ZDLD13
ZDLD13, a β-carboline, is an orally active and selective CDK4/CycD3 inhibitor with an IC50 value of 0.38 μM. ZDLD13 exhibits potent anti-HCT116 activity including inhibition of colony formation, inhibition of invasion and migration, inducing of apoptosis, and arresting of G1 phase in cell cycle. ZDLD13 shows significant tumor growth inhibition in HCT116 tumor xenograft model.
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- CAS. Nr.: 2762278-95-3
- Formel: C18H14N4O
- Molecular Weight:302.33
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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CDK4/CycD3 0.38 μM (IC50) |
Chemical Information
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CAS. Nr. 2762278-95-3
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Molecular Weight 302.33
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Formel C18H14N4O
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SMILES
O=C(C1=NC=CC2=C1NC3=C2C=CC=C3)NCC4=NC=CC=C4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
ZDLD13 Related Classifications
HY-115908 Related Classifications
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