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United States

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Referencia número: HY-162027

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PB118

PB118 is a potent inhibitor of HDAC6 that plays an important role in the pathophysiology of Alzheimer's disease.

Para uso exclusivo en investigación. No vendemos a pacientes.

Fòrmula: C₁₈H₁₉FN₂O₂
Peso molecular:314.35

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

PB118 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

PB118 is a potent inhibitor of HDAC6 that plays an important role in the pathophysiology of Alzheimer's disease^[1].

Ver todos los productos específicos de isoformas HDAC :

Chemical Information

Peso molecular 314.35
Fòrmula C₁₈H₁₉FN₂O₂
SMILES

FC(C=C(C(NO)=O)C=C1)=C1CN2C3=CC=CC=C3CCCC2
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Prasenjit Mondal, et al. Structure-Based Discovery of A Small Molecule Inhibitor of Histone Deacetylase 6 (HDAC6) that Significantly Reduces Alzheimer's Disease Neuropathology. Adv Sci (Weinh). 2023 Nov 21:e2304545. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Actividad biológica
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Chemical Information
Pureza y Documentación
Referencias

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PB118

Ver todos los productos específicos de isoformas HDAC

Actividad biológica

Descripciòn

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

PB118 Related Classifications

HY-162027 Related Classifications

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Keywords

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