Etoposide-d4
Based on 1 Customer Validation
Etoposide-d4 (VP-16-d4; VP-16-213-d4) is the deuterium labeled Etoposide (HY-13629). Etoposide (VP-16; VP-16-213) is an anti-cancer chemotherapy agent. Etoposide inhibits topoisomerase II, thus stopping DNA replication. Etoposide induces cell cycle arrest, apoptosis and autophagy.
For research use only. We do not sell to patients.
- Formula: C29H28D4O13
- Molecular Weight:592.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 33419-42-0
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Molecular Weight 592.58
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Formula C29H28D4O13
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SMILES
OC1=C(C=C(C=C1OC)[C@H]2[C@H]3C(OC[C@@H]3[C@@H](C4=C2C=C5C(OCO5)=C4)O[C@H]6[C@@H]([C@H]([C@H]7[C@H](O6)CO[C@@](C([2H])([2H])[2H])(O7)[2H])O)O)=O)OC
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Synonyms
VP-16-d4; VP-16-213-d4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)