Etoposide-d4
Etoposide-d4 (VP-16-d4; VP-16-213-d4) is the deuterium labeled Etoposide (HY-13629). Etoposide (VP-16; VP-16-213) is an anti-cancer chemotherapy agent. Etoposide inhibits topoisomerase II, thus stopping DNA replication. Etoposide induces cell cycle arrest, apoptosis and autophagy.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C29H28D4O13
- Molecular Weight:592.58
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Protokoll
- Reinheit & Dokumentation
-
Help & FAQs
Alle Antibiotic Isoform-spezifische Produkte anzeigen
MoreAlle Topoisomerase Isoform-spezifische Produkte anzeigen
More
Biologische Aktivität
Beschreibung
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
- Detection of Apoptosis
- TUNEL staining for apoptotic DNA fragmentation
- PCNA Immunodetection Proliferation Assay
- Flow cytometric DNA-content cell-cycle staining
- Annexin V plus membrane-impermeant dye apoptosis staining
- BrdU Incorporation Assay
- Autophagy
- Apoptosis Solutions
- Protocol for Cell Cycle
- Lysosome and acidic-vesicle live-cell staining
- Macroautophagy Solutions
Anwendung
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
Unlabeled CAS 33419-42-0
-
Molecular Weight 592.58
-
Formel C29H28D4O13
-
SMILES
OC1=C(C=C(C=C1OC)[C@H]2[C@H]3C(OC[C@@H]3[C@@H](C4=C2C=C5C(OCO5)=C4)O[C@H]6[C@@H]([C@H]([C@H]7[C@H](O6)CO[C@@](C([2H])([2H])[2H])(O7)[2H])O)O)=O)OC
-
Synonyms
VP-16-d4; VP-16-213-d4
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Etoposide-d4 Related Classifications
HY-W744243 Related Classifications
Powered by Bioz