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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10030 Results for "
endogenous
" in MedChemExpress (MCE) Product Catalog:
Products (10030)
10030 Results for "endogenous" in MCE Product Catalog:
184
184 Publications Verification
Synonyms: Adenosine 5'-triphosphate
181
181 Cited Publications
Synonyms: Adenosine 5'-triphosphate disodium salt; Disodium adenosine triphosphate
Category:
Natural Products Plant Animal Other Families Extract Microorganism Endogenous metabolite Disease Research Fields Inflammation/Immunology
Target:
165
165 Cited Publications
Art. -Nr.: HY-K0013
MCE Protease and Phosphatase Inhibitor Cocktail (EDTA-Free, 10× in ddH2O) protects protein from degradation by endogenous proteases released during protein extraction and purification.The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
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Telaglenastat (CB-839) is a first-in-class, selective, reversible and orally active glutaminase 1 (GLS1) inhibitor. Telaglenastat selectively inhibits GLS1 splice variants KGA (kidney-type glutaminase) and GAC (glutaminase C) compared to GLS2. The IC50s are 23 nM and 28 nM for endogenous glutaminase in mouse kidney and brain, respectively. Telaglenastat inuduces autophagy and has antitumor activity .
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Telaglenastat (CB-839) hydrochloride is a first-in-class, selective, reversible and orally active glutaminase 1 (GLS1) inhibitor. Telaglenastat hydrochloride selectively inhibits GLS1 splice variants KGA (kidney-type glutaminase) and GAC (glutaminase C) compared to GLS2. The IC50s are 23 nM and 28 nM for endogenous glutaminase in mouse kidney and brain, respectively. Telaglenastat hydrochloride inudces autophagy and has antitumor activity .
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95
95 Cited Publications
Synonyms: Sodium ascorbate; Sodium L-ascorbate; Vitamin C sodium salt
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94
94 Cited Publications
Art. -Nr.: HY-D0041
CAS. Nr.: 148504-34-1
Synonyms: Calcein acetoxymethyl ester
69
Roxadustat is an orally active hypoxia-inducible factor prolyl-hydroxylase (PHD) inhibitor (HIF-PHI) that promotes erythropoiesis through increasing endogenous erythropoietin, improving iron regulation, and reducing hepcidin .
66
66 Cited Publications
Synonyms: GSH; γ-L-Glutamyl-L-cysteinyl-glycine
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47
47 Cited Publications
Synonyms: 5-Hydroxytryptamine hydrochloride; 5-HT hydrochloride
Category:
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46
46 Cited Publications
Synonyms: 2'-3'-cyclic GMP-AMP
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46
46 Cited Publications
Synonyms: 2'-3'-cyclic GMP-AMP sodium
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38
Forschungsgebiete:
37
37 Cited Publications
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37
37 Cited Publications
Art. -Nr.: HY-D0886
CAS. Nr.: 13408-09-8
Category:
Natural Products Neurological Disease Endogenous metabolite Disease Research Fields Cancer
Target:
33
33 Cited Publications
Synonyms: Cyclic GMP-AMP; 3',3'-cGAMP
Target:
Forschungsgebiete:
cGAMP (Cyclic GMP-AMP) functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. cGAMP activates stimulator of interferon genes (STING), which activates a signaling cascade leading to the production of type I interferons and other immune mediators .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
