3796 Results for "

natural waters

" in MedChemExpress (MCE) Product Catalog:
Products (3796)

3796 Results for "natural waters" in MCE Product Catalog:

230
Quercetin
Quercetin
0 Images
230 Publications Verification
Cat. No.: HY-18085
CAS No.: 117-39-5
Category:  

Flavonols Anti-aging Endocrine diseases Leguminosae Extract Plants Other Families Extract Endogenous metabolite Human Gut Microbiota Metabolites Flavonoids Microorganisms Immune System Disorder Sunscreen Disease markers Cosmetic Research Disease Research Fields Glycyrrhiza uralensis Fisch. Cancer

Target:  

Reactive Oxygen Species (ROS) PI3K Autophagy Mitophagy Apoptosis

Quercetin, a natural flavonoid, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC50 of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively .
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229
Quercetin hydrate
Quercetin hydrate
0 Images
229 Cited Publications
Cat. No.: HY-18085A
CAS No.: 849061-97-8
Target:  

PI3K Autophagy Mitophagy Apoptosis Reactive Oxygen Species (ROS)

Research Areas:  

Cancer

Quercetin hydrate, a natural flavonoid, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC50 of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively .
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224
Quercetin dihydrate
Quercetin dihydrate
0 Images
224 Cited Publications
Cat. No.: HY-N0146
CAS No.: 6151-25-3
Category:  

Flavonols Flavonoids Phenols Polyphenols Plants Other Families Extract Disease Research Fields Cancer

Target:  

PI3K Apoptosis

Quercetin dihydrate, a natural flavonoid, is a stimulator of recombinant SIRT1 and a PI3K inhibitor with IC50s of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively .
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174
Resveratrol
Resveratrol
0 Images
174 Cited Publications
Cat. No.: HY-16561
CAS No.: 501-36-0
Synonyms: trans-Resveratrol; SRT501
Category:  

Anti-aging Vitis vinifera cv. Zalema Plants Infection Vitaceae Extract Functional Molecules Sunscreen Research of Health Products Phenols Polyphenols Cosmetic Research Disease Research Fields Inflammation/Immunology Cancer

Target:  

DNA/RNA Synthesis IKK Autophagy Mitophagy Sirtuin Apoptosis Bacterial Fungal Antibiotic Keap1-Nrf2

Resveratrol (trans-Resveratrol; SRT501) is a CNS-penetrant natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator . Resveratrol is a potent pregnane X receptor (PXR) inhibitor . Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model . Resveratrol increases production of NO in endothelial cells .
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150
Retinoic acid
Retinoic acid
0 Images
150 Cited Publications
Cat. No.: HY-14649
CAS No.: 302-79-4
Purity:  99.81%
Synonyms: Vitamin A acid; all-trans-Retinoic acid; ATRA
Category:  

Ketones, Aldehydes, Acids Whitening Agent Cosmetic Research Endogenous metabolite Disease Research Fields Cancer

Target:  

Organoid RAR/RXR PPAR Endogenous Metabolite Autophagy

Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.
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142
D-Luciferin sodium
D-Luciferin sodium
0 Images
142 Cited Publications
Cat. No.: HY-12591
CAS No.: 103404-75-7
Purity:  99.92%
Synonyms: D-(-)-Luciferin sodium; Firefly luciferin sodium; Beetle Luciferin sodium
D-luciferin sodium is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We of er the firefly luciferase (HY-P1004A), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .
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142
D-Luciferin
D-Luciferin
0 Images
142 Cited Publications
Cat. No.: HY-12591A
CAS No.: 2591-17-5
Purity:  99.54%
Synonyms: D-(-)-Luciferin; Firefly luciferin; Beetle Luciferin
Category:  

Natural Products Animals Other Diseases Disease Research Fields

Target:  

