1. Apoptosis
  2. Caspase

ML132 (Synonyms: NCGC 00185682)

Cat. No.: HY-12412
Handling Instructions

ML132 (NCGC 00185682) is a potent and selective caspase 1 inhibitor with an IC50 of 0.316 nM.

For research use only. We do not sell to patients.

ML132 Chemical Structure

ML132 Chemical Structure

CAS No. : 1230628-71-3

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Description

ML132 (NCGC 00185682) is a potent and selective caspase 1 inhibitor with an IC50 of 0.316 nM.

IC50 & Target

IC50: 0.316 nM (Caspase 1)[1]

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0923 mL 10.4616 mL 20.9231 mL
5 mM 0.4185 mL 2.0923 mL 4.1846 mL
10 mM 0.2092 mL 1.0462 mL 2.0923 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

477.94

Formula

C₂₂H₂₈ClN₅O₅

CAS No.

1230628-71-3

SMILES

ClC1=CC(C(N[[email protected]@H](C(C)(C)C)C(N2CCC[[email protected]]2C(N[[email protected]@H](CC(O)=O)C#N)=O)=O)=O)=CC=C1N

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
ML132
Cat. No.:
HY-12412
Quantity:

ML132

Cat. No.: HY-12412