dBAZ2
dBAZ2 is a first-in-class BAZ2A and BAZ2B PROTAC degrader with DC50 values of 180 nM and 250 nM for BAZ2A and BAZ2B, respectively. (Blue: E3 ligase ligand (VH 101, thiol (HY-47851); Black: linker (HY-168450); pink: target protein ligand (HY-168449)).
(Pink: BAZ2A and BAZ2B ligand (HY-168449); Blue: VHL ligand (HY-47851); Black: linker (HY-168450)).
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- CAS No.: 3104449-57-9
- Formule: C54H64FN11O5S2
- Masse moléculaire:1030.29
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Chemical Information
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Activité biologique
Chemical Information
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CAS No. 3104449-57-9
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Masse moléculaire 1030.29
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Formule C54H64FN11O5S2
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SMILES
CC1=C(SC=N1)C2=CC=C(C=C2)CNC([C@@H]3C[C@H](CN3C([C@H](C(C)(SC[C@H]4CC[C@@H](CC4)COCC5=NC(C6=CN(N=C6)C)=C(N5CCC7=CN(N=C7)C)C8=CC=C(C=C8)C#N)C)NC(C9(CC9)F)=O)=O)O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
dBAZ2 Related Classifications
HY-168448 Related Classifications
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