52 Results for "

Saponin D

" in MedChemExpress (MCE) Product Catalog:
Products (52)

52 Results for "Saponin D" in MCE Product Catalog:

Cat. No.: HY-N15163
CAS No.: 79190-14-0
Saponin D is a natural product. Saponin D can be obtained from the leaves of Hovenia dulcis. The glycosidic bond of Saponin D is cleaved in an alkaline manner to yield Jujubogenin and Saponin G. A self-nanoemulsifying adjuvant with Saponin D boosts immune response and exerts an anti-lymphoma effect .
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12 Publications Verification
Cat. No.: HY-N0250
CAS No.: 20874-52-6
Saikosaponin D is a triterpene saponin isolated from Bupleurum, with anti-inflammatory, anti-bacterial, anti-tumor, and anti-allergic activities; Saikosaponin D inhibits selectin, STAT3 and NF-kB and activates estrogen receptor-β.
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9
9 Cited Publications
Cat. No.: HY-N1411
CAS No.: 58479-68-8
Platycodin D is a saponin isolated from Platycodon grandiflorus, acts as an activator of AMPKα, with anti-obesity property. WNT/β-catenin pathway mediates the anti-adipogenic effect of platycodin D .
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3 Cited Publications
Cat. No.: HY-N0265
CAS No.: 39524-08-8
Synonyms: Akebia Saponin D
Asperosaponin VI is a saponin component from Dipsacus asper. Asperosaponin VI induces osteoblast differentiation through the BMP-2/p38 and ERK1/2 signaling pathways. Asperosaponin VI protects against hypoxia-induced cardiomyocyte apoptosis by activating the PI3K/Akt and CREB pathways. Additionally, Asperosaponin VI also has antidepressant and wound-healing-promoting activities .
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3 Cited Publications
Cat. No.: HY-N4087
CAS No.: 66663-90-9
Platycodin D2 is an orally active triterpenoid saponin found in Platycodon grandiflorum. Platycodin D2 induces mitophagy in cancer cells through NIX, thereby activating the P21/CyclinA2 pathway and promoting cell senescence. Platycodin D2 induces mitochondrial dysfunction, enhances autophagy, inhibits hepatocellular carcinoma cell proliferation, and exhibits anti-tumor activity against multiple cancer cell types. Platycodin D2 promotes mRNA expression of T-bet, GATA-3, Th1 cytokines IL-2 and IFN-γ, and Th2 cytokines IL-4 and IL-10, enhances splenocyte proliferation, and acts as a vaccine adjuvant with low rabbit red blood cell hemolytic activity. Platycodin D2 induces mitochondrial ROS production, incomplete autophagy, and ferroptosis to inhibit breast cancer cell proliferation. Platycodin D2 can be used for the research of cancer, inflammation and immunology .
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3 Cited Publications
Cat. No.: HY-N0588
CAS No.: 78763-58-3
Deapioplatycodin D is a triterpenoid saponin isolated from Platycodon grandiflorum, with anti-HCV activity .
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2 Cited Publications
Cat. No.: HY-N0434
CAS No.: 84687-42-3
Astragaloside III is a triterpenoid saponin. Astragaloside III can be extracted from Astragalus root. Astragaloside III increases NKG2D and induces TACE phosphorylation. Astragaloside III induces Apoptosis. Astragaloside III has antiviral activity against dengue serotypes 1 and 3. Astragaloside III has anticancer activity against breast and colon cancer .
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1 Cited Publications
Cat. No.: HY-N0834
CAS No.: 68027-15-6
Synonyms: SB365; Hederacolchiside A
Pulsatilla saponin D (SB365), isolated from the root of Pulsatilla chinensis, is an anti-tumor agent .
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1 Cited Publications
Cat. No.: HY-N3519
CAS No.: 67884-03-1
Platycodin D3 is a triterpenoid saponin that can be found in Platycodon grandiflorum. Platycodin D3 exhibits multiple activities including anti-inflammation, regulation of airway mucus secretion, improvement of asthmatic airway inflammation and remodeling, and inhibition of hepatitis C virus (HCV) replication. The IC50 value of Platycodin D3 against HCV NS5B RNA-dependent RNA polymerase is 8 μg/mL. Platycodin D3 can be used in studies related to asthma, hepatitis C virus infection and inflammatory diseases .
