Funalenone
Funalenone (BMS-304245) is a MraY + MurG inhibitor with an IC50 of 25.5 μM in a MraY + MurG membrane plate assay. Funalenone inhibits Staphylococcus aureus (A15090) with an MIC of 64 μg/mL. Funalenone also inhibits MMP-1 with an IC50 of 170 μM.
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- No. CAS: 259728-61-5
- Fòrmula: C15H12O6
- Peso molecular:288.25
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
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collagenases 1 |
HIV Integrase 10 μM (IC50) |
Chemical Information
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No. CAS 259728-61-5
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Peso molecular 288.25
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Fòrmula C15H12O6
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SMILES
O=C1C(OC)=C(O)C2=C3C1=C(O)C=C(O)C3=C(C)C=C2O
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Synonyms
BMS-304245
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
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Ficha de datos (273 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. J Inokoshi, et al. Funalenone, a novel collagenase inhibitor produced by Aspergillus niger. J Antibiot (Tokyo). 1999 Dec;52(12):1095-100. [Content Brief]
[2]. Zawadzke LE, et al. Targeting the MraY and MurG bacterial enzymes for antimicrobial therapeutic intervention. Anal Biochem. 2003 Mar 15;314(2):243-52. [Content Brief]
[3]. Kazuro Shiomi, et al. Fungal phenalenones inhibit HIV-1 integrase. J Antibiot (Tokyo). 2005 Jan;58(1):65-8. [Content Brief]
[4]. Inokoshi J, et al. Funalenone, a novel collagenase inhibitor produced by Aspergillus niger. J Antibiot (Tokyo). 1999 Dec;52(12):1095-100. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Funalenone Related Classifications
HY-121096 Related Classifications
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