BRCA1 - BRCA1 DNA repair associated Gene
Also Known as IRIS; PSCP; BRCAI; BRCC1; FANCS; PNCA4; RNF53; BROVCA1; PPP1R53
Species: Homo sapiens
About BRCA1
This gene has 41 transcripts (splice variants), 198 orthologues and is associated with 148 phenotypes. Broad expression in testis (RPKM 5.2), lymph node (RPKM 3.3) and 23 other tissues.
Summary
This gene encodes a 190 kD nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The BRCA1 gene contains 22 exons spanning about 110 kb of DNA. The encoded protein combines with Other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified. [provided by RefSeq, May 2020]
BRCA1 Products (368)
| mRNA | Protein | Name |
|---|---|---|
| NM_001407571.1 | NP_001394500.1 | breast cancer type 1 susceptibility protein isoform 6 |
| NM_001407581.1 | NP_001394510.1 | breast cancer type 1 susceptibility protein isoform 7 |
| NM_001407582.1 | NP_001394511.1 | breast cancer type 1 susceptibility protein isoform 7 |
| NM_001407583.1 | NP_001394512.1 | breast cancer type 1 susceptibility protein isoform 2 |
| NM_001407585.1 | NP_001394514.1 | breast cancer type 1 susceptibility protein isoform 2 |
| NM_001407587.1 | NP_001394516.1 | breast cancer type 1 susceptibility protein isoform 8 |
| NM_001407590.1 | NP_001394519.1 | breast cancer type 1 susceptibility protein isoform 9 |
| NM_001407591.1 | NP_001394520.1 | breast cancer type 1 susceptibility protein isoform 9 |
| NM_001407593.1 | NP_001394522.1 | breast cancer type 1 susceptibility protein isoform 1 |
| NM_001407594.1 | NP_001394523.1 | breast cancer type 1 susceptibility protein isoform 1 |
| NM_001407596.1 | NP_001394525.1 | breast cancer type 1 susceptibility protein isoform 1 |
| NM_001407597.1 | NP_001394526.1 | breast cancer type 1 susceptibility protein isoform 1 |
| NM_001407598.1 | NP_001394527.1 | breast cancer type 1 susceptibility protein isoform 1 |
| NM_001407602.1 | NP_001394531.1 | breast cancer type 1 susceptibility protein isoform 1 |
| NM_001407603.1 | NP_001394532.1 | breast cancer type 1 susceptibility protein isoform 1 |
| NM_001407605.1 | NP_001394534.1 | breast cancer type 1 susceptibility protein isoform 1 |
| NM_001407610.1 | NP_001394539.1 | breast cancer type 1 susceptibility protein isoform 10 |
| NM_001407611.1 | NP_001394540.1 | breast cancer type 1 susceptibility protein isoform 10 |
| NM_001407612.1 | NP_001394541.1 | breast cancer type 1 susceptibility protein isoform 10 |
| NM_001407613.1 | NP_001394542.1 | breast cancer type 1 susceptibility protein isoform 10 |
| NM_001407614.1 | NP_001394543.1 | breast cancer type 1 susceptibility protein isoform 10 |
| NM_001407615.1 | NP_001394544.1 | breast cancer type 1 susceptibility protein isoform 10 |
| NM_001407616.1 | NP_001394545.1 | breast cancer type 1 susceptibility protein isoform 11 |
| NM_001407617.1 | NP_001394546.1 | breast cancer type 1 susceptibility protein isoform 11 |
| NM_001407618.1 | NP_001394547.1 | breast cancer type 1 susceptibility protein isoform 11 |
| NM_001407619.1 | NP_001394548.1 | breast cancer type 1 susceptibility protein isoform 11 |
| NM_001407620.1 | NP_001394549.1 | breast cancer type 1 susceptibility protein isoform 11 |
| NM_001407621.1 | NP_001394550.1 | breast cancer type 1 susceptibility protein isoform 11 |
| NM_001407622.1 | NP_001394551.1 | breast cancer type 1 susceptibility protein isoform 11 |
| NM_001407623.1 | NP_001394552.1 | breast cancer type 1 susceptibility protein isoform 11 |
| NM_001407624.1 | NP_001394553.1 | breast cancer type 1 susceptibility protein isoform 12 |
| NM_001407625.1 | NP_001394554.1 | breast cancer type 1 susceptibility protein isoform 12 |
| NM_001407626.1 | NP_001394555.1 | breast cancer type 1 susceptibility protein isoform 12 |
| NM_001407627.1 | NP_001394556.1 | breast cancer type 1 susceptibility protein isoform 13 |
| NM_001407628.1 | NP_001394557.1 | breast cancer type 1 susceptibility protein isoform 13 |
| NM_001407629.1 | NP_001394558.1 | breast cancer type 1 susceptibility protein isoform 13 |
| NM_001407630.1 | NP_001394559.1 | breast cancer type 1 susceptibility protein isoform 13 |
| NM_001407631.1 | NP_001394560.1 | breast cancer type 1 susceptibility protein isoform 13 |
| NM_001407632.1 | NP_001394561.1 | breast cancer type 1 susceptibility protein isoform 13 |
| NM_001407633.1 | NP_001394562.1 | breast cancer type 1 susceptibility protein isoform 14 |
| NM_001407634.1 | NP_001394563.1 | breast cancer type 1 susceptibility protein isoform 14 |
| NM_001407635.1 | NP_001394564.1 | breast cancer type 1 susceptibility protein isoform 14 |
| NM_001407636.1 | NP_001394565.1 | breast cancer type 1 susceptibility protein isoform 14 |
| NM_001407637.1 | NP_001394566.1 | breast cancer type 1 susceptibility protein isoform 14 |
| NM_001407638.1 | NP_001394567.1 | breast cancer type 1 susceptibility protein isoform 14 |
| NM_001407639.1 | NP_001394568.1 | breast cancer type 1 susceptibility protein isoform 15 |
| NM_001407640.1 | NP_001394569.1 | breast cancer type 1 susceptibility protein isoform 15 |
| NM_001407641.1 | NP_001394570.1 | breast cancer type 1 susceptibility protein isoform 15 |
| NM_001407642.1 | NP_001394571.1 | breast cancer type 1 susceptibility protein isoform 15 |
| NM_001407644.1 | NP_001394573.1 | breast cancer type 1 susceptibility protein isoform 16 |
| NM_001407645.1 | NP_001394574.1 | breast cancer type 1 susceptibility protein isoform 16 |
| NM_001407646.1 | NP_001394575.1 | breast cancer type 1 susceptibility protein isoform 17 |
| NM_001407647.1 | NP_001394576.1 | breast cancer type 1 susceptibility protein isoform 18 |
| NM_001407648.1 | NP_001394577.1 | breast cancer type 1 susceptibility protein isoform 19 |
| NM_001407649.1 | NP_001394578.1 | breast cancer type 1 susceptibility protein isoform 20 |
| NM_001407652.1 | NP_001394581.1 | breast cancer type 1 susceptibility protein isoform 21 |
| NM_001407653.1 | NP_001394582.1 | breast cancer type 1 susceptibility protein isoform 22 |
| NM_001407654.1 | NP_001394583.1 | breast cancer type 1 susceptibility protein isoform 22 |
| NM_001407655.1 | NP_001394584.1 | breast cancer type 1 susceptibility protein isoform 22 |
| NM_001407656.1 | NP_001394585.1 | breast cancer type 1 susceptibility protein isoform 23 |
| NM_001407657.1 | NP_001394586.1 | breast cancer type 1 susceptibility protein isoform 24 |
| NM_001407658.1 | NP_001394587.1 | breast cancer type 1 susceptibility protein isoform 24 |
