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pH

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-134653
    5-Ph-IAA
    50+ Cited Publications

    		 Epigenetic Reader Domain Cancer
    5-Ph-IAA is a derivative of IAA. 5-Ph-IAA, a ligand, establishes the auxin-inducible degron 2 (AID2) system together with an OsTIR1 (F74G) mutant. AID2 induces rapid and efficient depletion of mAID-fused proteins to study protein function in living cells, causing tumor suppression .
    5-Ph-IAA
  • HY-10403
    PH-797804
    5+ Cited Publications

    		 p38 MAPK Autophagy Inflammation/Immunology Cancer
    PH-797804 is a ATP-competitive, selective p38α/p38β inhibitor (IC50=26 nM and Ki=5.8 nM for p38α; Ki=40 nM for p38β) and does not inhibit JNK2.
    PH-797804
  • HY-D0169
    Phenol Red
    1 Publications Verification

    pHenolsulfonepHthalein

    		 Environmental Pollutants Fluorescent Dye Others
    Phenol red (Phenolsulfonephthalein) is a pH indicator dye, relying on a distinct color change from pink to yellow in case of a positive reaction .
    Phenol Red
  • HY-B1610N
    Sodium Citrate Buffer, 0.1M, pH 4.0
    5+ Cited Publications

    		 Biochemical Assay Reagents Others
    Sodium Citrate Buffer, 0.1M, pH 4.0 is an acidic, aqueous buffer solution. Sodium Citrate Buffer, 0.1M, pH 4.0 resists pH fluctuations, chelates metal ions, and regulates the redox potential of the system. Sodium Citrate Buffer, 0.1M, pH 4.0 is widely used in molecular biology, immunohistochemistry (IHC), and biochemistry .
    Sodium Citrate Buffer, 0.1M, pH 4.0
  • HY-Y1968A
    Sterile 10 mM Histidine, pH 5.5 buffer

    Sterile 10 mM His-HCl, pH 5.5 buffer

    		 Biochemical Assay Reagents Others
    Sterile 10 mM Histidine, pH 5.5 buffer is a sterile solution using 10 mM histidine as the solute with its pH adjusted to 5.5, possessing both buffering capacity and biocompatibility. Sterile 10 mM Histidine, pH 5.5 buffer is widely applied in laboratory research, pharmaceutical production, cosmetics and other fields .
    Sterile 10 mM Histidine, pH 5.5 buffer
  • HY-D1563
    pH Receptor Probe
    1 Publications Verification

    		 Fluorescent Dye Others
    pH Receptor Probe is a pH-sensitive cyanine derivative and a environmental sensitive fluorophore. pH Receptor Probe has a pH-sensitive maximal absorption at 644 nm and emission at 664 nm. pH Receptor Probe has been used as a pH sensor of lysosomal compartments .
    pH Receptor Probe
  • HY-D1094
    Carboxy-SNARF 1 (5/6-mixture)
    1 Publications Verification

    SNARF 1

    		 Fluorescent Dye Others
    Carboxy-SNARF 1 (5/6-mixture) (SNARF 1) is a fluorescent probe that is sensitive to pH (Ex: 488 nm). Carboxy-SNARF 1 (5/6-mixture) can be used for measurement pH. Carboxy-SNARF 1 (5/6-mixture) exhibits a significant emission shift from yellow-orange (Em: 580 nm) to deep red fluorescence (Em: 640 nm) under acidic and basic conditions (pH=7-8), respectively .
    Carboxy-SNARF 1 (5/6-mixture)
  • HY-130283
    Methyltetrazine-Ph-NHS ester

    		PROTAC Linkers Cancer
    Methyltetrazine-Ph-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-Ph-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
    Methyltetrazine-Ph-NHS ester
  • HY-B1610M
    Sodium Citrate Buffer, 0.5M, pH 6.5

    		Biochemical Assay Reagents Others
    Sodium Citrate Buffer, 0.5M, pH 6.5 is a commonly used buffer composed of citric acid and sodium citrate. Sodium Citrate Buffer, 0.5M, pH 6.5 is widely used in molecular biology, immunohistochemistry (IHC), and biochemistry .
    Sodium Citrate Buffer, 0.5M, pH 6.5
  • HY-B1610J
    Sodium Citrate Buffer, 0.5M, pH 5.0
    1 Publications Verification

