CDK9-IN-26
CDK9-IN-26 (compound 1is a CDK9 inhibitor (IC50=0.18 μM). .
For research use only. We do not sell to patients.
- Formula: C17H14N4O2
- Molecular Weight:306.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 0.18 μM (CDK9)[1]
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
11.62 μM
Compound: 63; Cpd 1d
|
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 38564299] |
| K562 | IC50 |
11.62 μM
Compound: 63; Cpd 1d
|
Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 38564299] |
| MCF7 | IC50 |
11.62 μM
Compound: 63; Cpd 1d
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 38564299] |
Chemical Information
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Molecular Weight 306.32
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Formula C17H14N4O2
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SMILES
COC1=CC=C(NC2=C(C3=COC=C3)N=C4C=NC=CN42)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)