| NM_001407659.1 | NP_001394588.1 | breast cancer type 1 susceptibility protein isoform 25 |
| NM_001407660.1 | NP_001394589.1 | breast cancer type 1 susceptibility protein isoform 25 |
| NM_001407661.1 | NP_001394590.1 | breast cancer type 1 susceptibility protein isoform 26 |
| NM_001407662.1 | NP_001394591.1 | breast cancer type 1 susceptibility protein isoform 26 |
| NM_001407663.1 | NP_001394592.1 | breast cancer type 1 susceptibility protein isoform 93 |
| NM_001407664.1 | NP_001394593.1 | breast cancer type 1 susceptibility protein isoform 27 |
| NM_001407665.1 | NP_001394594.1 | breast cancer type 1 susceptibility protein isoform 27 |
| NM_001407666.1 | NP_001394595.1 | breast cancer type 1 susceptibility protein isoform 27 |
| NM_001407667.1 | NP_001394596.1 | breast cancer type 1 susceptibility protein isoform 27 |
| NM_001407668.1 | NP_001394597.1 | breast cancer type 1 susceptibility protein isoform 27 |
| NM_001407669.1 | NP_001394598.1 | breast cancer type 1 susceptibility protein isoform 27 |
| NM_001407670.1 | NP_001394599.1 | breast cancer type 1 susceptibility protein isoform 28 |
| NM_001407671.1 | NP_001394600.1 | breast cancer type 1 susceptibility protein isoform 28 |
| NM_001407672.1 | NP_001394601.1 | breast cancer type 1 susceptibility protein isoform 28 |
| NM_001407673.1 | NP_001394602.1 | breast cancer type 1 susceptibility protein isoform 28 |
| NM_001407674.1 | NP_001394603.1 | breast cancer type 1 susceptibility protein isoform 29 |
| NM_001407675.1 | NP_001394604.1 | breast cancer type 1 susceptibility protein isoform 29 |
| NM_001407676.1 | NP_001394605.1 | breast cancer type 1 susceptibility protein isoform 29 |
| NM_001407677.1 | NP_001394606.1 | breast cancer type 1 susceptibility protein isoform 30 |
| NM_001407678.1 | NP_001394607.1 | breast cancer type 1 susceptibility protein isoform 30 |
| NM_001407679.1 | NP_001394608.1 | breast cancer type 1 susceptibility protein isoform 30 |
| NM_001407680.1 | NP_001394609.1 | breast cancer type 1 susceptibility protein isoform 30 |
| NM_001407681.1 | NP_001394610.1 | breast cancer type 1 susceptibility protein isoform 31 |
| NM_001407682.1 | NP_001394611.1 | breast cancer type 1 susceptibility protein isoform 31 |
| NM_001407683.1 | NP_001394612.1 | breast cancer type 1 susceptibility protein isoform 31 |
| NM_001407684.1 | NP_001394613.1 | breast cancer type 1 susceptibility protein isoform 32 |
| NM_001407685.1 | NP_001394614.1 | breast cancer type 1 susceptibility protein isoform 33 |
| NM_001407686.1 | NP_001394615.1 | breast cancer type 1 susceptibility protein isoform 33 |
| NM_001407687.1 | NP_001394616.1 | breast cancer type 1 susceptibility protein isoform 33 |
| NM_001407688.1 | NP_001394617.1 | breast cancer type 1 susceptibility protein isoform 34 |
| NM_001407689.1 | NP_001394618.1 | breast cancer type 1 susceptibility protein isoform 34 |
| NM_001407690.1 | NP_001394619.1 | breast cancer type 1 susceptibility protein isoform 35 |
| NM_001407691.1 | NP_001394620.1 | breast cancer type 1 susceptibility protein isoform 35 |
| NM_001407692.1 | NP_001394621.1 | breast cancer type 1 susceptibility protein isoform 3 |
| NM_001407694.1 | NP_001394623.1 | breast cancer type 1 susceptibility protein isoform 3 |
| NM_001407695.1 | NP_001394624.1 | breast cancer type 1 susceptibility protein isoform 3 |
| NM_001407696.1 | NP_001394625.1 | breast cancer type 1 susceptibility protein isoform 3 |
| NM_001407697.1 | NP_001394626.1 | breast cancer type 1 susceptibility protein isoform 3 |
| NM_001407698.1 | NP_001394627.1 | breast cancer type 1 susceptibility protein isoform 3 |
| NM_001407724.1 | NP_001394653.1 | breast cancer type 1 susceptibility protein isoform 3 |
| NM_001407725.1 | NP_001394654.1 | breast cancer type 1 susceptibility protein isoform 3 |
| NM_001407726.1 | NP_001394655.1 | breast cancer type 1 susceptibility protein isoform 3 |
| NM_001407727.1 | NP_001394656.1 | breast cancer type 1 susceptibility protein isoform 3 |
| NM_001407728.1 | NP_001394657.1 | breast cancer type 1 susceptibility protein isoform 3 |
| NM_001407729.1 | NP_001394658.1 | breast cancer type 1 susceptibility protein isoform 3 |
| NM_001407730.1 | NP_001394659.1 | breast cancer type 1 susceptibility protein isoform 3 |
| NM_001407731.1 | NP_001394660.1 | breast cancer type 1 susceptibility protein isoform 3 |
| NM_001407732.1 | NP_001394661.1 | breast cancer type 1 susceptibility protein isoform 36 |
| NM_001407733.1 | NP_001394662.1 | breast cancer type 1 susceptibility protein isoform 36 |
| NM_001407734.1 | NP_001394663.1 | breast cancer type 1 susceptibility protein isoform 36 |
| NM_001407735.1 | NP_001394664.1 | breast cancer type 1 susceptibility protein isoform 36 |
| NM_001407736.1 | NP_001394665.1 | breast cancer type 1 susceptibility protein isoform 36 |
| NM_001407737.1 | NP_001394666.1 | breast cancer type 1 susceptibility protein isoform 36 |
| NM_001407738.1 | NP_001394667.1 | breast cancer type 1 susceptibility protein isoform 36 |
| NM_001407739.1 | NP_001394668.1 | breast cancer type 1 susceptibility protein isoform 36 |
| NM_001407740.1 | NP_001394669.1 | breast cancer type 1 susceptibility protein isoform 37 |
| NM_001407741.1 | NP_001394670.1 | breast cancer type 1 susceptibility protein isoform 37 |
| NM_001407742.1 | NP_001394671.1 | breast cancer type 1 susceptibility protein isoform 37 |
| NM_001407743.1 | NP_001394672.1 | breast cancer type 1 susceptibility protein isoform 37 |
| NM_001407744.1 | NP_001394673.1 | breast cancer type 1 susceptibility protein isoform 37 |
| NM_001407745.1 | NP_001394674.1 | breast cancer type 1 susceptibility protein isoform 37 |
| NM_001407746.1 | NP_001394675.1 | breast cancer type 1 susceptibility protein isoform 37 |
| NM_001407747.1 | NP_001394676.1 | breast cancer type 1 susceptibility protein isoform 37 |
| NM_001407748.1 | NP_001394677.1 | breast cancer type 1 susceptibility protein isoform 37 |
| NM_001407749.1 | NP_001394678.1 | breast cancer type 1 susceptibility protein isoform 37 |
| NM_001407750.1 | NP_001394679.1 | breast cancer type 1 susceptibility protein isoform 38 |
| NM_001407751.1 | NP_001394680.1 | breast cancer type 1 susceptibility protein isoform 38 |
| NM_001407752.1 | NP_001394681.1 | breast cancer type 1 susceptibility protein isoform 38 |
| NM_001407838.1 | NP_001394767.1 | breast cancer type 1 susceptibility protein isoform 39 |
| NM_001407839.1 | NP_001394768.1 | breast cancer type 1 susceptibility protein isoform 39 |
