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Cat. No.: HY-121096

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Funalenone

(Synonyms: BMS-304245)

Funalenone (BMS-304245) is a MraY + MurG inhibitor with an IC₅₀ of 25.5 μM in a MraY + MurG membrane plate assay. Funalenone inhibits Staphylococcus aureus (A15090) with an MIC of 64 μg/mL. Funalenone also inhibits MMP-1 with an IC₅₀ of 170 μM.

For research use only. We do not sell to patients.

CAS No.: 259728-61-5
Formula: C₁₅H₁₂O₆
Molecular Weight:288.25

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

Funalenone Chemical Structure

CAS No.: 259728-61-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target^[1]^[2]

collagenases 1

HIV Integrase

10 μM (IC₅₀)

All MMP Isoforms :

Chemical Information

CAS No. 259728-61-5
Molecular Weight 288.25
Formula C₁₅H₁₂O₆
SMILES

O=C1C(OC)=C(O)C2=C3C1=C(O)C=C(O)C3=C(C)C=C2O
Synonyms

BMS-304245
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. J Inokoshi, et al. Funalenone, a novel collagenase inhibitor produced by Aspergillus niger. J Antibiot (Tokyo). 1999 Dec;52(12):1095-100. [Content Brief]

[2]. Zawadzke LE, et al. Targeting the MraY and MurG bacterial enzymes for antimicrobial therapeutic intervention. Anal Biochem. 2003 Mar 15;314(2):243-52. [Content Brief]

[3]. Kazuro Shiomi, et al. Fungal phenalenones inhibit HIV-1 integrase. J Antibiot (Tokyo). 2005 Jan;58(1):65-8. [Content Brief]

[4]. Inokoshi J, et al. Funalenone, a novel collagenase inhibitor produced by Aspergillus niger. J Antibiot (Tokyo). 1999 Dec;52(12):1095-100. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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Funalenone

All MMP Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Funalenone Related Classifications

HY-121096 Related Classifications