Anticancer agent 273
Anticancer agent 273 (Compound 9q) is a potent anticancer agent found in matrine. Anticancer agent 273 inhibits the proliferation of cancer cells (e.g., HeLa cells with an IC50 value of 4.48 μM). Anticancer agent 273 exerts anticancer effects by modulating the expression of PI3K/AKT and activating transcription factor 4 (ATF4), which promotes endoplasmic reticulum stress and induces apoptosis. Anticancer agent 273 is promising for research of cancers, such as cervical cancer.
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- Formule: C33H34N4O3
- Masse moléculaire:534.65
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Chemical Information
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Masse moléculaire 534.65
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Formule C33H34N4O3
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SMILES
[H][C@@]12CCCN3CCC[C@@]([C@@]31[H])([C@]4(CC/C(C(N4C2)=O)=C\OC(C5=CN(C6=C5C=CC=C6)CC7=CC=CC=C7C#N)=O)[H])[H]
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)