Anticancer agent 223
Anticancer agent 223 (Compound V-d) is an anticancer agent that triggers cell death through caspase-dependent and caspase-independent mechanisms. Anticancer agent 223 inhibits tumor spheroid formation and resensitizes cisplatin (HY-17394)-resistant A2780 cells to cisplatin (HY-17394) treatment.
For research use only. We do not sell to patients.
- CAS No.: 1328150-75-9
- Formula: C20H19ClN4O
- Molecular Weight:366.84
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A2780 | IC50 |
5.68 μM
Compound: V-d
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Antiproliferative activity against human A2780 cells assessed as cell viability incubated for 72 hrs by CCK8 assay
Antiproliferative activity against human A2780 cells assessed as cell viability incubated for 72 hrs by CCK8 assay
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[PMID: 38754563] |
| HK-2 | IC50 |
>50 μM
Compound: V-d
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Cytotoxicity against HK-2 cells
Cytotoxicity against HK-2 cells
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[PMID: 38754563] |
Chemical Information
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CAS No. 1328150-75-9
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Molecular Weight 366.84
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Formula C20H19ClN4O
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SMILES
ClC1=CC=C(NC(C2CCN(C3=NC=NC4=C3C=CC=C4)CC2)=O)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anticancer agent 223 Related Classifications
HY-161661 Related Classifications
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