| NM_001407841.1 | NP_001394770.1 | breast cancer type 1 susceptibility protein isoform 39 |
| NM_001407842.1 | NP_001394771.1 | breast cancer type 1 susceptibility protein isoform 39 |
| NM_001407843.1 | NP_001394772.1 | breast cancer type 1 susceptibility protein isoform 39 |
| NM_001407844.1 | NP_001394773.1 | breast cancer type 1 susceptibility protein isoform 39 |
| NM_001407845.1 | NP_001394774.1 | breast cancer type 1 susceptibility protein isoform 39 |
| NM_001407846.1 | NP_001394775.1 | breast cancer type 1 susceptibility protein isoform 39 |
| NM_001407847.1 | NP_001394776.1 | breast cancer type 1 susceptibility protein isoform 40 |
| NM_001407848.1 | NP_001394777.1 | breast cancer type 1 susceptibility protein isoform 40 |
| NM_001407849.1 | NP_001394778.1 | breast cancer type 1 susceptibility protein isoform 40 |
| NM_001407850.1 | NP_001394779.1 | breast cancer type 1 susceptibility protein isoform 41 |
| NM_001407851.1 | NP_001394780.1 | breast cancer type 1 susceptibility protein isoform 41 |
| NM_001407852.1 | NP_001394781.1 | breast cancer type 1 susceptibility protein isoform 41 |
| NM_001407853.1 | NP_001394782.1 | breast cancer type 1 susceptibility protein isoform 42 |
| NM_001407854.1 | NP_001394783.1 | breast cancer type 1 susceptibility protein isoform 43 |
| NM_001407858.1 | NP_001394787.1 | breast cancer type 1 susceptibility protein isoform 44 |
| NM_001407859.1 | NP_001394788.1 | breast cancer type 1 susceptibility protein isoform 44 |
| NM_001407860.1 | NP_001394789.1 | breast cancer type 1 susceptibility protein isoform 45 |
| NM_001407861.1 | NP_001394790.1 | breast cancer type 1 susceptibility protein isoform 46 |
| NM_001407862.1 | NP_001394791.1 | breast cancer type 1 susceptibility protein isoform 47 |
| NM_001407863.1 | NP_001394792.1 | breast cancer type 1 susceptibility protein isoform 48 |
| NM_001407874.1 | NP_001394803.1 | breast cancer type 1 susceptibility protein isoform 49 |
| NM_001407875.1 | NP_001394804.1 | breast cancer type 1 susceptibility protein isoform 49 |
| NM_001407879.1 | NP_001394808.1 | breast cancer type 1 susceptibility protein isoform 50 |
| NM_001407881.1 | NP_001394810.1 | breast cancer type 1 susceptibility protein isoform 50 |
| NM_001407882.1 | NP_001394811.1 | breast cancer type 1 susceptibility protein isoform 50 |
| NM_001407884.1 | NP_001394813.1 | breast cancer type 1 susceptibility protein isoform 50 |
| NM_001407885.1 | NP_001394814.1 | breast cancer type 1 susceptibility protein isoform 50 |
| NM_001407886.1 | NP_001394815.1 | breast cancer type 1 susceptibility protein isoform 50 |
| NM_001407887.1 | NP_001394816.1 | breast cancer type 1 susceptibility protein isoform 50 |
| NM_001407889.1 | NP_001394818.1 | breast cancer type 1 susceptibility protein isoform 50 |
| NM_001407894.1 | NP_001394823.1 | breast cancer type 1 susceptibility protein isoform 6 |
| NM_001407895.1 | NP_001394824.1 | breast cancer type 1 susceptibility protein isoform 6 |
| NM_001407896.1 | NP_001394825.1 | breast cancer type 1 susceptibility protein isoform 6 |
| NM_001407897.1 | NP_001394826.1 | breast cancer type 1 susceptibility protein isoform 6 |
| NM_001407898.1 | NP_001394827.1 | breast cancer type 1 susceptibility protein isoform 6 |
| NM_001407899.1 | NP_001394828.1 | breast cancer type 1 susceptibility protein isoform 6 |
| NM_001407900.1 | NP_001394829.1 | breast cancer type 1 susceptibility protein isoform 52 |
| NM_001407902.1 | NP_001394831.1 | breast cancer type 1 susceptibility protein isoform 52 |
| NM_001407904.1 | NP_001394833.1 | breast cancer type 1 susceptibility protein isoform 52 |
| NM_001407906.1 | NP_001394835.1 | breast cancer type 1 susceptibility protein isoform 52 |
| NM_001407907.1 | NP_001394836.1 | breast cancer type 1 susceptibility protein isoform 53 |
| NM_001407908.1 | NP_001394837.1 | breast cancer type 1 susceptibility protein isoform 53 |
| NM_001407909.1 | NP_001394838.1 | breast cancer type 1 susceptibility protein isoform 53 |
| NM_001407910.1 | NP_001394839.1 | breast cancer type 1 susceptibility protein isoform 53 |
| NM_001407915.1 | NP_001394844.1 | breast cancer type 1 susceptibility protein isoform 54 |
| NM_001407916.1 | NP_001394845.1 | breast cancer type 1 susceptibility protein isoform 55 |
| NM_001407917.1 | NP_001394846.1 | breast cancer type 1 susceptibility protein isoform 55 |
| NM_001407918.1 | NP_001394847.1 | breast cancer type 1 susceptibility protein isoform 55 |
| NM_001407919.1 | NP_001394848.1 | breast cancer type 1 susceptibility protein isoform 56 |
| NM_001407920.1 | NP_001394849.1 | breast cancer type 1 susceptibility protein isoform 57 |
| NM_001407921.1 | NP_001394850.1 | breast cancer type 1 susceptibility protein isoform 57 |
| NM_001407922.1 | NP_001394851.1 | breast cancer type 1 susceptibility protein isoform 57 |
| NM_001407923.1 | NP_001394852.1 | breast cancer type 1 susceptibility protein isoform 57 |
| NM_001407924.1 | NP_001394853.1 | breast cancer type 1 susceptibility protein isoform 57 |
| NM_001407925.1 | NP_001394854.1 | breast cancer type 1 susceptibility protein isoform 57 |
| NM_001407926.1 | NP_001394855.1 | breast cancer type 1 susceptibility protein isoform 57 |
| NM_001407927.1 | NP_001394856.1 | breast cancer type 1 susceptibility protein isoform 58 |
| NM_001407928.1 | NP_001394857.1 | breast cancer type 1 susceptibility protein isoform 58 |
| NM_001407929.1 | NP_001394858.1 | breast cancer type 1 susceptibility protein isoform 58 |
| NM_001407930.1 | NP_001394859.1 | breast cancer type 1 susceptibility protein isoform 59 |
| NM_001407931.1 | NP_001394860.1 | breast cancer type 1 susceptibility protein isoform 59 |
| NM_001407932.1 | NP_001394861.1 | breast cancer type 1 susceptibility protein isoform 59 |
| NM_001407933.1 | NP_001394862.1 | breast cancer type 1 susceptibility protein isoform 60 |
| NM_001407934.1 | NP_001394863.1 | breast cancer type 1 susceptibility protein isoform 61 |
| NM_001407935.1 | NP_001394864.1 | breast cancer type 1 susceptibility protein isoform 62 |
| NM_001407936.1 | NP_001394865.1 | breast cancer type 1 susceptibility protein isoform 63 |
| NM_001407937.1 | NP_001394866.1 | breast cancer type 1 susceptibility protein isoform 64 |
| NM_001407938.1 | NP_001394867.1 | breast cancer type 1 susceptibility protein isoform 64 |
| NM_001407939.1 | NP_001394868.1 | breast cancer type 1 susceptibility protein isoform 65 |