    		 Biochemical Assay Reagents Cancer
    Sodium Citrate Buffer, 0.5M, pH 5.0 is a commonly used buffer composed of citric acid and sodium citrate. Sodium Citrate Buffer, 0.5M, pH 5.0 is widely used in molecular biology, immunohistochemistry (IHC), and biochemistry .
    Sodium Citrate Buffer, 0.5M, pH 5.0
  • HY-W694629
    Triethylammonium bicarbonate buffer (1.0M pH 8.5)

    		Biochemical Assay Reagents Others
    Triethylammonium bicarbonate is a biochemical reagent that can be used to prepare buffer solutions that maintains the stable pH environment required for processes such as enzyme-catalyzed reactions .
    Triethylammonium bicarbonate buffer (1.0M pH 8.5)
  • HY-112798
    PH-002

    		Apolipoprotein Neurological Disease
    PH-002 is an inhibitor of apolipoprotein (apo) E4 intramolecular domain interaction in neuronal cells that could rescue impairments of mitochondrial motility and neurite outgrowth.
    PH-002
  • HY-160113
    Sodium phosphate buffer 0.02 M, pH 6.9

    		Biochemical Assay Reagents Others
    Sodium phosphate buffer 0.02 M, pH 6.9 is a commonly used aqueous biological buffer that maintains a stable pH value. Sodium phosphate buffer 0.02 M, pH 6.9 is often used in enzyme activity assays, such as α-amylase assays. Sodium phosphate buffer 0.02 M, pH 6.9 is prepared by mixing disodium hydrogen phosphate (Na2HPO4) (HY-B2243) and sodium dihydrogen phosphate (NaH2PO4) (HY-Y0308) to a total concentration of 0.02 M .
    Sodium phosphate buffer 0.02 M, pH 6.9
  • HY-B1610L
    Sodium Citrate Buffer, 0.5M, pH 6.0
    1 Publications Verification

    		 Biochemical Assay Reagents Others
    Sodium citrate buffer, 0.5M, pH 6.0, is a commonly used buffer with main components are citric acid and sodium hydrogen phosphate. Sodium citrate buffer, 0.5M, pH 6.0 is used for RNA isolation and antigens detection in fixed tissue .
    Sodium Citrate Buffer, 0.5M, pH 6.0
  • HY-10499
    PH-064
    2 Publications Verification

    BIM-46187

    		 Serotonin Transporter Akt Neurological Disease Inflammation/Immunology Cancer
    PH-064 (BIM-46187) is an orally active inhibitor of the heterotrimeric G-protein complex. PH-064 inhibits SERT activity and attenuates shear stress-induced Akt phosphorylation. PH-064 has potent anti-hyperalgesia activity. PH-064 inhibits G protein-coupled receptor-dependent tumorigenesis. PH-064 can be used in the study of pain (e.g., inflammatory pain, neuropathic pain), GPCR-dependent tumors, and inflammatory lung injury .
    PH-064
  • HY-Y0699
    Methyl red

    		Environmental Pollutants Fluorescent Dye Others
    Methyl red is a pH-sensitive acid-base indicator and colorimetric reagent with a pKa of 5.1. Methyl red achieves visual judgment of the titration endpoint through reversible structural changes of protonation (red, pH <4.4) and deprotonation (yellow, pH >6.2). Methyl red is widely used in acid-base titration in chemical analysis and buffer pH monitoring in biochemistry .
    Methyl red
  • HY-145567
    Fasedienol

    pH94B

    		 Calcium Channel Neurological Disease
    Fasedienol (PH94B) is a neurochemical stimulator of the vomeronasal organ (VON). Fasedienol significantly increases Ca ++. Fasedienol modulates the olfactory amygdala circuitry of fear and anxiety to alleviate symptoms of PMS and anxiety .
    Fasedienol
  • HY-D0169A
    Phenol Red sodium salt
    1 Publications Verification

    pHenolsulfonepHthalein sodium salt

    		 Fluorescent Dye Glutathione Peroxidase Others
    Phenol red (Phenolsulfonephthalein) sodium salt is a pH indicator dye. Phenol Red sodium salt is also an antagonist of rat P2X1R. Phenol Red sodium salt enhances the halogenating activity of myeloperoxidase. Phenol Red sodium salt shows a distinct color change from pink to yellow in a positive pH reaction .
    Phenol Red sodium salt
  • HY-12063
    PHT-427
    2 Publications Verification

    		 Akt Apoptosis Cancer
    PHT-247 is an inhibitor of the pleckstrin homology (PH) domain of Akt, and it is also an inhibitor of PDPK1 with Kis of 2.7 µM and 5.2 µM and for Akt and PDPK1, respectively.
    PHT-427
  • HY-141894
    5-Ph-IAA-AM
    2 Publications Verification

