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polymeric

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1363

Inhibitors & Agonists

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GMP Molecules

PEG300 Maximum Cited Publications 178 Publications Verification Polyethylene glycol 300	Environmental Pollutants Biochemical Assay Reagents	Others
PEG300 (Polyethylene glycol 300), a neutral polymer of molecular weight 300, is a water-soluble, low immunogenic and biocompatible polymer formed by repeating units of ethylene glycol .

PEG3350 Polyethylene glycol 3350	Environmental Pollutants Biochemical Assay Reagents	Others
PEG3350 (Polyethylene glycol 3350) a neutral polymer of molecular weight 3350. PEG3350 used as an excellent solvent for a large number of substances.

RuPhos	Biochemical Assay Reagents	Others
RuPhos is a Buchwald ligand. In aqueous Suzuki-Miyaura catalytic transfer polymerization, RuPhos forms inactive Pd (RuPhos)₂ with palladium and inhibits diffusion to improve polymerization controllability. RuPhos additional addition in anhydrous Kumada polymerization exacerbates catalyst deactivation and chain transfer, significantly impairing polymerization control .

Poloxamer 105 (L35) PEG-PPG-PEG, 1900 (Average)	Environmental Pollutants Biochemical Assay Reagents	Others
Poloxamer 105 L35 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 1900 Da. Poloxamer 105 L35 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

2-Hydroxyethyl methacrylate	Biochemical Assay Reagents	Others
2-Hydroxyethyl methacrylate (HEMA) is a monomer used in the synthesis of various polymers, and the polymer PHEMA of 2-Hydroxyethyl methacrylate is widely used in the synthesis of dental composite materials .

PVA (Mw 145000, 99+% hydrolyzed, ~3300 polymerization) 1 Publications Verification Polyvinyl alcohol (Mw 145000, 99+% hydrolyzed, ~3300 polymerization); Poly(Ethenol) (Mw 145000, 99+% hydrolyzed, ~3300 polymerization)	Biochemical Assay Reagents	Others
PVA (Mw 145000, 99+% hydrolyzed, ~3300 polymerization) is a polyvinyl alcohol with molecular weight of 145000 with hydrolysis properties. PVA (Mw 145000, 99+% hydrolyzed, ~3300 polymerization) is obtained by polymerizing vinyl acetate followed by hydrolysis to remove acetate groups, yielding polyvinyl alcohol .

3-Glycidyloxypropyltrimethoxysilane GPTMS	Biochemical Assay Reagents	Others
3-Glycidyloxypropyltrimethoxysilane (GPTMS) is a silicon source for the preparation of inorganic-organic hybrid polymers. 3-Glycidyloxypropyltrimethoxysilane can be used to prepare hard coatings of organic polymers, such as contact lens materials in the optical industry, as well as related materials in the fields of electronics, thin films, sensors, nanoimprinting, waveguides, and biology .

Norbornene	Ligands for E3 Ligase	Others
Norbornene is a cycloolefin and building block for synthesis of porous organic polymeric materials via metathesis, addition, and CANAL polymerization. Norbornene can also be used as an E3 ligase ligand for the synthesis of PROTAC, such as PROTAC HyTTD Degrader-1 (HY-181895) .

Methacrylic acid N-hydroxysuccinimide ester NHS-MA	Biochemical Assay Reagents	Others
Methacrylic acid N-hydroxysuccinimide ester (NHS-MA) is a polymer that serves as a monomer to prepare degradable amphiphilic block copolymer microparticles via RAFT polymerization for low pH-triggered drug delivery. Methacrylic acid N-hydroxysuccinimide ester is used for the synthesis of nanogels .

Bis(4-nitrophenyl) phosphate	Biochemical Assay Reagents	Others
Bis(4-nitrophenyl) phosphate is a catalyst for metal micelles and can catalyze the hydrolysis of (4-nitrophenyl) phosphate. Bis(4-nitrophenyl) phosphate is also an effective catalyst for ring-opening polymerization (ROP), which can achieve controlled polymerization of β-butyrolactone (β-BL) ring-opening and can be used to prepare diembedded polymers without quenching. segment copolymer .

HPMC (Type II,Viscosity:3mPa.s) Hypromellose (Type II,Viscosity:3mPa.s); (Hydroxypropyl)methyl cellulose (Type II,Viscosity:3mPa.s); Celacol HPM 5000 (Type II,Viscosity:3mPa.s)	Environmental Pollutants Biochemical Assay Reagents	Others
HPMC (Type II, Viscosity: 3 mPa.s) is a nonionic polymer prepared via synthetic modification of cellulose. As a hydrophilic matrix material, HPMC prolongs drug release through non-Fickian diffusion, which includes the diffusion of drugs in the hydrated matrix and the polymer relaxation process .

Fluorescein O-methacrylate Methacryloyloxy fluorescein	Fluorescent Dye	Others
Fluorescein O-methacrylate (Methacryloyloxy fluorescein) is a pH-responsive fluorescent monomeric dye. Fluorescein O-methacrylate exhibits pH-responsive fluorescence properties: its fluorescence is activated under alkaline conditions and quenched under neutral or acidic conditions; reversible switching of fluorescence is achievable by adjusting the pH of the solution. Fluorescein O-methacrylate can be used as a monomer for the synthesis of amphiphilic fluorescein polymers. These polymers can self-assemble into stable polymer nanoparticles with enhanced aqueous-phase fluorescence, and also enable the conjugation of nanoparticles with amine-containing biomolecules to support sensitive optical detection of biomarkers (Ex/Em = 490/520 nm) .

Ethylene glycol diacrylate Ethylene diacrylate	Biochemical Assay Reagents	Others
Ethylene glycol diacrylate (Ethylene diacrylate) is a polymer precursor used to form covalently crosslinked hydrogels with a degree of polymerization of 13 .

Poly(ethylene glycol) dithiol (Mn 3400)	Biochemical Assay Reagents	Others
Poly(ethylene glycol) dithiol (Mn 3400) is a polymer and can be used as a biomaterial to prepare hydrogels .

Cellohexaose	Endogenous Metabolite	Metabolic Disease
Cellohexaose is a glucose polymer with two or more glucose monomers produced from the breakdown of cellulose, consisting of a condensation of beta (1-4) linked D-glucose monomers .

2-Vinylnaphthalene 2-Ethenylnaphthalene; 2-Vinylnaphthalene	Biochemical Assay Reagents	Others
2-Vinylnaphthalene (2-Ethenylnaphthalene; 2-Vinylnaphthalene) is an organic polymer. 2-Vinylnaphthalene is a kind of biological materials or organic compounds that are widely used in life science research .

PVA (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization) Polyvinyl alcohol (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization); Poly(Ethenol) (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization)	Biochemical Assay Reagents	Others
PVA (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization) (Polyvinyl alcohol (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization); Poly(Ethenol) (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization)) is a biodegradable of polymer. PVA (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization) can be used to blend with various biopolymers and hydrophilic synthetic polymers to improve mechanical properties of films .

PVA (Mw 61000, 98-99% hydrolyzed, ~1400 polymerization) Polyvinyl alcohol (Mw 61000, 98-99% hydrolyzed, ~1400 polymerization); Poly(Ethenol) (Mw 61000, 98-99% hydrolyzed, ~1400 polymerization)	Biochemical Assay Reagents	Others
PVA (Mw 61000, 98-99% hydrolyzed, ~1400 polymerization) (Polyvinyl alcohol (Mw 61000, 98-99% hydrolyzed, ~1400 polymerization); Poly(Ethenol) (Mw 61000, 98-99% hydrolyzed, ~1400 polymerization)) is a biodegradable of polymer. PVA (Mw 61000, 98-99% hydrolyzed, ~1400 polymerization) can be used to produce bio-composite films .

PVA (Mw 195000, 98-99% hydrolyzed, ~4300 polymerization) Polyvinyl alcohol (Mw 195000, 98-99% hydrolyzed, ~4300 polymerization); Poly(Ethenol) (Mw 195000, 98-99% hydrolyzed, ~4300 polymerization)	Biochemical Assay Reagents	Others
PVA (Mw 195000, 98-99% hydrolyzed, ~4300 polymerization) is polyvinyl alcohol with a molecular weight of 195,000 and hydrolytic properties. PVA (Mw 195000, 98-99% hydrolyzed, ~4300 polymerization) is obtained by polymerizing vinyl acetate followed by hydrolysis to remove acetate groups, yielding polyvinyl alcohol .

PLGA38000-PEG10000 1 Publications Verification	Biochemical Assay Reagents	Others
PLGA38000-PEG10000 is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .

PVA (Mw 31000, 87-89% hydrolyzed, ~630 polymerization) Polyvinyl alcohol (Mw 31000, 87-89% hydrolyzed, ~630 polymerization); Poly(Ethenol) (Mw 31000, 87-89% hydrolyzed, ~630 polymerization)	Biochemical Assay Reagents	Others
PVA (Mw 31000, 87-89% hydrolyzed, ~630 polymerization) (Polyvinyl alcohol (Mw 31000, 87-89% hydrolyzed, ~630 polymerization); Poly(Ethenol) (Mw 31000, 87-89% hydrolyzed, ~630 polymerization)) is a biocompatible, biodegradable, nontoxic and hydrophilic synthetic polymer. PVA (Mw 31000, 87-89% hydrolyzed, ~630 polymerization) can be used to produce bone tissue engineering scaffold ^[1]

PVA (Mw 47000, 98-99% hydrolyzed, ~1000 polymerization) Polyvinyl alcohol (Mw 47000, 98-99% hydrolyzed, ~1000 polymerization); Poly(Ethenol) (Mw 47000, 98-99% hydrolyzed, ~1000 polymerization)	Biochemical Assay Reagents	Others
PVA (Mw 47000, 98-99% hydrolyzed, ~1000 polymerization) is a polyvinyl alcohol with molecular weight of 47000 with hydrolysis properties. Hydrolysis degree refers to the conversion rate of acetic acid group hydrolysis to hydroxyl group in the original polyvinyl acetate, PVA (Mw 47000, 98-99% hydrolyzed, ~1000 polymerization). In addition, polyvinyl alcohol is obtained from polymerization of vinyl acetate to remove acetic acid group by hydrolysis. Polyvinyl alcohol with different degrees of hydrolysis can be self-crosslinked to form frozen gels and used as biological excipients .

Poloxamer 125 (L45) PEG-PPG-PEG, 2400 (Average)	Biochemical Assay Reagents	Others
Poloxamer 125 L45 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 2400. Poloxamer 125 L45 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

mPEG-PLGA	Biochemical Assay Reagents	Others
mPEG-PLGA is a mucus-penetrating polymer. mPEG-PLGA is a raw material to prepare nanomedicine .

Tubulin polymerization-IN-29	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-29 (compound 6g) is a potent tubulin polymerization inhibitor. Tubulin polymerization-IN-29 exhibits potent antiproliferative activity. Tubulin polymerization-IN-29 can induce HeLa cells arrest in G2/M phase .

Dansyl ethylenediamine	Fluorescent Dye	Others
Dansyl ethylenediamine is a fluorescent probe. Dansyl ethylenediamine can be used for synthesis of protein-imprinted polymers which is capable of specific transduction of protein binding events into fluorescent signal change .

Tubulin polymerization-IN-25	Microtubule/Tubulin Farnesyl Transferase	Cancer
Tubulin polymerization-IN-25 (compound 17f) is a dual inhibitor of tubulin polymerization and farnesyl transferase (FTase) with IC₅₀s of 1.11 μM and 0.39 μM, respectively. Tubulin polymerization-IN-25 displays cytotoxicity and excellent antitumor activity .

PLGA10000-PEG3000-VS PLGA10000-PEG3000-Vinylsulfone	Biochemical Assay Reagents	Others
PLGA10000-PEG3000-VS (PLGA10000-PEG3000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .

Tubulin polymerization-IN-7	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-7 (compound 5) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-7 has the potential for the research of cancer diseases .

Tubulin polymerization-IN-3	Microtubule/Tubulin Apoptosis	Cancer
Tubulin polymerization-IN-3 (compound 4c) is a potent tubulin polymerization inhibitor, with an IC₅₀ of 3.84 µM. Tubulin polymerization-IN-3 can induce apoptosis in colon cancer cells .