| NM_001407940.1 | NP_001394869.1 | breast cancer type 1 susceptibility protein isoform 66 |
| NM_001407941.1 | NP_001394870.1 | breast cancer type 1 susceptibility protein isoform 67 |
| NM_001407942.1 | NP_001394871.1 | breast cancer type 1 susceptibility protein isoform 68 |
| NM_001407943.1 | NP_001394872.1 | breast cancer type 1 susceptibility protein isoform 69 |
| NM_001407944.1 | NP_001394873.1 | breast cancer type 1 susceptibility protein isoform 70 |
| NM_001407945.1 | NP_001394874.1 | breast cancer type 1 susceptibility protein isoform 70 |
| NM_001407946.1 | NP_001394875.1 | breast cancer type 1 susceptibility protein isoform 71 |
| NM_001407947.1 | NP_001394876.1 | breast cancer type 1 susceptibility protein isoform 71 |
| NM_001407948.1 | NP_001394877.1 | breast cancer type 1 susceptibility protein isoform 71 |
| NM_001407949.1 | NP_001394878.1 | breast cancer type 1 susceptibility protein isoform 71 |
| NM_001407950.1 | NP_001394879.1 | breast cancer type 1 susceptibility protein isoform 72 |
| NM_001407951.1 | NP_001394880.1 | breast cancer type 1 susceptibility protein isoform 72 |
| NM_001407952.1 | NP_001394881.1 | breast cancer type 1 susceptibility protein isoform 73 |
| NM_001407953.1 | NP_001394882.1 | breast cancer type 1 susceptibility protein isoform 73 |
| NM_001407954.1 | NP_001394883.1 | breast cancer type 1 susceptibility protein isoform 74 |
| NM_001407955.1 | NP_001394884.1 | breast cancer type 1 susceptibility protein isoform 74 |
| NM_001407956.1 | NP_001394885.1 | breast cancer type 1 susceptibility protein isoform 75 |
| NM_001407957.1 | NP_001394886.1 | breast cancer type 1 susceptibility protein isoform 76 |
| NM_001407958.1 | NP_001394887.1 | breast cancer type 1 susceptibility protein isoform 77 |
| NM_001407959.1 | NP_001394888.1 | breast cancer type 1 susceptibility protein isoform 78 |
| NM_001407960.1 | NP_001394889.1 | breast cancer type 1 susceptibility protein isoform 79 |
| NM_001407962.1 | NP_001394891.1 | breast cancer type 1 susceptibility protein isoform 80 |
| NM_001407963.1 | NP_001394892.1 | breast cancer type 1 susceptibility protein isoform 81 |
| NM_001407964.1 | NP_001394893.1 | breast cancer type 1 susceptibility protein isoform 82 |
| NM_001407965.1 | NP_001394894.1 | breast cancer type 1 susceptibility protein isoform 83 |
| NM_001407966.1 | NP_001394895.1 | breast cancer type 1 susceptibility protein isoform 84 |
| NM_001407967.1 | NP_001394896.1 | breast cancer type 1 susceptibility protein isoform 85 |
| NM_001407968.1 | NP_001394897.1 | breast cancer type 1 susceptibility protein isoform 86 |
| NM_001407969.1 | NP_001394898.1 | breast cancer type 1 susceptibility protein isoform 87 |
| NM_001407970.1 | NP_001394899.1 | breast cancer type 1 susceptibility protein isoform 88 |
| NM_001407971.1 | NP_001394900.1 | breast cancer type 1 susceptibility protein isoform 88 |
| NM_001407972.1 | NP_001394901.1 | breast cancer type 1 susceptibility protein isoform 89 |
| NM_001407973.1 | NP_001394902.1 | breast cancer type 1 susceptibility protein isoform 90 |
| NM_001407974.1 | NP_001394903.1 | breast cancer type 1 susceptibility protein isoform 90 |
| NM_001407975.1 | NP_001394904.1 | breast cancer type 1 susceptibility protein isoform 90 |
| NM_001407976.1 | NP_001394905.1 | breast cancer type 1 susceptibility protein isoform 90 |
| NM_001407977.1 | NP_001394906.1 | breast cancer type 1 susceptibility protein isoform 90 |
| NM_001407978.1 | NP_001394907.1 | breast cancer type 1 susceptibility protein isoform 90 |
| NM_001407979.1 | NP_001394908.1 | breast cancer type 1 susceptibility protein isoform 91 |
| NM_001407980.1 | NP_001394909.1 | breast cancer type 1 susceptibility protein isoform 91 |
| NM_001407981.1 | NP_001394910.1 | breast cancer type 1 susceptibility protein isoform 91 |
| NM_001407982.1 | NP_001394911.1 | breast cancer type 1 susceptibility protein isoform 91 |
| NM_001407983.1 | NP_001394912.1 | breast cancer type 1 susceptibility protein isoform 91 |
| NM_001407984.1 | NP_001394913.1 | breast cancer type 1 susceptibility protein isoform 92 |
| NM_001407985.1 | NP_001394914.1 | breast cancer type 1 susceptibility protein isoform 92 |
| NM_001407986.1 | NP_001394915.1 | breast cancer type 1 susceptibility protein isoform 92 |
| NM_001407990.1 | NP_001394919.1 | breast cancer type 1 susceptibility protein isoform 91 |
| NM_001407991.1 | NP_001394920.1 | breast cancer type 1 susceptibility protein isoform 92 |
| NM_001407992.1 | NP_001394921.1 | breast cancer type 1 susceptibility protein isoform 92 |
| NM_001407993.1 | NP_001394922.1 | breast cancer type 1 susceptibility protein isoform 4 |
| NM_001408392.1 | NP_001395321.1 | breast cancer type 1 susceptibility protein isoform 94 |
| NM_001408396.1 | NP_001395325.1 | breast cancer type 1 susceptibility protein isoform 94 |
| NM_001408397.1 | NP_001395326.1 | breast cancer type 1 susceptibility protein isoform 94 |
| NM_001408398.1 | NP_001395327.1 | breast cancer type 1 susceptibility protein isoform 94 |
| NM_001408399.1 | NP_001395328.1 | breast cancer type 1 susceptibility protein isoform 94 |
| NM_001408400.1 | NP_001395329.1 | breast cancer type 1 susceptibility protein isoform 95 |
| NM_001408401.1 | NP_001395330.1 | breast cancer type 1 susceptibility protein isoform 95 |
| NM_001408402.1 | NP_001395331.1 | breast cancer type 1 susceptibility protein isoform 95 |
| NM_001408403.1 | NP_001395332.1 | breast cancer type 1 susceptibility protein isoform 96 |
| NM_001408404.1 | NP_001395333.1 | breast cancer type 1 susceptibility protein isoform 96 |
| NM_001408406.1 | NP_001395335.1 | breast cancer type 1 susceptibility protein isoform 97 |
| NM_001408407.1 | NP_001395336.1 | breast cancer type 1 susceptibility protein isoform 98 |
| NM_001408408.1 | NP_001395337.1 | breast cancer type 1 susceptibility protein isoform 99 |
| NM_001408409.1 | NP_001395338.1 | breast cancer type 1 susceptibility protein isoform 100 |
| NM_001408410.1 | NP_001395339.1 | breast cancer type 1 susceptibility protein isoform 101 |
| NM_001408411.1 | NP_001395340.1 | breast cancer type 1 susceptibility protein isoform 102 |
| NM_001408412.1 | NP_001395341.1 | breast cancer type 1 susceptibility protein isoform 103 |
| NM_001408413.1 | NP_001395342.1 | breast cancer type 1 susceptibility protein isoform 104 |
| NM_001408414.1 | NP_001395343.1 | breast cancer type 1 susceptibility protein isoform 103 |