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1 Cited Publications
Cat. No.: HY-N3520
CAS No.: 67884-05-3
Deapi-platycodin D3 is a triterpenoid saponin from the roots of Platycodon grandiflorum .
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1 Cited Publications
Cat. No.: HY-N2382
CAS No.: 81917-50-2
Polyphyllin H is a steroidal saponin. Polyphyllin H is isolated from Paris polyphylla. Polyphyllin H potently inhibits the activities of CYP1A2 (IC50 = 6.44 μM, competitive), CYP2D6 (IC50 = 13.88 μM, competitive) and CYP3A4 (IC50 = 4.52 μM, non-competitive, time-dependent). Polyphyllin H downregulates the expression of ABCB1 and ABCC3. Polyphyllin H binds to membrane cholesterol and disrupts lipid raft structures. Polyphyllin H restores the sensitivity of paclitaxel-resistant breast cancer cells to paclitaxel .
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1 Cited Publications
Cat. No.: HY-N4253
CAS No.: 173792-61-5
Kudinoside D is a triterpenoid saponin. Kudinoside D is isolated from the leaves of Ilex kudingcha. Kudinoside D enhances the phosphorylation levels of AMPK and its downstream molecule ACC, and inhibits the expression of PPARγ, C/EBPα, SREBP-1c as well as the target genes of adipogenic transcription factors. Kudinoside D inhibits the activity of ANO1. Kudinoside D possesses hypolipidemic activity. Kudinoside D can be used in obesity-related research .
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Cat. No.: HY-N3504
CAS No.: 65604-80-0
Ophiopogonin D' is a steroidal saponin and a SIRT1 activator. Ophiopogonin D' can also regulate the activities of transporters OATP1B1 and OATP1B3. Ophiopogonin D' exhibits certain toxicity to tumor cells. Ophiopogonin D' can be used in tumor research .
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Cat. No.: HY-N0254
CAS No.: 760961-03-3
Hederacoside D is one of the bioactive saponins from Hedera helix, and plays pivotal roles in the overall biological activity.
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Cat. No.: HY-N2506
CAS No.: 83459-41-0
Ginsenoside Ra1 is a dammarane-type bisdesmosidic saponin present in the roots of Panax ginseng. Ginsenoside Ra1 is hydrolyzed by gut-derived β-D-xylosidase to Ginsenoside Rb2 (HY-N0040). Ginsenoside Ra1 inhibits hypoxia/reoxygenation-induced activation of protein tyrosine kinase (PTK) .
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Cat. No.: HY-N5040
CAS No.: 1137648-52-2
Ilexhainanoside D is the main triterpenoid saponin extracted from Ilex hainanensis Merr., and the combination of Ilexhainanoside D and ilexsaponin A1 has anti-inflammation effect .
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Cat. No.: HY-N0265R
CAS No.: 39524-08-8
Synonyms: Akebia Saponin D (Standard)
Asperosaponin VI (Standard) is the analytical standard of Asperosaponin VI. This product is intended for research and analytical applications. Asperosaponin VI is a saponin component from Dipsacus asper. Asperosaponin VI induces osteoblast differentiation through the BMP-2/p38 and ERK1/2 signaling pathways. Asperosaponin VI protects against hypoxia-induced cardiomyocyte apoptosis by activating the PI3K/Akt and CREB pathways. Additionally, Asperosaponin VI also has antidepressant and wound-healing-promoting activities .
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Cat. No.: HY-N6058
CAS No.: 103956-33-8
(3β)-3-[(O-β-D-Glucopyranosyl-(1→3)-O-6-deoxy-α-L-mannopyranosyl-(1→2)-α-L-arabinopyranosyl)oxy]olean-12-en-28-oic acid is a member of Oleanolic acid saponins with trematocide activity .
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Cat. No.: HY-N8610
CAS No.: 1262489-44-0
Uralsaponin D is a saponin that can be isolated from Glycyrrhiza inflata. Uralsaponin D inhibits phospholipase A2 (PLA2) with an IC50 value of 32.2 μM .
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