Tubulin polymerization-IN-80	Microtubule/Tubulin Apoptosis	Cancer
Tubulin polymerization-IN-80 (Compound 32) is a potent tubulin polymerization inhibitor with antiproliferative activity. Tubulin polymerization-IN-80 disrupts microtubule formation and leads to cell cycle arrest and apoptosis. Tubulin polymerization-IN-80 is promising for research of cancers .

Tubulin polymerization-IN-17	Microtubule/Tubulin Apoptosis	Cancer
Tubulin polymerization-IN-17 (compound 23g) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-17 exhibits tubulin depolymerization and induced cell apoptosis and inhibits migration. Tubulin polymerization-IN-17 has the potential for the research of cancer diseases .

Tubulin polymerization-IN-20	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-20 (compound 11) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-20 has the potential for the research of breast cancers and chemoresistant colon cancers .

Tubulin polymerization-IN-19	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-19 (compound 4) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-20 has the potential for the research of breast cancers and chemoresistant colon cancers .

Tubulin polymerization-IN-18	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-18 (compound 8) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-18 has the potential for the research of breast cancers and chemoresistant colon cancers .

Tubulin polymerization-IN-15	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-15 (compound 4) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-15 has the potential for the research of cancer diseases .

Tubulin polymerization-IN-14	Microtubule/Tubulin Apoptosis	Cancer
Tubulin polymerization-IN-14 (Compound 20a) is a tubulin polymerization inhibitor with an IC₅₀ of 3.15 μM. Tubulin polymerization-IN-14 shows potent anti-vascular and anticancer activities, induces cancer cell apoptosis .

Tubulin polymerization-IN-39	Microtubule/Tubulin	Cardiovascular Disease Cancer
Tubulin polymerization-IN-39 is a tubulin polymerization inhibitor (IC₅₀: 4.9 μM). Tubulin polymerization-IN-39 occupies the colchicine-binding site. Tubulin polymerization-IN-39 inhibits cancer cell proliferation .

Tubulin polymerization-IN-58	Microtubule/Tubulin YAP	Cancer
Tubulin polymerization-IN-58 (Compound K18) is a tubulin polymerization inhibitor with an IC₅₀ of 0.446 μM. Tubulin polymerization-IN-58 also induces the degradation of oncogenic protein YAP via the UPS pathway, thus can be used for cancer research .

Tubulin polymerization-IN-8	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-8 (compound IIc) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-8 concentration-dependently causes cell cycle arrest at the G2/M phase in HCT116 tumor cells, and displays a significant inhibition of tubulin polymerization with an IC₅₀ value of 12.7 μM. Tubulin polymerization-IN-8 has the potential for the research of cancer diseases ^{[ 1]}.

Tubulin polymerization-IN-49	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-49 (compound 12d) is a potent tubulin polymerization inhibitor. Tubulin polymerization-IN-49 bound to colchicine site on tubulin and inhibited tubulin polymerization. Tubulin polymerization-IN-49 induces cell cycle arrest at G2/M phase and apoptosis. Tubulin polymerization-IN-49 has anticancer active and prevents tumor generation, inhibits tumor proliferation and angiogenesis .

Tubulin polymerization-IN-21	Microtubule/Tubulin	Metabolic Disease Cancer
Tubulin polymerization-IN-21 (compound 9a) is a tubulin polymerization inhibitor. Tubulin polymerization-IN-21 exhibits anti-cancer activity through disrupting cellular integrity and affecting glucose metabolism .

Tubulin polymerization-IN-43	Microtubule/Tubulin Apoptosis	Cancer
Tubulin polymerization-IN-43 (compound 15h) is a tubulin polymerization inhibitor. Tubulin polymerization-IN-43 disrupts cellular microtubule networks by targeting the Colchicine (HY-16569) site, and promots cell cycle arrest of leukemia cells at G2/M phase and cell apoptosis, as well as inhibiting angiogenesis .

Tubulin polymerization-IN-22	Microtubule/Tubulin Apoptosis	Cancer
Tubulin polymerization-IN-22 is a tubulin polymerization inhibitor with an IC₅₀ of 8.1 μM. Tubulin polymerization-IN-22 arrests cell cycle at G2/M phase and induces apoptosis .

Tubulin polymerization-IN-16	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-16 (compound 5g) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-16 shows most potent against cancer cells, with IC₅₀ values of 0.084-0.221 μM. Tubulin polymerization-IN-16 potently disrupts microtubule/tubulin dynamics, induces cell cycle arrest at G2/M phase in SGC-7901 cells .

6,7-Epoxy-latrunculin A 6,7-Epoxy-LAT-A	Arp2/3 Complex	Others
6,7-Epoxy-latrunculin A can be isolated from the Red Sea sponge Negombata magnifica and is initially identified as an inhibitor of actin polymerization by its morphological effects .

Cat. No.	Product Name

HY-L0103V

UORSY Screening Library	680,000 compounds
UORSY Screening Compounds Library contains about 680,000 compounds. The library has extensively developed a polymerization synthesis method that provides a highly diverse chemical structure. More than 85% of the compounds in the library have drug-like physicochemical properties, and more than 35% of the compounds have lead-like properties.

HY-L060

Cytoskeleton Compound Library

2,148 compounds

The cytoskeleton is responsible for contraction, cell motility, movement of organelles and vesicles through the cytoplasm, cytokinesis, intracellular signal transduction, and many other functions that are essential for cellular homeostasis and survival. It accomplishes these tasks through three basic structures: F-actin, microtubules, and intermediate filaments (IFs). The cytoskeleton is a dynamic structure where the three major filaments and tubules are under the influence of proteins that regulate their length, state of polymerization, and level of cross-linking. Since cytoskeleton is involved in virtually all cellular processes, cytoskeletal protein aberrations are the underlying reason for many pathological phenotypes, including several cardiovascular disease syndromes, neurodegeneration, cancer, liver cirrhosis, pulmonary fibrosis, and blistering skin diseases.

MCE designs a unique collection of 2,148 cytoskeleton-related compounds mainly focusing on the key targets in the cytoskeleton signal pathway and can be used in the research of cytoskeleton signal pathway and related diseases.

HY-L175

Inflammasomes related Compound Library

163 compounds

Inflammasomes are classic pattern recognition receptors for natural immune responses. Inflammasomes are polymeric protein complexes that regulate inflammatory responses and pyrolytic cell death, thereby exerting the host's defense against microorganisms. Inflammasomes sensors are associated with adapter proteins, activating inflammatory caspase-1, releasing inflammatory cytokines and inducing cell death, endowing the host with defense against pathogens. NLRP1, NLRP3, NLRC4, AIM2, and pyrin are considered typical inflammasomes because they convert cysteine asparaginase-1 into catalytically active capsaicin-1. In addition to infectious diseases, the importance of inflammasomes is also related to various clinical diseases, such as autoimmune diseases, neurodegeneration and metabolic disorders, and the development of cancer. Therefore, it is necessary to strictly regulate the activation and function of inflammasomes to avoid accidental host tissue damage while inducing pathogens to kill the inflammatory response.

MCE designs a unique collection of 163 inflammasomes related compounds. It is a good tool to be used for research on Inflammation, cancer and other diseases.

Cat. No.	Product Name	Type

HY-15534

JC-1

Maximum Cited Publications

212 Publications Verification

CBIC2

Fluorescent Dyes

JC-1 (CBIC2) is an ideal fluorescent probe widely used to detect mitochondrial membrane potential. JC-1 accumulates in mitochondria in a potential dependent manner and can be used to detect the membrane potential of cells, tissues or purified mitochondria. In normal mitochondria, JC-1 aggregates in the mitochondrial matrix to form a polymer, which emits strong red fluorescence (Ex=585 nm, Em=590 nm); When the mitochondrial membrane potential is low, JC-1 cannot aggregate in the matrix of mitochondria and produce green fluorescence (ex=510 nm, em= 527 nm) .

HY-164153

ADC Control Human IgG1-vcMMAE (solution)	Fluorescent Dyes
ADC Control Human IgG1-vcMMAE (solution) is a humanized monoclonal antibody that is an isotype control of ADC human IgG1-vcMMAE and can inhibit tubulin polymerization. The antibody portion is Human IgG1 kappa, Isotype Control (HY-P99001), and the drug-linker conjugate for ADC is vcMMAE (HY-15575) .

HY-15162G

Monomethyl auristatin E MMAE; SGD-1010; Vedotin	Fluorescent Dyes
Monomethyl auristatin E (MMAE) (GMP) is Monomethyl auristatin E (HY-15162) produced by using GMP guidelines. Monomethyl auristatin E is a tubulin polymerization inhibitor .

HY-DY1003

JC-1 (solution)

Fluorescent Dyes

JC-1 (CBIC2) (solution) is an ideal fluorescent probe widely used to detect mitochondrial membrane potential. JC-1 accumulates in mitochondria in a potential dependent manner and can be used to detect the membrane potential of cells, tissues or purified mitochondria. In normal mitochondria, JC-1 aggregates in the mitochondrial matrix to form a polymer, which emits strong red fluorescence (Ex=585 nm, Em=590 nm) ; When the mitochondrial membrane potential is low, JC-1 cannot aggregate in the matrix of mitochondria and produce green fluorescence (ex=510 nm, em= 527 nm) .
Solvent and concentration: DMSO: 1.5 mM

HY-W923198

Fluorescein O-methacrylate

Methacryloyloxy fluorescein

Fluorescent Dyes

Fluorescein O-methacrylate (Methacryloyloxy fluorescein) is a pH-responsive fluorescent monomeric dye. Fluorescein O-methacrylate exhibits pH-responsive fluorescence properties: its fluorescence is activated under alkaline conditions and quenched under neutral or acidic conditions; reversible switching of fluorescence is achievable by adjusting the pH of the solution. Fluorescein O-methacrylate can be used as a monomer for the synthesis of amphiphilic fluorescein polymers. These polymers can self-assemble into stable polymer nanoparticles with enhanced aqueous-phase fluorescence, and also enable the conjugation of nanoparticles with amine-containing biomolecules to support sensitive optical detection of biomarkers (Ex/Em = 490/520 nm) .

HY-D1098

SYBR Green II 3 Publications Verification	Fluorescent Dyes
SYBR Green II is a fluorescent nucleic acid dye that mainly binds single-stranded nucleotides. SYBR Green II is sensitive to oligonucleotides or larger nucleic acid polymers in a variety of cells and gels. SYBR Green II can be used to study cell structure, membrane integrity or function, and cell cycle distribution. Wavelength 484/515 nm .

HY-164154

ADC Control Human IgG1-vcMMAF	Fluorescent Dyes
ADC Control Human IgG1-vcMMAF is a humanized monoclonal antibody that is an isotype control of ADC human IgG1-vcMMAF and can inhibit tubulin polymerization. The antibody portion is Human IgG1 kappa, Isotype Control (HY-P99001), and the drug-linker conjugate for ADC is MC-Val-Cit-PAB-MMAF (vcMMAF; HY-112786) .

HY-W440914

DSPE-PEG1000-FITC	Fluorescent Dyes
DSPE-PEG1000-FITC is an amphiphile PEG polymer which has unsaturated lipid tails. The polymer can form micelles in an aqueous solution and can be used to prepare liposome/nano particles for drug nanocarriers. . Reagent grade, for research use only.

HY-D1321A

Cy 5 amine TFA 1 Publications Verification Cyanine5 amine TFA	Fluorescent Dyes
Cy 5 amine (Cyanine5 amine) TFA is a fluorescent dye. Cy 5 amine TFA can be used in the preparation of Cy5.5-labeled compound or polymers, which can be used for imaging cellular process and trafficking .

HY-W440916

DSPE-PEG3400-FITC	Fluorescent Dyes
DSPE-PEG3400-FITC is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.

HY-W440914B

DSPE-PEG10000-FITC	Fluorescent Dyes
DSPE-PEG10000-FITC is an amphiphile PEG polymer which has unsaturated lipid tails. DSPE-PEG10000-FITC can form micelles in an aqueous solution and can be used to prepare liposome/nano particles for drug nanocarriers .

HY-131010

Flutax-2 (5/6-mixture)	Fluorescent Dyes
Flutax-2 (5/6-mixture) is an active fluorescent derivative of paclitaxel. Flutax-2 (5/6-mixture) binds to a polymerized α,β tubulin dimer. Excitation/emission wavelength: 496/524 nm. Paclitaxel, a diterpenoid secondary metabolite produced by Taxus species, can be used for the research of a variety of cancers .

