YKL-05-093
YKL-05-093 is a salt-induced kinase (SIK) inhibitor (SIK2: Kd = 7.1 nM). YKL-05-093 reduces the phosphorylation level of HDAC4/5/CRTC2, inhibits SOST expression, and stimulates RANKL expression in vitro and in vivo. YKL-05-093 can be used in research on bone diseases.
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- CAS. Nr.: 2172616-44-1
- Formel: C35H40N6O4
- Molecular Weight:608.73
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 2172616-44-1
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Molecular Weight 608.73
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Formel C35H40N6O4
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SMILES
O=C1N(C2=CC=C(C=C2OC)OC)C3=NC(NC4=CC=C(C5CCN(CC5)C)C(OC)=C4)=NC=C3CN1C6=C(C)C=CC=C6C
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)