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Referencia número: HY-114396

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BR351

BR351 is a brain penetrant MMP inhibitor with IC₅₀s of 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13, respectively.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 960113-85-3
Fòrmula: C₂₀H₂₅FN₂O₅S
Peso molecular:424.49

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

BR351 Chemical Structure

No. CAS: 960113-85-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- IC₅₀ & Target
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
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Actividad biológica

Descripciòn

BR351 is a brain penetrant MMP inhibitor with IC₅₀s of 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13, respectively^[1].

IC₅₀ & Target

MMP-9

11 nM (IC₅₀)

MMP-2

4 nM (IC₅₀)

MMP-8

2 nM (IC₅₀)

MMP13

50 nM (IC₅₀)

Ver todos los productos específicos de isoformas MMP :

Chemical Information

No. CAS 960113-85-3
Peso molecular 424.49
Fòrmula C₂₀H₂₅FN₂O₅S
SMILES

CC(C)[C@@H](N(S(=O)(C1=CC=C(OCCF)C=C1)=O)CC2=CC=CC=C2)C(NO)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Wagner S, et al. Novel fluorinated derivatives of the broad-spectrum MMP inhibitors N-hydroxy-2(R)-[[(4-methoxyphenyl)sulfonyl](benzyl)- and (3-picolyl)-amino]-3-methyl-butanamide as potential tools for the molecular imaging of activated MMPs with PET. J [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

Minimum order quantity

100 mg

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Actividad biológica
- Descripciòn
- IC₅₀ & Target
Chemical Information
Pureza y Documentación
Referencias

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BR351

Ver todos los productos específicos de isoformas MMP