HY-D2004

ATTO 488 streptavidin

Fluorescent Dyes

ATTO 488 streptavidin is a fluorescent reagent that specifically targets and binds to biotin (biotin), formed by the conjugation of ATTO 488 with streptavidin (HY-P3152). ATTO 488 streptavidin enables visualization of the activity of streptavidin immobilized on the surface of polymeric nanoparticles, or acts as a fluorescent probe to detect the selective binding and internalization process of anti-HB-EGF/NA with cells expressing HB-EGF (with no such effect on cells that do not express this receptor). ATTO 488 streptavidin effectively verifies the function of streptavidin conjugated to the surface of nanoparticles and is suitable for research related to atherosclerotic cardiovascular diseases .

HY-15579G

MMAF

Monomethylauristatin F

Fluorescent Dyes

MMAF (Monomethylauristatin F) GMP is a GMP grade MMAF (HY-15579). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. MMAF (Monomethylauristatin F) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF (Monomethylauristatin F) is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as vorsetuzumab mafodotin and SGN-CD19A .

HY-W923645

Fluorescein O,O′-diacrylate

Diacryloyloxyfluorescein

Fluorescent Dyes

Fluorescein O,O′-diacrylate (Diacryloyloxyfluorescein) is a fluorescent compound with good biocompatibility and cell labeling ability. Fluorescein O,O′-diacrylate is often used in biological imaging and cell tracking research, and can effectively label cells and track their dynamic changes in vivo. Fluorescein O,O′-diacrylate is also used in compound delivery systems to improve the localization accuracy and inhibitory effect of compounds. Fluorescein O,O′-diacrylate is also used to prepare polymer materials to enhance their optical properties and biological interactions.

HY-D1098A

SYBR Green II (Ionic form)	Fluorescent Dyes
SYBR Green II (Ionic form) is a fluorescent nucleic acid dye that mainly binds single-stranded nucleotides. SYBR Green II is sensitive to oligonucleotides or larger nucleic acid polymers in a variety of cells and gels. SYBR Green II can be used to study cell structure, membrane integrity or function, and cell cycle distribution. Wavelength 484/515 nm .

HY-W440914C

DSPE-PEG600-FITC	Fluorescent Dyes
DSPE-PEG600-FITC is an amphiphile PEG polymer which has unsaturated lipid tails. DSPE-PEG600-FITC can form micelles in an aqueous solution and can be used to prepare liposome/nano particles for drug nanocarriers (Ex/Em=488/525 nm) .

HY-15578G

McMMAF Maleimidocaproyl monomethylauristatin F	Fluorescent Dyes
McMMAF GMP is a GMP grade McMMAF (HY-15578). McMMAF is a protective group (maleimidocaproyl)-conjugated MMAF, which is a potent tubulin polymerization inhibitor. McMMAF can be used as a agent-linker for antibody-drug conjugates (ADC). McMMAF is uncleavable, and must be internalized and degraded within a cell, releasing cysteine-McMMAF as the active agent .

HY-100374G

Val-Cit-PAB-MMAE	Fluorescent Dyes
Val-Cit-PAB-MMAE GMP is a GMP grade Val-Cit-PAB-MMAE (HY-100374). Val-Cit-PAB-MMAE is a agent-linker conjugate for ADC. Val-Cit-PAB-MMAE contains the ADCs linker (peptide Val-Cit-PAB) and a potent tubulin inhibitor MMAE (HY-15162). MMAE a potent mitotic inhibitor by inhibiting tubulin polymerization.

HY-W321446

Dansyl ethylenediamine	Fluorescent Dyes
Dansyl ethylenediamine is a fluorescent probe. Dansyl ethylenediamine can be used for synthesis of protein-imprinted polymers which is capable of specific transduction of protein binding events into fluorescent signal change .

HY-W440914A

DSPE-PEG400-FITC	Fluorescent Dyes
DSPE-PEG400-FITC is an amphiphile PEG polymer which has unsaturated lipid tails. DSPE-PEG400-FITC can form micelles in an aqueous solution and can be used to prepare liposome/nano particles for drug nanocarriers .

HY-D1545

Violamine R

Acid Violet 9

Fluorescent Dyes

Violamine R (Acid Violet 9) is a potent fluorophore. Violamine R shows environment and temperature-dependent photoluminescence (PL) intermittency in poly(vinyl alcohol) (PVOH) and potassium acid phthalate (KAP). Violamine R can be used to measure the temperatures spanning the glass-transition temperature (Tg) of the polymer host by the fluorescence intermittency or blinking in poly(vinyl alcohol) (PVA) .

HY-D2436

PTX-PEG-Cy3

Fluorescent Dyes

PTX-PEG-Cy3 (Paclitaxel-PEG-Cy3) is a Cy3 (HY-D0822) labeled PTX-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. PTX stabilizes tubulin polymerization. PTX can cause both mitotic arrest and apoptotic cell death. PTX also induces autophagy .

HY-D2422B

Cy5-Paclitaxel

Fluorescent Dyes

Cy5-Paclitaxel is a Cyanine5 carboxylic acid bromide (HY-D1319) labeled Paclitaxel (HY-B0015) conjugate. Cyanine5 carboxylic acid bromide is a fluorescent dye containing a non-activated carboxylic acid (Ex=646 nm, Em=662 nm) that can be used for molecular labeling and microscopy imaging. Paclitaxel stabilizes tubulin polymerization. Paclitaxel can cause both mitotic arrest and apoptotic cell death. Paclitaxel also induces autophagy .

HY-172820

Trastuzumab envedotin

DP303c

Fluorescent Dyes

Trastuzumab envedotin (DP303c) is a anti-human epidermal growth factor receptor 2 (HER2) antibody-drug conjugate (ADC). Trastuzumab envedotin is composed of the tubulin polymerization inhibitor Monomethyl auristatin E (MMAE) (HY-15162) to the anti-HER2 antibody DP001 via a cleavable linker. Trastuzumab envedotin can be used for the research of HER2-positive solid tumors, such as breast cancer, colorectal cancer, and gastric cancer .

HY-119987

Sudan orange G SOG	Fluorescent Dyes
Sudan orange G is an azo dye. Sudan orange G, after enzymatic oxidation, generates oligomers and even polymers through free radical coupling reactions .

HY-119987R

Sudan orange G (Standard) SOG (Standard)	Fluorescent Dyes
Sudan orange G (Standard) is the analytical standard of Sudan orange G. This product is intended for research and analytical applications. Sudan orange G is an azo dye. Sudan orange G, after enzymatic oxidation, generates oligomers and even polymers through free radical coupling reactions .

HY-D2429

Dextran-PEG-Cy3	Fluorescent Dyes
Dextran-PEG-Cy3 is the Cy3 (HY-D0822)-labeled Dextran-PEG conjugate. Dextran-PEG is used as polymer-polymer systems for the high biocompatibility to maintain cell osmolarity. Dextran-PEG coatings can reduce nanoparticle cytotoxicity .

HY-15582G

Auristatin E	Fluorescent Dyes
Auristatin E (GMP) is Auristatin E (HY-15582) produced by using GMP guidelines. Auristatin E is a tubulin polymerization inhibitor .

HY-138111

4-Nitrophenyl β-D-cellotetraoside

p-Nitopheyl β-D-cellotetaoside

Fluorescent Dyes

4-Nitrophenyl β-D-cellotetraoside (p-Nitopheyl β-D-cellotetaoside) is a small molecule cellulose mimetic consisting of a tetramer of D-glucose units linked by β-1-4 glycosidic bonds. The fragmentation pattern of 4-Nitrophenyl β-D-cellotetraoside after enzymatic hydrolysis can be analyzed by TLC or by the release of 4-nitrophenol, which has a strong absorbance at 395 nm in alkaline solutions. 4-Nitrophenyl β-D-cellotetraoside can be used in cellulose degradation studies to determine the specificity of cellulases .

HY-15579BG

MMAF sodium Monomethylauristatin F sodium	Fluorescent Dyes
MMAF sodium GMP is a GMP grade MMAF (sodium) (HY-15579B). MMAF sodium (Monomethylauristatin F sodium) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF sodium (Monomethylauristatin F sodium) is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A .

HY-78931G

Boc-Dap-NE	Fluorescent Dyes
Boc-Dap-NE (GMP) is Boc-Dap-NE (HY-78931) produced by using GMP guidelines. Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.

HY-D2422C

Cy5-Paclitaxel bromide

Fluorescent Dyes

Cy5-Paclitaxel bromide is the bromide of Cy5-Paclitaxel (HY-D2422B). Cy5-Paclitaxel is a Cyanine5 carboxylic acid bromide (HY-D1319) labeled Paclitaxel (HY-B0015) conjugate. Cyanine5 carboxylic acid bromide is a fluorescent dye containing a non-activated carboxylic acid (Ex=646 nm, Em=662 nm) that can be used for molecular labeling and microscopy imaging. Paclitaxel stabilizes tubulin polymerization. Paclitaxel can cause both mitotic arrest and apoptotic cell death. Paclitaxel also induces autophagy .

HY-D3448

8-Anthracene-BODIPY 505/515-di(iodine)	Fluorescent Dyes
8-Anthracene-BODIPY 505/515-di iodine (BDP-1) is an iodine-substituted BODIPY derivative and monomer for synthesis of conjugated porous polymer CPP-1. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high (Ex/Em = 505/515 nm) .

HY-D3310

Fluorescein-12-dGTP

Fluorescent Dyes

Fluorescein-12-dGTP is a fluorescein-labeled deoxyguanosine triphosphate. Fluorescein-12-dGTP incorporates into complementary allele-specific primers at SNP sites, enabling FRET with cationic conjugated polymer PFP via DNA-PFP electrostatic interactions. Fluorescein-12-dGTP incorporates into G-allele-specific primers for homozygous G/G SNP genotypes to enable genotype discrimination. Fluorescein-12-dGTP serves as a fluorescently labeled nucleotide for homogeneous solution-based SNP and FRET genotyping assays (Ex/Em = 498/517 nm) .

HY-W075731

(Ir[dF(F)ppy]2(dCF3))PF6	Fluorescent Dyes
(Ir[dF (F) ppy]₂ (dCF₃)) PF₆ is a cyclometalated iridium (III) complex that is used in visible light-mediated photocatalytic organic transformations .

Cat. No.	Product Name	Type

HY-Y0873

PEG300 Maximum Cited Publications 178 Publications Verification Polyethylene glycol 300	Biochemical Assay Reagents
PEG300 (Polyethylene glycol 300), a neutral polymer of molecular weight 300, is a water-soluble, low immunogenic and biocompatible polymer formed by repeating units of ethylene glycol .

HY-Y0873C

PEG3350 Polyethylene glycol 3350	Biochemical Assay Reagents
PEG3350 (Polyethylene glycol 3350) a neutral polymer of molecular weight 3350. PEG3350 used as an excellent solvent for a large number of substances.

HY-D1005A22

Poloxamer 338 (F108) PEG-PPG-PEG, 14600 (Average)	Biochemical Assay Reagents
Poloxamer 338 F108 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 14600. Poloxamer 338 F108 reduces the aggregation of red blood cells, inhibits proliferation of human lymphocyte cell IIBR1. Poloxamer 338 F108 exhibits short-term and subchronic toxicity in rats .

HY-D1005A6

Poloxamer 124 (L44)

PEG-PPG-PEG, 2200 (Average)

Biochemical Assay Reagents

Poloxamer 124 L44 is a block polymer of polyoxyethylene and polyoxypropylene and a hydrophobic surfactant. Poloxamer 124 L44 causes eye irritation and exhibits oral toxicity in albino rats with an LD₅₀ of 5 g/kg. Poloxamer 124 L44 has reversible adverse effects on triglyceride and cholesterol transport in the lymphatic system of rats. Poloxamer 124 L44 can form thermoreversible hydrogels and is used as a food additive and as a drug delivery vehicle in cosmetics, pharmaceuticals, and tissue engineering[1][2][3].

HY-Y0873M

PEG500 Polyethylene glycol 500	Biochemical Assay Reagents
PEG500 (Polyethylene glycol 500) is a versatile polymer that's used as a solvent, dispersant, lubricant, and more in industries like pharmaceuticals and biotechnology, and it can also modify liposomes. PEG500 is commonly used as a solvent or carrier for drugs, helping with capsule endoscopy to improve image quality and cecum completion rates .

