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United States

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Referencia número: HY-139832

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MCX 28

MCX 28, a triple PI3K/mTOR/PIM inhibitor, displays low nanomolar activity.

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No. CAS: 1414453-58-9
Fòrmula: C₂₅H₁₉N₅O₄S₃
Peso molecular:549.64

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (277 KB)

MCX 28 Chemical Structure

No. CAS: 1414453-58-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

MCX 28, a triple PI3K/mTOR/PIM inhibitor, displays low nanomolar activity.

Ver todos los productos específicos de isoformas PI3K :

Ver todos los productos específicos de isoformas mTOR :

Chemical Information

No. CAS 1414453-58-9
Peso molecular 549.64
Fòrmula C₂₅H₁₉N₅O₄S₃
SMILES

CC1=C(C2=CN=C(OC)C(NS3(=O)=O)=C2)SC4=C1N=CN=C4C5=CC=C(CNC(C6=CC3=CC=C6)=O)S5
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (277 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Martínez-González S, et al. Macrocyclization as a Source of Desired Polypharmacology. Discovery of Triple PI3K/mTOR/PIM Inhibitors. ACS Med Chem Lett. 2021 Nov 2;12(11):1794-1801. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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MCX 28

Ver todos los productos específicos de isoformas PI3K

Ver todos los productos específicos de isoformas mTOR

Actividad biológica

Descripciòn

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

MCX 28 Related Classifications

HY-139832 Related Classifications

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