrophilic metabolites .
    Cysteine thiol probe
  • HY-162160
    NR12S

    		Fluorescent Dye Others
    NR12S is a fluorescence probe. NR12S can be used for the research of studying cholesterol and lipid order in biomembranes .
    NR12S
  • HY-D2329
    Fluorescein-PEG4-NHS ester

    		Fluorescent Dye Others
    Fluorescein-PEG4-NHS ester is a colorimetric probe formed by the reaction of adipic dihydrazide and fluorescein isothiocyanate .
    Fluorescein-PEG4-NHS ester
  • HY-D2912
    Cys-shift probe-1

    		Biochemical Assay Reagents Others
    Cys-shift probe-1 (compound 13) is a potent Cys-shift probe. Cys-shift probe-1 can improve the ion mobility of labeled peptides and be used in protein analysis .
    Cys-shift probe-1
  • HY-157916
    ARP

    Aldehyde reactive Probe

    		 Fluorescent Dye Others
    ARP (Aldehyde reactive probe) is an aldehyde-reactive probe . ARP specifically labels AP sites in DNA with biotin residues . ARP detects abasic sites induced by RNA oxidation . ARP is suitable for studies involving the quantification of AP sites, or the detection of other aldehyde-containing DNA damages and abasic sites induced by RNA oxidation .
    ARP
  • HY-D2315
    Probe-Cys

    		Fluorescent Dye Cancer
    Probe-Cys is a water-soluble and selective near-infrared fluorescent probe for Cysteine (Cys) (λex= 680 nm, λem=710 nm) that is not interfered by Hcy, GSH, and HS-. Probe-Cys can react with the stimulant DTT (HY-15917) and the NEM (HY-D0843) in HepG2 cells and zebrafish for the detection of endogenous Cys. Probe-Cys can also be used for imaging Cys in Arabidopsis thaliana. Probe-Cys provides a method for cancer diagnosis and exploration of plant sulfur metabolism .
    Probe-Cys
  • HY-158000
    Bile acid probe 1

    		Fluorescent Dye Metabolic Disease
    Bile acid probe 1, a clickable and photoreactive probe for Bile acid, contains ester linkage .
    Bile acid probe 1
  • HY-158779
    Sulfane sulfur probe 4

    SSP4

    		 Fluorescent Dye Others
    Sulfane sulfur probe 4 (SSP4) is a fluorescent probe used to detect sulfane sulfur species (Ex/Em=494/515 nm). Sulfane sulfur probe 4 exhibits high sensitivity in detecting sulfane sulfur, even in the presence of other substances such as homocysteine, methionine, cysteine, glutathione, N-acetyl-L-cysteine, glycine, tyrosine, tryptophan, arginine, and metal ions (Fe 2+, Fe 3+, Mg 2+, Ca 2+, and Zn 2+) .
    Sulfane sulfur probe 4
  • HY-DY1071
    pH Receptor Probe (solution)

    		Fluorescent Dye Others
    pH Receptor Probe (solution) is a pH-sensitive cyanine derivative and a environmental sensitive fluorophore. pH Receptor Probe has a pH-sensitive maximal absorption at 644 nm and emission at 664 nm. pH Receptor Probe has been used as a pH sensor of lysosomal compartments .
    Solvent and concentration: DMSO: 10 mM
    pH Receptor Probe (solution)
  • HY-143678
    Citrulline-specific probe-biotin

    		Biochemical Assay Reagents Others
    Citrulline-specific probe-biotin is a biotinylated probe for detection of citrulline. Citrulline is the hydrolysis product of arginine catalyzed by protein arginine deiminase (PAD). PAD is abnormally activated in many diseases, leading to increased citrulline levels. Citrulline-specific probe-biotin is a biological probe that can identify diseases showing abnormal increases in PAD activity .
    Citrulline-specific probe-biotin
  • HY-W040681
    7-Dimethylaminocoumarin-4-acetic acid

    		Fluorescent Dye Others
    7-Dimethylaminocoumarin-4-acetic acid is a fluorescent probe .
    7-Dimethylaminocoumarin-4-acetic acid
  • HY-D1022A
    Biotin-16-dUTP trisodium

    Biotin-16-deoxyuridine-5'-triphosphate trisodium

    		 DNA Stain Others
    Biotin-16- dUTP (Biotin-16-deoxyuridine-5'-triphosphate) trisodium can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP trisodium can be used to produce biotinylated DNA probes in a variety of assay applications .
    Biotin-16-dUTP trisodium
  • HY-D1151
    HKOH-1
    3 Publications Verification