    		 Histone Acetyltransferase Metabolic Disease
    5-Ph-IAA-AM is an eggshell-permeable 5-Ph-IAA (HY-134653) analog which contains an acetoxymethyl (AM) group. 5-Ph-IAA-AM affords an enhanced protein degradation in laid embryos. 5-Ph-IAA-AM can be used to disclosure the roles of proteins in C. elegans, in particular those that are involved in embryogenesis and development, through temporally controlled protein degradation .
    5-Ph-IAA-AM
  • HY-130107
    Ald-Ph-NHS ester

    		ADC Linker Cancer
    Ald-Ph-NHS ester is a nonclaevable linker for antibody-agent-conjugation (ADC).
    Ald-Ph-NHS ester
  • HY-179669C
    1M Tris-HCl Buffer, pH 7.6

    		Biochemical Assay Reagents Others
    1M Tris-HCl Buffer, pH 7.6 is a buffer solution commonly used in various biochemical and molecular biological applications to maintain a stable pH environment. The pH value of Tris-HCl changes with temperature; generally, the pH decreases by 0.03 units for every degree Celsius increase in temperature. The pH values indicated on the product are the pH values of the Tris-HCl buffer solution at 25°C.
    1M Tris-HCl Buffer, pH 7.6
  • HY-179669
    1M Tris-HCl Buffer, pH 6.8

    		Biochemical Assay Reagents Others
    1M Tris-HCl Buffer, pH 6.8 is a buffer solution commonly used in various biochemical and molecular biological applications to maintain a stable pH environment. The pH value of Tris-HCl changes with temperature; generally, the pH decreases by 0.03 units for every degree Celsius increase in temperature. The pH values indicated on the product are the pH values of the Tris-HCl buffer solution at 25°C.
    1M Tris-HCl Buffer, pH 6.8
  • HY-D1093
    Carboxy SNARF-1, acetoxymethyl ester (5/6-mixture)

    		Fluorescent Dye Others
    Carboxy SNARF-1, acetoxymethyl ester (5/6-mixture) is a fluorescent probe that is sensitive to pH. Carboxy SNARF-1, acetoxymethyl ester (5/6-mixture) can be used for measurement of intracellular pH .
    Carboxy SNARF-1, acetoxymethyl ester (5/6-mixture)
  • HY-179669I
    1.5M Tris-HCl Buffer, pH 8.8

    		Biochemical Assay Reagents Others
    1M Tris-HCl Buffer, pH 8.8 is a buffer solution commonly used in various biochemical and molecular biological applications to maintain a stable pH environment. The pH value of Tris-HCl changes with temperature; generally, the pH decreases by 0.03 units for every degree Celsius increase in temperature. The pH values indicated on the product are the pH values of the Tris-HCl buffer solution at 25°C.
    1.5M Tris-HCl Buffer, pH 8.8
  • HY-D1457
    DND-189

    		Fluorescent Dye Others
    DND-189, a low-pH fluorescent probe, is sensitive to neutral and low pH range. DND-189 can be used to measure the pH of acidic organelles .
    DND-189
  • HY-160114A
    Potassium phosphate buffer (0.1 M, pH 7.5)

    		Biochemical Assay Reagents Others
    Potassium phosphate buffer (0.1 M, pH 7.5) is a potassium phosphate buffer with a concentration of 0.1 M and a pH of 7.5.
    Potassium phosphate buffer (0.1 M, pH 7.5)
  • HY-P2757
    Phosphorylase kinase

    pHK

    		 Others Others
    Phosphorylase kinase relies on Ca 2+ to exert its activity. Phosphorylase kinase’s sensitivity to Ca 2+ is influenced by its activation state and pH. Phosphorylase kinase can be activated by adrenaline .
    Phosphorylase kinase
  • HY-114457
    Phosphatidylinositol 4,5-bisphosphate

    L-alpHa-pHospHatidylinositol-4,5-bispHospHate; (PtdIns)-(4,5)-P2

    		 Phospholipase Inflammation/Immunology
    Phosphatidylinositol 4,5-bisphosphate (L-alpha-Phosphatidylinositol-4,5-bisphosphate) is a plasma membrane lipid that is enriched in the cytoplasmic leaflet of the plasma membrane. Phosphatidylinositol 4,5-bisphosphate serves as a substrate for phospholipase C and class I PI3K, generating diacylglycerol, inositol (1,4,5)-trisphosphate, and phosphatidylinositol (3,4,5)-trisphosphate. Phosphatidylinositol 4,5-bisphosphate contributes to lamellipodial protrusion, directional cell migration, focal adhesion lipid generation, and trafficking of the GABAA receptor. Phosphatidylinositol 4,5-bisphosphate can be used in research related to acute lung injury and pulmonary edema .
    Phosphatidylinositol 4,5-bisphosphate
  • HY-DY1071
    pH Receptor Probe (solution)

