Largazole thiol
Largazole thiol, the active form of Largazole (HY-13906), is a potent, selective and brain-penetrant class I HDAC inhibitor. Largazole thiol. Largazole thiol exerts antitumor and neuroprotective effects. Largazole thiol can be used for research of Glioblastoma.
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- CAS. Nr.: 1132667-11-8
- Formel: C21H28N4O4S3
- Molecular Weight:496.67
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
5.9 nM
Compound: 2
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Antiproliferative activity against human HCT116 cells after 48 hrs in absence of DTT by MTT assay
Antiproliferative activity against human HCT116 cells after 48 hrs in absence of DTT by MTT assay
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[PMID: 25147612] |
Chemical Information
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CAS. Nr. 1132667-11-8
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Molecular Weight 496.67
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Formel C21H28N4O4S3
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SMILES
C[C@@]12N=C(SC2)C3=CSC(CNC(C[C@H](OC([C@H](NC1=O)C(C)C)=O)/C=C/CCS)=O)=N3
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Largazole thiol Related Classifications
HY-170890 Related Classifications
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