165 Results for "

programmed cell death

" in MedChemExpress (MCE) Product Catalog:
Products (165)

165 Results for "programmed cell death" in MCE Product Catalog:

37
37 Publications Verification
Cat. No.: HY-P9902
CAS No.: 1374853-91-4
Synonyms: MK-3475; Lambrolizumab

Target:  

PD-1/PD-L1

Research Areas:  

Cancer

Pembrolizumab (MK-3475) is a humanized IgG4 antibody inhibiting the programmed cell death 1 (PD-1) receptor, used in cancer immunotherapy.
loading...
    loading...
24
24 Cited Publications
Cat. No.: HY-P9903
CAS No.: 946414-94-4
Synonyms: BMS-936558; ONO-4538; MDX-1106

Target:  

PD-1/PD-L1

Research Areas:  

Infection Cancer

Nivolumab is a programmed death receptor-1 (PD-1) blocking human IgG4 antibody to treat advanced (metastatic) non-small cell lung cancer.
loading...
    loading...
10
10 Cited Publications
Cat. No.: HY-P73361
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD274; B7 Homolog 1; Prev. PDCD1LG1; B7-H; PD-L1; PDCD1 Ligand 1; B7H1; PDCD1L1; PDL1; HPD-L1; programmed cell death 1 Ligand 1; programmed death Ligand 1; CD274 Antigen; ADMIO5; CD274 Molecule; B7-H1
Species:  
Human
Source:  
HEK293
loading...
    loading...
5
5 Cited Publications
Cat. No.: HY-P2149
CAS No.: 11028-71-0
Concanavalin A can be coupled to agarose to form Concanavalin A (agarose) (HY-P2149A). Concanavalin A (ConA) is a selective, competitive binding agent that targets specific carbohydrate structures containing glucose and mannose; it acts as a mitogen and exhibits varying degrees of cytotoxicity, hepatotoxicity, and teratogenicity. Concanavalin A is also utilized for in vivo blood glucose monitoring in the context of diabetes .
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-P81169A
Synonyms: programmed cell death protein 1; CD279; CD279 antigen; hPD 1; hPD-1; hSLE1; PD 1; PD1; PDCD 1; PDCD1; PDCD1_HUMAN; programmed cell death 1; Protein PD 1; Protein PD-1; SLEB2; Systemic lupus erythematosus susceptibility 2.

Host:  

Mouse

Application:  

WB, IHC-P, ICC/IF, FC

Reactivity:  

Human

loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-N0596
CAS No.: 19666-76-3
Synonyms: 20(R)-Panaxadiol
Panaxadiol (20(R)-Panaxadiol) is an orally active HIF-1α/STAT3 inhibitor. Panaxadiol can suppress HIF-1α and STAT3 then lead to downregulation of programmed cell death-ligand 1 (PD-L1) expression. Panaxadiol shows anticancer, cardioprotective, anti-arrhythmic, and antioxidative activities .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-P99052
CAS No.: 1858168-59-8
Synonyms: BGB-A317
Target:  

PD-1/PD-L1

Research Areas:  

