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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1219 Results for "
reducing agents
" in MedChemExpress (MCE) Product Catalog:
Products (1219)
1219 Results for "reducing agents" in MCE Product Catalog:
803
803 Publications Verification
Synonyms: N-Acetylcysteine; N-Acetyl-L-cysteine; NAC
744
744 Cited Publications
Synonyms: Hydroxydaunorubicin hydrochloride; ADR
137
137 Cited Publications
Synonyms: Methyl-beta-cyclodextrin
103
Target:
Domaines de recherche:
Pirfenidone (AMR69) is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines. Pirfenidone also has anti-inflammatory activities .
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Ciprofloxacin (Bay-09867) is an orally active, blood-brain barrier permeable fluoroquinolone antibacterial agent. Ciprofloxacin exerts bactericidal effects primarily by inhibiting topoisomerase II and IV. Ciprofloxacin inhibits the proliferation of human dental pulp stem cells and chondrocytes from young rats, and also activates the Akt signaling pathway and upregulates markers such as β-catenin and Nanog to maintain the morphological characteristics of stem cells. Ciprofloxacin induces significant neurotoxicity and tissue damage, including reducing serotonin and glutathione levels in the brain, inducing oxidative stress and depression-like behaviors, and causing articular cartilage damage. Ciprofloxacin can be applied to research related to infections of necrotic young permanent teeth and neurotoxicity .
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61 Cited Publications
Cat. No.: HY-B0356B
CAS No.: 86393-32-0
Synonyms: Bay-09867 hydrochloride monohydrate
Ciprofloxacin (Bay-09867) hydrochloride monohydrate is an orally active, blood-brain barrier permeable fluoroquinolone antibacterial agent. Ciprofloxacin hydrochloride monohydrate exerts bactericidal effects primarily by inhibiting topoisomerase II and IV. Ciprofloxacin hydrochloride monohydrate inhibits the proliferation of human dental pulp stem cells and chondrocytes from young rats, and also activates the Akt signaling pathway and upregulates markers such as β-catenin and Nanog to maintain the morphological characteristics of stem cells. Ciprofloxacin hydrochloride monohydrate induces significant neurotoxicity and tissue damage, including reducing serotonin and glutathione levels in the brain, inducing oxidative stress and depression-like behaviors, and causing articular cartilage damage. Ciprofloxacin hydrochloride monohydrate can be applied to research related to infections of necrotic young permanent teeth and neurotoxicity .
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Ciprofloxacin hydrochloride (Bay-09867 hydrochloride) is an orally active, blood-brain barrier permeable fluoroquinolone antibacterial agent. Ciprofloxacin hydrochloride exerts bactericidal effects primarily by inhibiting topoisomerase II and IV. Ciprofloxacin hydrochloride inhibits the proliferation of human dental pulp stem cells and chondrocytes from young rats, and also activates the Akt signaling pathway and upregulates markers such as β-catenin and Nanog to maintain the morphological characteristics of stem cells. Ciprofloxacin hydrochloride induces significant neurotoxicity and tissue damage, including reducing serotonin and glutathione levels in the brain, inducing oxidative stress and depression-like behaviors, and causing articular cartilage damage. Ciprofloxacin hydrochloride can be applied to research related to infections of necrotic young permanent teeth and neurotoxicity .
61
Ciprofloxacin (Bay-09867) monohydrochloride is an orally active, blood-brain barrier permeable fluoroquinolone antibacterial agent. Ciprofloxacin monohydrochloride exerts bactericidal effects primarily by inhibiting topoisomerase II and IV. Ciprofloxacin monohydrochloride inhibits the proliferation of human dental pulp stem cells and chondrocytes from young rats, and also activates the Akt signaling pathway and upregulates markers such as β-catenin and Nanog to maintain the morphological characteristics of stem cells. Ciprofloxacin monohydrochloride induces significant neurotoxicity and tissue damage, including reducing serotonin and glutathione levels in the brain, inducing oxidative stress and depression-like behaviors, and causing articular cartilage damage. Ciprofloxacin monohydrochloride can be applied to research related to infections of necrotic young permanent teeth and neurotoxicity .
59
Category:
Infection Macrolide Antibiotics Antifungal Antibiotics Mammalian Cell Culture Microorganism Disease Research Disease Research Fields
Target:
48
48 Cited Publications
Cat. No.: HY-N0176
CAS No.: 71939-50-9
Synonyms: Dihydroqinghaosu; β-Dihydroartemisinin; Artenimol
41
41 Cited Publications
Cat. No.: HY-B0330
CAS No.: 100986-85-4
Target:
Bacterial Orthopoxvirus Topoisomerase Reactive Oxygen Species (ROS) GABA Receptor PCSK9 Apoptosis
Domaines de recherche:
Levofloxacin is an orally active broad-spectrum antibacterial agent with antioxidant and antibacterial activities. Levofloxacin upregulates TC synthesis-related genes and transport-related genes, reduces plasma PCSK9, inhibits GABAA receptors and mitochondrial complexes I/III, scavenges hydroxyl radicals and neutrophil-derived ROS, and inhibits NO metabolites and interferon-γ. Levofloxacin improves survival, alleviates lung injury, and reduces oxidative and inflammatory markers in influenza virus-infected mice. Levofloxacin inhibits lung cancer proliferation and xenograft tumor growth, and induces apoptosis and oxidative stress. Levofloxacin can be used in research on bacterial infection, influenza virus infection, atherosclerosis, and lung cancer .
