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Referencia número: HY-139144

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YM-08

YM-08 (Compounds 7a) is a brain-penetrant inhibitors of SIRT2,with the IC₅₀ of 19.9 μM. YM-08 also is inhibitor of Hsp70.

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No. CAS: 812647-88-4
Fòrmula: C₁₉H₁₇N₃OS₂
Peso molecular:367.49

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

YM-08 Chemical Structure

No. CAS: 812647-88-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Actividad biológica

Descripciòn

YM-08 (Compounds 7a) is a brain-penetrant inhibitors of SIRT2,with the IC₅₀ of 19.9 μM. YM-08 also is inhibitor of Hsp70^[1].

IC₅₀ & Target

HSP70

Ver todos los productos específicos de isoformas Sirtuin :

Ver todos los productos específicos de isoformas HSP :

Chemical Information

No. CAS 812647-88-4
Peso molecular 367.49
Fòrmula C₁₉H₁₇N₃OS₂
SMILES

O=C1N(CC)/C(S/C1=C2SC3=CC=CC=C3N/2C)=C\C4=NC=CC=C4
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Abbotto E, et al. Novel Thiazole-Based SIRT2 Inhibitors Discovered via Molecular Modelling Studies and Enzymatic Assays. Pharmaceuticals (Basel). 2023;16(9):1316. Published 2023 Sep 18. [Content Brief]

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Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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YM-08

Ver todos los productos específicos de isoformas Sirtuin

Ver todos los productos específicos de isoformas HSP

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Descripciòn

IC50 & Target

Chemical Information

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YM-08 Related Classifications

HY-139144 Related Classifications

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