HY-B1620B

Polyvinylpyrrolidone K15 PVP K15; Polyvidone K15; Povidone K15	Biochemical Assay Reagents
Polyvinylpyrrolidone K15 is a linear non-ionic polymer devises vigorous bright crystalline layers and has adhesive, cohesive and dispersive properties .

HY-W007432

RuPhos	Biochemical Assay Reagents
RuPhos is a Buchwald ligand. In aqueous Suzuki-Miyaura catalytic transfer polymerization, RuPhos forms inactive Pd (RuPhos)₂ with palladium and inhibits diffusion to improve polymerization controllability. RuPhos additional addition in anhydrous Kumada polymerization exacerbates catalyst deactivation and chain transfer, significantly impairing polymerization control .

HY-D1005A2

Poloxamer 105 (L35) PEG-PPG-PEG, 1900 (Average)	Biochemical Assay Reagents
Poloxamer 105 L35 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 1900 Da. Poloxamer 105 L35 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-W017894

TPO-L	Biochemical Assay Reagents
TPO-L is a photoinitiator for the 3D printing of resin that promotes two-photon induced polymerization. The two-photon absorption cross-section spectrum of Lucirin TPO-L shows a maximum of 1.2 GM at 610 nm. Despite its small two-photon absorption cross-section, Lucirin TPO-L exhibits high polymerization quantum yields .

HY-D1005A8

Poloxamer 181 (L61)

PEG-PPG-PEG, 2000 (Average)

Biochemical Assay Reagents

Poloxamer 181 L61 is a block polymer of polyethylene oxide and polypropylene oxide with an average molecular weight of 2000. Poloxamer has the ability to inhibit P-gp. Poloxamer 181 has antimicrobial activity and can inhibit Mycobacterium avium. Poloxamer 181 can form a thermally reversible hydrogel and is used as a food additive, and as an agent delivery carrier in cosmetics, pharmaceuticals and tissue engineering .

HY-Y1134

D-Tartaric acid

D-(-)-Tartaric acid

Biochemical Assay Reagents

D-Tartaric acid (D-(-)-Tartaric acid) serves as an additive in beverages and other food products. When combined with pyrrole, D-Tartaric acid is used to construct a D-TA/polypyrrole-based bacterial imprinted polymer sensor for the detection of Vibrio parahaemolyticus. D-Tartaric acid enhances the sensitivity of polypyrrole-based bacterial imprinted polymer sensors for detecting Vibrio parahaemolyticus. D-Tartaric acid is applicable to research on Vibrio parahaemolyticus infection .

HY-Y0850U4

PVA (Mw 145000, 99+% hydrolyzed, ~3300 polymerization) 1 Publications Verification Polyvinyl alcohol (Mw 145000, 99+% hydrolyzed, ~3300 polymerization); Poly(Ethenol) (Mw 145000, 99+% hydrolyzed, ~3300 polymerization)	Biochemical Assay Reagents
PVA (Mw 145000, 99+% hydrolyzed, ~3300 polymerization) is a polyvinyl alcohol with molecular weight of 145000 with hydrolysis properties. PVA (Mw 145000, 99+% hydrolyzed, ~3300 polymerization) is obtained by polymerizing vinyl acetate followed by hydrolysis to remove acetate groups, yielding polyvinyl alcohol .

HY-W089777

3-Glycidyloxypropyltrimethoxysilane GPTMS	Biochemical Assay Reagents
3-Glycidyloxypropyltrimethoxysilane (GPTMS) is a silicon source for the preparation of inorganic-organic hybrid polymers. 3-Glycidyloxypropyltrimethoxysilane can be used to prepare hard coatings of organic polymers, such as contact lens materials in the optical industry, as well as related materials in the fields of electronics, thin films, sensors, nanoimprinting, waveguides, and biology .

HY-W105423

Methacrylic acid N-hydroxysuccinimide ester NHS-MA	Biochemical Assay Reagents
Methacrylic acid N-hydroxysuccinimide ester (NHS-MA) is a polymer that serves as a monomer to prepare degradable amphiphilic block copolymer microparticles via RAFT polymerization for low pH-triggered drug delivery. Methacrylic acid N-hydroxysuccinimide ester is used for the synthesis of nanogels .

HY-131960A

Polysucrose 70	Biochemical Assay Reagents
Polysucrose 70 is a branched polysaccharide polymer with a high molecular weight. Polysucrose 70 is formed by the copolymerization of sucrose and epichlorohydrin, which can be used for cell separation .

HY-A0104B

HPMC (Type I,Viscosity:100mPa.s) Hypromellose (Type I,Viscosity:100mPa.s); (Hydroxypropyl)methyl cellulose (Type I,Viscosity:100mPa.s); Celacol HPM 5000 (Type I,Viscosity:100mPa.s)	Biochemical Assay Reagents
HPMC (Type I, Viscosity: 100 mPa·s) is a nonionic polymer obtained via synthetic modification of cellulose. As a hydrophilic matrix material, HPMC prolongs drug release through non-Fickian diffusion, including the diffusion of drugs within the hydrated matrix and the polymer relaxation process .

HY-139201D

Poly-D-lysine hydrobromide (MW 4000-15000) PDLHB (MW 4000-15000)	Biochemical Assay Reagents
Poly-D-lysine hydrobromide (MW 4000-15000) (PDLHB (MW 4000-15000)) is an artificially synthesized polymer matrix widely used in neuronal cell culture. Poly-D-lysine hydrobromide is also known as a calcium-sensing receptor (CaSR) agonist peptide .

HY-B1620O

Polyvinylpyrrolidone, average Mw~1300000 PVP, average Mw~1300000; Polyvidone, average Mw~1300000; Povidone, average Mw~1300000	Biochemical Assay Reagents
Polyvinylpyrrolidone, average Mw~1300000 is a multifunctional synthetic polymer with an average molecular weight of 1300000 Da. Polyvinylpyrrolidone, average Mw~1300000 shows the higher viscosity to form the fine polymer network as the molecular sieve .

HY-W007729

Boc-L-Alaninol	Biochemical Assay Reagents
Boc-L-Alaninol is a Boc-protected chiral amino alcohol. Boc-L-Alaninol can be used in the synthesis of optically active bipyridine-containing polymers .

HY-W015553

2-Vinylnaphthalene 2-Ethenylnaphthalene; 2-Vinylnaphthalene	Biochemical Assay Reagents
2-Vinylnaphthalene (2-Ethenylnaphthalene; 2-Vinylnaphthalene) is an organic polymer. 2-Vinylnaphthalene is a kind of biological materials or organic compounds that are widely used in life science research .

HY-Y0850U2

PVA (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization)

Polyvinyl alcohol (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization); Poly(Ethenol) (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization)

Biochemical Assay Reagents

PVA (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization) (Polyvinyl alcohol (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization); Poly(Ethenol) (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization)) is a biodegradable of polymer. PVA (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization) can be used to blend with various biopolymers and hydrophilic synthetic polymers to improve mechanical properties of films .

HY-Y0850U1

PVA (Mw 61000, 98-99% hydrolyzed, ~1400 polymerization) Polyvinyl alcohol (Mw 61000, 98-99% hydrolyzed, ~1400 polymerization); Poly(Ethenol) (Mw 61000, 98-99% hydrolyzed, ~1400 polymerization)	Biochemical Assay Reagents
PVA (Mw 61000, 98-99% hydrolyzed, ~1400 polymerization) (Polyvinyl alcohol (Mw 61000, 98-99% hydrolyzed, ~1400 polymerization); Poly(Ethenol) (Mw 61000, 98-99% hydrolyzed, ~1400 polymerization)) is a biodegradable of polymer. PVA (Mw 61000, 98-99% hydrolyzed, ~1400 polymerization) can be used to produce bio-composite films .

HY-Y0850U7

PVA (Mw 195000, 98-99% hydrolyzed, ~4300 polymerization) Polyvinyl alcohol (Mw 195000, 98-99% hydrolyzed, ~4300 polymerization); Poly(Ethenol) (Mw 195000, 98-99% hydrolyzed, ~4300 polymerization)	Biochemical Assay Reagents
PVA (Mw 195000, 98-99% hydrolyzed, ~4300 polymerization) is polyvinyl alcohol with a molecular weight of 195,000 and hydrolytic properties. PVA (Mw 195000, 98-99% hydrolyzed, ~4300 polymerization) is obtained by polymerizing vinyl acetate followed by hydrolysis to remove acetate groups, yielding polyvinyl alcohol .

HY-Y0850U

PVA (Mw 31000, 87-89% hydrolyzed, ~630 polymerization) Polyvinyl alcohol (Mw 31000, 87-89% hydrolyzed, ~630 polymerization); Poly(Ethenol) (Mw 31000, 87-89% hydrolyzed, ~630 polymerization)	Biochemical Assay Reagents
PVA (Mw 31000, 87-89% hydrolyzed, ~630 polymerization) (Polyvinyl alcohol (Mw 31000, 87-89% hydrolyzed, ~630 polymerization); Poly(Ethenol) (Mw 31000, 87-89% hydrolyzed, ~630 polymerization)) is a biocompatible, biodegradable, nontoxic and hydrophilic synthetic polymer. PVA (Mw 31000, 87-89% hydrolyzed, ~630 polymerization) can be used to produce bone tissue engineering scaffold ^[1]

HY-Y0850U8

PVA (Mw 47000, 98-99% hydrolyzed, ~1000 polymerization)

Polyvinyl alcohol (Mw 47000, 98-99% hydrolyzed, ~1000 polymerization); Poly(Ethenol) (Mw 47000, 98-99% hydrolyzed, ~1000 polymerization)

Biochemical Assay Reagents

PVA (Mw 47000, 98-99% hydrolyzed, ~1000 polymerization) is a polyvinyl alcohol with molecular weight of 47000 with hydrolysis properties. Hydrolysis degree refers to the conversion rate of acetic acid group hydrolysis to hydroxyl group in the original polyvinyl acetate, PVA (Mw 47000, 98-99% hydrolyzed, ~1000 polymerization). In addition, polyvinyl alcohol is obtained from polymerization of vinyl acetate to remove acetic acid group by hydrolysis. Polyvinyl alcohol with different degrees of hydrolysis can be self-crosslinked to form frozen gels and used as biological excipients .

HY-D1005A7

Poloxamer 125 (L45) PEG-PPG-PEG, 2400 (Average)	Biochemical Assay Reagents
Poloxamer 125 L45 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 2400. Poloxamer 125 L45 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-D1005A4

Poloxamer 122 (L42)

PEG-PPG-PEG, 1630 (Average)

Biochemical Assay Reagents

Poloxamer 122 L42 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 1630. Poloxamer 122 L42 exhibits antimicrobial activity, that inihibits 56% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 122 L42 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .

HY-145941

AETA 2-Acryloxyethyltrimethylammonium chloride	Biochemical Assay Reagents
AETA (2-Acryloxyethyltrimethylammonium chloride) can be used for the synthesis of hydrophilic polymers and hydrogels. Hydrogels are used for membranes, catheters, contact lenses, and drug delivery systems .

HY-167006

PLGA10000-PEG3000-VS PLGA10000-PEG3000-Vinylsulfone	Biochemical Assay Reagents
PLGA10000-PEG3000-VS (PLGA10000-PEG3000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .

HY-167055

PLLA4000-PEG2000-VS PLLA4000-PEG2000-Vinylsulfone	Biochemical Assay Reagents
PLLA4000-PEG2000-VS (PLLA4000-PEG2000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .

HY-167033

PLGA4000-PEG5000-VS PLGA4000-PEG5000-Vinylsulfone	Biochemical Assay Reagents
PLGA4000-PEG5000-VS (PLGA4000-PEG5000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .

HY-167047

PLLA5000-PEG1000-VS PLLA5000-PEG1000-Vinylsulfone	Biochemical Assay Reagents
PLLA5000-PEG1000-VS (PLLA5000-PEG1000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .

HY-167035

PLGA5000-PEG2000-VS PLGA5000-PEG2000-Vinylsulfone	Biochemical Assay Reagents
PLGA5000-PEG2000-VS (PLGA5000-PEG2000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .

HY-W090151

Silyl-ether based ROMP monomer iPrSi	Biochemical Assay Reagents
Silyl-ether based ROMP monomer iPrSi is a biochemical reagent that can be used in the synthesis of advanced polymer materials for biomedical applications, including drug delivery vehicles and hydrogels .

HY-163977

Silyl-ether based ROMP Monomer 2,2-Diphenyl-1,3-dioxa-2-silacyclooct-5-ene	Biochemical Assay Reagents
Silyl-ether based ROMP Monomer (2,2-Diphenyl-1,3-dioxa-2-silacyclooct-5-ene) is a biochemical reagent that can be used in the synthesis of advanced polymer materials for biomedical applications, including drug delivery vehicles and hydrogels .

HY-167357

PLLA3000-PEG1000-PLLA3000	Biochemical Assay Reagents
PLLA3000-PEG1000-PLLA3000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA3000-PEG1000-PLLA3000 can be used in drug delivery research .

HY-167118

PLLA5000-PEG6000-PLLA5000	Biochemical Assay Reagents
PLLA5000-PEG6000-PLLA5000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA5000-PEG6000-PLLA5000 can be used in drug delivery research .

HY-167352

PLLA3000-PEG8000-PLLA3000	Biochemical Assay Reagents
PLLA3000-PEG8000-PLLA3000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA3000-PEG8000-PLLA3000 can be used in drug delivery research .

HY-167019

PLGA2000-PEG5000-VS PLGA2000-PEG5000-Vinylsulfone	Biochemical Assay Reagents
PLGA2000-PEG5000-VS (PLGA2000-PEG5000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .

HY-167027

PLGA3000-PEG5000-VS PLGA3000-PEG5000-Vinylsulfone	Biochemical Assay Reagents
PLGA3000-PEG5000-VS (PLGA3000-PEG5000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .

HY-167051

PLLA1000-PEG5000-VS PLLA1000-PEG5000-Vinylsulfone	Biochemical Assay Reagents
PLLA1000-PEG5000-VS (PLLA1000-PEG5000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .

HY-167030

PLGA4000-PEG2000-VS PLGA4000-PEG2000-Vinylsulfone	Biochemical Assay Reagents
PLGA4000-PEG2000-VS (PLGA4000-PEG2000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .

HY-167032

PLGA4000-PEG3000-VS PLGA4000-PEG3000-Vinylsulfone	Biochemical Assay Reagents
PLGA4000-PEG3000-VS (PLGA4000-PEG3000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .

HY-167062

PLLA2000-PEG3000-VS PLLA2000-PEG3000-Vinylsulfone	Biochemical Assay Reagents
PLLA2000-PEG3000-VS (PLLA2000-PEG3000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .

HY-167005

PLGA10000-PEG2000-VS PLGA10000-PEG2000-Vinylsulfone	Biochemical Assay Reagents
PLGA10000-PEG2000-VS (PLGA10000-PEG2000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .

HY-167052

PLLA2000-PEG1000-VS PLLA2000-PEG1000-Vinylsulfone	Biochemical Assay Reagents
PLLA2000-PEG1000-VS (PLLA2000-PEG1000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .

HY-167038

PLGA5000-PEG5000-VS PLGA5000-PEG5000-Vinylsulfone	Biochemical Assay Reagents
PLGA5000-PEG5000-VS (PLGA5000-PEG5000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .

HY-167018

PLGA2000-PEG3000-VS PLGA2000-PEG3000-Vinylsulfone	Biochemical Assay Reagents
PLGA2000-PEG3000-VS (PLGA2000-PEG3000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .

HY-167013

PLGA1000-PEG5000-VS PLGA1000-PEG5000-Vinylsulfone	Biochemical Assay Reagents
PLGA1000-PEG5000-VS (PLGA1000-PEG5000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .

HY-167054

PLLA2000-PEG2000-VS PLLA2000-PEG2000-Vinylsulfone	Biochemical Assay Reagents
PLLA2000-PEG2000-VS (PLLA2000-PEG2000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .

Cat. No.	Product Name	Target	Research Area

HY-P0027

Jasplakinolide Maximum Cited Publications 9 Publications Verification	Arp2/3 Complex Fungal	Infection Cancer
Jasplakinolide is a potent actin polymerization inducer and stabilizes pre-existing actin filaments. Jasplakinolide binds to F-actin competitively with phalloidin with a K_d of 15 nM. Jasplakinolide, a naturally occurring cyclic peptide from the marine sponge, has both fungicidal and anti-cancer activity .

HY-126437B

Poly-L-lysine hydrobromide (MW 70000-150000) 1 Publications Verification	Biochemical Assay Reagents	Others
Poly-L-lysine (hydrobromide) (MW 70000-150000), a positively charged amino acid polymer, is a nonspecific attachment factor for cells. Poly-L-lysine (hydrobromide) (MW 70000-150000) has good biocompatibility. Poly-L-lysine (hydrobromide) (MW 70000-150000) is used to increase cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface .

HY-P0074

GPRP 3 Publications Verification Gly-Pro-Arg-Pro; Pefa 6003	Thrombin	Cardiovascular Disease
GPRP (Gly-Pro-Arg-Pro; Pefa 6003) is a fibrin polymerization inhibitor that inhibits the interaction between fibrinogen and the platelet membrane glycoprotein Ⅱb/IIIa complex (glycoprotein IIb/IIIa receptor) . GPRP increases the level of free thrombin in activated platelet-rich plasma by reducing the adsorption of thrombin onto fibrin. GPRP inhibits platelet aggregation and prolongs the thrombin-initiated clotting time in plasma. GPRP is applicable for research related to thrombosis and thrombotic diseases .

HY-126437D

Poly-L-lysine hydrobromide (MW ＞300000)	Biochemical Assay Reagents	Others
Poly-L-lysine hydrobromide (MW 150000-300000), a positively charged amino acid polymer, is a nonspecific attachment factor for cells. Poly-L-lysine hydrobromide (MW 150000-300000) has good biocompatibility. Poly-L-lysine hydrobromide (MW 150000-300000) is used to increase cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface .

HY-15580

Dolastatin 10 DLS 10; NSC 376128	Microtubule/Tubulin ADC Payload	Cancer
Dolastatin 10 (DLS 10) is a potent antimitotic peptide that inhibits tubulin polymerization.

HY-P10069

Ac-pSar12-OH	Drug Intermediate ADC Linker	Others
Ac-pSar12-OH is a water-soluble polymer of the polysarcosine class and can be used as a linker. Ac-pSar12-OH is a linear polypeptide derivative composed of 12 arginine units. Ac-pSar12-OH N-terminus is modified with an acetyl group, while the C-terminus retains a free hydroxyl group, which can help enhance the stability of the polypeptide .

HY-116073

L-Penicillamine	Acyltransferase	Infection Cancer
L-Penicillamine is an orally active serine palmitoyltransferase (SPT) inhibitor. L-Penicillamine inactivates the PLP cofactor by forming adducts, thereby inhibiting SPT activity and reducing sphingolipid biosynthesis. L-Penicillamine not only blocks tumor access to vitamin B6, but also stabilizes the human papillomavirus 16 E6 oncoprotein monomer and inhibits its polymerization, exhibiting a unique anticancer mechanism. L-Penicillamine effectively delays the growth of Sarcoma-180, induces tumor necrosis and prolongs survival (though long-term use may lead to Pyridoxine (HY-B1328) deficiency and weight loss) .

HY-P0074A

GPRP acetate 3 Publications Verification Gly-Pro-Arg-Pro acetate; Pefa 6003 acetate	Integrin	Cardiovascular Disease
GPRP acetate (Gly-Pro-Arg-Pro acetate) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa) .

HY-160429

PSAR18-COOH Ac-PSAR18-COOH	Drug Derivative	Others
PSAR18-COOH is a derivative of PSAR extracted from patent WO2009064913A1. PSAR is a highly hydrophilic, biodegradable, non-immunogenic and water-soluble polymer that has been employed in several delivery systems for drugs or diagnostics.

HY-P4116

pH-Low Insertion Peptide pHLIP	Peptides	Metabolic Disease Cancer
pH-Low Insertion Peptide (pHLIP) is a short, pH-responsive peptide capable of inserting across a cell membrane to form a transmembrane helix at acidic pH. pH-Low Insertion Peptide targets the acidic tumor microenvironment for tumors at early and metastatic stages with high specificity, used as a specific ligand. pH-Low Insertion Peptide successfully modify polylysine polymers to have the pH-responsive capability. pH-Low Insertion Peptide-based targeting of cancer presents an opportunity to monitor metabolic changes, and to selectively deliver imaging and therapeutic agents to tumors .

HY-P11308

Cys-GE11	EGFR	Cancer
Cys-GE11 is an N-terminal modified GE11 (HY-P10128) with cysteine (Cys) added. Cys-GE11 can be coupled through the thiol group of Cys. Cys-GE11 can be linked to PEG-P (TMC-DTC) through the N-terminus of cysteine to form a targeted polymer. Cys-GE11 can target cells with high EGFR expression (such as SMMC-7721 cells). Cys-GE11 can significantly enhance drug enrichment at the tumor site and exhibit low toxicity .

HY-P11328

GFOGER peptide	Integrin	Others
GFOGER peptide is an artificially synthesized collagen-mimetic sequence. GFOGER peptide acts as a ligand for α2β1, α11β1 and α1β1 integrins, thereby supporting integrin-mediated cell adhesion to collagen. GFOGER peptide triggers signaling pathways mediated by the α2β1 integrin receptor and upregulates osteoblast differentiation. GFOGER peptide accelerates and enhances bone formation at sites of refractory femoral defects. GFOGER peptide can be passively adsorbed onto polymer scaffolds for cell-free/growth factor-free bone formation. GFOGER peptide is used in biomaterials such as hydrogels and 3D bioinks for tissue engineering research including bone formation .

HY-P11339

c-RGD-SH	Integrin	Cancer
c-RGD-SH is a ligand for integrin αvβ3 (Integrin αvβ3). Conjugation of c-RGD-SH with core-crosslinked polymeric micelles (CCPM) enables the synthesis of a bimodal nanoprobe, which can be labeled with Cy7 and 111In for SPECT and NIRF imaging of tumors .

HY-P11009

SA-21	Peptides	Others
SA-21 is a 21-amino acid polymer peptide (Ac-RLIEDICLPRWGCLWEDD-NH2) that binds to ligands of urokinase-type plasminogen activator, Fab antibody fragments, and small proteins. SA-21 can be used to purify albumin (K_i=1.9 μM) .

HY-P4116A

pH-Low Insertion Peptide TFA pHLIP TFA	Peptides	Metabolic Disease Cancer
pH-Low Insertion Peptide TFA (pHLIP TFA) is a short, pH-responsive peptide capable of inserting across a cell membrane to form a transmembrane helix at acidic pH. pH-Low Insertion Peptide TFA targets the acidic tumor microenvironment for tumors at early and metastatic stages with high specificity, used as a specific ligand. pH-Low Insertion Peptide TFA successfully modifys polylysine polymers to have the pH-responsive capability. pH-Low Insertion Peptide TFA -based targeting of cancer presents an opportunity to monitor metabolic changes and to selectively deliver imaging and therapeutic agents to tumors .

HY-P11339A

c-RGD-SH TFA	Integrin	Cancer
c-RGD-SH TFA is an Integrin αvβ3 ligand. c-RGD-SH TFA conjugated with core-crosslinked polymeric micelles (CCPM) can be used for synthesis a dual modality nanoparticle probe, and this probe labeled with both Cy7 and ¹¹¹In can be used for SPECT and NIRF imaging of tumor .

HY-P4822

Acetyl-PHF5 amide	Tau Protein	Others
Acetyl-PHF5 amide is an amyloidogenic protein tau peptide. Acetyl-PHF5 amide can polymerization into filamentous structures .

HY-P10993

CT20p	Bcl-2 Family	Cancer
CT20p is an anticancer peptide based on the C hydrophobic terminus of Bax. CT20p has a unique cytotoxic effect independent of full-length Bax, and can act on mitochondria, leading to fusion-like aggregation and mitochondrial membrane hyperpolarization. CT20p can reduce α5β1 integrin levels and inhibit F-actin polymerization, thereby destroying the cytoskeleton and preventing cell attachment. CT20p can be used in the study of breast cancer .

