ZDLD13
ZDLD13, a β-carboline, is an orally active and selective CDK4/CycD3 inhibitor with an IC50 value of 0.38 μM. ZDLD13 exhibits potent anti-HCT116 activity including inhibition of colony formation, inhibition of invasion and migration, inducing of apoptosis, and arresting of G1 phase in cell cycle. ZDLD13 shows significant tumor growth inhibition in HCT116 tumor xenograft model.
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- CAS No.: 2762278-95-3
- Formule: C18H14N4O
- Masse moléculaire:302.33
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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CDK4/CycD3 0.38 μM (IC50) |
Chemical Information
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CAS No. 2762278-95-3
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Masse moléculaire 302.33
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Formule C18H14N4O
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SMILES
O=C(C1=NC=CC2=C1NC3=C2C=CC=C3)NCC4=NC=CC=C4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ZDLD13 Related Classifications
HY-115908 Related Classifications
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