HRG038
HRG038 is a selective covalent BRD4 degrader. HRG038 binds covalently to the E3 ubiquitin ligase CUL4 DCAF16, recruiting it to BRD4, leading to the ubiquitination and subsequent proteasomal degradation of BRD4. HRG038 is promising for research of cancers.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C34H31Cl2N11O3S
- Molecular Weight:744.65
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Chemical Information
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Molecular Weight 744.65
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Formel C34H31Cl2N11O3S
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SMILES
CC(N1C(S2)=C(C(C3=CC=C(Cl)C=C3)=N4)C(C)=C2C)=NN=C1[C@@H]4CC(N(CC5)CCN5C(/C=C/C(NC(C=N6)=CC(Cl)=C6N7N=CC=N7)=O)=O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)