2. Cell Cycle/DNA Damage
  3. CDK
  4. CDK9-IN-26

CDK9-IN-26 (compound 1is a CDK9 inhibitor (IC50=0.18 μM). .

For research use only. We do not sell to patients.

CDK9-IN-26

CDK9-IN-26 Chemical Structure

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CDK9-IN-26 Related Antibodies

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Description

CDK9-IN-26 (compound 1is a CDK9 inhibitor (IC50=0.18 μM). [1].

IC50 & Target

IC50: 0.18 μM (CDK9)[1]
Cellular Effect
Cell Line Type Value Description References
HCT-116 IC50
11.62 μM
Compound: 63; Cpd 1d
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
[PMID: 38564299]
K562 IC50
11.62 μM
Compound: 63; Cpd 1d
Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
[PMID: 38564299]
MCF7 IC50
11.62 μM
Compound: 63; Cpd 1d
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
[PMID: 38564299]
Molecular Weight

306.32

Formula

C17H14N4O2
SMILES

COC1=CC=C(NC2=C(C3=COC=C3)N=C4C=NC=CN42)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CDK9-IN-26 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CDK9-IN-26CDKCyclin dependent kinase229ECOVID-19coronaviruscyclin-dependent kinasekinase inhibitorInhibitorinhibitorinhibit

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HY-155844
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