    		Fluorescent Dye Others
    pH Receptor Probe (solution) is a pH-sensitive cyanine derivative and a environmental sensitive fluorophore. pH Receptor Probe has a pH-sensitive maximal absorption at 644 nm and emission at 664 nm. pH Receptor Probe has been used as a pH sensor of lysosomal compartments .
    Solvent and concentration: DMSO: 10 mM
    pH Receptor Probe (solution)
  • HY-149669
    PH14

    		PI3K HDAC Apoptosis Cancer
    PH14 is a dual PI3K/HDAC inhibitor with IC50 values of 20.3 nM and 24.5 nM for PI3Kα and HDAC3, respectively. PH14 has antiproliferative activity and also induces apoptosis in Jeko-1 cells. PH14 can be used in cancer research, such as lymphoma .
    PH14
  • HY-D0265
    Thymolphthalein

    		Environmental Pollutants Fluorescent Dye Others
    Thymolphthalein is an electrochemically active dye due to the presence of thymol fragments. Thymolphthalein is a Phthalein dye used as an acid-base indicator. It is colourless in acid pH and is blue in basic pH .
    Thymolphthalein
  • HY-Y0682I
    0.5M Ethylenediaminetetraacetic acid Solution, pH 8.0

    0.5M EDTA Solution, pH 8.0

    		 Biochemical Assay Reagents Others
    0.5M Ethylenediaminetetraacetic acid Solution, pH 8.0 (0.5M EDTA Solution, pH 8.0) is a commonly used molecular biology reagent used for chelating magnesium ions, etc. This product is prepared using EDTA-Na2 and the pH value is adjusted to 8.0 with NaOH.
    0.5M Ethylenediaminetetraacetic acid Solution, pH 8.0
  • HY-160113E
    Sodium phosphate buffer 0.1M, pH 8.0

    		Biochemical Assay Reagents Others
    Sodium phosphate buffer 0.1M, pH 8.0 is an aqueous sodium phosphate buffer with a concentration of 0.1M and a pH value of 8.0. Sodium phosphate buffer 0.1M, pH 8.0 can be used for the preparation of hydrated micellar membranes, the construction of pH-sensitive nanocarriers, and the maintenance of stable environmental conditions for pH-cleavable PEG-Hz-PE micelles. Sodium phosphate buffer 0.1M, pH 8.0 can also serve as a universal solvent, reaction medium and eluent, and is widely applied in experimental processes such as antibody thiolation, nanoparticle purification and cross-linking reactions .
    Sodium phosphate buffer 0.1M, pH 8.0
  • HY-128545
    Nitrazine yellow

    Nitrazine paper; pHenapHthazine

    		 Biochemical Assay Reagents Others
    Nitrazine yellow (Nitrazine paper; Phenaphthazine) is a pH indicator. The color of Nitrazine yellow changes from yellow to blue in the pH range from 6.0 to 7.0. Nitrazine yellow is a kind of biological materials or organic compounds that are widely used in life science research .
    Nitrazine yellow
  • HY-B0246S3
    Carbamazepine-(Ph)d8

    CBZ-(pH)d8; NSC 169864-(pH)d8

    		 Isotope-Labeled Compounds Neurological Disease Cancer
    Carbamazepine-(Ph)d8 (CBZ-(Ph)d8; NSC 169864-(Ph)d8) is the deuterium labeled Carbamazepine-(Ph) (HY-B0246) .
    Carbamazepine-(Ph)d8
  • HY-124480
    Tetrazine-Ph-acid

    		PROTAC Linkers Cancer
    Tetrazine-Ph-acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-acid is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
    Tetrazine-Ph-acid
  • HY-179669E
    1M Tris-HCl Buffer, pH 8.0

    		Biochemical Assay Reagents Others
    1M Tris-HCl Buffer, pH 8.0 is a buffer solution commonly used in various biochemical and molecular biological applications to maintain a stable pH environment. The pH value of Tris-HCl changes with temperature; generally, the pH decreases by 0.03 units for every degree Celsius increase in temperature. The pH values indicated on the product are the pH values of the Tris-HCl buffer solution at 25°C.
    1M Tris-HCl Buffer, pH 8.0
  • HY-179669A
    1M Tris-HCl Buffer, pH 7.0