    		 Reactive Oxygen Species (ROS) Fluorescent Dye Others
    HKOH-1 is a highly sensitive green fluorescent probe for the specific detection of ·OH in living cells with a maximum excitation wavelength and emission wavelength of 500 nm and 520 nm, respectively .
    HKOH-1
  • HY-D1478
    Fluorescent polyamine probe-1

    		Fluorescent Dye Others
    Fluorescent polyamine probe-1 (compound 15) is a linear polyamine probe with high uptake efficiency. Fluorescent polyamine probe-1 can be used for the research of transport system into cancer cells .
    Fluorescent polyamine probe-1
  • HY-D2476
    H2S Fluorescent probe 1

    		Fluorescent Dye Others
    H2S Fluorescent probe 1 (Compound 2) is a fluorescent probe that detects hydrogen sulfide (H2S) with almost no cytotoxicity. Upon the addition of increasing amounts of HS - to DMSO solution of H2S Fluorescent probe 1, a new absorption peak appears gradually at 485 nm. H2S Fluorescent probe 1, the fluorescence intensity notes at 434 nm increasing rapidly by titration of HS - .
    H2S Fluorescent probe 1
  • HY-D1377
    Citrulline-specific probe-rhodamine hydrate

    		Fluorescent Dye Others
    Citrulline-specific probe-rhodamine hydrate is a specific probe for citrulline (Citrulline) combined with a rhodamine fluorescent group. Citrulline is the hydrolysis product of arginine catalyzed by protein arginine deiminase (PAD). PAD is abnormally activated in many diseases, leading to increased citrulline levels. Citrulline-specific probe-rhodamine hydrate is a biological probe that can identify diseases showing abnormal increases in PAD activity and may be effectively used in animal models of ulcerative colitis .
    Citrulline-specific probe-rhodamine hydrate
  • HY-D1302
    Near-IR fluorescent probe-1

    		Fluorescent Dye Others
    Near-IR fluorescent probe-1 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    Near-IR fluorescent probe-1
  • HY-D2418
    PS-SCOTfluor-12

    		Fluorescent Dye Metabolic Disease
    PS-SCOTfluor-12 (compound 10) is a fluorescent probe for imaging Lactic acid (HY-B2227) metabolism in live cells. λex/λem= 485/605 nm .
    PS-SCOTfluor-12
  • HY-130013
    HKYellow-AM (6/12-mixture)

    		Fluorescent Dye Others
    HKYellow-AM (6/12-mixture) is a yellow fluorescent probe that can detect ONOO- in living cells and tissues with high selectivity and sensitivity without cytotoxicity .
    HKYellow-AM (6/12-mixture)
  • HY-D1022
    Biotin-16-dUTP

    Biotin-16-deoxyuridine-5'-triphosphate

    		 Fluorescent Dye Others
    Biotin-16-dUTP (Biotin-16-deoxyuridine-5'-triphosphate) can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .
    Biotin-16-dUTP
  • HY-D1631A
    Calcium green-5N hexapotassium

    		Fluorescent Dye Neurological Disease
    Calcium green-5N hexapotassium is a cell-impermeant Ca 2+-sensitive fluorescent probe. Calcium green-5N hexapotassium shows enhancement in fluorescence intensity on binding Ca 2+, and can monitor free Ca 2+ in neurons .
    Calcium green-5N hexapotassium
  • HY-D1188
    PARP7-probe-1

    		PARP Cancer
    PARP7-probe-1 is a chemiluminescent labeled PARP7 probe. PARP7-probe-1 is a biotinylated probe binding to the PARP7 active site. PARP7-probe-1 can be used for the research of PARP7 function .
    PARP7-probe-1
  • HY-135640
    TAMRA-probe 1

    		Fluorescent Dye Others
    TAMRA-probe 1 is a commonly used fluorescent probe for labeling .
    TAMRA-probe 1
  • HY-176846
    HIPS probe-1

    		Biochemical Assay Reagents Others
    HIPS probe-1 (Compound 1) is a click chemistry reagent containing a alkyne group. HIPS probe-1 can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. HIPS probe-1 can be used as a chemical probe to specifically recognize and label aldehyde functional groups in DNA, especially abasic sites (AP sites) for DNA damage research .
    HIPS probe-1
  • HY-D1412
    LPd peroxida probe-1
    1 Publications Verification