| NM_001408415.1 | NP_001395344.1 | breast cancer type 1 susceptibility protein isoform 103 |
| NM_001408416.1 | NP_001395345.1 | breast cancer type 1 susceptibility protein isoform 104 |
| NM_001408418.1 | NP_001395347.1 | breast cancer type 1 susceptibility protein isoform 105 |
| NM_001408419.1 | NP_001395348.1 | breast cancer type 1 susceptibility protein isoform 105 |
| NM_001408420.1 | NP_001395349.1 | breast cancer type 1 susceptibility protein isoform 105 |
| NM_001408421.1 | NP_001395350.1 | breast cancer type 1 susceptibility protein isoform 106 |
| NM_001408422.1 | NP_001395351.1 | breast cancer type 1 susceptibility protein isoform 107 |
| NM_001408423.1 | NP_001395352.1 | breast cancer type 1 susceptibility protein isoform 107 |
| NM_001408424.1 | NP_001395353.1 | breast cancer type 1 susceptibility protein isoform 106 |
| NM_001408425.1 | NP_001395354.1 | breast cancer type 1 susceptibility protein isoform 108 |
| NM_001408426.1 | NP_001395355.1 | breast cancer type 1 susceptibility protein isoform 108 |
| NM_001408427.1 | NP_001395356.1 | breast cancer type 1 susceptibility protein isoform 108 |
| NM_001408428.1 | NP_001395357.1 | breast cancer type 1 susceptibility protein isoform 108 |
| NM_001408429.1 | NP_001395358.1 | breast cancer type 1 susceptibility protein isoform 108 |
| NM_001408430.1 | NP_001395359.1 | breast cancer type 1 susceptibility protein isoform 108 |
| NM_001408431.1 | NP_001395360.1 | breast cancer type 1 susceptibility protein isoform 109 |
| NM_001408432.1 | NP_001395361.1 | breast cancer type 1 susceptibility protein isoform 110 |
| NM_001408433.1 | NP_001395362.1 | breast cancer type 1 susceptibility protein isoform 110 |
| NM_001408434.1 | NP_001395363.1 | breast cancer type 1 susceptibility protein isoform 110 |
| NM_001408435.1 | NP_001395364.1 | breast cancer type 1 susceptibility protein isoform 110 |
| NM_001408436.1 | NP_001395365.1 | breast cancer type 1 susceptibility protein isoform 111 |
| NM_001408437.1 | NP_001395366.1 | breast cancer type 1 susceptibility protein isoform 111 |
| NM_001408438.1 | NP_001395367.1 | breast cancer type 1 susceptibility protein isoform 111 |
| NM_001408439.1 | NP_001395368.1 | breast cancer type 1 susceptibility protein isoform 111 |
| NM_001408440.1 | NP_001395369.1 | breast cancer type 1 susceptibility protein isoform 111 |
| NM_001408441.1 | NP_001395370.1 | breast cancer type 1 susceptibility protein isoform 112 |
| NM_001408442.1 | NP_001395371.1 | breast cancer type 1 susceptibility protein isoform 112 |
| NM_001408443.1 | NP_001395372.1 | breast cancer type 1 susceptibility protein isoform 112 |
| NM_001408444.1 | NP_001395373.1 | breast cancer type 1 susceptibility protein isoform 112 |
| NM_001408445.1 | NP_001395374.1 | breast cancer type 1 susceptibility protein isoform 113 |
| NM_001408446.1 | NP_001395375.1 | breast cancer type 1 susceptibility protein isoform 113 |
| NM_001408447.1 | NP_001395376.1 | breast cancer type 1 susceptibility protein isoform 113 |
| NM_001408448.1 | NP_001395377.1 | breast cancer type 1 susceptibility protein isoform 113 |
| NM_001408450.1 | NP_001395379.1 | breast cancer type 1 susceptibility protein isoform 113 |
| NM_001408451.1 | NP_001395380.1 | breast cancer type 1 susceptibility protein isoform 114 |
| NM_001408452.1 | NP_001395381.1 | breast cancer type 1 susceptibility protein isoform 115 |
| NM_001408453.1 | NP_001395382.1 | breast cancer type 1 susceptibility protein isoform 115 |
| NM_001408454.1 | NP_001395383.1 | breast cancer type 1 susceptibility protein isoform 115 |
| NM_001408455.1 | NP_001395384.1 | breast cancer type 1 susceptibility protein isoform 115 |
| NM_001408456.1 | NP_001395385.1 | breast cancer type 1 susceptibility protein isoform 115 |
| NM_001408457.1 | NP_001395386.1 | breast cancer type 1 susceptibility protein isoform 115 |
| NM_001408458.1 | NP_001395387.1 | breast cancer type 1 susceptibility protein isoform 116 |
| NM_001408459.1 | NP_001395388.1 | breast cancer type 1 susceptibility protein isoform 116 |
| NM_001408460.1 | NP_001395389.1 | breast cancer type 1 susceptibility protein isoform 116 |
| NM_001408461.1 | NP_001395390.1 | breast cancer type 1 susceptibility protein isoform 116 |
| NM_001408462.1 | NP_001395391.1 | breast cancer type 1 susceptibility protein isoform 117 |
| NM_001408463.1 | NP_001395392.1 | breast cancer type 1 susceptibility protein isoform 117 |
| NM_001408464.1 | NP_001395393.1 | breast cancer type 1 susceptibility protein isoform 117 |
| NM_001408465.1 | NP_001395394.1 | breast cancer type 1 susceptibility protein isoform 117 |
| NM_001408466.1 | NP_001395395.1 | breast cancer type 1 susceptibility protein isoform 118 |
| NM_001408467.1 | NP_001395396.1 | breast cancer type 1 susceptibility protein isoform 118 |
| NM_001408468.1 | NP_001395397.1 | breast cancer type 1 susceptibility protein isoform 119 |
| NM_001408469.1 | NP_001395398.1 | breast cancer type 1 susceptibility protein isoform 120 |
| NM_001408470.1 | NP_001395399.1 | breast cancer type 1 susceptibility protein isoform 121 |
| NM_001408472.1 | NP_001395401.1 | breast cancer type 1 susceptibility protein isoform 122 |
| NM_001408473.1 | NP_001395402.1 | breast cancer type 1 susceptibility protein isoform 123 |
| NM_001408474.1 | NP_001395403.1 | breast cancer type 1 susceptibility protein isoform 124 |
| NM_001408475.1 | NP_001395404.1 | breast cancer type 1 susceptibility protein isoform 125 |
| NM_001408476.1 | NP_001395405.1 | breast cancer type 1 susceptibility protein isoform 126 |
| NM_001408478.1 | NP_001395407.1 | breast cancer type 1 susceptibility protein isoform 127 |
| NM_001408479.1 | NP_001395408.1 | breast cancer type 1 susceptibility protein isoform 127 |
| NM_001408480.1 | NP_001395409.1 | breast cancer type 1 susceptibility protein isoform 127 |
| NM_001408481.1 | NP_001395410.1 | breast cancer type 1 susceptibility protein isoform 128 |
| NM_001408482.1 | NP_001395411.1 | breast cancer type 1 susceptibility protein isoform 128 |
| NM_001408483.1 | NP_001395412.1 | breast cancer type 1 susceptibility protein isoform 128 |
| NM_001408484.1 | NP_001395413.1 | breast cancer type 1 susceptibility protein isoform 128 |
| NM_001408485.1 | NP_001395414.1 | breast cancer type 1 susceptibility protein isoform 128 |
| NM_001408489.1 | NP_001395418.1 | breast cancer type 1 susceptibility protein isoform 129 |
| NM_001408490.1 | NP_001395419.1 | breast cancer type 1 susceptibility protein isoform 130 |