HY-159703

Glu-Cys Glutamyl-cysteine; PSSGlu-Cys	Endogenous Metabolite	Others
Glu-Cys (Glutamyl-cysteine; PSSGlu-Cys) is a dipeptide composed of L-glutamic acid (HY-14608) and L-cysteine (HY-Y0337) joined by a peptide linkage .

HY-P2708

H-Gly-Pro-Arg-Pro-NH2	Integrin	Cardiovascular Disease
H-Gly-Pro-Arg-Pro-NH2 is a peptide that mimics the N-terminal Gly-Pro-Arg region in the a chain of fibrin protein. H-Gly-Pro-Arg-Pro-NH2 prevents fibrin polymerization .

HY-P10293

NQEQVSP	Thrombin Peptides	Others
NQEQVSP, a fibrin-binding protein-derived peptide (FBP), is a factor XIIIa substrate. NQEQVSP can be recognized by factor XIII and is enzymatically conjugated into fibrin during polymerization .

HY-P3531

Fibrinogen γ-chain (397-411)	Peptides	Others
Fibrinogen γ-chain (397-411), a esidues 397-411 of the γ chain of fibrinogen, is a site recognizing the platelet receptor, which is distinct from the site(s) involved in polymerization of fibrin monomers .

HY-P3894

P34cdc2 Kinase Fragment	Microtubule/Tubulin Mitosis	Others
P34cdc2 Kinase Fragment is associated with the completion of DNA replication in yeast mitosis. P34cdc2 Kinase can phosphorylate mitogen-activated protein 2 (MAP2) to regulate microtubules polymerization in Xenopus oocytes meiosis .

HY-P10589

Phomopsinamine A	Microtubule/Tubulin	Cancer
Phomopsinamine A is a derivative of Phomopsin A (HY-N6793). Phomopsinamine A is an inhibitor for tubulin polymerization with IC₅₀ of 0.53 μM. Phomopsinamine A inhibits the binding of Vinblastine (HY-13780) to tubulin (IC₅₀ =0.56 μM), promotes the the binding of Colchicine (HY-16569) to tubulin (IC₅₀ =0.32 μM) .

HY-P11140

KSL-W	Bacterial Reactive Oxygen Species (ROS)	Infection Inflammation/Immunology
KSL-W is a multifunctional antibacterial peptide with immune regulatory function. KSL-W has a chemotactic effect on neutrophils. KSL-W can induce neutrophil F-actin polymerization dependent on the Gαi protein signaling pathway. KSL-W can inhibit the production of reactive oxygen species (ROS) in neutrophils. KSL-W can be used for research on infection control and inflammation regulation .

HY-P11770

α-Tubulin (residues 440–451)	Microtubule/Tubulin	Others
α-Tubulin (residues 440-451) (α-Tubulin Tail) is a Microtubule growth inhibitor. α-Tubulin (residues 440-451) transiently interacts with the longitudinal polymerization interface of α-tubulin, regulating the apparent association and dissociation rates of tubulin at the microtubule growing end. α-Tubulin (residues 440-451) inhibits microtubule growth .

HY-P10739C

WYRGRLC	Collagen Apoptosis	Inflammation/Immunology
WYRGRLC is a type II collagen-targeting peptide. WYRGRLC specifically binds to type II collagen α1 in articular cartilage in a sequence-dependent manner. WYRGRLC inhibits the binding of WYRGRL-displaying phage (C1-3) to articular cartilage in a sequence-specific manner. WYRGRLC can act as a retention enhancer to improve the cartilage-targeting ability of polymeric nanoparticles and liposomal nanoplatforms, facilitating the delivery of Rapamycin (HY-10219) to chondrocytes. WYRGRLC can be used in studies related to osteoarthritis .

Cat. No.	Product Name

HY-K2029

HP PolyFast Transfection Reagent
MCE HP PolyFast Transfection Reagent is a novel cationic polymer transfection reagent for DNA and RNA transfection.

HY-K2031

Lentivirus Concentration Solution (5×)
MCE Lentivirus Concentration Solution (5×) is a high-efficiency polymer solution optimized for lentiviral particle enrichment, providing a simple, rapid, and effective method for lentivirus concentration.

HY-K1014

PolyFast Transfection Reagent Maximum Cited Publications 40 Publications Verification
MCE PolyFast Transfection Reagent consists of cationic polymers and can introduce nucleic acids (DNA or RNA) into eukaryotic cells efficiently, including some hard-to-transfect cells.

HY-K2017

siRNA/miRNA Transfection Reagent 5+ Cited Publications
MCE siRNA/miRNA Transfection Reagent is a novel cationic polymer transfection reagent for siRNA and miRNA transfection. The 1 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

HY-K2015

Lentivirus Transfection Reagent 1 Publications Verification
MCE Lentivirus Transfection Reagent is a new type of transfection reagent based on cationic polymer, which is suitable for lentivirus packaging and transfection. It significantly improves the efficiency of packaging and transfection, resulting in the production of more recombinant lentivirus.

Cat. No.	Product Name	Target	Research Area	Image

HY-P9980

Belantamab 2 Publications Verification GSK2857914	ADC Antibody TNF Receptor	Cancer
Belantamab (GSK2857916) is a humanized IgG1 anti-BCMA/TNFRSF17 monoclonal antibody. Belantamab is linked to MMAF (HY-15579) through a non-cleavable ADC linker to synthesize the antibody-active molecule conjugate (ADC) Belantamab mafodotin (HY-P3239). After binding to BCMA on the surface of tumor cells, Belantamab mafodotin enters the cell through receptor-mediated endocytosis. After entering the cell, Belantamab mafodotin releases MMAF, blocks cell division by inhibiting tubulin polymerization, arrests the cell cycle and induces cell apoptosis. Belantamab can be used for the study of multiple myeloma, especially relapsed/refractory multiple myeloma .

HY-164153

ADC Control Human IgG1-vcMMAE (solution)	Antibody-Drug Conjugates (ADCs) Microtubule/Tubulin	Cancer
ADC Control Human IgG1-vcMMAE (solution) is a humanized monoclonal antibody that is an isotype control of ADC human IgG1-vcMMAE and can inhibit tubulin polymerization. The antibody portion is Human IgG1 kappa, Isotype Control (HY-P99001), and the drug-linker conjugate for ADC is vcMMAE (HY-15575) .

HY-P99682

Ladiratuzumab hLIV22	ADC Antibody	Cancer
Ladiratuzumab (hLIV22) is a humanized monoclonal antibody against zinc transporter LIV-1/ZIP6. Ladiratuzumab is conjugated to MMAE (HY-15162) via a cleavable dipeptide linker to synthesize an antibody-drug conjugate (ADC) Ladiratuzumab vedotin (HY-P99683). Ladiratuzumab vedotin selectively targets LIV-1 protein overexpressed on the surface of tumor cells, enters cells through antibody-mediated receptor endocytosis, releases MMAE to inhibit microtubule polymerization, and kills adjacent tumor cells with a bystander effect. Ladiratuzumab can be used in the study of solid tumors such as metastatic triple-negative breast cancer (mTNBC) .

HY-P991372

Anti-TROP2 Antibody RN927C antibody	TROP2	Cancer
Anti-TROP2 Antibody (RN927C antibody) is a human monoclonal antibody targeting Trop-2. Anti-TROP2 Antibody exerts in vitro inhibitory effects on a variety of tumor cell lines. Anti-TROP2 Antibody exhibits anti-tumor activity in mouse pancreatic PDX, ovarian PDX, lung PDX and triple-negative breast cancer (TNB) PDX models. Anti-TROP2 Antibody can be used for research on pancreatic cancer, ovarian cancer, lung cancer and triple-negative breast cancer .

HY-164154

ADC Control Human IgG1-vcMMAF	Antibody-Drug Conjugates (ADCs) Microtubule/Tubulin	Cancer
ADC Control Human IgG1-vcMMAF is a humanized monoclonal antibody that is an isotype control of ADC human IgG1-vcMMAF and can inhibit tubulin polymerization. The antibody portion is Human IgG1 kappa, Isotype Control (HY-P99001), and the drug-linker conjugate for ADC is MC-Val-Cit-PAB-MMAF (vcMMAF; HY-112786) .

HY-P992439

PF-06747143	CXCR	Cancer
PF-06747143 is recombinant anti-human antibody targeting CXCR4. PF-06747143 blocks CXCL12-induced calcium flux, F-actin polymerization, chemotaxis, cell migration, and leukemic cell bone marrow homing. PF-06747143 reduces tumor burden and improves survival in mouse models of hematologic malignancies. PF-06747143 can be used for the research of chronic lymphocytic leukemia, acute myeloid leukemia, and hematologic malignancies .

HY-P992382

IC 100	Interleukin Related	Neurological Disease Inflammation/Immunology
IC 100 is a humanized IgG4κ monoclonal antibody targeting apoptosis-associated speck-like protein (ASC) with blood-brain barrier permeability. IC 100 specifically inhibits ASC after being endocytosed via its Fc segment, blocks ASC polymerization and inflammasome activation, suppresses IL-1β release, forms complexes with ASC and TRIM21, and evades TRIM21-mediated proteasomal degradation. IC 100 alleviates symptoms associated with autoimmune encephalomyelitis, reduces immune cell infiltration and microglial activation in the mouse EAE model. IC 100 is suitable for research on neuroinflammatory and inflammasome-related diseases such as multiple sclerosis. Isotype comparison: HY-P99003 .

Species:	Human (2) Mouse (1)
Tag:	His (2) Strep (1)
Source:	HEK293 (3)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P74631

	PIGR Protein, Mouse (HEK293, His) polymeric Immunoglobulin Receptor; Poly-Ig Receptor; PIGR	Mouse	HEK293
	PIGR proteins mediate the selective transcytosis of polymerized IgA and IgM across mucosal epithelial cells.It binds to these immunoglobulins at the basolateral surface, forming complexes that are transported intracellularly and secreted at the apical surface.PIGR Protein, Mouse (HEK293, His) is the recombinant mouse-derived PIGR protein, expressed by HEK293 , with C-His labeled tag.

HY-P704846

	PIGR Protein, Human (HEK293, Twin-Strep) polymeric Immunoglobulin Receptor; PIgR; Poly-Ig Receptor; Hepatocellular Carcinoma-Associated Protein TB6; PIGR	Human	HEK293

HY-P71065

	PIGR Protein, Human (G365S, HEK293, His) polymeric Immunoglobulin Receptor; PIgR; Poly-Ig Receptor; Hepatocellular Carcinoma-Associated Protein TB6; PIGR	Human	HEK293
	PIGR proteins play a critical role in mediating the selective transcytosis of polymerized IgA and IgM across mucosal epithelial cells, which is critical for mucosal immunity. PIGR binds these immunoglobulins at the basolateral surface, forming a complex that is transported intracellularly and secreted apically. PIGR Protein, Human (G365S, HEK293, His) is the recombinant human-derived PIGR protein, expressed by HEK293 , with C-6*His labeled tag.

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Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
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Appearance
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Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Host:	Mouse (3)
Reactivity:	Human (3)
Application:	IHC-P (2) ELISA (3)
Isotype:	IgG1 (2)
Conjugation:	Non-conjugated (3)
Clonality:	Monoclonal (2)
Modification:	Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P87399

	Polymeric immunoglobulin receptor/PIGR Antibody (YA7087)	IHC-P, ELISA	Human
	Polymeric immunoglobulin receptor/PIGR Antibody (YA7087) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Polymeric immunoglobulin receptor/PIGR.

HY-P87399A

	Polymeric immunoglobulin receptor/PIGR Antibody (YA7087)(PBS only)	IHC-P, ELISA	Human
	Polymeric immunoglobulin receptor/PIGR Antibody (YA7087) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Polymeric immunoglobulin receptor/PIGR.

HY-P84985

	CD300e Antibody (YA4677) CMRF35-like molecule 2; CLM-2; CD300 antigen-like family member E; CMRF35-A5; Immune receptor expressed on myeloid cells 2; IREM-2; polymeric immunoglobulin receptor 2; PIgR-2; PIgR2; Poly-Ig receptor 2; CD antigen CD300e; ,CD300e nanobody;	ELISA	Human
	CD300e Antibody (YA4677) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CD300e.

