Naltriben
Based on 3 publication(s) in Google Scholar
Naltriben is a selective δ2-opioid receptor antagonist and TRPM7 activator. Naltriben enhances glioblastoma cell migration and invasion. Naltriben can be used in research into neurological diseases and cancer.
For research use only. We do not sell to patients.
- CAS No.: 111555-58-9
- Formula: C26H25NO4
- Molecular Weight:415.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) Naltriben
MoreAll Opioid Receptor Isoforms
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Biological Activity
Chemical Information
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CAS No. 111555-58-9
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Molecular Weight 415.48
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Formula C26H25NO4
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SMILES
O[C@@]1(CC(C(C=CC=C2)=C2O3)=C3[C@]4([H])OC5=C6O)[C@]74C5=C(C=C6)C[C@@]1([H])N(CC8CC8)CC7
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (3)
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Journal Impact Factor
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Most Recent
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Nat Immunol
Lipid asymmetry disruption by XKR8 orchestrates neutrophil extracellular trap formation and inhibits fungal infection. [Abstract]2026 May;27(5):949-960. PMID: 41781710 -
Eur J Pharmacol
Blockade of KCa3.1 ameliorates rheumatoid arthritis by suppressing macrophage M1 polarization via the NLRP3 inflammasome signaling pathway. [Abstract]2026 Mar 28:1019:178738. PMID: 41794275 -
Int Immunopharmacol
TRPM7 inhibition alleviates acute gouty arthritis in mice by suppressing M1 polarization through the EDN1/EDNRB axis. [Abstract]2026 Jun 15:179:116624. PMID: 42000473
Purity & Documentation
References
[1]. Lever JR, et al. Selective in vivo binding of [3H]naltriben to delta-opioid receptors in mouse brain. Eur J Pharmacol. 1998 Jun 5;350(2-3):335-44. [Content Brief]
[2]. Wong R, et al. Activation of TRPM7 by naltriben enhances migration and invasion of glioblastoma cells. Oncotarget. 2017 Feb 14;8(7):11239-11248. [Content Brief]
Calculators
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