Fluorescent Dye

D-luciferin is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We of er the firefly luciferase (HY-P1004A), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .
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142
D-Luciferin potassium
D-Luciferin potassium
0 Images
142 Cited Publications
Cat. No.: HY-12591B
CAS No.: 115144-35-9
Purity:  99.97%
Synonyms: D-(-)-Luciferin potassium; Firefly luciferin potassium; Beetle Luciferin potassium
D-luciferin potassium is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We offer the firefly luciferase (HY-P1004A), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .
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138
Curcumin
Curcumin
0 Images
138 Cited Publications
Cat. No.: HY-N0005
CAS No.: 458-37-7
Synonyms: Diferuloylmethane; natural Yellow 3; Turmeric yellow
Category:  

Anti-aging Zingiberaceae Extract Plants Food Research Sunscreen Pigments Phenols Polyphenols Cosmetic Research Curcuma longa Disease Research Fields Cancer

Target:  

Histone Acetyltransferase Epigenetic Reader Domain Keap1-Nrf2 Autophagy Mitophagy Influenza Virus Ferroptosis Apoptosis

Curcumin (Diferuloylmethane), a natural phenolic compound, is a p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. Curcumin is a photosensitizer against microorganisms. Curcumin shows inhibitory effects on NF-κB and MAPKs, and has diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification.
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83
Berberine chloride
Berberine chloride
0 Images
83 Cited Publications
Cat. No.: HY-18258
CAS No.: 633-65-8
Synonyms: natural Yellow 18 chloride
Category:  

Rutaceae Extract Alkaloids Phellodendron amurense Rupr. Plants Disease Research Fields Isoquinoline Alkaloids Biological Pesticide Research Cancer Agricultural Research

Target:  

Topoisomerase Autophagy Bacterial Reactive Oxygen Species (ROS) Antibiotic Endogenous Metabolite Parasite

Berberine chloride is an alkaloid that acts as an antibiotic. Berberine chloride induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Antineoplastic properties .
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80
Berberine sulfate
Berberine sulfate
0 Images
80 Cited Publications
Cat. No.: HY-N0716B
CAS No.: 633-66-9
Synonyms: natural Yellow 18 sulfate
Category:  

Alkaloids Coptis chinensis Franch. Plants Disease Research Fields Isoquinoline Alkaloids Inflammation/Immunology Ranunculaceae Extract

Target:  

Antibiotic Topoisomerase Autophagy Bacterial Reactive Oxygen Species (ROS) Parasite Apoptosis PI3K Akt Caspase JNK AP-1 NF-κB

Berberine sulfate is an alkaloid isolated from the Chinese herbal medicine Huanglian, as an antibiotic. Berberine sulfate induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Berberine sulfate has antineoplastic properties. The sulfate form improves bioavailability .
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77
Berberine chloride hydrate
Berberine chloride hydrate
0 Images
77 Cited Publications
Cat. No.: HY-17577
CAS No.: 68030-18-2
Synonyms: natural Yellow 18 chloride hydrate
Category:  

Alkaloids Coptis chinensis Franch. Plants Disease Research Fields Isoquinoline Alkaloids Cancer Ranunculaceae Extract

Target:  

Topoisomerase Autophagy Bacterial Reactive Oxygen Species (ROS) Antibiotic Endogenous Metabolite Parasite

Berberine chloride hydrate (Natural Yellow 18 chloride hydrate) is an alkaloid that acts as an antibiotic. Berberine chloride hydrate induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Antineoplastic properties .
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54
Berberine hemisulfate
Berberine hemisulfate
0 Images
54 Cited Publications
Cat. No.: HY-N0716A
CAS No.: 316-41-6
Synonyms: natural Yellow 18 hemisulfate
Category:  

Infection Alkaloids Coptis chinensis Franch. Metabolic Disease Plants Disease Research Fields Isoquinoline Alkaloids Cancer Ranunculaceae Extract

Target:  

Antibiotic Topoisomerase Autophagy Bacterial Reactive Oxygen Species (ROS) Apoptosis PI3K Akt Caspase JNK AP-1 NF-κB

Berberine hemisulfate is the hemisulfate form of Berberine (HY-N0716). Berberine hemisulfate is an alkaloid isolated from the Chinese herbal medicine Huanglian. Berberine hemisulfate exhibits anti-inflammatory, antibiobic, antitumor, cardiovascular protective and neuroprotective activity .
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51
Apigenin
Apigenin
0 Images
51 Cited Publications
Cat. No.: HY-N1201
CAS No.: 520-36-5
Synonyms: 4',5,7-Trihydroxyflavone; Apigenol; C.I. natural Yellow 1
Category:  