| NM_001408491.1 | NP_001395420.1 | breast cancer type 1 susceptibility protein isoform 130 |
| NM_001408492.1 | NP_001395421.1 | breast cancer type 1 susceptibility protein isoform 131 |
| NM_001408493.1 | NP_001395422.1 | breast cancer type 1 susceptibility protein isoform 132 |
| NM_001408494.1 | NP_001395423.1 | breast cancer type 1 susceptibility protein isoform 133 |
| NM_001408495.1 | NP_001395424.1 | breast cancer type 1 susceptibility protein isoform 134 |
| NM_001408496.1 | NP_001395425.1 | breast cancer type 1 susceptibility protein isoform 135 |
| NM_001408497.1 | NP_001395426.1 | breast cancer type 1 susceptibility protein isoform 135 |
| NM_001408498.1 | NP_001395427.1 | breast cancer type 1 susceptibility protein isoform 135 |
| NM_001408499.1 | NP_001395428.1 | breast cancer type 1 susceptibility protein isoform 135 |
| NM_001408500.1 | NP_001395429.1 | breast cancer type 1 susceptibility protein isoform 135 |
| NM_001408501.1 | NP_001395430.1 | breast cancer type 1 susceptibility protein isoform 135 |
| NM_001408502.1 | NP_001395431.1 | breast cancer type 1 susceptibility protein isoform 136 |
| NM_001408503.1 | NP_001395432.1 | breast cancer type 1 susceptibility protein isoform 137 |
| NM_001408504.1 | NP_001395433.1 | breast cancer type 1 susceptibility protein isoform 137 |
| NM_001408505.1 | NP_001395434.1 | breast cancer type 1 susceptibility protein isoform 138 |
| NM_001408506.1 | NP_001395435.1 | breast cancer type 1 susceptibility protein isoform 139 |
| NM_001408507.1 | NP_001395436.1 | breast cancer type 1 susceptibility protein isoform 140 |
| NM_001408508.1 | NP_001395437.1 | breast cancer type 1 susceptibility protein isoform 141 |
| NM_001408509.1 | NP_001395438.1 | breast cancer type 1 susceptibility protein isoform 142 |
| NM_001408510.1 | NP_001395439.1 | breast cancer type 1 susceptibility protein isoform 143 |
| NM_001408511.1 | NP_001395440.1 | breast cancer type 1 susceptibility protein isoform 144 |
| NM_001408512.1 | NP_001395441.1 | breast cancer type 1 susceptibility protein isoform 145 |
| NM_001408513.1 | NP_001395442.1 | breast cancer type 1 susceptibility protein isoform 146 |
| NM_001408514.1 | NP_001395443.1 | breast cancer type 1 susceptibility protein isoform 147 |
| NM_007294.4 | NP_009225.1 | breast cancer type 1 susceptibility protein isoform 1 |
| NM_007297.4 | NP_009228.2 | breast cancer type 1 susceptibility protein isoform 3 |
| NM_007298.4 | NP_009229.2 | breast cancer type 1 susceptibility protein isoform 4 |
| NM_007299.4 | NP_009230.2 | breast cancer type 1 susceptibility protein isoform 5 |
| NM_007300.4 | NP_009231.2 | breast cancer type 1 susceptibility protein isoform 2 |
BRCA1 Protein Structure
zf-C3HC4: Zinc finger, C3HC4 type (RING finger) (24 - 64)
BRCT_assoc: Serine-rich domain associated with BRCT (344 - 507)
EIN3: Ethylene insensitive 3 (648 - 978)
BRCT: BRCA1 C Terminus (BRCT) domain (1662 - 1723)
BRCT: BRCA1 C Terminus (BRCT) domain (1757 - 1842)
- 0
- 300
- 600
- 900
- 1200
- 1500
- 1863 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
breast cancer type 1 susceptibility protein |
|
BRCA1 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | Referencias |
|---|---|---|---|---|---|---|---|
|
Intra
|
BRCA1 | P38398 | BRAT1 | Homo sapiens | Q6PJG6 | 16452482 | |
|
Intra
|
BRCA1 | P38398 | BRAT1 | Homo sapiens | Q6PJG6 | 16452482 | |
|
Intra
|
BRCA1 | P38398 | BRAT1 | Homo sapiens | Q6PJG6 | 16452482 | |
|
Intra
|
BRCA1 | P38398 | BRAT1 | Homo sapiens | Q6PJG6 | 16452482 | |
|
Intra
|
BRCA1 | P38398 | PALB2 | Homo sapiens | Q86YC2 | 19369211 | |
|
Intra
|
BRCA1 | P38398 | PALB2 | Homo sapiens | Q86YC2 | 19369211 | |
|
Intra
|
BRCA1 | P38398 | PALB2 | Homo sapiens | Q86YC2 | 28319063 | |
|
Intra
|
BRCA1 | P38398 | PALB2 | Homo sapiens | Q86YC2 | 22193777 | |
|
Intra
|
BRCA1 | P38398 | PALB2 | Homo sapiens | Q86YC2 | 29656893 | |
|
Intra
|
BRCA1 | P38398 | ZCCHC8 | Homo sapiens | Q6NZY4 | 17525332 | |
|
Intra
|
BRCA1 | P38398 | ABRAXAS1 | Homo sapiens | Q6UWZ7 | 34591612 | |
|
Intra
|
BRCA1 | P38398 | ABRAXAS1 | Homo sapiens | Q6UWZ7 | 17525340 | |
|
Intra
|
BRCA1 | P38398 | ABRAXAS1 | Homo sapiens | Q6UWZ7 | 17525340 | |
|
Intra
|
BRCA1 | P38398 | ABRAXAS1 | Homo sapiens | Q6UWZ7 | 17525340 | |
|
Intra
|
BRCA1 | P38398 | ABRAXAS1 | Homo sapiens | Q6UWZ7 | 29656893 | |
|
Intra
|
BRCA1 | P38398 | BAP1 | Homo sapiens | Q92560 | 9528852 | |
|
Intra
|
BRCA1 | P38398 | HMMR | Homo sapiens | O75330 | 22110403 | |
|
Intra
|
BRCA1 | P38398 | IFI16 | Homo sapiens | Q16666 | 14654789 | |
|
Intra
|
BRCA1 | P38398 | IFI16 | Homo sapiens | Q16666 | 14654789 | |
|
Intra
|
BRCA1 | P38398 | IFI16 | Homo sapiens | Q16666 | 14654789 | |
|
Intra
|
BRCA1 | P38398 | NELFB | Homo sapiens | Q8WX92 | 11739404 | |
|
Intra
|
BRCA1 | P38398 | NELFB | Homo sapiens | Q8WX92 | 11739404 | |
|
Intra
|
BRCA1 | P38398 | NELFB | Homo sapiens | Q8WX92 | 11739404 | |
|
Intra
|
BRCA1 | P38398 | BRAP | Homo sapiens | Q7Z569 | 9497340 | |
|
Intra
|
BRCA1 | P38398 | BRIP1 | Homo sapiens | Q9BX63 | 15133502 | |
|
Intra
|
BRCA1 | P38398 | BRIP1 | Homo sapiens | Q9BX63 | 34591612 | |
|
Intra
|
BRCA1 | P38398 | BRIP1 | Homo sapiens | Q9BX63 | 19369211 | |
|
Intra
|
BRCA1 | P38398 | BRIP1 | Homo sapiens | Q9BX63 | 17525340 | |
|
Intra
|
BRCA1 | P38398 | BRIP1 | Homo sapiens | Q9BX63 | 19369211 | |
|
Intra
|
BRCA1 | P38398 | BRIP1 | Homo sapiens | Q9BX63 | 21240188 | |
|
Intra
|
BRCA1 | P38398 | BRIP1 | Homo sapiens | Q9BX63 | 15125843 | |
|
Intra
|
BRCA1 | P38398 | BRIP1 | Homo sapiens | Q9BX63 | 15133502 | |
|
Intra
|
BRCA1 | P38398 | BRIP1 | Homo sapiens | Q9BX63 | 14576432 | |
|
Intra
|
BRCA1 | P38398 | BRIP1 | Homo sapiens | Q9BX63 | 14576432 | |
|
Intra
|
BRCA1 | P38398 | BRIP1 | Homo sapiens | Q9BX63 | 19369211 | |
|
Intra
|
BRCA1 | P38398 | BRIP1 | Homo sapiens | Q9BX63 | 29656893 | |
|
Intra
|
BRCA1 | P38398 | BRIP1 | Homo sapiens | Q9BX63 | 17581638 | |
|
Intra
|
BRCA1 | P38398 | BRIP1 | Homo sapiens | Q9BX63 | 22792074 | |
|
Intra
|
BRCA1 | P38398 | BRIP1 | Homo sapiens | Q9BX63 | 17525340 | |
|
Intra
|
BRCA1 | P38398 | BRIP1 | Homo sapiens | Q9BX63 | 18285836 | |
|
Intra
|
BRCA1 | P38398 | KPNA2 | Homo sapiens | P52292 | 9497340 | |
|
Intra
|
BRCA1 | P38398 | PPP1R9B | Homo sapiens | Q96SB3 | 34591612 | |
|
Intra
|
BRCA1 | P38398 | PPP1CB | Homo sapiens | P62140 | 17511879 | |
|
Intra
|
BRCA1 | P38398 | PPP1CB | Homo sapiens | P62140 | 17511879 | |
|
Intra
|
