Antibiotic
Antibiotics are a class of secondary metabolites produced from microorganisms, animals or plants. Some of them exhibit anti-bacterial, anti-fungal, anthelmintic, anti-tumor or immunosuppressive activities with a wealth of structural classes such as β-lactams, macrolide and polyether. As major sources of antibiotics, streptomycetes, penicillium and marine organisms produce a wide variety of commercially important polyketide compounds including the well-known macrolide, polyene and polyether antibiotics with wide range of activities. Antibiotics such as penicillin, cephalosporin, streptomycin, and tetracycline can be used in the treatment of human and veterinary diseases. However, antibiotic resistance is also a growing threat to global public health.
Antibiotic Isoform Specific Products
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Antibiotic
(2782)
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Aminoglycoside
(46)
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Glycopeptide
(19)
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Lipopeptide
(7)
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Macrolide
(76)
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Oxazolidinone
(16)
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Quinolone
(101)
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Tetracycline
(42)
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β-lactam
(199)
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All Product Categories
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Antibiotic Related Products (3548)
Related Products (3548)
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Related Compound Screening Libraries (1)
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Antibiotic Isoform Comparison
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Lactoquinomycin B
0 ImagesCat. No.: HY-N14774CAS No.: 101342-94-3Lactoquinomycin B is a quinone antibiotic. Lactoquinomycin B has the activity of anti-Gram-positive bacteria and some Gram-negative bacteria, but the effect of anti-Gram-negative bacteria is weak and has no effect on fungi. Lactoquinomycin B inhibits a variety of cell lines including lymphoma L5178Y progenitor, Adriamycin resistant, Bleomycin-resistant, human leukemia K562, mouse leukemia L-1210 and mouse leukemia P 388 with ID50 (μg/mL) of 0.43, 0.21, 0.19, 0.16, 0.2 and 0.12, respectively.
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Elmycin D
0 ImagesCat. No.: HY-N13019CAS No.: 169107-03-3Elmycin D is an antibiotic, which can be isolated from Streptomyces cellulosae ssp. griseoincarnatus.
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Nitrofurazone (Standard)
0 ImagesNitrofurazone (Standard) is the analytical standard of Nitrofurazone. This product is intended for research and analytical applications. Nitrofurazone (Nitrofural) is a broad spectrum antibiotic that has oral activity. Nitrofurazone is a nitro-aromatic drug. Nitrofurazone is active against both Gram-positive and Gram-negative bacteria.
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Sulfaclozine sodium (Standard)
0 ImagesSynonyms: Sulfachloropyrazine sodium (Standard)Sulfaclozine (sodium) (Standard) is the analytical standard of Sulfaclozine (sodium). This product is intended for research and analytical applications. Sulfaclozine sodium (Sulfachloropyrazine sodium) is an efficacious sulphonamide derivative with antibacterial and anticoccidial effects. Sulfaclozine sodium is commonly used for the treatment of various poultry diseases (particularly, collibacteriosis, fowl cholera and coccidiosis).
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Bacampicillin (hydrochloride) (Standard)
0 ImagesCat. No.: HY-B1149ARCAS No.: 37661-08-8Bacampicillin (hydrochloride) (Standard) is the analytical standard of Bacampicillin hydrochloride (HY-B1149A). This product is intended for research and analytical applications. Bacampicillin hydrochloride is an orally active semi-synthetic aminopenicillin derivative, prodrug and bactericide that is readily inactivated by β-lactamases. Bacampicillin hydrochloride is hydrolyzed by carboxylester hydrolases and non-specific esterases in the gastrointestinal wall and plasma to form Ampicillin (HY-B0522), and produces higher levels of Ampicillin in rodents in vivo. Bacampicillin hydrochloride exhibits bactericidal activity against Gram-positive and Gram-negative bacteria. Bacampicillin hydrochloride can be used in studies related to bacterial infections.
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Ezomycin D2
0 ImagesCat. No.: HY-N14283CAS No.: 57973-11-2Ezomycin D2 is an antifungal antibiotic. Ezomycin D2 is mainly active against phytopathogens such as Sclerotinia sclerotiorum and Botrytis, and has a control effect on Sclerotinia, Botrytis and Candidiasis of crops.
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2-Hydroxygentamicin C1
0 ImagesCat. No.: HY-N14704CAS No.: 60609-40-72-Hydroxygentamicin C1 is an antibiotic of the gentamicin group with anti-Gram-positive and negative bacteria activity.
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Milbemycin α13
0 ImagesCat. No.: HY-N15094CAS No.: 123123-62-6Synonyms: Meilingmycin BMilbemycin α13 (Meilingmycin B) is an antibiotic and has the effect of killing nematodes and mites.
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Oritavancin diphosphate (Standard)
0 ImagesSynonyms: LY333328 diphosphate (Standard)Oritavancin (diphosphate) (Standard) is the analytical standard of Oritavancin (diphosphate). Oritavancin diphosphate (Standard), a semisynthetic derivative of Vancomycin (HY-B0671), is an orally active glycopeptide antibiotic with bactericidal activity against gram-positive organisms. Oritavancin diphosphate (Standard) shows antibacterial effect against B. anthracis, such as Ames strain with a MIC value of 0.015 g/mL. Oritavancin diphosphate (Standard) inhibits cell wall synthesis and disrupts the membrane potential. Oritavancin diphosphate (Standard) inhibits ArlS kinase activity thereby interfering the signal transduction. Oritavancin diphosphate (Standard) enters cells by adsorptive endocytosis, which drives it to lysosomes, where it exerts antibiotic activity.