Inflammation/Immunology Cancer

Tislelizumab is a monoclonal antibody that specifically binds to programmed cell death receptor 1 (PD-1), blocking its interaction with programmed death ligand 1 (PD-L1) and programmed death ligand 2 (PD-L2). Tislelizumab can reactivate immune cells such as T lymphocytes and enhance anti-tumor activity. Tislelizumab can be used for the research of a variety of tumors including typical Hodgkin's lymphoma, urothelial carcinoma, non-small cell lung cancer and hepatocellular carcinoma .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-P7395
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PDCD1; Systemic Lupus Erythematosus Susceptibility 2; Prev. SLEB2; HPD-1; PD1; programmed cell death 1 Protein; programmed cell death Protein 1; CD279 Antigen; CD279; ADMIO4; HSLE1; AIMTBS; PD-1; HPD-L; programmed cell death 1; Protein PD-1
Species:  
Human
Source:  
CHO
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-P70632
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD274; B7 Homolog 1; Prev. PDCD1LG1; B7-H; PD-L1; PDCD1 Ligand 1; B7H1; PDCD1L1; PDL1; HPD-L1; programmed cell death 1 Ligand 1; programmed death Ligand 1; CD274 Antigen; ADMIO5; CD274 Molecule; B7-H1
Species:  
Mouse
Source:  
HEK293
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P7396
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PDCD1; Systemic Lupus Erythematosus Susceptibility 2; Prev. SLEB2; HPD-1; PD1; programmed cell death 1 Protein; programmed cell death Protein 1; CD279 Antigen; CD279; ADMIO4; HSLE1; AIMTBS; PD-1; HPD-L; programmed cell death 1; Protein PD-1
Species:  
Human
Source:  
HEK293
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-N1990
CAS No.: 94987-08-3
Gypenoside XLIX is a multifunctional bioactive compound that can be isolated from Gynostemma pentaphyllum, with a Ka value of 1.58 μM for its binding to SIRT1. Gypenoside XLIX acts as a PPAR-α agonist. It inhibits the activation of TLR4-mediated NF-κB signaling pathway by activating the Sirt1/Nrf2 signaling pathway, reduces ROS accumulation, and alleviates hepatic inflammatory injury in mice with sepsis-induced liver disease. Gypenoside XLIX targets SIRT1 to block YAP-NLRP3 activation and improve sepsis-induced cardiomyopathy. Gypenoside XLIX inhibits apoptosis (Apoptosis), pyroptosis (Pyroptosis), autophagy (Autophagy), lipid peroxidation, pro-inflammatory cytokines and anti-inflammatory cytokines. Gypenoside XLIX alleviates sepsis-induced splenic injury by inhibiting inflammation and oxidative stress, and mitigates sepsis-associated encephalopathy by targeting PPAR-α. Gypenoside XLIX prevents acute kidney injury by inhibiting IGFBP7/IGF1R-mediated programmed cell death and inflammation. Gypenoside XLIX inhibits the expression and activity of vascular cell adhesion molecule-1 in cytokine-induced human endothelial cells. Gypenoside XLIX is applicable to research related to acute liver injury, lung injury, cardiomyopathy, acute splenic injury, sepsis-associated encephalopathy, acute kidney injury, atherosclerosis and chronic inflammation .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P70639
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PDCD1; Systemic Lupus Erythematosus Susceptibility 2; Prev. SLEB2; HPD-1; PD1; programmed cell death 1 Protein; programmed cell death Protein 1; CD279 Antigen; CD279; ADMIO4; HSLE1; AIMTBS; PD-1; HPD-L; programmed cell death 1; Protein PD-1
Species:  
Mouse
Source:  
HEK293
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P73724
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PDCD1; Systemic Lupus Erythematosus Susceptibility 2; Prev. SLEB2; HPD-1; PD1; programmed cell death 1 Protein; programmed cell death Protein 1; CD279 Antigen; CD279; ADMIO4; HSLE1; AIMTBS; PD-1; HPD-L; programmed cell death 1; Protein PD-1
Species:  
Mouse
Source:  
HEK293
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P73344A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.;≥ 90%, as determined by HPLC.
Synonyms: PDCD1; Systemic Lupus Erythematosus Susceptibility 2; Prev. SLEB2; HPD-1; PD1; programmed cell death 1 Protein; programmed cell death Protein 1; CD279 Antigen; CD279; ADMIO4; HSLE1; AIMTBS; PD-1; HPD-L; programmed cell death 1; Protein PD-1
Species:  
Human
Source:  
HEK293
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P80006
Synonyms: AIF, PDCD8, AIFM1, programmed cell death protein 8

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-P, IP, FC

Reactivity:  

Human, Mouse

loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P84982
Synonyms: programmed cell death 1 ligand 1; PD-L1; PDCD1 ligand 1; programmed death ligand 1; B7 homolog 1; B7-H1; CD antigen CD274; CD274 nanobody; PD-L1 nanobody;

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human

loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P73369
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PDCD1LG2; B7 Dendritic cell Molecule; programmed cell death 1 Ligand 2; programmed death Ligand 2; PD-L2; Butyrophilin B7-DC; CD273; PDCD1 Ligand 2; B7-DC; PDCD1L2; PDL2; PD-1-Ligand 2; B7DC; CD273 Antigen; BA574F11.2; PD-1 Ligand 2; Btdc
Species:  
Mouse
Source:  
HEK293
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P7397
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD274; B7 Homolog 1; Prev. PDCD1LG1; B7-H; PD-L1; PDCD1 Ligand 1; B7H1; PDCD1L1; PDL1; HPD-L1; programmed cell death 1 Ligand 1; programmed death Ligand 1; CD274 Antigen; ADMIO5; CD274 Molecule; B7-H1
Species:  
Human
Source:  
CHO
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P10387
Research Areas:  

Cancer

RSM3 is a METTL3-METTL14 complex inhibitor with a Kd of 3.10 μM for the METTL3-METTL14 complex. RSM3 reduces the m 6A modification level of SLC31A1 and the global RNA methylation level. RSM3 upregulates programmed cell death-related genes, enhances cell apoptosis, inhibits pro-cancer signals and suppresses tumor growth. RSM3 is applicable to the research of preeclampsia and cancer .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P10387A
Target:  

METTL3 Apoptosis

Research Areas:  

Cancer

RSM3 TFA is a METTL3-METTL14 complex inhibitor with a Kd of 3.10 μM for the METTL3-METTL14 complex. RSM3 TFA reduces the m 6A modification level of SLC31A1 and the global RNA methylation level. RSM3 TFA upregulates programmed cell death-related genes, enhances cell apoptosis, inhibits pro-cancer signals and suppresses tumor growth. RSM3 TFA is applicable to the research of preeclampsia and cancer .
loading...
    loading...