41
41 Cited Publications
Cat. No.: HY-B0330B
CAS No.: 177325-13-2
Target:
Bacterial Orthopoxvirus Topoisomerase Reactive Oxygen Species (ROS) GABA Receptor PCSK9 Apoptosis
Domaines de recherche:
Levofloxacin hydrochloride is an orally active broad-spectrum antibacterial agent with antioxidant and antibacterial activities. Levofloxacin hydrochloride upregulates TC synthesis-related genes and transport-related genes, reduces plasma PCSK9, inhibits GABAA receptors and mitochondrial complexes I/III, scavenges hydroxyl radicals and neutrophil-derived ROS, and inhibits NO metabolites and interferon-γ. Levofloxacin hydrochloride improves survival, alleviates lung injury, and reduces oxidative and inflammatory markers in influenza virus-infected mice. Levofloxacin hydrochloride inhibits lung cancer proliferation and xenograft tumor growth, and induces apoptosis and oxidative stress. Levofloxacin hydrochloride can be used in research on bacterial infection, influenza virus infection, atherosclerosis, and lung cancer .
41
Target:
Bacterial Orthopoxvirus Topoisomerase Reactive Oxygen Species (ROS) GABA Receptor PCSK9 Apoptosis
Domaines de recherche:
Levofloxacin hydrate (Levofloxacin hemihydrate) is an orally active broad-spectrum antibacterial agent with antioxidant and antibacterial activities. Levofloxacin hydrate upregulates TC synthesis-related genes and transport-related genes, reduces plasma PCSK9, inhibits GABAA receptors and mitochondrial complexes I/III, scavenges hydroxyl radicals and neutrophil-derived ROS, and inhibits NO metabolites and interferon-γ. Levofloxacin hydrate improves survival, alleviates lung injury, and reduces oxidative and inflammatory markers in influenza virus-infected mice. Levofloxacin hydrate inhibits lung cancer proliferation and xenograft tumor growth, and induces apoptosis and oxidative stress. Levofloxacin hydrate can be used in research on bacterial infection, influenza virus infection, atherosclerosis, and lung cancer .
40
Domaines de recherche:
Ethylenediaminetetraacetic acid (EDTA) is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid can be used for coronary artery disease and neural system disease research .
40
40 Cited Publications
Synonyms: CC-4047; Actimid
Target:
TNF Receptor Interleukin Related FOXP Orexin Receptor (OX Receptor) CDK Ligands for E3 Ligase
Domaines de recherche:
Pomalidomide (CC-4047) is an immunomodulatory agent. Pomalidomide downregulates TNF-alpha, IL-1, IL-11, and IL-12, upregulates IL-2, IL-5, and IL-10, and costimulates T cells. Pomalidomide inhibits the proliferation of T regulatory cells by reducing FOXP3/OX-40 expression and IL-2-mediated expansion. Pomalidomide inhibits CDK2/4/6 and p21WAF-1, causing cell cycle arrest. Pomalidomide can be used in research on myelofibrosis-associated anemia, multiple myeloma, and colorectal cancer .
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Category:
37
37
37 Cited Publications
Synonyms: RR82 hydrochloride
Domaines de recherche:
Pyridostatin (RR82) hydrochloride is a G-quadruplex DNA stabilizing agent (Kd=490 nM) and can target DNA and RNA G4s in cells. Pyridostatin hydrochloride promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin hydrochloride targets the proto-oncogene Src. Pyridostatin hydrochloride reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells .
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37 Cited Publications
Cat. No.: HY-B0013
CAS No.: 294662-18-3
Target:
Bacterial Orthopoxvirus Topoisomerase Reactive Oxygen Species (ROS) GABA Receptor PCSK9 Apoptosis
Domaines de recherche:
Levofloxacin lactate is an orally active broad-spectrum antibacterial agent with antioxidant and antibacterial activities. Levofloxacin lactate upregulates TC synthesis-related genes and transport-related genes, reduces plasma PCSK9, inhibits GABAA receptors and mitochondrial complexes I/III, scavenges hydroxyl radicals and neutrophil-derived ROS, and inhibits NO metabolites and interferon-γ. Levofloxacin lactate improves survival, alleviates lung injury, and reduces oxidative and inflammatory markers in influenza virus-infected mice. Levofloxacin lactate inhibits lung cancer proliferation and xenograft tumor growth, and induces apoptosis and oxidative stress. Levofloxacin lactate can be used in research on bacterial infection, influenza virus infection, atherosclerosis, and lung cancer .
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36 Cited Publications
Synonyms: EDTA trisodium salt; Trisodium EDTA
Domaines de recherche:
Ethylenediaminetetraacetic acid trisodium salt (EDTA trisodium salt; Trisodium EDTA) is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid trisodium salt has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid trisodium salt decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid trisodium salt can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid can be used for coronary artery disease and neural system disease research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