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Antibiotic adjuvant 5
0 ImagesCat. No.: HY-182675CAS No.: 2292113-87-0Antibiotic adjuvant 5 (Compound 2) acts as an Antibiotic adjuvant. Antibiotic adjuvant 5 enhances the activity of Azithromycin (HY-17506), Clarithromycin (HY-17508), Doripenem (HY-B0187) and Rifampin (HY-B0272) against *Pseudomonas aeruginosa* PAO1. When used in combination with Azithromycin, Antibiotic adjuvant 5 increases the survival rate of *Galleria mellonella* during *Pseudomonas aeruginosa* PAO1 infection. Antibiotic adjuvant 5 is applicable for the research of *Pseudomonas aeruginosa* infection.
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Lactonamycin Z
0 ImagesCat. No.: HY-N15392CAS No.: 709032-67-7Lactonamycin Z is an antitumor antibiotic. Lactonamycin Z has weak anti-Gram-positive bacterial activity. Lactonamycin Z can inhibit human tumor cells HMO2, MCF7 and Hep G2 with GI50 (μg/mL) of 1.9, 0.85 and 5.11, respectively.
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Chlorhexidine dihydrochloride (Standard)
0 ImagesChlorhexidine dihydrochloride (Standard) is the analytical standard of Chlorhexidine dihydrochloride (HY-B1145). This product is intended for research and analytical applications. Chlorhexidine dihydrochloride is a orally active cationic antimicrobial agent that targets microbial cell membranes. Chlorhexidine dihydrochloride binds to cell membrane phospholipids non-specifically, destroys membrane structure and induces leakage of cell contents. Chlorhexidine dihydrochloride has broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. Chlorhexidine dihydrochloride can interfere with membrane permeability, cause protein precipitation and energy metabolism disorders, such as rapid inhibition of microbial growth and induction of cell death (necrosis or apoptosis).
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Dynemicin A
0 ImagesCat. No.: HY-N13726CAS No.: 124412-57-3Dynemicin A is a potent antitumor antibiotic. Dynemicin A is a DNA synthesis inhibitor with an IC50 of 2.2 ng/mL. Dynemicin A undergoes bioreductive epoxide ring opening and Bergman cyclization to generate a highly reactive benzenoid diradical, which specifically induces double-strand DNA cleavage. Dynemicin A can be used for research on bacterial infections, leukemia, and melanoma.
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21-Hydroxyoligomycin A
0 ImagesCat. No.: HY-112541CAS No.: 102042-09-121-Hydroxyoligomycin A is a potent inhibitor of K-Ras PM localization with an IC50 value of 4.82 nM. 21-Hydroxyoligomycin A has cytotoxicity and can be isolated from Streptomyces.
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Liriodenine methiodide
0 ImagesCat. No.: HY-N7784CAS No.: 55974-07-7Liriodenine methiodide is an antibiotic that is active against C. albicans and S. cereuisiae with antimicrobial activities.
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Sulfisomidin-d4
0 ImagesCat. No.: HY-W719074CAS No.: 2732915-77-2Synonyms: Sulfaisodimidine-d4Sulfisomidin-d4 (Sulfaisodimidine-d4) is deuterium labeled Sulfisomidin. Sulfisomidin (Sulfaisodimidine) is an orally active short-acting sulfonamide antibacterial. Sulfisomidin can be used for the research of lower urinary tract infections.
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5-Hydroxymethylblasticidin S
0 ImagesCat. No.: HY-N14800CAS No.: 123067-52-75-Hydroxymethylblasticidin S is a broad-spectrum antibiotic found in Streptomyces setonii.
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Netilmicin sulfate (Standard)
0 ImagesSynonyms: SCH-20569 sulfate (Standard)Netilmicin sulfate (Standard) is the analytical standard of Netilmicin sulfate (HY-A0086). This product is intended for research and analytical applications. Netilmicin (Sch 20569) sulfate is a broad-spectrum semisynthetic aminoglycoside antibiotic. Netilmicin sulfate exhibits antibacterial activity against aminoglycoside-susceptible gram-negative strains and aminoglycoside-resistant strain, such as Escherichia coli, Pseudomonas aeruginosa, Proteus, Staphylococcus aureus, Streptococcus, Serratia, and Enterobacter, with MIC of 0.125-8 μg/mL.
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(Rac)-Luliconazole
0 ImagesCat. No.: HY-115441CAS No.: 101530-21-6Synonyms: (Rac)-NND 502(Rac)-Luliconazole ((Rac)-NND 502) is the racemic isomer of Luliconazole (HY-14283). Luliconazole is a topical antifungal imidazole antibiotic with broad-spectrum and potent antifungal activity.
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Prothracarcin
0 ImagesCat. No.: HY-129252CAS No.: 81542-99-6Prothracarcin is an antibiotic with antitumor activity that exerts its tumor cell toxicity by covalently binding to the C-2 amino group of guanine residues in the minor groove of DNA. Prothracarcin also shows antibacterial activity against Gram-positive bacteria and some Gram-negative bacteria such as Escherichia coli.