BRCA1 | P38398 | PPP1CB | Homo sapiens | P62140 | 17511879 | |
|
Intra
|
BRCA1 | P38398 | HSPD1 | Homo sapiens | P10809 | 21988832 | |
|
Intra
|
BRCA1 | P38398 | PPP1CC | Homo sapiens | P36873 | 17511879 | |
|
Intra
|
BRCA1 | P38398 | PPP1CC | Homo sapiens | P36873 | 17511879 | |
|
Intra
|
BRCA1 | P38398 | GTF2I | Homo sapiens | P78347 | 21407215 | |
|
Intra
|
BRCA1 | P38398 | GTF2I | Homo sapiens | P78347 | 21407215 | |
|
Intra
|
BRCA1 | P38398 | GTF2I | Homo sapiens | P78347 | 21407215 | |
|
Intra
|
BRCA1 | P38398 | ZNF350 | Homo sapiens | Q9GZX5 | 11090615 | |
|
Intra
|
BRCA1 | P38398 | TP53BP1 | Homo sapiens | Q12888 | 17525332 | |
|
Intra
|
BRCA1 | P38398 | TP53BP1 | Homo sapiens | Q12888 | 22884692 | |
|
Intra
|
BRCA1 | P38398 | TP53BP1 | Homo sapiens | Q12888 | 29656893 | |
|
Intra
|
BRCA1 | P38398 | BARD1 | Homo sapiens | Q99728 | 8944023 | |
|
Intra
|
BRCA1 | P38398 | BARD1 | Homo sapiens | Q99728 | 24981860 | |
|
Intra
|
BRCA1 | P38398 | BARD1 | Homo sapiens | Q99728 | 29656893 | |
|
Intra
|
BRCA1 | P38398 | BARD1 | Homo sapiens | Q99728 | 22110403 | |
|
Intra
|
BRCA1 | P38398 | BARD1 | Homo sapiens | Q99728 | 10477523 | |
|
Intra
|
BRCA1 | P38398 | BARD1 | Homo sapiens | Q99728 | 8944023 | |
|
Intra
|
BRCA1 | P38398 | BARD1 | Homo sapiens | Q99728 | 17873885 | |
|
Intra
|
BRCA1 | P38398 | BARD1 | Homo sapiens | Q99728 | 33961781 | |
|
Intra
|
BRCA1 | P38398 | BARD1 | Homo sapiens | Q99728 | 19369211 | |
|
Intra
|
BRCA1 | P38398 | BARD1 | Homo sapiens | Q99728 | 34591612 | |
|
Intra
|
BRCA1 | P38398 | BARD1 | Homo sapiens | Q99728 | 17873885 | |
|
Intra
|
BRCA1 | P38398 | BARD1 | Homo sapiens | Q99728 | 8944023 | |
|
Intra
|
BRCA1 | P38398 | BARD1 | Homo sapiens | Q99728 | 8944023 | |
|
Intra
|
BRCA1 | P38398 | BARD1 | Homo sapiens | Q99728 | 23680151 | |
|
Intra
|
BRCA1 | P38398 | SUMO2 | Homo sapiens | P61956 | 20016594 | |
|
Intra
|
BRCA1 | P38398 | SUMO2 | Homo sapiens | P61956 | 20016603 | |
|
Intra
|
BRCA1 | P38398 | H2AX | Homo sapiens | P16104 | 22193777 | |
|
Intra
|
BRCA1 | P38398 | H2AX | Homo sapiens | P16104 | 12419185 | |
|
Intra
|
BRCA1 | P38398 | MDC1 | Homo sapiens | Q14676 | 17525332 | |
|
Intra
|
BRCA1 | P38398 | MDC1 | Homo sapiens | Q14676 | 29656893 | |
|
Intra
|
BRCA1 | P38398 | MDC1 | Homo sapiens | Q14676 | 12607005 | |
|
Intra
|
BRCA1 | P38398 | CCNE1 | Homo sapiens | P24864 | 17525332 | |
|
Intra
|
BRCA1 | P38398 | TOP2A | Homo sapiens | P11388 | 15965487 | |
|
Intra
|
BRCA1 | P38398 | TOP2A | Homo sapiens | P11388 | 15965487 | |
|
Intra
|
BRCA1 | P38398 | FHL2 | Homo sapiens | Q14192 | 14550570 | |
|
Intra
|
BRCA1 | P38398 | FHL2 | Homo sapiens | Q14192 | 14550570 | |
|
Intra
|
BRCA1 | P38398 | FHL2 | Homo sapiens | Q14192 | 14550570 | |
|
Intra
|
BRCA1 | P38398 | ACACA | Homo sapiens | Q13085 | 16326698 | |
|
Intra
|
BRCA1 | P38398 | ACACA | Homo sapiens | Q13085 | 16326698 | |
|
Intra
|
BRCA1 | P38398 | UIMC1 | Homo sapiens | Q96RL1 | 34591612 | |
|
Intra
|
BRCA1 | P38398 | UIMC1 | Homo sapiens | Q96RL1 | 17525340 | |
|
Intra
|
BRCA1 | P38398 | UIMC1 | Homo sapiens | Q96RL1 | 29656893 | |
|
Intra
|
BRCA1 | P38398 | UIMC1 | Homo sapiens | Q96RL1 | 17525340 | |
|
Intra
|
BRCA1 | P38398 | UIMC1 | Homo sapiens | Q96RL1 | 17525340 | |
|
Intra
|
BRCA1 | P38398 | RBBP8 | Homo sapiens | Q99708 | 17525340 | |
|
Intra
|
BRCA1 | P38398 | RBBP8 | Homo sapiens | Q99708 | 11739404 | |
|
Intra
|
BRCA1 | P38398 | RBBP8 | Homo sapiens | Q99708 | 9811458 | |
|
Intra
|
BRCA1 | P38398 | RBBP8 | Homo sapiens | Q99708 | 34591612 | |
|
Intra
|
BRCA1 | P38398 | RBBP8 | Homo sapiens | Q99708 | 19369211 | |
|
Intra
|
BRCA1 | P38398 | RBBP8 | Homo sapiens | Q99708 | 17525340 | |
|
Intra
|
BRCA1 | P38398 | RBBP8 | Homo sapiens | Q99708 | 9811458 | |
|
Intra
|
BRCA1 | P38398 | RBBP8 | Homo sapiens | Q99708 | 29656893 | |
|
Intra
|
BRCA1 | P38398 | ESR1 | Homo sapiens | P03372 | 15674350 | |
|
Intra
|
BRCA1 | P38398 | ESR1 | Homo sapiens | P03372 | 11244506 | |
|
Intra
|
BRCA1 | P38398 | ESR1 | Homo sapiens | P03372 | 15674350 | |
|
Intra
|
BRCA1 | P38398 | ESR1 | Homo sapiens | P03372 | 15674350 | |
|
Intra
|
BRCA1 | P38398 | ESR2 | Homo sapiens | Q92731 | 21951318 | |
|
Intra
|
BRCA1 | P38398 | SUMO1 | Homo sapiens | P63165 | 20016594 | |
|
Intra
|
BRCA1 | P38398 | SUMO1 | Homo sapiens | P63165 | 20016594 | |
|
Intra
|
BRCA1 | P38398 | SUMO1 | Homo sapiens | P63165 | 20016594 | |
|
Cross
|
BRCA1 | P38398 | Ezh2 | Mus musculus | Q61188 | 23624935 | |
|
Cross
|
BRCA1 | P38398 | Ezh2 | Mus musculus | Q61188 | 23624935 | |
|
Intra
|
BRCA1 | P38398 | CHEK1 | Homo sapiens | O14757 | 11836499 |
BRCA1 Antibodies
| Referencia número | Nombre del producto | Aplicación | Reactivity |
|---|---|---|---|
| HY-P80489 | BRCA1 Antibody (YA819) | IHC-P | Human, Mouse |
| HY-P80573 | BRCA1 Antibody | WB, IHC-F, IHC-P, ICC/IF, ELISA | Human, Rat |
| HY-P84289 | BRCA1 Antibody (YA3986) | IHC-P, ELISA | Human |
| HY-P84289A | BRCA1 Antibody (YA3986)(PBS only) | IHC-P, ELISA | Human |
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Breast-Ovarian Cancer, Familial 1 |
|
|
| Fanconi Anemia, Complementation Group S |
|
|
| Pancreatic Cancer 4 |
|
|
| Hereditary Breast Ovarian Cancer Syndrome |
|
|
| Ovarian Cancer 1 |
|
|
| Palmoplantar Keratoderma, Punctate Type Ii |
|
|
| Bilateral Breast Cancer |
|
|
| Breast-Ovarian Cancer, Familial 2 |
|
|
| Ovarian Cancer |
|
|
| Breast Cancer |
|
|
| Pancreatic Cancer |
|
|
| Fanconi Anemia, Complementation Group A |
|
|
| Endometrial Cancer |
|
|
| Bap1 Tumor Predisposition Syndrome |
|
|
| Inherited Cancer-Predisposing Syndrome |
|
|
| Rhabdomyosarcoma |
|
|
| Cholangiocarcinoma |
|
|
| Lung Cancer |
|
|
| Colorectal Cancer |
|
|
| Fallopian Tube Carcinoma |
|
|
| Primary Peritoneal Carcinoma |
|
|
| Hereditary Breast Cancer |
|
|
| Polyposis Syndrome, Hereditary Mixed, 1 |
|
|
| Hereditary Site-Specific Ovarian Cancer Syndrome |
|
|
| Li-Fraumeni Syndrome |
|
|
| Serous Cystadenocarcinoma |
|
|
| Fallopian Tube Disease |
|
|
| Cystadenocarcinoma |
|
|
| Cystadenoma |
|
|
| Nijmegen Breakage Syndrome |
|
|
| Bloom Syndrome |
|
|
| Ataxia-Telangiectasia |
|
|
| Lynch Syndrome |
|
|
| Female Breast Cancer |
|
|
| Prostate Cancer |
|
|
| Breast Ductal Carcinoma |
|
|
| Riddle Syndrome |
|
|
| Cancerophobia |
|
|
| Nosophobia |
|
|
| Sporadic Breast Cancer |
|
|
| Basaloid Lung Carcinoma |
|
|
| Ovarian Cystadenoma |
|
|
| Werner Syndrome |
|
|
| Ovarian Serous Cystadenocarcinoma |
|
|
| Cowden Syndrome |
|
|
| Breast Carcinoma In Situ |
