FS102
FS102 is a selective Fc fragment with antigen binding (Fcab) that targets HER2 with a KD value of 0.8 nM. FS102 induces the degradation of HER2, activates Caspase 3/7 and disrupts the integrity of the cell membrane, triggering apoptosis of tumor cells. FS102 is promising for research of cancers such as breast cancer, gastric cancer, and colorectal cancer.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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- Reinheit & Dokumentation
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Help & FAQs
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Biologische Aktivität
Beschreibung
Species Reactivity
Human
IC50 & Target
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Caspase 3 |
Caspase-7 |
HER2 0.8 nM (Kd) |
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Gene ID
Accession
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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Product Image
Anwendung
ELISA, FACS, Functional assay
Chemical Information
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SMILES
FS(=S)(S(=S)(S(=S)(S(=S)(S(=S)(S(=S)(S(=S)(S(=S)(S(=S)(S(=S)(S(=S)(S(=S)(S(=S)(S(=S)(S(=S)(S(=S)(S(=S)(S(=S)(S(=S)(S(=S)(S(=S)(S(=S)(S(=S)(S(=S)(S(=S)(S(=S)(S(=S)(S(=S)(S(=S)(S(=S)(S(=S)(S(=S)(S(=S)([S](=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S
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Synonyms
BMS-986186
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
FS102 Related Classifications
HY-P991235 Related Classifications
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