Flavones Plants Endogenous metabolite Human Gut Microbiota Metabolites Flavonoids Umbelliferae Extract Sunscreen Phenols Polyphenols Cosmetic Research Disease Research Fields Baccharis sarothroides A.Gray Cancer

Target:  

Autophagy Cytochrome P450 Endogenous Metabolite

Apigenin (4',5,7-Trihydroxyflavone) is a competitive CYP2C9 inhibitor with a Ki of 2 μM.
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47
Cryptotanshinone
Cryptotanshinone
0 Images
47 Cited Publications
Cat. No.: HY-N0174
CAS No.: 35825-57-1
Synonyms: Cryptotanshinon; Tanshinone c
Category:  

Quinones Samanea saman (Jacq.) Merr. Plants Disease Research Fields Naphthalene Quinones Cancer Labiatae Extract

Target:  

STAT Autophagy

Cryptotanshinone is a natural compound extracted from the root of Salvia miltiorrhiza Bunge that shows antitumor activities. Cryptotanshinone inhibits STAT3 with an IC50 of 4.6 μM.
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44
Citric acid
Citric acid
0 Images
44 Cited Publications
Cat. No.: HY-N1428
CAS No.: 77-92-9
Category:  

Cardiovascular Disease Preservatives Anti-aging Metabolic Disease Endocrine diseases Endogenous metabolite Food Research Infection Human Gut Microbiota Metabolites Microorganisms Immune System Disorder Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Disease Research Fields Inflammation/Immunology Cancer

Target:  

Environmental Pollutants Endogenous Metabolite Bacterial Apoptosis

Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .
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38
Betulinic acid
Betulinic acid
0 Images
38 Cited Publications
Cat. No.: HY-10529
CAS No.: 472-15-1
Purity:  99.06%
Synonyms: Lupatic acid; Betulic acid
Category:  

Infection Triterpenes Terpenoids Plants Other Families Extract Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:  

Apoptosis Topoisomerase HIV Autophagy Mitophagy NF-κB Endogenous Metabolite Parasite

Betulinic acid is a natural pentacyclic triterpenoid, acts as a eukaryotic topoisomerase I inhibitor, with an IC50 of 5 μM, and possesses anti-HIV, anti-malarial, anti-inflammatory and anti-tumor properties . Betulinic acid can cross the blood-brain barrier .
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35
Fisetin
Fisetin
0 Images
35 Cited Publications
Cat. No.: HY-N0182
CAS No.: 528-48-3
Category:  

Flavonols Neurological Disease Anti-aging Rosaceae Extract Metabolic Disease Plants Flavonoids Phenols Polyphenols Disease Research Fields Inflammation/Immunology Cancer Fragaria × ananassa Duch.

Target:  

Sirtuin PPAR TNF Receptor

Fisetin is a natural flavonol found in many fruits and vegetables with various benefits, such as antioxidant, anticancer, neuroprotection effects.
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35
Fisetin quarterhydrate
Fisetin quarterhydrate
0 Images
35 Cited Publications
Cat. No.: HY-N0182A
Category:  

Plants

Target:  

Sirtuin PPAR TNF Receptor

Fisetin quarterhydrate is a natural flavonol found in many fruits and vegetables with various benefits, such as antioxidant, anticancer, neuroprotection effects.
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35
Rutin trihydrate
Rutin trihydrate
0 Images
35 Cited Publications
Cat. No.: HY-W013075
CAS No.: 250249-75-3
Synonyms: Rutoside trihydrate; Quercetin 3-O-rutinoside trihydrate
Category:  

Flavonoids Combretaceae Extract Flavones Combretum micranthum G. Don Plants

Target:  

Apoptosis Endogenous Metabolite

Rutin (Rutoside) trihydrate is a multifunctional natural flavonoid glycoside. Rutin trihydrate has been demonstrating excellent antioxidant, anti-inflammatory, anti-diabetic, and anti-carcinogenic properties. Cardioprotective and neuroprotective activities .
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