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Products	In-stock - + Add to Cart
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Host
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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-136314

DBCO-PEG4-VC-PAB-MMAE		DBCO ADC Synthesis
DBCO-PEG4-VC-PAB-MMAE consists a ADC linker (DBCO-PEG4-VC-PAB) and a tubulin polymerization inhibitor MMAE (HY-15162). DBCO-PEG4-VC-PAB-MMAE can be used in the synthesis of antibody-agent conjugates (ADCs). MMAE is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. DBCO-PEG4-VC-PAB-MMAE is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-W440835

DSPE-PEG2000-DBCO DSPE-PEG2000(2000)-DBCO		DBCO
DSPE-PEG2000-DBCO is a phospholipid-PEG polymer that can be used to form micelles as lipid nanoparticles for drug delivery . DSPE-PEG2000-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-133492

DBCO-PEG4-MMAF		ADC Synthesis DBCO
DBCO-PEG4-MMAF is a agent-linker conjugate for ADC with potent antitumor activity by using the tubulin polymerization inhibitor, MMAF, linked via the linker DBCO-PEG4. DBCO-PEG4-MMAF is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-130990

DBCO-PEG4-Val-Cit-PAB-MMAF		DBCO ADC Synthesis
DBCO-PEG4-Val-Cit-PAB-MMAF consists a cleavable 4 unit PEG ADC linker (DBCO-PEG4-Val-Cit-PAB) and a potent tubulin polymerization inhibitor (MMAF). DBCO-PEG4-Val-Cit-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-Val-Cit-PAB-MMAF is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-W440835E

DSPE-PEG5000-DBCO		DBCO
DSPE-PEG5000-DBCO is a phospholipid-PEG polymer that can be used to form micelles as lipid nanoparticles for drug delivery . DSPE-PEG5000-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-W440833

DSPE-PEG3400-azide		Azide
DSPE-PEG3400-azide is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelles formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form triazole bond.

HY-W250928D

Biotin-PEG3400-azide		Azide
Biotin-PEG3400-azide is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; azide, is a moderately good leaving group, can react with alkyne by Cu-catalyzation, which improve the efficiency of biotin binding targets. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-W250928C

Biotin-PEG2000-azide		Azide
Biotin-PEG2000-azide is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; azide, is a moderately good leaving group, can react with alkyne by Cu-catalyzation, which improve the efficiency of biotin binding targets. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-W440834

DSPE-PEG5000-azide		Azide
DSPE-PEG5000-azide is a click chemistry reactive phospholipid polyPEG which forms lipid bilayer or micelles in an aqueous solution. The polymer can be used to prepare liposomes or nanoparticles used for delivering nutrients or therapeutic agents, for example mRNA or DNA vaccine.

HY-174929A

DBCO-PEG5000-Amine DBCO-PEG5000-NH2		DBCO
DBCO-PEG5000-Amine (DBCO-PEG5000-NH2) is a polyethylene glycol derivative containing dibenzocyclooctyne. DBCO-PEG-Amine is a universal, modular "bridge molecule": it forms stable covalent linkage with target materials (e.g., MSN or polymers) via the amino group at one end, while the DBCO group at the other end enables efficient, specific, and biocompatible click chemical conjugation with any azide-bearing biological entities (e.g., bacteria, cells) in subsequent steps .

HY-133190

Bis-propargyl-PEG7		Alkynes PROTAC Synthesis
Bis-propargyl-PEG7 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG7 can be used to synthesize the polymer linked multimers of guanosine-3', 5'-cyclic monophosphates . Bis-propargyl-PEG7 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-151749

N3-D-Lys(Fmoc)-OH		Azide
N3-D-Lys(Fmoc)-OH is a click chemistry reagent containing an azide group. Click chemistry is a powerful chemical reaction with excellent bioorthogonality features: biocompatible, rapid and highly specific in biological environments . N3-D-Lys(Fmoc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-151736

N3-L-Dap(Boc)-OH		Azide
N3-L-Dap(Boc)-OH is a click chemistry reagent containing an azide group. Click chemistry is a powerful chemical reaction with excellent bioorthogonality features: biocompatible, rapid and highly specific in biological environments . N3-L-Dap(Boc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-151744

N3-TFBA-O2Oc		Azide Labeling and Fluorescence Imaging
N3-TFBA-O2Oc is a click chemistry reagent containing an azide group and an aryl group. Aryl azides are well-known precursors of nitrenes and have been introduced by Fleet et al. as versatile photoaffinity labeling agents to probe biological receptors. This type of compounds has been used as photo-cross linker (λ_max=258 nm) in estrogen receptor studies and for direct surface coating of carbon and organic based polymers . N3-TFBA-O2Oc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-W440835D

DSPE-PEG3400-DBCO		DBCO
DSPE-PEG3400-DBCO is a phospholipid-PEG polymer that can be used to form micelles as lipid nanoparticles for drug delivery . DSPE-PEG3400-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-117186

Bis-propargyl-PEG6		PROTAC Synthesis Alkynes
Bis-propargyl-PEG6 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG6 can be used to synthesize the polymer linked multimers of guanosine-3', 5'-cyclic monophosphates . Bis-propargyl-PEG6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-174929

DBCO-PEG3400-Amine DBCO-PEG3400-NH2		DBCO
DBCO-PEG3400-Amine (DBCO-PEG3400-NH2) is a polyethylene glycol derivative containing dibenzocyclooctyne. DBCO-PEG-Amine is a universal, modular "bridge molecule": it forms stable covalent linkage with target materials (e.g., MSN or polymers) via the amino group at one end, while the DBCO group at the other end enables efficient, specific, and biocompatible click chemical conjugation with any azide-bearing biological entities (e.g., bacteria, cells) in subsequent steps .

HY-159921

Tubulin Polymerization-IN-1 prodrug		Alkynes
Tubulin Polymerization-IN-1 prodrug (Compound 2b) is a palladium (Pd)-mediated tubulin polymerization inhibitor prodrug. Developed based on colchicine binding site inhibitors (CBSIs), it reduces toxicity and enhances targeted release properties. Compared to the parent compound, Tubulin Polymerization-IN-1 prodrug exhibited 68.3-fold lower cytotoxicity, which can be restored in situ in the presence of Pd resin. Mechanistic studies showed that its anticancer activity is consistent with CBSIs. In vivo, Tubulin Polymerization-IN-1 prodrug significantly inhibited tumor growth (63.2%) when activated by Pd resin. It holds promise for research in the field of anticancer therapy .

HY-W440831

DSPE-PEG1000-azide		Azide
DSPE-PEG1000-azide is a phospholipid with covalently attached polydisperse PEG. This polymer is commonly used for the preparation of long circulating liposomes. The azide moiety is reactive with alkyne to form a stable triazole bond.

HY-W440835A

DSPE-PEG400-DBCO		DBCO
DSPE-PEG400-DBCO is a phospholipid-PEG polymer that can be used to form micelles as lipid nanoparticles for drug delivery . DSPE-PEG400-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-W440835B

DSPE-PEG600-DBCO		DBCO
DSPE-PEG600-DBCO is a phospholipid-PEG polymer that can be used to form micelles as lipid nanoparticles for drug delivery . DSPE-PEG600-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-W440835C

DSPE-PEG1000-DBCO		DBCO
DSPE-PEG1000-DBCO is a phospholipid-PEG polymer that can be used to form micelles as lipid nanoparticles for drug delivery . DSPE-PEG1000-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-W440835H

DSPE-PEG10000-DBCO		DBCO
DSPE-PEG10000-DBCO is a phospholipid-PEG polymer that can be used to form micelles as lipid nanoparticles for drug delivery . DSPE-PEG10000-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-147206C

Biotin-PEG3400-Alk		Alkynes
Biotin-PEG3400-Alk is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG3400-Alk is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-147206A

Biotin-PEG1000-Alk		Alkynes
Biotin-PEG1000-Alk is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG1000-Alk is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-147206E

Biotin-PEG10000-Alk		Alkynes
Biotin-PEG10000-Alk is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG10000-Alk is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-147206B

Biotin-PEG2000-Alk		Alkynes
Biotin-PEG2000-Alk is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG2000-Alk is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-147206F

Biotin-PEG20000-Alk		Alkynes
Biotin-PEG20000-Alk is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG20000-Alk is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-Y0873

PEG300 Maximum Cited Publications 178 Publications Verification Polyethylene glycol 300		Cosolvents Emulsifiers Bases
PEG300 (Polyethylene glycol 300), a neutral polymer of molecular weight 300, is a water-soluble, low immunogenic and biocompatible polymer formed by repeating units of ethylene glycol .

HY-112735

Hexadimethrine bromide 105+ Cited Publications Polybrene; 1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide		Polymers
Hexadimethrine bromide (Polybrene) is a cationic polymer used routinely to enhance the efficiency of retrovirus vector-mediated gene transfer .

HY-142979

DSPE-PEG 2000 10+ Cited Publications (C2H4O)nC42H82NO10P		Pegylated Lipids
DSPE-PEG 2000 is a PEG polymer containing DSPE and amine end groups. DSPE-PEG 2000 can be used to form micelles as nanoparticles for drug delivery .

HY-W243303A

Poly(acrylic acid) (MW 2000)		Polymers
Poly(acrylic acid) (MW 2000) is a polyacrylic acid with a molecular weight of 2000. Poly(acrylic acid) (MW 2000) is an anionic polymer. Poly(acrylic acid) (MW 2000) can be as a corrosion-mitigating and surface-stabilizing agent.

HY-W243303E

Poly(acrylic acid) (MW 450000)		Polymers
Poly(acrylic acid) (MW 450000) is a polyacrylic acid with a molecular weight of 450000. Poly(acrylic acid) (MW 450000) is an anionic polymer. Poly(acrylic acid) (MW 450000) can be as a corrosion-mitigating and surface-stabilizing agent .

HY-107799

Castor oil 5 Publications Verification		Solvents
Castor oil is a natural triglyceride and a solvent. Castor oil has a laxative effect and induces labor in pregnant females. Castor oil can be used as a solvent, co-solvent, stabilizing agent and polyol for the formation of polymer-nanoparticle composites .

HY-W440835

DSPE-PEG2000-DBCO DSPE-PEG2000(2000)-DBCO		Pegylated Lipids
DSPE-PEG2000-DBCO is a phospholipid-PEG polymer that can be used to form micelles as lipid nanoparticles for drug delivery . DSPE-PEG2000-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-Y0850H

Polyvinyl alcohol (Mw 89000-98000, 99+% hydrolyzed) 3 Publications Verification PVA (Mw 89000-98000, 99+% hydrolyzed); Poly(Ethenol) (Mw 89000-98000, 99+% hydrolyzed)		Polymers
Polyvinyl alcohol (Mw 89000-98000, 99+% hydrolyzed) also known as PVA, is a vinyl water-soluble polymer that can be used as a non-ionic surfactant. It can also be used as a biodegradable polymer and can be used in adhesives, coatings, textiles, ceramics and cosmetics .

HY-155882

mPEG750-amine mPEG750-NH2		Polymers
mPEG750-amine (mPEG750-NH2) is a chemical modification reagent for nanoparticles, capable of covalently binding to Ad-PVA to form Ad-PVA-PEG polymers. mPEG750-amine stabilizes gene delivery complexes by providing steric hindrance, reducing particle aggregation, while enhancing the water solubility and serum stability of the complex, reducing carrier cytotoxicity, and assisting in the efficient condensation of pDNA by cationic components to form nanoparticles that can be endocytosed by cells. mPEG750-amine can also be used to synthesize folate-conjugated polymer micelles for encapsulating the anticancer agent Camptothecin (HY-16560). Folate-conjugated polymer micelles are effective carriers for poorly soluble anticancer drugs, capable of avoiding macrophages and acting through folate receptor (FR)-mediated endocytosis to target tumor cells. mPEG750-amine can be applied to research in the field of non-viral gene delivery, as a component of gene delivery vectors, facilitating the safe and efficient delivery of nucleic acid drugs to target cells .

