Largazole thiol
Largazole thiol, the active form of Largazole (HY-13906), is a potent, selective and brain-penetrant class I HDAC inhibitor. Largazole thiol. Largazole thiol exerts antitumor and neuroprotective effects. Largazole thiol can be used for research of Glioblastoma.
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- CAS No.: 1132667-11-8
- Formule: C21H28N4O4S3
- Masse moléculaire:496.67
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
5.9 nM
Compound: 2
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Antiproliferative activity against human HCT116 cells after 48 hrs in absence of DTT by MTT assay
Antiproliferative activity against human HCT116 cells after 48 hrs in absence of DTT by MTT assay
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[PMID: 25147612] |
Chemical Information
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CAS No. 1132667-11-8
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Masse moléculaire 496.67
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Formule C21H28N4O4S3
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SMILES
C[C@@]12N=C(SC2)C3=CSC(CNC(C[C@H](OC([C@H](NC1=O)C(C)C)=O)/C=C/CCS)=O)=N3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Largazole thiol Related Classifications
HY-170890 Related Classifications
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