|
|
| Peritoneum Cancer |
|
|
| Cowden Syndrome 1 |
|
|
| Lobular Neoplasia |
|
|
| In Situ Carcinoma |
|
|
| Pre-Malignant Neoplasm |
|
|
| Breast Disease |
|
|
| Lynch Syndrome I |
|
|
| Breast Lobular Carcinoma |
|
|
| Premature Menopause |
|
|
| Ductal Carcinoma In Situ |
|
|
| Ovarian Disease |
|
|
| Hypertrophy Of Breast |
|
|
| Papillary Serous Adenocarcinoma |
|
|
| Fanconi Anemia, Complementation Group N |
|
|
| Radiation Induced Cancer |
|
|
| Ovarian Carcinosarcoma |
|
|
| Dysplastic Nevus Syndrome |
|
|
| Breast Benign Neoplasm |
|
|
| Thoracic Benign Neoplasm |
|
|
| Xeroderma Pigmentosum, Variant Type |
|
|
| Canavan Disease |
|
|
| Diffuse Gastric And Lobular Breast Cancer Syndrome |
|
|
| Diffuse Gastric Cancer |
|
|
| Endosalpingiosis |
|
|
| Cockayne Syndrome |
|
|
| Synchronous Bilateral Breast Carcinoma |
|
|
| Leiomyosarcoma |
|
|
| Estrogen-Receptor Negative Breast Cancer |
|
|
| Retinoblastoma |
|
|
| Cornelia De Lange Syndrome |
|
|
| Ovary Transitional Cell Carcinoma |
|
|
| Dysgerminoma |
|
|
| Malignant Ovarian Surface Epithelial-Stromal Neoplasm |
|
|
| Adenoid Cystic Carcinoma |
|
|
| Ewing Sarcoma |
|
|
| Ovarian Benign Neoplasm |
|
|
| Ovarian Cystadenocarcinoma |
|
|
| Autosomal Recessive Cerebellar Ataxia |
|
|
| Ovary Adenocarcinoma |
|
|
| Familiar Ovarian Carcinoma |
|
|
| Fanconi Anemia, Complementation Group D1 |
|
|
| Fallopian Tube Adenocarcinoma |
|
|
| Ovary Epithelial Cancer |
|
|
| Neural Tube Defects |
|
|
| Mismatch Repair Cancer Syndrome |
|
|
| Bladder Cancer |
|
|
| Hepatocellular Carcinoma |
|
|
| Endometrial Serous Adenocarcinoma |
|
|
| Fanconi Anemia, Complementation Group J |
|
|
| Ovarian Serous Cystadenofibroma |
|
|
| Glioblastoma |
|
|
| Female Reproductive Endometrioid Cancer |
|
|
| Breast Fibroadenoma |
|
|
| Ovarian Clear Cell Carcinoma |
|
|
| Vaginal Cancer |
|
|
| Ovarian Cyst |
|
|
| Estrogen-Receptor Positive Breast Cancer |
|
|
| Ovarian Serous Adenofibroma |
|
|
| Papillary Adenocarcinoma |
|
|
| Muir-Torre Syndrome |
|
|
| Ovarian Serous Carcinoma |
|
|
| Physical Disorder |
|
|
| Mixed Cell Type Cancer |
|
|
| Gastric Cancer |
|
|
| Fanconi Anemia, Complementation Group D2 |
|
|
| Uterine Corpus Cancer |
|
|
| Familial Retinoblastoma |
|
|
| Deficiency Anemia |
|
|
| Hereditary Ataxia |
|
|
| Cerebellar Disease |
|
|
| Thoracic Cancer |
|
|
| Medulloblastoma |
|
|
| Aplastic Anemia |
|
|
| Testicular Disease |
|
|
| Melanoma, Cutaneous Malignant 1 |
|
|
| Uterine Body Mixed Cancer |
|
|
| Microcephaly |
|
|
| Seckel Syndrome |
|
|
| Breast Adenocarcinoma |
|
|
| Osteoporosis |
|
|
| Neuroblastoma |
|
|
| Esophageal Cancer |
|
|
| Adrenal Cortical Carcinoma |
|
|
| Basal Cell Nevus Syndrome |
|
|
| Testicular Cancer |
|
|
| Melanoma, Uveal |
|
|
| Renal Cell Carcinoma, Nonpapillary |
|
|
| Wilms Tumor 1 |
|
|
| Leukemia, Acute Myeloid |
|
|
| Eye Disease |
|
|
| Peripheral Nervous System Disease |
|
|
| Congenital Nervous System Abnormality |
|
|
| Nervous System Disease |
|
|
| Retinitis Pigmentosa |
|
|
Related Agents
- Approval
- Clinical Phase
- Pre-clinical Phase
Approval
| Referencia número | Nombre del producto |
Efecto
|
Pureza |
Rare Diseases
|
|---|---|---|---|---|
| HY-10617A | Rucaparib | Inhibitor | 99.96% | Yes |
| HY-114778 | Fluzoparib | Inhibitor | 99.96% | Unkown |
| HY-10617 | Rucaparib phosphate | Inhibitor | 99.76% | Yes |
| HY-102003 | Rucaparib monocamsylate | Inhibitor | 99.91% | Yes |
| HY-102003A | Rucaparib camsylate | Inhibitor | / | Unkown |
Clinical Phase
| Referencia número | Nombre del producto |
Efecto
|
Pureza |
Phase
|
|---|---|---|---|---|
| HY-160700 | TNG348 | Inhibitor | 99.74% | Phase 2 |
| HY-115552 | Simmiparib | Inhibitor | 99.01% | Phase 1 |
Pre-clinical Phase
| Referencia número | Nombre del producto |
Efecto
|
Pureza |
Rare Diseases
|
|---|---|---|---|---|
| HY-124691 | D-I03 | Inhibitor | 99.70% | Unkown |
| HY-W327122 | BAP1-IN-1 | Inhibitor | 99.86% | Unkown |
| HY-139156 | SK-575 | Inhibitor | 99.86% | Unkown |
| HY-126020 | Bractoppin | Inhibitor | 99.90% | Unkown |
| HY-162859 | AB25583 | Inhibitor | 99.87% | Unkown |
| HY-162706 | BSJ-5-63 | Degrader | 99.97% | Unkown |
| HY-139329 | CDK12-IN-6 | Inhibitor | 99.15% | Unkown |
| HY-174143 | EXO1-IN-1 | Inducer | 99.00% | Unkown |
| HY-W116007 | Octamethylcyclotetrasiloxane | Inhibitor | 99.86% | Unkown |
| HY-179289 | ZLY025 | 99.40% | Unkown | |
| HY-100862 | BRCA1-IN-2 | Inhibitor | 98.12% | Unkown |
| HY-RS01593 | BRCA1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-139328 | CDK12-IN-5 | Inhibitor | 98.03% | Unkown |
| HY-181692 | PROTAC RNF4 degrader-1 | / | Unkown | |
| HY-146336 | PARP1/2/TNKS1/2-IN-1 | 98.66% | Unkown | |
| HY-158346 | RP-2119 | Inhibitor | 99.94% | Unkown |
| HY-162477 | TS-24 | 98.96% | Unkown | |
| HY-171171 | NERx 329 | Inhibitor | / | Unkown |
| HY-179585 | DD-CIP2 | Inducer | / | Unkown |
| HY-179219S | RTx-303 | Inhibitor | / | Unkown |
| HY-181035 | DN1679 | Degrader | / | Unkown |
| HY-183630 | AZD4956 | Inhibitor | / | Unkown |
| HY-10617AS1 | Rucaparib-d3 | Inhibitor | / | Unkown |
| HY-120750 | A 62176 hydrochloride | / | Unkown | |
| HY-122583 | D-G23 | Inhibitor | / | Unkown |
| HY-125010 | Dicycloplatin | Inducer | / | Unkown |
| HY-132885 | PARP/EZH2-IN-1 | Inhibitor | / | Unkown |
| HY-139327 | CDK12-IN-4 | Inhibitor | / | Unkown |
| HY-14687 | (rac)-Talazoparib | Inhibitor | / | Unkown |
| HY-149003 | PARP1-IN-10 | / | Unkown | |
| HY-155246 | PARP1-IN-15 | / | Unkown | |
| HY-155766 | PARP1-IN-14 | / | Unkown | |
| HY-157212 | PARP-1/Proteasome-IN-1 | / | Unkown | |
| HY-168094 | PARP1-IN-30 | Inhibitor | / | Unkown |
| HY-174446 | PARP1-IN-39 | Inhibitor | / | Unkown |
| HY-175257 | Theophylline-platinum(IV) prodrug-1 | / | Unkown | |
| HY-179582 | PROTAC DNPH1 Degrader 1 | Degrader | / | Unkown |
| HY-181842 | PARP1/ERK IN-1 | / | Unkown | |
| HY-183363 | USP1-IN-17 | Inhibitor | / | Unkown |
| HY-183765 | PARP1/PKM2-IN-1 | Inhibitor | / | Unkown |
| HY-174563 | Human OLA1 mRNA | / | Unkown | |
| HY-RS16661 | Brca1 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS23096 | Brca1 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-100863 | BRCA1-IN-1 | Inhibitor | / | Unkown |
| Referencia número | Nombre del producto |
Efecto
|
Pureza |
Rare Diseases
|
|---|---|---|---|---|
| HY-P990873 | Anti-BRCA1 Antibody (BR64) | Inhibitor | / | Unkown |
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