YKL-05-093
YKL-05-093 is a salt-induced kinase (SIK) inhibitor (SIK2: Kd = 7.1 nM). YKL-05-093 reduces the phosphorylation level of HDAC4/5/CRTC2, inhibits SOST expression, and stimulates RANKL expression in vitro and in vivo. YKL-05-093 can be used in research on bone diseases.
For research use only. We do not sell to patients.
- CAS No.: 2172616-44-1
- Formula: C35H40N6O4
- Molecular Weight:608.73
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 2172616-44-1
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Molecular Weight 608.73
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Formula C35H40N6O4
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SMILES
O=C1N(C2=CC=C(C=C2OC)OC)C3=NC(NC4=CC=C(C5CCN(CC5)C)C(OC)=C4)=NC=C3CN1C6=C(C)C=CC=C6C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)