HY-Y0850K

Polyvinyl alcohol (Mw 31000-50000, 98-99% hydrolyzed) 3 Publications Verification PVA (Mw 31000-50000, 98-99% hydrolyzed); Poly(Ethenol) (Mw 31000-50000, 98-99% hydrolyzed)		Polymers
Polyvinyl alcohol (Mw 31000-50000, 98-99% hydrolyzed), also known as PVA, is a vinyl water-soluble polymer that can be used as a non-ionic surfactant. It can also be used as a biodegradable polymer and can be used in adhesives, coatings, textiles, ceramics and cosmetics. Polyvinyl alcohol can be used in tissue engineering by electrospinning. Polyvinyl alcohol can achieve high cellular density, infiltration, and uniform distribution, facilitating functional connections between cells. Polyvinyl alcohol can improve cell vitality through in vitro cultivation. Polyvinyl alcohol demonstrates promising inhibition of ostersarcoma cancer cells with Doxorubicin (HY-15142A) .

HY-154659

Polycarbophil		Emulsifiers Thickeners Release-retarding Agents
Polycarbophil is an orally active hydrophilic polymer. Polycarbophil achieves bioadhesion through hydrogen bonding between carboxyl groups and mucosal surfaces, and prolongs compound retention time and regulates compound release through swelling properties. Polycarbophil relieves constipation and diarrhea .

HY-Y0850N

Polyvinyl alcohol (Mw 13000-23000, 98% hydrolyzed) 3 Publications Verification PVA (Mw 13000-23000, 98% hydrolyzed); Poly(Ethenol) (Mw 13000-23000, 98% hydrolyzed)		Polymers
Polyvinyl alcohol (PVA; Poly(Ethenol)) (Mw 13000-23000, 98% hydrolyzed) , also known as PVA, is a vinyl water-soluble polymer that can be used as a non-ionic surfactant. Polyvinyl alcohol (Mw 13000-23000, 98% hydrolyzed) can also be used as a biodegradable polymer and can be used in adhesives, coatings, textiles, ceramics and cosmetics. Polyvinyl alcohol (Mw 13,000–23,000, 98% hydrolyzed) can be used in studies involving breast cancer as well as cisplatin (HY-17394)-induced sensorineural hearing loss .

HY-Y0850O

Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed) 3 Publications Verification PVA (Mw 31000-50000, 87-89% hydrolyzed); Poly(Ethenol) (Mw 31000-50000, 87-89% hydrolyzed)		Polymers
Polyvinyl alcohol (PVA; Poly (Ethenol)) (Mw 31000-50000, 87-89% hydrolyzed) is a polymer with emulsifying and stabilizing properties, with a degree of hydrolysis of 87-89%. Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed) mainly acts as a stabilizer in the preparation of nanomedicines; it not only maintains the structural integrity of PEGylated PLGA nanoparticles during double emulsion synthesis, but also facilitates the preparation of chitosan/matrine-PLGA nanoparticle aqueous solutions and lipid-polymer nanoparticles. Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed) can be widely used in research related to fields such as breast cancer .

HY-144012

DPPE-PEG2000 ammonium 16:0 PEG2000 PE ammonium; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium		Pegylated Lipids
DPPE-PEG2000 ammonium (16:0 PEG5000 PE) is a polymer-lipid conjugate and LipoParticle stabilizer with a PEG chain of 5,000 g/mol molecular weight attached to its polar head, and it can be internalized by biological membranes. DPPE-PEG2000 ammonium enables LipoParticle to maintain colloidal stability after 20-fold dilution in PBS or cell culture medium, and prevents aggregate formation during lyophilization and rehydration. DPPE-PEG2000 ammonium helps enhance the non-cytotoxic property of LipoParticle formulations against human osteoblasts. DPPE-PEG2000 ammonium serves as a PEG lipid functional end group for synthesizing liposomes (LPs), is used in the design of conjugated polymer nanoparticles, and applies to research related to bone and joint infections .

HY-W440917

DSPE-PEG5000-FITC		Pegylated Lipids Fluorescent Lipids
DSPE-PEG5000-FITC is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.

HY-144012H

DPPE-PEG5000 16:0 PEG5000 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium		Pegylated Lipids
DPPE-PEG5000 (16:0 PEG5000 PE) is a polymer-lipid conjugate and LipoParticle stabilizer with a PEG chain of 5,000 g/mol molecular weight attached to its polar head, and it can be internalized by biological membranes. DPPE-PEG5000 enables LipoParticle to maintain colloidal stability after 20-fold dilution in PBS or cell culture medium, and prevents aggregate formation during lyophilization and rehydration. DPPE-PEG5000 helps enhance the non-cytotoxic property of LipoParticle formulations against human osteoblasts. DPPE-PEG5000 serves as a PEG lipid functional end group for synthesizing liposomes (LPs), is used in the design of conjugated polymer nanoparticles, and applies to research related to bone and joint infections .

HY-155881

mPEG550-amine mPEG550-NH2		Polymers
mPEG550-amine (mPEG550-NH2) is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. mPEG550-amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems.

HY-W440914

DSPE-PEG1000-FITC		Pegylated Lipids Fluorescent Lipids
DSPE-PEG1000-FITC is an amphiphile PEG polymer which has unsaturated lipid tails. The polymer can form micelles in an aqueous solution and can be used to prepare liposome/nano particles for drug nanocarriers. . Reagent grade, for research use only.

HY-W440916

DSPE-PEG3400-FITC		Pegylated Lipids Fluorescent Lipids
DSPE-PEG3400-FITC is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.

HY-144012A

DPPE-PEG350 16:0 PEG350 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium		Pegylated Lipids
DPPE-PEG350 is a CD1d-dependent lipid antagonist thus blocking the ERK phosphorylation pathway in iNKT cells . DPPE-PEG350 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles.

HY-W440827

DOPE-PEG2000-COOH 1 Publications Verification		Pegylated Lipids
DOPE-PEG2000-COOH is a PEG polymer containing unsaturated DOPE phospholipids and carboxylic acids. DOPE-PEG2000-COOH can be used to prepare liposomes or other nanoparticles for drug delivery .

HY-143209B

DSPE-PEG3400		Pegylated Lipids
DSPE-PEG3400 is a phospholipid-PEG polymer conjugate that can be used in drug delivery applications. DSPE-PEG3400 serves as a material for preparing nanocarriers, which is used to prolong blood circulation time, enhance stability and improve encapsulation efficiency .

HY-W440833

DSPE-PEG3400-azide		Pegylated Lipids
DSPE-PEG3400-azide is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelles formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form triazole bond.

HY-176499

PLGA38000-PEG10000 1 Publications Verification		Polymers
PLGA38000-PEG10000 is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .

HY-W440910

DSPE-PEG5000-Cy3		Pegylated Lipids Fluorescent Lipids
DSPE-PEG5000-Cy3 is a phospholipid PEG polymer with Cy3 dye used in labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.

HY-155884

mPEG4000-amine mPEG4000-NH2		Polymers
mPEG4000-amine can be used to synthesize folate-conjugated polymer micelles for encapsulating anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).

HY-155880

mPEG350-amine mPEG350-NH2		Polymers
mPEG350-amine can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).

HY-155883

mPEG3400-amine mPEG3400-NH2		Polymers
mPEG3400-amine can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).

HY-W440895

DSPE-PEG1000-SH		Pegylated Lipids
DSPE-PEG1000-SH is an amphiphilic poly-PEG that can form lipid bilayers in water. This amphiphilic polymer can form lipid bilayers in aqueous solution and can be used to embed active molecules for drug delivery systems such as mRNA vaccines.

HY-W440834

DSPE-PEG5000-azide		Pegylated Lipids
DSPE-PEG5000-azide is a click chemistry reactive phospholipid polyPEG which forms lipid bilayer or micelles in an aqueous solution. The polymer can be used to prepare liposomes or nanoparticles used for delivering nutrients or therapeutic agents, for example mRNA or DNA vaccine.

HY-W250721D

Carbomer Carboxy polymethylene		Emulsifiers Suspending Agents
Carbomer (Carboxy polymethylene) is an acrylic acid polymer, which can be used as a thickening agent. Carbomer provides a stable gel matrix, exhibits good heat, light and microbial contamination resistance. Carbomer facilitates the drug release and local application, which can be used in the pharmaceutical industry .

HY-W250721G

Carbomer interpolymer Carboxy polymethylene (interpolymer)		Release-retarding Agents
Carbomer interpolymer (Carboxy polymethylene (interpolymer)) is an acrylic acid polymer, which can be used as a thickening agent. Carbomer interpolymer provides a stable gel matrix, exhibits good heat, light and microbial contamination resistance. Carbomer interpolymer facilitates the drug release and local application, which can be used in the pharmaceutical industry .

HY-W250721F

Carbomer homopolymer Carboxy polymethylene (homopolymer)		Release-retarding Agents
Carbomer homopolymer (Carboxy polymethylene (homopolymer)) is an acrylic acid polymer, which can be used as a thickening agent. Carbomer homopolymer provides a stable gel matrix, exhibits good heat, light and microbial contamination resistance. Carbomer homopolymer facilitates the drug release and local application, which can be used in the pharmaceutical industry .

HY-W250580

Dimethicone		Others
Dimethicone is an orally active biochemical assay reagents consisting of a fully methylated linear siloxane polymer whose ends are blocked by trimethylsiloxane units. Dimethicone can lubricate hair and physically block the respiratory system of lice to remove lice. Dimethicone has potential applications in cosmetics and daily cleaning products .

HY-W099569

Zinc stearate Zinc octadecanoate		Others
Zinc stearate is a metal stearate that acts as a preservative, bactericide, fungicide, and larvicide. Zinc stearate inhibits larval reproduction in animal feces. Zinc stearate exhibits extremely low systemic toxicity. Zinc stearate is a common component of pharmaceutical excipients, lubricants, mold release agents, polymer stabilizers, and coating matting agents .

HY-W591632

PEG-bis-amine (MW 1000) Poly(ethylene glycol)-bis-amine (MW 1000)		Polymers
PEG-bis-amine (MW 1000) synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).

HY-W115607

PEG4000-bis-amine Poly(ethylene glycol)-bis-amine 4000		Polymers
PEG4000-bis-amine synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).

HY-144013B

18:0 mPEG550 PE ammonium DSPE-mPEG550 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammonium		Pegylated Lipids
18:0 mPEG550 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

HY-144013A

18:0 mPEG350 PE ammonium DSPE-mPEG350 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium		Pegylated Lipids
18:0 mPEG350 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

HY-144013D

18:0 mPEG1000 PE ammonium DSPE-mPEG1000 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium		Pegylated Lipids
18:0 mPEG1000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

HY-144013E

18:0 mPEG3000 PE ammonium DSPE-mPEG3000 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium		Pegylated Lipids
18:0 mPEG3000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

HY-144013C

18:0 mPEG750 PE ammonium DSPE-mPEG750 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-750] ammonium		Pegylated Lipids
18:0 mPEG750 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

HY-N15976

DMG-pSar25 Maleimide		Pegylated Lipids
DMG-pSar25 Maleimide is a lipid conjugated to DMG, Maleimide and pSar25 polymer. DMG-pSar25 Maleimide can be used to prepare lipid nanoparticles for drug delivery.

HY-155934

18:1 PEG5000 PE ammonium DOPE-PEG5000 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium		Pegylated Lipids
18:1 PEG5000 PE ammonium (DOPE-PEG5000 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

HY-155926

DMPE-PEG750 ammonium 14:0 PEG750 PE ammonium; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-750] ammonium		Pegylated Lipids
DMPE-PEG750 ammonium (14:0 PEG750 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

HY-155924

DMPE-PEG350 ammonium 14:0 PEG350 PE ammonium; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium		Pegylated Lipids
DMPE-PEG350 ammonium (14:0 PEG350 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

HY-155927

DMPE-PEG1000 ammonium 14:0 PEG1000 PE ammonium; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium		Pegylated Lipids
DMPE-PEG1000 ammonium (14:0 PEG1000 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

HY-155925

DMPE-PEG550 ammonium 14:0 PEG550 PE ammonium; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammonium		Pegylated Lipids
DMPE-PEG550 ammonium (14:0 PEG550 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

HY-155929

DMPE-PEG5000 ammonium 14:0 PEG5000 PE ammonium; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium		Pegylated Lipids
DMPE-PEG5000 ammonium (14:0 PEG5000 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

HY-155928

DMPE-PEG3000 ammonium 14:0 PEG3000 PE ammonium; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium		Pegylated Lipids
DMPE-PEG3000 ammonium (14:0 PEG3000 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

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