    		Biochemical Assay Reagents Others
    1M Tris-HCl Buffer, pH 7.0 is a buffer solution commonly used in various biochemical and molecular biological applications to maintain a stable pH environment. The pH value of Tris-HCl changes with temperature; generally, the pH decreases by 0.03 units for every degree Celsius increase in temperature. The pH values indicated on the product are the pH values of the Tris-HCl buffer solution at 25°C.
    1M Tris-HCl Buffer, pH 7.0
  • HY-126908
    Tetrazine-Ph-NHS ester

    		PROTAC Linkers Cancer
    Tetrazine-Ph-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
    Tetrazine-Ph-NHS ester
  • HY-153395
    PH-HG-005-5

    		Drug-Linker Conjugates for ADC Cancer
    PH-HG-005-5 (compound 16c) is a derivative of SN-38 (HY-13704) and can be used as Drug-Linker Conjugates for ADC. PH-HG-005-5 can conjugate to targeting peptides for ADCs synthesis .
    PH-HG-005-5
  • HY-D0252
    m-Cresol purple

    		Fluorescent Dye Others
    m-Cresol purple is a pH indicator dye with large cross section and halochromic property in neutral pH range .
    m-Cresol purple
  • HY-151797
    Ph-HTBA

    		CaMK Neurological Disease
    Ph-HTBA is a high-affinity, brain-penetrating modulator for CaMKIIα. Ph-HTBA has binding affinity for CaMKIIα with a Kd value of 757 nM. Ph-HTBA can be used for the research of ischemia and neurodegenerative disorders .
    Ph-HTBA
  • HY-141808
    AZD-CO-Ph-PEG4-Ph-CO-AZD

    		Beta-lactamase Cancer
    AZD-CO-Ph-PEG4-Ph-CO-AZD is a bis-β-lactam linker can be used for antibody-siRNA conjugate synthesis .
    AZD-CO-Ph-PEG4-Ph-CO-AZD
  • HY-179669H
    1M Tris-HCl Buffer, pH 8.8

    		Biochemical Assay Reagents Others
    1M Tris-HCl Buffer, pH 8.8 is a buffer solution commonly used in various biochemical and molecular biological applications to maintain a stable pH environment. The pH value of Tris-HCl changes with temperature; generally, the pH decreases by 0.03 units for every degree Celsius increase in temperature. The pH values indicated on the product are the pH values of the Tris-HCl buffer solution at 25°C.
    1M Tris-HCl Buffer, pH 8.8
  • HY-179669J
    1.5M Tris-HCl Buffer, pH 6.8

    		Biochemical Assay Reagents Others
    1M Tris-HCl Buffer, pH 6.8 is a buffer solution commonly used in various biochemical and molecular biological applications to maintain a stable pH environment. The pH value of Tris-HCl changes with temperature; generally, the pH decreases by 0.03 units for every degree Celsius increase in temperature. The pH values ??indicated on the product are the pH values ??of the Tris-HCl buffer solution at 25°C.
    1.5M Tris-HCl Buffer, pH 6.8
  • HY-128590
    PHT-7.3
    1 Publications Verification

    		 Ras Cancer
    PHT-7.3 is a selective inhibitor of connector enhancer of kinase suppressor of Ras 1 (Cnk1) pleckstrin homology (PH) domain (Kd=4.7 μM). PHT-7.3 inhibits mut-KRas, but not wild-type KRas cancer cell and tumor growth and signaling. PHT-7.3 has antitumor activity .
    PHT-7.3
  • HY-179667
    PH calibration buffer, pH 4.01

    		Biochemical Assay Reagents Others
    PH calibration buffer (pH 4.01) is a pH calibration buffer with a pH value of 4.01.
    PH calibration buffer, pH 4.01
  • HY-130928
    Tetrazine-Ph-OPSS

    		ADC Linker Cancer
    Tetrazine-Ph-OPSS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-Ph-OPSS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
    Tetrazine-Ph-OPSS
  • HY-W576870
    Hydrouracil-3-Ph-COOH

    		Ligands for E3 Ligase Cancer
    Hydrouracil-3-Ph-COOH is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Hydrouracil-3-Ph-COOH can be linked to a target protein ligand via a linker to form a PROTAC.
    Hydrouracil-3-Ph-COOH

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