    		 Ferroptosis Others
    LPd peroxida probe-1, a marker of ferroptosis, is a useful fluorescent probe for investigating the roles of lipid peroxidation in a variety of cell pathophysiologies. LPd peroxida probe-1 reduces lipid hydroperoxides to lipid alcohols and is used for imaging lipid hydroperoxides in living cells .
    LPd peroxida probe-1
  • HY-P5909F
    FITC-labeled Keap1-Nrf2 probe

    		Keap1-Nrf2 Others
    FITC-labeled Keap1-Nrf2 probe is aFITC-labeled Keap1-Nrf2 probe (HY-P5909).
    FITC-labeled Keap1-Nrf2 probe
  • HY-D2377
    F8

    		Fluorescent Dye Others
    F8 is a small molecule GPR84 fluorescent probe that can visualize and detect GPR84 protein levels at the cellular and tissue levels .
    F8
  • HY-D2331
    ZL-12A probe

    		DNA/RNA Synthesis Fluorescent Dye Others
    ZL-12A probe is a "stereoprobe "that can promote the degradation of TFIIH helicase ERCC3. ZL-12A degrades ERCC3 by covalently modifying C342 .
    ZL-12A probe
  • HY-D2999
    NIR-RED ATP Probe

    		Fluorescent Dye Metabolic Disease
    NIR-RED ATP Probe is a NIR-II fluorescent probe. NIR-RED ATP Probe exhibits high affinity and selectivity for ATP and can non-invasively and with high contrast detect changes in ATP concentration at the cellular level, with minimal interference to the abundant biomolecules within the cells. NIR-RED ATP Probe can be used as a biomarker detection tool for drug-induced liver injury (DILI) .
    NIR-RED ATP Probe
  • HY-135639
    Alkyne-probe 1

    		Fluorescent Dye Others
    Alkyne-probe 1 is usually used as a Alkyne-labeled chemical or fluorescent probe. Alkyne-probe 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Alkyne-probe 1
  • HY-D3002
    ONOO-/O2- tracker probe

    		Fluorescent Dye Metabolic Disease
    ONOO-/O2- tracker probe is a dual-responsive near-infrared fluorescent probe. ONOO-/O2- tracker probe will only emit a strong fluorescence signal when both peroxynitrite (ONOO⁻) and superoxide anion (O₂•⁻), the two key reactive oxygen/nitrogen species, are present simultaneously. ONOO-/O2- tracker probe can be used as a biomarker detection tool for drug-induced liver injury (DILI) .
    ONOO-/O2- tracker probe
  • HY-D3000
    NIR-RED ROS-H2O2 Probe

    		Fluorescent Dye Metabolic Disease
    NIR-RED ROS-H2O2 Probe is a near-infrared fluorescent probe used for detecting hydrogen peroxide (H₂O₂) and featuring dual-modal fluorescence/photoacoustic imaging capabilities. NIR-RED ROS-H2O2 Probe successfully detects the upregulated fluorescence signal of H₂O₂ in HepG2 cells and a mouse liver injury model. NIR-RED ROS-H2O2 Probe can be used as a biomarker detection tool for drug-induced liver injury (DILI) .
    NIR-RED ROS-H2O2 Probe
  • HY-179099
    WDR5 probe 1

    		WDR5 Drug Intermediate Cancer
    Multi-target kinase-IN-8 (compound 16) is an efficient and highly selective WDR5 chemical probe. Multi-target kinase-IN-8 is a pharmaceutical intermediate. Multi-target kinase-IN-8 can be used for cancer research .
    WDR5 probe 1
  • HY-D2115
    NBDT

    		Fluorescent Dye Others
    NBDT is sensitive and selective light-up fluorescent probe for monitoring gallium and chromium ionsin vitro and in vivo and can be detected at 574 nM .
    NBDT
  • HY-W127843
    Mag-Indo-1 tetrapotassium salt

    		Fluorescent Dye Others
    Mag-Indo-1 tetrapotassium salt is a cell impermeable fluorescent probe for Mg 2+ detection .
    Mag-Indo-1 tetrapotassium salt
  • HY-W337618
    7-Aminocoumarin

    		Fluorescent Dye Cancer
    7-Aminocoumarin is highly fluorescent, acts as an optical brightener and fluorescent probe .
    7-Aminocoumarin

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