Martinostat
Martinostat is a HDAC inhibitor and can be labeled with radionuclides for quantitative imaging of HDACs in vivo in the central nervous system and major peripheral organs.
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- CAS No.: 1629052-58-9
- Formule: C22H30N2O2
- Masse moléculaire:354.49
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Chemical Information
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CAS No. 1629052-58-9
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Masse moléculaire 354.49
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Formule C22H30N2O2
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SMILES
CN(CC(C=C1)=CC=C1/C=C/C(NO)=O)CC2(C[C@@H](C3)C4)C[C@@H]4C[C@@H]3C2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Changning Wang, et al. In Vivo Imaging of Histone Deacetylases (HDACs) in the Central Nervous System and Major Peripheral Organs. J Med Chem. 2014 Oct 9;57(19):7999-8009. [Content Brief]
[2]. Tharick A Pascoal, et al. [11C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer’s disease. Nat Commun. 2022 Jul 19;13(1):4171. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)